37 results about "Ethyl phosphonate" patented technology

The invention relates to a method for microwave synthesis of organic phosphine-functionalized imidazolium-based ionic liquid. The method is characterized by comprising the following steps of: mixing imidazole compounds with bromo-alkyl diphenyl phosphine oxide, bromo-alkyl phenyl ethyl phosphonate or bromo-alkyl diethyl phosphonate at a molar ratio of 1:(1-1.2) during preparation, putting the mixture into a microwave reacting device, reacting for 60-150 minutes at the microwave power of 280-500 W and the reaction temperature of 80-120 DEG C to obtain crude products, and removing unreacted raw materials, so as to obtain the organic phosphine-functionalized imidazolium-based ionic liquid. According to the method, a novel organic phosphine-functionalized imidazolium-based ionic liquid is provided and is simultaneously synthesized by utilizing microwave radiation and heating in an efficient, quick and low-cost manner, the reaction time is greatly shortened, the reaction rate is improved, and the yields of all the prepared ionic liquids are relatively high; the raw material utilization ratio is relatively high, no by-product is produced, and the synthesized ionic liquid is easy to purify.

The invention relates to high-adhesion high-gloss black UV inkjet ink which comprises, by weight, 10-20 parts of black color paste, 10-20 parts of polyurethane acrylate resin, 50-70 parts of reactivediluents, 6-10 parts of photoinitiator and 3-4 parts of auxiliaries. The reactive diluents include, by mass part, a first reactive diluent, a second reactive diluent and a third reactive diluent according to a consumption ratio of 2-3:1-2:2-3; the photoinitiator is at least one of 1-hydroxy-cyclohexylbenzophenone, 2, 4, 6-trimethylbenzoyl-diphenyl phosphine oxide and 2, 4, 6-trimethylbenzoyl ethylphenyl phosphoinate; the auxiliaries include defoamer, leveling agent, adhesion accelerant and polymerization retarder. The invention provides a preparation method and application of the high-adhesion high-gloss black UV inkjet ink. The black UV inkjet ink has the advantages of high gloss value, high adhesion and high hardness.

The invention relates to a weed control composition for plant haulm treatment, which comprises compound an and compound b with the general formula (1) as active compositions, wherein b is selected from any of the following compounds, tribenuron-methyl, thifensulfuron methyl, metsulfuron-methyl, chlorsulfuron, bensulfuron-methyl, isoproturon, siduron, quinclorac, mefenacet,.alachlor, acetochlor, butachlor and metolachlor. The invention also discloses the preparation of the weed control composition, the method for weeds removing, and the use of the weed control composition as herbicide for haulm processing.

The invention discloses a process for preparing methyl ethylphosphinate and methyl ethylphosphinate aluminum salt, and belongs to the technical field of flame-retardant materials, aiming to solve thedifficulty in realization of industrial production of the methyl ethylphosphinate in the prior art. The process for preparing the methyl ethylphosphinate and the methyl ethylphosphinate aluminum saltincludes taking sodium iodide as a catalyst, and reacting methyl diethylphosphinate at the temperature of 80-180 DEG C to generate the methyl ethylphosphinate; reacting the methyl ethylphosphinate with aluminum trichloride in a solvent to obtain the methyl ethylphosphinate aluminum salt. The process has the advantages that the low-purity methyl diethylphosphinate serves as a raw material, the methyl ethylphosphinate is obtained under a moderate condition and at high yield, and industrialization is realized easily; methyl ethylphosphinate aluminum flame retardants with high phosphorus content are further obtained, and are environment-friendly halogen-free flame retardants for polymer materials.

A method of treating a citrus plant is provided to reduce the incidence of one or more insect-vectored bacterial infections such as citrus greening. The method comprises the step of applying a treatment composition one or more times to the plant, wherein the treatment composition comprises an effective amount of aluminum tris(O-ethyl phosphonate).

The invention relates to a triazine triphenyl phosphinic acid ethyl ester flame retardant composition and an application method thereof. The flame retardant composition is prepared by compounding and uniformly mixing any two, three or four of melamine cyanurate (MCA), melamine pyrophosphate (MPP), 9, 10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide (DOPO) and pentaerythritol methyl silicate (PEMS) with triazine triphenyl phosphinic acid ethyl ester (TTPE) at any proportion, wherein the weight part of the TTPE is greater than zero. The flame retardant composition provided by the invention has the advantages of multielement synergic effect, good flame retardancy, good compatibility with materials, low cost, zero halogen, environmental protection and the like, can be used as a flame retardant for polyester PET, polyester PBT, polyurethane, polypropylene, epoxy resin and other materials, and has excellent application and popularization prospects.

The invention relates to organic phosphine-functionalized pyridine-based ionic liquid and a preparation method thereof. The preparation method is characterized by comprising the following steps of: mixing pyridine compounds with bromo-alkyl diphenyl phosphine oxide, bromo-alkyl phenyl ethyl phosphonate or bromo-alkyl diethyl phosphonate at a molar ratio of 1:(1-1.2), adding organic solvents, putting the mixture into a microwave reacting device, carrying out stirring for reaction for 60-150 minutes at the microwave power of 350-500 W and the reaction temperature of 80-110 DEG C to obtain crude products, and removing unreacted raw materials, so as to obtain the organic phosphine-functionalized pyridine-based ionic liquid. According to the method, the novel organic phosphine-functionalized pyridine-based ionic liquid is provided and simultaneously is synthesized by utilizing microwave heating, the reaction time is greatly shortened, and the reaction rate is improved; the raw material utilization ratio is relatively high, no by-product is produced, and the synthesized ionic liquid is easy to purify and has the characteristics of high efficiency, speediness and low cost.

The invention relates to an Axitinib sustained-release implant for treating a solid tumor, which is characterized in that: the sustained-release implant contains an effective anticancer amount of Axitinib and sustained-release excipients and a certain amount of sustained-release regulator. The solid tumors include the liver cancer, the lung cancer, the esophageal canner, the gastric canner, the breast canner, the ovarian canner, the prostate canner, the bladder canner and the rectum canner. The sustained-release excipients are mainly a copolymer of polylactic acid, glycollic acid and hydroxyacetic acid and one of the three materials, polifeprosan, poly-(L-lactide-co-ethyl phosphonate) and Poly(L-lactide-co-propyl phosphonate) or a combination of the three materials, in the degradation and absorption process of which the Axitinib is sustainedly released to part of the tumor, thus the entire toxicity of the Axitinib is significantly reduced while an effective medicine consistency is maintained on part of the tumor. That the sustained-release implant is implanted inside part of the tumor can not only reduce the entire toxicity of the Axitinib, but also enhance the medicine consistency on part of the tumor, thereby increasing the curing effect of non-operative therapeutics such as chemotherapeutic drugs and radiotherapy.

The invention relates to a preparation method of 2,4,6-trimethyl benzoyl phenyl ethyl phosphonate, and in particular relates to a method for preparing 2,4,6-trimethyl benzoyl phenyl ethyl phosphonate through the steps of carrying out substitution condensation reaction on dichlorophenyl phosphine and ethanol to obtain an intermediate; performing condensation reaction on the intermediate and 2,4,6-trimethyl benzaldehyde under an alkaline condition, and finally performing oxidation by using an oxidant under catalysis of a catalyst. The preparation process of 2,4,6-trimethyl benzoyl phenyl ethyl phosphonate, disclosed by the invention, has the advantages as follows: the influences of an acidic medium on the intermediate can be avoided; the requirements of the condensation reaction between 2,4,6-trimethyl benzaldehyde and phenyl ethyl hypophosphite for reaction equipment can be reduced; meanwhile, the reaction yield can be ensured; the preparation process is simple in operation and is suitable for industrial production.

The invention relates to a Pirarubicin sustained-release implant for treating a solid tumor, which is characterized in that: the sustained-release implant contains an effective anticancer amount of Pirarubicin and sustained-release excipients and a certain amount of sustained-release regulator. The solid tumors include the esophageal canner, the gastric canner, the breast canner, the ovarian canner, the prostate canner, the bladder canner, the liver canner, the lung canner, and the rectum canner. The sustained-release excipients are mainly a copolymer of glycollic acid and hydroxyacetic acid and one of the two materials, polifeprosan and poly-(L-lactide-co-ethyl phosphonate), or a combination of the two materials, in the process of degradation and absorption of which the Pirarubicin is sustainedly released to part of the tumor, thus the entire toxicity of the Pirarubicin is significantly reduced while an effective medicine consistency is maintained on part of the tumor. That the sustained-release implant is implanted inside part of the tumor can not only reduce the entire toxicity of the Pirarubicin but also enhance the medicine consistency on part of the tumor, thereby increasing the curing effect of non-operative therapeutics such as chemotherapeutic drugs and radiotherapy.

The invention provides a combustible cartridge case/box slurry formula and a preparation method of a combustible cartridge case/box. The formula comprises 100 parts of acrylic resin, 1-4 parts of a photoinitiator, 40-100 parts of a reactive diluent and 100-246 parts of explosive crystals, wherein the explosive crystals are one or a mixture of 1, 3, 5-trinitro-1, 3, 5-triazacyclohexane and 1, 3, 5, 7-tetranitro-1, 3, 5, 7-tetraazacyclooctane, the acrylic resin is epoxy acrylic resin, polyurethane acrylic resin or a mixture of the epoxy acrylic resin and the polyurethane acrylic resin, the photoinitiator is one or a mixture of 2, 4, 6-trimethylbenzoyl phenyl phosphonic acid ethyl ester and 4, 6-trimethylbenzoyl-diphenyl phosphine oxide, and the reactive diluent is one or a mixture of 2-(2-ethyoxyl ethyoxyl) ethyl acrylate and trimethylolpropane triacrylate. The formula provided by the invention can be used for 3D printing preparation. The powder force of the prepared combustible cartridge case/box reaches 845 J/g, the 5s explosion point is 356.6 DEG C, the spontaneous combustion resistance temperature at the temperature of 245 DEG C is larger than 300 s, and the hygroscopicity under the conditions that the temperature is 25 DEG C and the relative humidity is 89% is 0.5%.

The invention relates to the field of photocuring functional new material chemicals, and discloses a high performance liquid phase streamline type continuous automatic production technology of an acylphosphine oxide organic phosphine compound for the first time, which not only can produce a single specific target product, but also can co-produce a product mixture of two or more than two of the products of the type. The process technology has outstanding low-cost economic competitiveness and environment-friendly characteristics for large-scale manufacturing of target products. The target product comprises sym-trimethylbenzoyl diphenyl phosphine oxide (also known as 2, 4, 6-trimethylbenzoyl diphenyl phosphine oxide, trade name TPO), sym-trimethylbenzoyl phenyl ethyl phosphonate (trade name TPO-L) and structural analogues thereof, and a mixture of the sym-trimethylbenzoyl diphenyl phosphine oxide and the sym-trimethylbenzoyl phenyl ethyl phosphonate. The organic phosphine compound is an olefinic bond-containing (C=C) unsaturated radiation polymerization system photoinitiator and/or flame retardant and the like with wide application.

The invention relates to a Sorafenib sustained-release implant for treating a solid tumor, which is characterized in that: the sustained-release implant contains an effective anticancer amount of Sorafenib and sustained-release excipients and a certain amount of sustained-release regulators. The solid tumors comprise the esophageal canner, the gastric canner, the breast canner, the ovarian canner, the prostate canner, the bladder canner, the liver canner, the lung canner, and the rectum canner. The sustained-release excipients are mainly a copolymer of glycollic acid and hydroxyacetic acid and one of the two materials, polifeprosan and poly-(L-lactide-co-ethyl phosphonate), or a combination of the two materials, in the process of the degradation and absorption of which the Sorafenib is continuously released to part of the tumor, thus the entire toxicity of the Sorafenib is significantly reduced while an effective medicine consistency is maintained on part of the tumor. That the sustained-release implant is implanted inside part of the tumor can not only reduce the entire toxicity of the Sorafenib but also enhance the medicine consistency on part of the tumor, thereby increasing the curing effect of non-operative therapeutics such as chemotherapeutic drugs and radiotherapy.

The invention discloses a method for synthesizing alpha-aryl ethyl phosphonate.The method comprises the following steps that alpha-aryl vinyl phosphonate, potassium phosphate and o-nitro-benzenesulfonyl hydrazide are added into a reactor; after vacuumizing is conducted, N2 is introduced to remove oxygen; under the protection of N2, anhydrous acetonitrile is added, and stirring is conducted for 5-10 h at room temperature; after the reaction is finished, water is added into a reaction mixture for dilution, extraction is conducted with ethyl acetate, drying is conducted with sodium sulphate anhydrous, mixed liquor of petroleum ether and ethyl acetate serves as eluent, column chromatography isolation is conducted, distillation is conducted finally, and alpha-aryl ethyl phosphonate is obtained.According to the method for synthesizing alpha-aryl ethyl phosphonate, transition metal does not participate, the substrate universality is good, the compatibility of a functional group is high, the reaction condition is mild, the reaction efficiency is high, and operation is safe, easy and convenient.

The invention discloses a production method for a medicine for preventing and treating verticillium dahliae. The production method comprises the following steps: A preparing materials including 50% copper(succinate+glutarate+adipate), 60% aluminum tris(-O-ethyl phosphonate), 86.2% cuprous oxide wettable powder, artemisinin, pulsatilla chinensis saponin, glycyrrhizic acid, Shuanghuanglian and pericarpium citri reticulatae; B carrying out alcohol digestion on an extracting solution of the Shuanghuanglian and the pericarpium citri reticulatae; C compounding the 50% copper(succinate+glutarate+adipate), the 60% aluminum tris(-O-ethyl phosphonate), the 86.2% cuprous oxide wettable powder, the artemisinin, the pulsatilla chinensis saponin and the glycyrrhizic acid with the extracting solution obtained in the step B; and agitating uniformly and carrying out ultraviolet sterilization to obtain the medicine for preventing and treating the verticillium dahliae. The production method is simple and the produced medicine is easy in proportioning and convenient to use, and has the good effect of treating eggplant verticillium; tests prove that a 400-600-time diluting solution of the mixture has an obvious inactivation effect on te fungi imperfecti verticillium dahliae and the sterilizing effect is good.

The invention discloses a preparation method of a functionalized magnetic adsorption material, and the method is characterized by comprising the following steps: adding ethyl 2, 5-dihydroxy-1, 4-benzene diphosphonate and/or diethyl 2, 5-dihydroxyphenyl phosphonate into a solvent A, adding nano ferroferric oxide, and reacting at a certain temperature to obtain a reacted material; cooling the reacted material, performing filtering and separating, washing the solid with a solvent B, and performing drying to obtain the functionalized magnetic adsorption material. The functionalized magnetic adsorption material prepared by the invention is of a porous structure, is formed by sparsely stacking spherical particles, and has rich functional groups such as hydroxyl groups and phosphorus oxygen groups; the functionalized magnetic adsorption material prepared by the method has the advantages of simplicity in synthesis, low cost, good selectivity, large adsorption capacity, convenience in collection after adsorption and the like, can be actually used for adsorbing, enriching or removing uranium in an aqueous solution, and is high in practicability.

The invention relates to a preparation method of methyl propanal ethyl phosphonate as a glufosinate-ammonium intermediate and belongs to the field of organic chemistry. The preparation method comprises the following steps: (1) taking 3,3-diethoxy propyl methyl ethyl phosphonate as a raw material, catalyzing and hydrolyzing via a catalyst to prepare methyl propanal ethyl phosphonate, wherein the catalyst is sulfonic acid resin, strong acid ion exchange resin or perfluorinated sulfonic acid resin; and (2) filtering the product obtained in the step (1) for recycling sulfonic acid resin, and carrying out pressure-reduced desolvation of filtrate to obtain methyl propanal ethyl phosphonate. The specific preparation method is as shown in the description. According to the preparation method of methyl propanal ethyl phosphonate as the glufosinate-ammonium intermediate, through optimization of the catalyst, the reaction time is greatly reduced; the yield is improved; meanwhile, the catalyst is easy to recycle and is reusable; the production cost is reduced.

The invention discloses an efficient thick copper plate solder resist printing method. Ink adopted in the high-efficiency thick copper plate solder resist printing method mainly comprises the following raw materials by mass: 3, 4-epoxy cyclohexyl methyl methacrylate, amido resin, titanium dioxide, 3-methacryloyloxy propyl trimethoxy silane, propylene glycol methyl ether acetate and 2, 4, 6-trimethylbenzoyl phenyl ethyl phosphonate, and all the substances interact with one another, so that the ink can be used for preparing the high-efficiency thick copper plate solder resist printing ink. The ink has the advantages of favorable curing property, favorable adhesive force, excellent heat resistance, excellent weather resistance and high curing speed.