13 results about "Delayed healing" patented technology

The invention relates to the technical field of anastomats, in particular to a stably-propelled electric endoscope anastomat which comprises an anastomat gun body, a straight pipe fixed to one end of the anastomat gun body and an insertion pipe inserted to one end of the straight pipe. The healing promoting liquid is uniformly sprayed on a fresh cut wound surface, and the sprayed liquid can quickly form a protective film with strong adhesiveness on the wound surface, so that stimulation of seroperitoneum and instrument friction to the wound surface is effectively isolated, the risk of postoperative tissue adhesion is reduced, delayed healing of the wound surface due to overlong exposure time is avoided, immediate protection is provided for early healing of an anastomotic stoma, and the wound surface healing rate is increased. The defects that existing equipment can only conduct cutting anastomosis and cannot guarantee wound repairing conditions synchronously are overcome, the healing period can be shortened, the risk of complications such as anastomotic stoma errhysis and cracking is reduced, and the clinical requirement for efficient and safe healing is met.

The invention discloses a surgical incision healing state image intelligent evaluation method and system, and belongs to the technical field of image analysis and medical diagnosis assistion.The method comprises the steps that a preprocessed incision image is generated through dual-path self-adaptive image enhancement processing, and an incision area is extracted through a semantic segmentation network fused by a multi-scale feature pyramid; a comprehensive healing score is generated based on an adaptive feature weighted fusion strategy, healing trend prediction is constructed through a time sequence tracking module, an abnormal deterioration risk is identified, and an incision state is classified into one of normal healing, delayed healing, incision infection and incision cracking by adopting a multi-classification decision network. According to the method, the technical problems of insufficient image preprocessing capability, low incision segmentation precision, incomplete feature extraction, lack of time sequence tracking capability, single classification decision and the like in the prior art are solved, accurate, comprehensive and dynamic evaluation of the healing state of the surgical incision is realized, and reliable decision support is provided for clinic.

This invention discloses a novel adjustable intramedullary nail, comprising a hollow main nail, a proximal end of the nail, and a main body of the nail, which are integrally formed. The diameter of the proximal end of the nail is larger than that of the main body. Multiple through-holes for dynamic screws are provided at the proximal end of the nail. An adjustment hole is provided on the main body of the nail, away from the proximal end. A dynamic bone screw is installed in each of the dynamic screw holes and can move axially along the holes. A tail cap is installed on the proximal side of the nail, and an elastomer is placed between the tail cap and the dynamic bone screw. An absorbable washer is placed distal to the dynamic bone screw to support it. An adjustment device for adjusting the stress at the fracture ends is provided on the main body of the nail, which can adjust the stress at the fracture ends according to the specific fracture conditions, avoid stress shielding at the fracture ends, accelerate fracture healing, reduce delayed healing and nonunion, and decrease the incidence of refracture after removal of the intramedullary nail.

The invention relates to the field of diabetic foot ulcer, and discloses a diabetic foot ulcer wound edge skin-derived extracellular vesicle as well as a preparation method and application thereof. The preparation method comprises the following steps: pretreating diabetic foot ulcer wound edge skin tissues to obtain tissue fragments; the method comprises the following steps: mixing type IV collagenase and DNaseI enzyme in a DMEM (Dulbecco Modified Eagle Medium) high-glucose culture medium to prepare a tissue dissociation solution; carrying out primary dissociation by using pancreatin digestive juice, and then carrying out secondary dissociation by using tissue dissociation liquid; sequentially and alternately carrying out gradient size filtration and differential centrifugation on the filtrate, and collecting supernate; performing ultra-high-speed centrifugation, ultra-filtration and gradient needle type filtration on the supernate; and performing ultra-high-speed centrifugation again to obtain the diabetic foot ulcer wound edge skin-derived extracellular vesicles. The concentration of the obtained EVs is 3.29 mg / mL, and the characteristics of delayed healing and insufficient collagen deposition can be stably obtained by injecting the EVs into normal mice.

The present application relates to a leg rest position adjustment process of Braun-type orthopedic traction, which comprises the following steps: S1, preliminary resting; S2, support position adjustment; S3, construction of rehabilitation information base. One aspect of the present application is based on the linkage adjustment of the angle, height and relative spacing between support points to form an angle leg rest support in line with human mechanics, which not only reduces the difficulty of patient posture adjustment and the difficulty of medical staff operation, but also greatly reduces the risk of limb injury, body position discomfort, muscle tension, pressure sores and other complications caused by traction, and also reduces the possibility of causing deformity healing or delayed healing rate. The other aspect is based on a health-related information system to collect and analyze data to obtain the reference parameters close to the force line of different lower limb leg rest positions, thereby constructing a traction closed loop of precise execution-data feedback-continuous optimization.

The application discloses a bidirectional adjustable elastic intramedullary nail, which comprises an intramedullary nail main nail with a hollow structure, wherein the intramedullary nail main nail comprises an intramedullary nail proximal end and an intramedullary nail body in an integrated structure, the diameter of the intramedullary nail proximal end is larger than that of the intramedullary nail body, a power screw hole penetrating through the intramedullary nail proximal end is arranged, an adjusting hole is arranged on the intramedullary nail body away from the intramedullary nail proximal end, a power bone screw is installed in the power screw hole, the power bone screw can move axially along the power screw hole, a tail cap is installed on the intramedullary nail proximal end side, an elastic body is arranged between the tail cap and the power bone screw, an absorbable gasket is arranged below the power bone screw, the absorbable gasket supports the power bone screw, and an adjusting device for adjusting the stress of a fracture end is arranged on the intramedullary nail body. The stress of the fracture end can be adjusted according to the specific condition of the fracture, the stress of the fracture end is avoided to be blocked, the fracture healing is accelerated, the delayed healing and non-healing of the fracture are reduced, and the incidence of the fracture after the intramedullary nail is removed is reduced.

The invention discloses a method for constructing an anal fistula model based on a rat perianal chronic infectious wound, and belongs to the field of experimental animal modeling, the method comprises the following steps: selecting a 6-8-week male SD rat, adopting a supine position and raising the buttocks to fully expose an operation area, firstly cutting off full skin and subcutaneous tissue at a preset site beside the anus, exposing a superficial fascia layer, and then cutting off a subcutaneous tissue at a preset site beside the anus; and preparing a standardized skin defect wound surface. Then, a quantitative bacterial suspension is implanted into the basal part and the edge subcutaneous part of the wound surface by utilizing a multi-point injection technology, so that pathogenic bacteria form a stable infection focus in the deep layer of soft tissue, and the endogenous infection process evolved from perianal abscess to anal fistula is simulated. The model successfully reproduces the core characteristics of high bacterial load, chronic property, delayed healing and the like of the clinical anal fistula wound surface. The operation process is standard, the success rate is high, the individual difference is small, and a stable and reliable experimental evaluation platform highly simulating the clinical environment is provided for evaluating biological materials with anti-infection, anti-oxidation and healing promoting functions.

The present application relates to the technical field of anastomat, in particular to a stable electric endoscope anastomat, which comprises an anastomat gun body, a straight pipe fixed at one end of the anastomat gun body, and a plug-in pipe plugged at one end of the straight pipe. The limit slide and cutting knife are moved by the push rod, the liquid injection assembly is triggered to spray liquid in order, the healing-promoting liquid is uniformly sprayed on the fresh cutting wound surface, the sprayed liquid can quickly form a protective film with strong adhesion on the wound surface, effectively isolating the stimulation of abdominal effusion and instrument friction on the wound surface, reducing the risk of postoperative tissue adhesion and avoiding delayed healing of the wound surface due to prolonged exposure time, providing immediate protection for early healing of the anastomotic stoma, not only making up for the shortcomings of the existing equipment that can only cut and anastomose but cannot simultaneously ensure the repair conditions of the wound surface, but also shortening the healing period and reducing the risk of complications such as anastomotic stoma bleeding and dehiscence, meeting the clinical demand for efficient and safe healing.

A wearable pressure-relief brace has been developed to treat tennis elbow by redistributing forces away from the lateral epicondyle. Unlike prior art, which primarily relies on compression to alleviate symptoms, this innovation addresses the root cause of prolonged pain and delayed healing: repetitive nighttime pressure on injured elbow tissues during side sleeping. Referenced research highlights how such pressures exacerbate the initial sprain or strain of the common extensors at their origin at the lateral epicondyle. The described apparatus minimizes these aggravating forces, enabling rapid relief and recovery. This offloading brace represents a significant advancement over passive restraints, offering improved protection, comfort, freedom of movement, and compliance, particularly during sleep.

The present application relates to the Brown orthopedic traction device, it includes the leg rest structure and traction structure, wherein the leg rest structure includes the chassis, the calf support and the thigh support, the traction structure includes the traction frame, the frame wheel, the traction rope, the traction power device, the traction bow. One aspect of the present application not only reduces the difficulty of patient posture adjustment and operation, but also greatly reduces the risk of limb injury, body position discomfort, muscle tension, pressure sores and other complications caused by traction, and also reduces the risk of deformity healing or delayed healing rate; on the other hand, based on the height and angle adjustment of the traction frame, the position and traction direction of the traction bow are adjusted, without the need for further leg rest position adjustment, reducing the difficulty of traction; at the same time, based on the cooperation of the length and angle of the four-section traction rope, not only can the current traction be continued in the dynamic balance mode, but also the traction position and angle can be kept unchanged to implement the traction force change, so as to improve the traction direction and mechanical axis coincidence degree, thereby reducing the risk of traction injury.

According to the hydrogel with the multifunctional regulation and control capacity and the preparation method thereof, Que-coated HZ hydrogel is obtained through physical loading of QueNPs and crosslinking of modified hyaluronic acid and Zn < 2 + >, the problems that solubility of quercetin in a water phase is limited, an extracellular matrix is possibly simulated, and cell migration and proliferation are promoted are solved, Zn < 2 + > is crosslinked to the hydrogel through a metallic bond, and the HZ hydrogel realizes continuous release of Zn < 2 + >, so that the survival rate of quercetin is increased. Growth of bacteria and fungi is inhibited, delayed healing caused by infection is reduced, gelatin-encapsulated quercetin nanoparticles are physically loaded on the hydrogel, the hydrogel is endowed with remarkable antioxidant and anti-inflammatory functions, quercetin can relieve oxidative stress, especially mitochondrial damage, mitochondrial active oxygen can be eliminated, membrane potential damage can be relieved, and the hydrogel has a good anti-inflammatory effect. Therefore, the mitochondrial function is protected.

This invention relates to the field of antibacterial bandage production technology, and discloses a method for preparing an antibacterial polyester bandage and its spinning apparatus, comprising the following steps: Step 1: Fiber mixing and opening, S1, mixing polyester fiber, bamboo fiber, and silver ion antibacterial fiber in a certain proportion; S2, opening the fibers using a fiber opening machine to ensure thorough and uniform mixing; Step 2: Roving preparation, S3, carding the mixed fibers into fiber slivers using a carding machine; S4, using a drawing frame to perform three rounds of drawing and stretching on the fiber slivers to improve uniformity. This invention has the following advantages and effects: through the triple synergistic antibacterial mechanism of bamboo fiber, silver ion fiber, and nano-silver, it achieves natural antibacterial, long-lasting antibacterial, and instantaneous bactericidal effects, reducing the risk of drug resistance. Simultaneously, the mixing of silver ion fiber and polyester fiber optimizes mechanical strength, balancing breathability and durability, thus reducing the poor breathability of synthetic fiber-based bandages, which can easily lead to damp wounds and delayed healing.

The present application relates to the field of medical wound care, and particularly relates to a wound dressing based on flexible electronic technology, comprising a dressing main body and an adaptive system; the adaptive system comprises: a flexible sensing module for real-time monitoring of multi-dimensional electrical signals at the wound site, and converting the multi-dimensional electrical signals into multi-dimensional digital signals; a feedback adjustment module for generating corresponding tension adjustment instructions based on the multi-dimensional digital signals and a preset tension threshold; a flexible braking module for applying an adaptive pulling force to the skin around the wound, so that the actual tension of the wound is maintained within the preset tension threshold; a communication module for wireless connection with an external terminal; and a power supply module for providing power to each module. The present application can realize real-time sensing and adaptive adjustment of wound tension, effectively buffer the skin stretching and tension impact caused by human activity, reduce the incidence of wound cracking, delayed healing and scar hyperplasia, and at the same time realize multi-parameter monitoring and remote intelligent nursing of the wound.