High performance liquid phase continuous automatic production and co-production technology of organic phosphine compound

Abstract

The invention relates to the field of photocuring functional new material chemicals, and discloses a high performance liquid phase streamline type continuous automatic production technology of an acylphosphine oxide organic phosphine compound for the first time, which not only can produce a single specific target product, but also can co-produce a product mixture of two or more than two of the products of the type. The process technology has outstanding low-cost economic competitiveness and environment-friendly characteristics for large-scale manufacturing of target products. The target product comprises sym-trimethylbenzoyl diphenyl phosphine oxide (also known as 2, 4, 6-trimethylbenzoyl diphenyl phosphine oxide, trade name TPO), sym-trimethylbenzoyl phenyl ethyl phosphonate (trade name TPO-L) and structural analogues thereof, and a mixture of the sym-trimethylbenzoyl diphenyl phosphine oxide and the sym-trimethylbenzoyl phenyl ethyl phosphonate. The organic phosphine compound is an olefinic bond-containing (C=C) unsaturated radiation polymerization system photoinitiator and / or flame retardant and the like with wide application.

Description

[Technical field][0001]The present invention relates to the field of new material chemicals in photocurable function, and a high-performance liquid phase flow line continuous automation production technology of a kind of acylphophosphine oxide organic phosphine compound is disclosed, which can produce a single-specific target product. The type of product mixture of two or more of the two or more. The process technology has highlighted low-cost economic competitiveness and environmentally friendly characteristics for large-scale manufacturing of target products. The target product includes average trimethylbenzoyl diphenyl oxide (also known as "2,4,6-trimethylbenzoyl diphenyl phosphine", trade name TPO) and average trimethylbenzene Formylphenylphosphonic acid ethyl ester (trade name TPO-L) and its structural analogs, and mixtures thereof. This type of organic phosphine compound is a widely used hydroken bond (C = C) unsaturated radiation polymerization system photosensitive initiator...

AI Technical Summary

Problems solved by technology

[0004] The above-mentioned known literature technologies have been proved to have significant process defects one by one, including but not limited to the following aspects: the use of phosphorus trichloride, benzene, aluminum trichloride and other hazardous raw materials, high cost of process routes, and many environmentally hazardous wastes, The use of highly air-sensitive and thus expensive and hazardous alkali metal or organometallic reagents; the use of highly air-sensitive and foul-smelling organophosphonane raw materials or intermediates; the use of highly polluting main group metal and / or transition metal oxidation catalysts, Accelerators, or decomplexers (patents CN201310099065 and CN2011104264185), etc.; use of inorganic or organic peroxides with explosion risks as terminal oxidants or accelerators, and / or process emissions of hazardous chemicals

[0005] A special focus of attention of the above-mentioned known document technology is that a large amount of solid reaction raw materials and solid reaction catalyst and / or promotor and / or decomplexer etc. have to be involved in single or multi-step in its distribution synthetic technique, simultaneously It will inevitably lead to the generation of a large amount of solid waste. The known technology in the past half a century has always been the production practice of intermittently synthesizing a single specific target product with high pollution and low efficiency, and has never achieved its high efficiency. Liquid-phase streamlined continuous automated production, not to mention the co-production of the above compounds

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