13 results about "Soya lecithin" patented technology

The invention discloses a drug-loaded protein-phospholipid composite nanoparticle as well as a preparation method and application thereof. The drug-loaded protein-phospholipid composite nanoparticle has a core-shell structure, an inner core comprises silk fibroin and a hydrophilic drug, a shell layer comprises a plurality of phospholipid bimolecular layers which are stacked layer by layer, each phospholipid bimolecular layer comprises soya bean lecithin, a hydrophobic drug is embedded in a hydrophobic region in each phospholipid bimolecular layer, and the hydrophobic drug is embedded in a hydrophobic region in each phospholipid bimolecular layer. Silk fibroin and a hydrophilic drug are embedded in the hydrophilic area, and zein and cholesterol are embedded in the phospholipid bilayer. The drug-loaded protein-phospholipid composite nanoparticle can simultaneously embed a hydrophobic drug and a hydrophilic drug, has the advantages of large drug loading capacity, high bioavailability, good stability, good transdermal permeation effect and the like, has wide application prospects in the fields of transdermal drug delivery preparations and skin care products, and is simple in preparation method, mild in reaction condition and suitable for industrial production. The method is suitable for large-scale industrial production and application.

The invention belongs to the technical field of nanotechnology, and particularly discloses a preparation method and application of iron-containing lipid nanoparticles IO-LNPs with an antibacterial function. The iron-containing lipid nanoparticles (IO-LNPs) with an antibacterial function are synthesized by taking iron oleate, soya bean lecithin and DSPE-MPEG2000 as raw materials through a gradient solvent diffusion method, can induce a bacterial ferroptosis effect, has good antibacterial activity, can effectively kill gram positive (S.aureus) and negative (E.coli) bacterial strains, and has good biological membrane prevention and destruction capabilities on S.aureus and E.coli. The iron-containing lipid nanoparticles (IO-LNPs) have the advantages that the iron-containing lipid nanoparticles (IO-LNPs) with the antibacterial function can be used for preparing the iron-containing lipid nanoparticles (IO-LNPs), and the iron-containing lipid nanoparticles (IO-LNPs) can be used for preparing the iron-containing lipid nanoparticles (IO-LNPs); the iron-containing lipid nanoparticles IO-LNPs with the antibacterial function, prepared by the preparation method disclosed by the invention, show relatively high stability and biocompatibility under physiological conditions, have an excellent effect in antibacterial performance and are a safe and efficient medicament for resisting bacterial infection and promoting wound healing.

The invention belongs to the technical field of biological medicine and medical beauty, and particularly relates to stem cell supernatant liposome as well as a preparation method, an encapsulation efficiency detection method and application thereof. The preparation method of the stem cell supernatant liposome comprises the following steps: culturing spermatogonial stem cells, and collecting spermatogonial stem cell supernatant; dissolving sitosterol and soya bean lecithin by using an organic solvent to form an organic phase; and mixing the spermatogonial stem cell supernatant with the organic phase by adopting a solvent injection method, a film dispersion method or a reverse evaporation method to obtain the stem cell supernatant liposome. According to the stem cell supernatant liposome preparation method provided by the invention, the stem cell supernatant liposome with high encapsulation efficiency and stable structure can be prepared, and due to the double-layer protection effect of lipid, the degradation degree of protein drugs can be reduced, so that the effect of improving the relative stability of active substances of the protein drugs is achieved.

The invention belongs to the technical field of semen cryopreservation, and particularly relates to a sheep semen cryopreservation solution and a semen preservation method. The sheep semen freezing medium comprises the following components: Tris, citric acid, fructose, lactose, trehalose, penicillin, streptomycin, soya bean lecithin, nobiletin, glycerol and water. The nobiletin with a specific content is used as an effective antioxidant component of the sheep sperm cryopreservation agent, so that the nobiletin plays an antioxidant role when the sperms are frozen, and the sperms are more stable in the cryopreservation process. After nobiletin is added, the activity and movement performance of frozen and unfrozen sheep sperms can be remarkably improved. The oxidative stress injury of the sperms in the freezing process is effectively reduced, and the oxidation resistance of the sperms is improved.

The invention discloses a permeation enhancing composition as well as a preparation method and application thereof, and belongs to the technical field of cosmetics, the permeation enhancing composition comprises the following components in parts by mass: 0.5-8 parts of hydrolyzed sodium hyaluronate, 5-20 parts of a stabilizer, 12-25 parts of saccharomycetes / rice fermentation product filtrate and 40-80 parts of a solvent; the stabilizer is prepared from decapeptide-4, soya bean lecithin, sodium carboxymethyl cellulose and a polyethylene glycol surfactant according to the mass ratio of (0.05 to 0.4) to (0.05 to 0.4) to (0.08 to 0.5) to 1. Under the combined action of the hydrolyzed sodium hyaluronate, the stabilizer and the saccharomycetes / rice fermentation product filtrate, the surface tension is effectively reduced, the permeability and wettability of liquid are improved, the permeability of cell membranes is destroyed, and the anti-oxidation effect and stability of the composition are improved, the skin barrier is repaired, and the moisturizing effect and skin elasticity of the composition are improved. On the basis of not destroying the skin barrier, effective components are promoted to permeate into the deep layer of the skin, the effective components are mildly released, and effective absorption of the skin is promoted.

The invention discloses a Spartina alterniflora drug control technology, and relates to the technical field of coastal wetland ecological management, the early stage of bud differentiation of Spartina alterniflora is monitored through dynamic opportunity selection, and the soil salinity is adjusted by selecting a time window 2 hours after ebb tide and with a sunny day probability greater than 80% in combination with tide forecast. The method comprises the following steps: preparing a composite synergistic agent containing 25% imazapyr, soya bean lecithin, sodium humate and other materials, uniformly spraying the composite synergistic agent to leaf surface and root soil of plants by adopting high-pressure atomization equipment after ebb tide, supplementing an agent containing double nano titanium dioxide in case of rainfall, and reducing environmental interference and improving agent absorption efficiency through tide synergy and salinity adjustment; the adhesive force and the durability are enhanced through the synergistic effect of all the components in the composite agent; high-pressure atomization is combined with a calculation model to ensure uniform deposition of liquid medicine at the rhizome junction; the cloudy and rainy emergency mechanism dynamically responds to sudden weather, and the control continuity is maintained, so that the overall control effect, the resource utilization rate and the environmental adaptability are improved.

The invention provides a quercetin-phospholipid complex and a preparation method thereof, the quercetin-phospholipid complex is composed of quercetin and soya bean lecithin, the mass percentage of the quercetin is 10%-40%, and the mass percentage of the soya bean lecithin is 60%-90%. The water solubility and fat solubility of the quercetin-phospholipid complex prepared by the method are higher than those of free quercetin, the in-vitro oxidation resistance of the quercetin-phospholipid complex is equivalent to that of the free quercetin, the oxidation resistance stability of edible oil and fat can be obviously improved, and the storage life of the oil and fat is prolonged.

The invention discloses a flotation separation collecting agent for associated ultrafine particle apatite in vanadium titano-magnetite and a preparation method and a direct flotation process of the flotation separation collecting agent, and relates to the technical field of mineral separation. The flotation separation collecting agent comprises oxidized paraffin soap, salicylhydroxamic acid, soya bean lecithin and dodecyl sulfopropyl betaine. The preparation method comprises the following steps: independently dissolving the components, and sequentially mixing. The flotation separation collecting agent for the superfine apatite has the characteristic of synergistic interaction of multiple agents, the agent cost is low, the collecting capacity and the separation selectivity of the collecting agent for the superfine apatite are remarkably improved, the phosphorus resource recovery rate exceeds 80%, the loss of the phosphorus resource in tailings is effectively reduced, and the flotation separation collecting agent for the superfine apatite is suitable for industrial production. And efficient recycling of Panxi vanadium titano-magnetite associated phosphorus resources is achieved.

The invention discloses chewing gum based on composite stimulation as well as a preparation method and application of the chewing gum. Comprising the following raw material components in parts by weight: 0.09 to 0.105 part of 1, 8-cineole, 40 to 45 parts of gum base, 25 to 35 parts of D-mannitol, 8 to 15 parts of erythritol, 12 to 18 parts of purified water, 1 to 2 parts of caprylic / capric triglyceride, 0.3 to 0.8 part of soya bean lecithin, 0.2 to 0.4 part of Arabic gum and 0.05 to 0.1 part of carnauba wax. By organically combining composite stimulation with computerized task training, the limitation that a traditional nerve stimulation technology needs professionals and equipment is avoided, and work memory training is safe, effective and easy and convenient to operate. The device is especially suitable for daily training of people needing cognition improvement, such as people with high mental load and people with hypomnesis.

The invention provides a curcumin preparation and a preparation method thereof. The preparation method comprises the following steps: stirring and mixing whey protein and water; adding a NaOH solution into the system, and stirring and mixing; adding zein into the system, and continuously stirring; adding curcumin, propylene sulfide and soya bean lecithin into the system, stirring and mixing, and adjusting the pH value to 6.5; adding mannitol into the system, stirring until the mannitol is dissolved, and then performing vacuum freeze drying to obtain a dry sample; and mixing with auxiliary materials to obtain the curcumin preparation. The powdery curcumin preparation is prepared through a protein encapsulation method, soybean lecithin is added in the protein encapsulation process, the encapsulation efficiency can reach 92.35%, the particle size of effective components is smaller than 100 nm, particle size distribution is concentrated, the water solubility of curcumin is improved, and the bioavailability of curcumin is improved; a small amount of propylene sulfide is added in the curcumin encapsulation process, and it is found that due to addition of propylene sulfide, curcumin and propylene sulfide generate a synergistic effect, and the anti-inflammatory effect of the preparation is promoted.

The invention relates to a fat burning and weight losing diglyceride composition and a preparation method thereof. The diglyceride microcapsule powder prepared from the resistant dextrin, the compound vitamins, the mono / diglyceride fatty acid esters, the alginate oligosaccharides, the soya bean lecithin, the coconut oil, the diglyceride and the like has the effects of maintaining the blood fat level, reducing the accumulation of intake fat and enhancing the prevention effect on fat accumulation, is beneficial to body weight control, and meanwhile, can be used for improving the body weight. By adding the corn starch, the purple sweet potato powder, the oat powder, the Chinese yam powder, the brown rice powder and the like, the effect of supplementing nutrition can be effectively achieved, the satiety can be brought to eaters, and therefore the requirement for eating high-calorie food is reduced, and the weight losing and fat reducing effects are guaranteed. The preparation method of the product is simple, the metabolic capability of eaters can be obviously improved, so that fat is consumed, and the product has obvious fat-reducing and weight-losing effects and is beneficial to the body health of users.