4 results about "Newborn infant" patented technology

An adhesive skin dressing kit for securing a medical device to a newborn infant includes a pair of storage sheets each comprised of an adhesive resistant material. A plurality of first adhesive pads is each removably adhered to the adhesive resistant material of a respective one of the pair of storage sheets. A plurality of second adhesive pads is each of the plurality of second adhesive pads is removably adhered to the adhesive resistant material of a respective one of the pair of storage sheets. Each of the plurality of second adhesive pads and first adhesive pads has dimensions sufficiently small to enable the each of the plurality of second adhesive pads to be positionable over a respective one of the plurality of first adhesive pads on the newborn infant's face for securing a medical device between the first adhesive pad and the second adhesive pad.

In this invention, the inventors report the characterization of BCLA (brain cyst-loaded antigen), a protein uniquely expressed in the merozoite stage of a parasite. In cysts directly purified from mouse brain, the protein is distributed both internally and on the surface of the cyst. ELISA antibody capture using a combination of serologically reactive BCLA peptide and recombinantly expressed C-terminal domain (rBCLA) constitutes an effective serological marker of latent infection with high sensitivity, definitively and uniquely correlated with the presence of cysts in mouse brain. Antibodies against the BCLA antigen have been detected in human patients. Enrichment titers were detected in patients identified as seropositive for Sag1 or tachyzoite-associated antigen. Further correlation between anti-BCLA IgG synthesis and cysts in humans was demonstrated by significantly stronger recorded titers in the pathology group strongly correlated with the presence of cysts. Furthermore, newborns with confirmed congenital toxoplasmosis showed significantly higher levels of anti-BCLA IgG at birth compared to their mothers, indicating specific intrauterine synthesis of this IgG. Therefore, this invention relates to a novel Toxoplasma gondii protein, hereinafter referred to as BCLA, which is a novel serological marker whose expression is limited to latent toxoplasmosis (schizonts / cysts). This specific protein and its antigenic fragments can be used to detect autoantibodies in patient serum for the diagnosis of latent toxoplasmosis. This invention also relates to derived antibodies that specifically bind to this novel protein, generated through immunization with BCLA.

This utility model discloses a shock-absorbing support for a transport incubator, specifically a shock-absorbing support for placement inside a transport incubator. It includes an injection-molded mattress support and a base plate. The adjacent surfaces of the injection-molded mattress support and the base plate are symmetrically equipped with adapter seats distributed along a pair of opposite corners, with the two opposite corners being different. It also includes a buffer damping module, which, according to its structure, consists of a first hinge rod and a second hinge rod. The end face of the first hinge rod has a guide rod that is slidably fitted into a bore at the end of the second hinge rod. A first equidistant spring is fixedly installed between the first and second hinge rods, sleeved on the outside of the guide rod. The first and second hinge rods are respectively hinged to adapter seats on the same side. This utility model adds a mattress support with vertical cushioning capacity inside the incubator, thereby minimizing the impact of vibration on newborn infants.