High substitution degree carboxymethyl indianbread polysaccharide and its preparation method and uses

A Poria cocos polysaccharide technology with a high degree of substitution is applied to metabolic diseases, medical formulas, medical preparations of non-active ingredients, etc. It can solve the problems of limiting the clinical application range of CMP, difficult separation and removal of impurities, and difficult industrial production, etc. Environmental protection, shortening of reaction time, and improvement of solubility
CN1970579AActive Publication Date: 2007-05-30HUNAN BUTIAN PHARMA
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
HUNAN BUTIAN PHARMA
Publication Date
2007-05-30

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Abstract

The invention discloses a carboxymethyl pachyman (CMP) with high-degree of substitution and making method and application, which is characterized by the following: adopting water or water alcohol solution as dielectric; proceeding substitution reaction for pachyman, chloroacetic acid and fitful excessive sodium hydroxide to obtain CMP without vibrating technique and equipment; improving CMP D / S and solubility to reach injection need.
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Description

technical field

[0001] The invention belongs to the field of anti-tumor macromolecule polysaccharides, and in particular relates to carboxymethylpachymaran (CMP) with a high degree of carboxymethyl substitution as a biological response regulator, a preparation method and an application thereof. Background technique

[0002] Poria cocos is the dry sclerotia of Poria cocos (Schw.) Wolf, a plant of Polyporaceae. It has been one of the "four monarchs and eight treasures" of traditional Chinese medicine since ancient times. The component pachyan has a β(1→3)-bonded glucose linear structure and a β(1→6)-bonded glucosyl branched structure. Tests have shown that Poria cocos polysaccharide without chemical modification has no anti-tumor activity, and the decoction yield of Poria cocos in boiling water does not exceed 1%. The chemically modified carboxymethylpachypolysaccharide (CMP) obviously improves the water solubility of the polysaccharide, which is beneficial to the absorption ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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