89 results about "Targeted screening" patented technology

The application discloses a kind of unsupervised time series anomaly detection methods, the method includes obtaining historical time series data, according to the correlation of historical time series data and target screening characteristic variable, according to characteristic variable constructs instance anomaly detection task historical time series data;To instance anomaly detection task historical time series data relevant field adopts rolling statistical characteristic strategy, constructs instance anomaly detection task historical time series data model;Instance anomaly detection task historical time series data model is input into self-encoding framework after batch processing, after three times coding, three times decoding obtains reconstructed instance anomaly detection task historical time series data module;Instance anomaly detection task historical time series data module is compared and analyzed with reconstructed instance anomaly detection task historical time series data module, obtains loss time series dataset;Decision tree model is constructed, and each sample of loss time series dataset is scored, and final anomaly detection result is obtained according to score.The application can improve the ability and efficiency of time series data anomaly identification.

The application discloses a combine harvester with a material differentiation processing function, which comprises a walking chassis, a ploughing and harvesting assembly, a material conveying assembly and a threshing and cleaning assembly arranged in sequence from front to back on the walking chassis; the threshing and cleaning assembly comprises a threshing device and a cleaning device arranged in an up-down mode; the cleaning device comprises a sieve body and a driving main shaft for vibrating the sieve body; the number of the sieve bodies is at least three, and all the sieve bodies are closely arranged in the axial direction of the driving main shaft; a driving member is connected between the driving main shaft and each sieve body, and the specifications of the driving members connected with the sieve bodies at different positions are different, so that the vibration parameters of the sieve bodies at different positions are different. In the application, the structural design of the cleaning device can fully meet the distribution characteristics that the materials falling from the threshing cylinder of the threshing device are more on both sides and less in the middle, and targeted screening processing of the differentially distributed materials is realized.

A method for screen projection in vehicle includes displaying first screen projection data sent from connected first mobile terminals in sub-areas on a display screen; in response to receiving a connection request from a second mobile terminal, establishing a connection with the second mobile terminal; receiving second screen projection data sent from the second mobile terminal; determining whether any target screen projection data having a same data type as the second screen projection data exists in the first screen projection data; in response to the target screen projection data being determined, assigning a target sub-area corresponding to the target screen projection data to the second mobile terminal to project the second screen projection data sent from the second mobile terminal; and in response to no target screen projection data being determined, adding a new sub-area on the display screen to screen project the second screen projection data.

The invention provides a method for high-throughput screening of an alpha-glucosidase inhibitor from boxthorn leaves based on a multi-shell MOF immobilized enzyme, and aims to overcome the bottlenecks of low throughput, tedious operation, high cost and the like of a traditional screening method. The core process of the method comprises the following steps: preparing a boxthorn leaf sample solution and pre-evaluating the in-vitro alpha-glucosidase inhibitory activity; a multi-shell MOF immobilized enzyme technology is coupled with a UPLC-QTOF-MS / MS technology, so that targeted screening, efficient separation and accurate identification of active components are realized; verifying the alpha-glucosidase inhibitory activity of the target compound; and predicting the binding site of the small molecule compound and the enzyme through a molecular docking technology. The method has the core advantages of high specificity, high sensitivity, high flux, repeated utilization of enzyme receptors and the like by depending on the inherent characteristics of an immobilized enzyme technology, can synchronously screen and identify various inhibitors, effectively integrates the resource advantages of a boxthorn leaf natural product and the high efficiency of a modern high-flux screening technology, and has a wide application prospect. And a key technical support is provided for diversified development of diabetes treatment medicines.

The application discloses a financial data display method and device, a storage medium and an electronic device, and relates to the technical field of artificial intelligence. The method comprises the following steps: acquiring N pieces of financial data to be displayed on a target screen, wherein N is a positive integer greater than 1; acquiring first portrait information of a first object, wherein the first object is an object to be used with the N pieces of financial data, and the first portrait information at least comprises attribute information of the first object and preference information of the first object for a screen layout; inputting the first portrait information into a target decision tree model for classification processing, and outputting a screen layout recommended for the first object; and displaying the N pieces of financial data on the target screen based on the screen layout. Through the application, the problem that, in the related art, when financial data is displayed on a screen, the screen cannot preferentially display data information that a user is interested in, and the effect of using the financial data displayed on the screen is poor, is solved.

The invention provides a transient alarm tracking method and device, terminal equipment and a storage medium, and the method comprises the steps: firstly obtaining an image of a target screen on to-be-tracked equipment; then determining a preset alarm information display area corresponding to the target screen, and performing character recognition on the preset alarm information display area to obtain a character recognition result; and finally, matching the character recognition result with a preset alarm character library, and determining that the to-be-tracked device has a transient alarm under the condition of successful matching. Therefore, the characters in the specific area of the screen of the to-be-tracked equipment are automatically obtained and recognized in a non-intrusive mode, so that the preset alarm information is accurately matched, millisecond-level response is achieved, transient faults which cannot be traced in a traditional mode are effectively captured and recorded, and the accuracy and reliability of equipment diagnosis are improved.

Provided are a centromere protein CENP-M small molecule inhibitor cenpemlin, and a preparation method therefor and the use thereof. A small molecule compound cenpemlin is obtained by means of analyzing the protein plane information of the fine structures of CENP-M and CENP-L and performing targeted screening. The results of biochemical and cytological experiments all indicate that cenpemlin inhibits the proliferation of cancer cells by means of interfering with the interaction between CENP-M and CENP-L, thereby providing a new compound for analyzing and interfering with the rapid proliferation of cancer cells.

The present application relates to plant RL1 gene regulation broad spectrum disease resistance and application. The present application provides a RL1 down-regulation agent for use in improving plant disease resistance, or for preparing a preparation for enhancing plant disease resistance. The present application also provides a method for improving traits of a plant in the family Poaceae or preparing a plant in the family Poaceae with improved traits, comprising: down-regulating the expression or activity of RL1 in the plant; the improved traits include: improving the disease resistance of the plant. The present application also provides the use of RL1 as a molecular marker for identifying plant disease resistance, or as a molecular marker for targeted screening of plants with disease resistance, and related identification methods, screening methods, etc.

The invention discloses a satellite-borne SAR (Synthetic Aperture Radar) self-focusing method and system for a long-time integral bunching mode, a computer and a storage medium, and the method comprises the steps: screening a strong scattering target region in a manner of taking the maximum contrast or maximum power as a target according to the size of a divided grid; a minimum entropy distance alignment algorithm based on a partial frequency spectrum is used to realize distance migration error estimation of a partial region, a mode of combining hamp filtering and polynomial fitting is used to realize full-scene distance migration error estimation, and a minimum entropy phase correction algorithm is used to realize phase error estimation of a partial region. All-scene phase error estimation is realized by combining a Savitzky-Golay filter and a polynomial fitting mode, and unified compensation processing is performed on an original all-scene image by applying all-scene range migration errors and a phase error estimation result, so that all-scene fine focusing is realized. According to the invention, large-scene full-image fine focusing under the condition of over 15 seconds of ultra-long synthetic aperture time can be realized.

The present application belongs to the technical field of equipment control, and particularly relates to a high-efficiency environment-friendly sand and gravel screening equipment control system, to solve the technical problem that the existing method lacks deep understanding and accurate prediction of the internal mechanism of the screening process, and cannot realize the collaborative optimization of multiple key performance indicators such as screening efficiency, hole blocking risk and operation energy consumption. It comprises: a calculation module, which predicts the evolution trend of the hole blocking probability of the screen surface and calculates the transition energy consumption of the particles; a construction module, which constructs a weighted multi-objective optimization function; and a regulation and control module, which is used for real-time regulation and control of the screen parameters of the screening equipment according to the obtained target screen parameter combination. The present application ensures that the particle size distribution of the environment-friendly sand and gravel is highly stable and continuously meets the engineering standards, and improves the product qualification rate.

The invention discloses a non-targeted screening method for pesticide and veterinary drug residues in raw milk based on LC-TOFMS (liquid chromatography-time of flight mass spectrometry) and application of the non-targeted screening method, and belongs to the technical field of food safety detection. According to the method, a QuEChERS technology is adopted to carry out pretreatment on a raw milk sample, a liquid chromatography-time-of-flight mass spectrometry technology is utilized to carry out detection, and a self-built mass spectrometry database is combined to realize non-targeted qualitative screening. A self-established mass spectrum database comprises precise mass numbers, retention time, parent ion loading modes and secondary mass spectrum fragment information of 46 kinds of pesticides and 54 kinds of veterinary drugs. The method is simple in pretreatment, high in detection speed, wide in coverage range and suitable for rapid screening and quality monitoring of pesticide and veterinary drug residues in raw milk, and has good practicability and popularization value.

The invention provides an automatic reconstruction method and system for a connection relation in a secondary circuit digital model, and the method comprises the steps: extracting semi-connection cable information containing a descriptive text of an opposite-side screen cabinet from the secondary circuit digital model, and carrying out the semantic analysis of the semi-connection cable information, so as to extract the screen cabinet feature information corresponding to each screen cabinet; performing one-to-one matching on the source screen cabinet and all the target screen cabinets according to the screen cabinet feature information, and establishing a screen cabinet level connection relationship for the source screen cabinet and the target screen cabinet which are successfully matched; pairing the semi-connection cables between the source screen cabinet and the target screen cabinet forming the screen cabinet-level connection relation according to a preset multi-level cable matching rule; and performing attribute complementation on the successfully paired semi-connection cables to form a complete cable connection record, and persisting the complete cable connection record to the secondary loop digital model. According to the method, high automation, high accuracy and high robustness of connection relation reconstruction can be realized.

The invention provides a mass spectrum full-scanning mode-based qualitative and semi-quantitative integrated analysis method for environmental trace micro-pollutants, which comprises the following steps of: analyzing precursor ions without MS / MS secondary mass spectrum in a full-scanning MS mass spectrum, and forming a characteristic table by using data of the precursor ions, reserving candidate compounds corresponding to the precursor ions with high matching degree to generate a first candidate library; searching data of fragment ions with collision energy less than or equal to 20 eV corresponding to the candidate compound in an open source library, integrating the data of the fragment ions and the data of precursor ions in the first candidate library to construct a targeted screening library, performing targeted retrieval in a full-scanning MS mass spectrum, and then performing confidence evaluation and semi-quantitative analysis. According to the method, a large number of lost low-abundance fragment ions can be retrieved, trace micropollutants can be effectively identified, the lowest detection concentration can reach 0.5 ppt level or below, and the method has high confidence coefficient.

The invention discloses a fungaltoxin non-targeted screening mass spectrum data processing method based on deep learning, and relates to the technical field of food-borne toxin detection.The fungaltoxin non-targeted screening mass spectrum data processing method comprises the steps that on the basis of a standardized peak list, ion peaks serve as nodes, the mass spectrometry relation between the ion peaks serves as edges, and a mass spectrum structure is constructed; based on a connection relationship between nodes in the mass spectrum structure, identifying different mass spectrum relationship types, constructing different meta-paths from a starting ion peak to an ending ion peak, and generating a graph-level feature vector representing the whole mass spectrum structure; and performing multi-scale wavelet transform on the graph-level feature vector, obtaining a correction distance matrix by combining the distribution density value of the known mycotoxin category in the feature space, and extracting a multi-scale distance component corresponding to each known mycotoxin category for weighted fusion to obtain a minimum attribution distance. According to the method, deep semantic modeling of complex mass spectrum data is realized, so that the recognition accuracy of known toxins and the structural interpretability of unknown toxins are greatly improved.

The invention discloses a high-polysaccharide dendrobium officinale variety germination period directional screening cultivation method, and belongs to the technical field of tissue culture. The invention provides a high-polysaccharide dendrobium officinale variety germination period directional screening cultivation method aiming at the problems that existing dendrobium officinale germplasm is mixed and the polysaccharide content is unstable. According to the method, the concentration of a periodate solution adopted for acidolysis treatment is remarkably reduced, the acidolysis time is shortened, a chromogenic reaction is achieved outside the protocorm, the situation that epidermal cells of the protocorm are excessively damaged and a coloring agent enters the protocorm to cause tissue structure change is avoided, and it is guaranteed that the structure of dendrobium officinale is complete and the shape of dendrobium officinale is stable; meanwhile, the dyeing time is shortened, rapid and lossless identification of the dendrobium officinale high-polysaccharide germplasm in the protocorm stage is achieved, the breeding period is remarkably shortened, and the screening accuracy and efficiency are improved. The cultivated high-polysaccharide dendrobium officinale variety shows consistency and stability in the aspects of polysaccharide content and agronomic traits.

The invention provides a water dispersible granule containing a pyroxasulfone and flumioxazin weeding composition. The water dispersible granule comprises pyroxasulfone, flumioxazin, a dispersing agent, a wetting agent, a disintegrating agent, an adhesive and filler. According to the invention, by selecting the proper dispersing agent and wetting agent as well as the combination and compatibility of the dispersing agent and wetting agent, performing targeted screening on the dosage of the dispersing agent and wetting agent, and supplementing other auxiliaries, the water dispersible granules with excellent preparation performance indexes such as high activity component content, suspension rate, disintegration property and the like can be obtained, and rapid disintegration (less than or equal to 60 seconds) and high suspension rate (more than or equal to 90 percent) are realized. The invention also relates to a preparation method and application of the water dispersible granule.

An incoming call prompting method includes an electronic device that receives a call request from a contact, and when a flexible screen of the electronic device is in a folded state, the electronic device determines, in response to the call request, a target screen corresponding to the call request, where the target screen is a first screen or a second screen of the flexible screen; the electronic device displays an answer button on the target screen; and the electronic device displays prompt information of the call request on a non-target screen, where the prompt information prompts a user to answer the current call request using the answer button displayed on the target screen.

The present application relates to the technical field of data analysis, and particularly relates to a veterinary drug residue non-target screening analysis method and system. Veterinary drug residue sample analysis veterinary drug matrix state release behavior characteristic data; the veterinary drug matrix state release behavior characteristic data is monitored to the reliable veterinary drug candidate non-target signal, and the reliable veterinary drug candidate non-target signal data is generated; according to the reliable veterinary drug candidate non-target signal data, candidate non-target signal release stage characteristic analysis is carried out, and candidate non-target signal release stage characteristic data is generated; based on the reliable veterinary drug candidate non-target signal data, candidate non-target compound structure analysis is carried out, and candidate non-target compound structure data is generated; based on candidate non-target signal release stage characteristic data and candidate non-target compound structure data, non-target intelligent screening processing of veterinary drug residue is carried out, and non-target intelligent screening data of veterinary drug residue is generated. The present application realizes non-target comprehensive intelligent screening of veterinary drug residue.

The invention discloses a screen projection display processing method and device, a vehicle and electronic equipment, and relates to the technical field of vehicle screen projection, and the method comprises the steps: obtaining an original frame to be subjected to screen projection in response to a screen projection request, and determining a target region of interest from the original frame to be subjected to screen projection; based on the initial resolution and the target resolution of the target region of interest, image super-division or image enhancement is carried out on the target region of interest to obtain target projection screen display data of the target region of interest, and the target resolution is the resolution of the target region of interest when the target region of interest is displayed at a projection screen receiving end; and displaying the target region of interest on the projection screen receiving end based on the target projection screen display data. According to the method and the device, the projection screen processing efficiency can be improved, and the computing power loss of a vehicle machine is reduced.

The invention belongs to the technical field of biological medicines, and particularly relates to application of NLRC5 in targeted screening of medicines for improving immunotherapy of esophageal squamous carcinoma. NLRC5 expression is inhibited or regulated, and immunotherapy of esophageal squamous cell carcinoma is improved. The NLRC5 is highly methylated, and the expression of the NLRC5 in the ESCC is reduced. The NLRC5 is over-expressed, immune cell infiltration is promoted, meanwhile, immune escape is promoted by intensifying T cell depletion, immune checkpoint expression is up-regulated, and an immunosuppression state is created, so that anti-tumor immune response is potentially weakened. The invention discloses a polyhedral function of the NLRC5 in immune regulation and control from a single cell level, and particularly discloses close association of the NLRC5 with an immune checkpoint pathway and T cell depletion. A theoretical basis is provided for developing a therapy for targeting NLRC5, and a new way is possibly opened up for enhancing anti-tumor immune response. Researches show that NLRC5 is an important regulatory factor of immune response in ESCC, and plays a dual role in immune activation and immunosuppression.

The invention discloses a task execution method and device, equipment, a medium and a product, and belongs to the technical field of computers. The method comprises the steps of obtaining client description information of at least one client, wherein the client description information is used for describing attributes of the client from multiple dimensions; obtaining task information of a first task, wherein the first task is used for indicating execution of operation related to a client program file; based on the client description information and the task information, screening from the at least one client to obtain a first client; and issuing the first task to the first client based on the task information. According to the mode, the server performs targeted screening and issues the first task to the first client, and client program files of only part of clients can be changed.

The invention relates to a display method and device for molecular enumeration, and the method comprises the steps: carrying out the molecular enumeration based on a target frame structure in each molecule obtained through a target reaction type according to a target enumeration mode under the condition that a triggering operation of a first starting control for a target enumeration task is detected, and obtaining an enumeration result; displaying a result interface based on the enumeration result; and under the condition of detecting a trigger operation of a second starting control for a target screening task, screening from all the first molecules according to a target screening condition indicated by the target screening task to obtain a screening result, and updating the result interface based on the screening result. According to the invention, a complex enumeration calculation and screening process can be converted into visual interaction experience, so that a researcher can quickly grasp molecular population characteristics and focus on high-quality candidate compounds.

The invention relates to the technical field of bioengineering and provides a method for improving the specificity and affinity of an aptamer. The method includes: S1, screening a target of an aptamer from a compound information database by virtual computing; S2, verifying the screening result in Step S1 through experiments; S3, performing virtual saturation mutation on a site of the aptamer, and screening out a mutation site of the aptamer; S4, performing base substitution to the mutation site of the aptamer; and S5, detecting the binding parameter of the aptamer after base substitution with the target screened in Step S1, and selecting an aptamer with improved specificity and affinity after base substitution. An efficient molecular design-guided method is developed by computer rational calculation, to improve the specificity and binding affinity of the aptamer by directional modification. The present invention is of great significance for the practical application of aptamers.

The invention discloses deep learning-based deep sea cold spring microbiome antibacterial peptide directional screening and application thereof, and belongs to the technical fields of deep sea extreme environment microbial resource high-value utilization, food preservation and fresh-keeping and bioinformatics. The antibacterial peptide DSCSAMP1-4 applicable to the soy sauce in the high-salt environment is directionally screened by constructing a data set containing polypeptide physicochemical properties, structural characteristics and weighted scores. Wherein the DSCSAMP2-3 containing the alpha-helical structure has obvious growth inhibition on gram-negative bacteria such as escherichia coli and pseudomonas aeruginosa, gram-positive bacteria such as staphylococcus aureus and fungi such as saccharomycetes respectively. The antibacterial peptide is natural, safe, wide in antibacterial spectrum, high in acting efficiency and free of chemical residues, does not affect the flavor of soy sauce, can be prepared into preservative additives of various dosage forms, provides an efficient and environment-friendly preservative solution for the soy sauce industry, promotes high-value utilization of deep sea cold spring microbial resources, and has great industrial popularization value.

This utility model provides a pesticide chemical solid-liquid separation device, relating to the field of pesticide chemical solid-liquid separation technology. It includes a mounting base, a vibrating element disposed on the inner side of the top of the mounting base, a screen frame disposed inside the mounting base for solid-liquid separation of different pesticides, an extrusion element disposed on the inner side of the bottom of the mounting base, and a pressure plate disposed on the outer side of the bottom of the screen frame. The screen frame adopts an inclined structure design, with different sized screen holes on both sides, which not only allows for targeted screening of different materials according to the characteristics of chemical pesticides but also significantly expands the screening area. Simultaneously, by starting a motor to drive the rotating wheel to rotate, the connecting arm further pulls and pushes the screen frame, vibrating and screening the material. As the rotation speed of the rotating wheel increases, the vibration intensity increases, accelerating the solid-liquid separation speed.

This application provides a method, apparatus, and device for adaptive adjustment of an LED screen according to changes in ambient brightness. The method includes: acquiring the ambient brightness; determining a target screen brightness matching the ambient brightness, and setting the brightness of the LED screen according to the target screen brightness; adjusting a conventional gamma curve according to the ambient brightness to obtain an adjusted gamma curve; and adjusting the contrast of the LED screen after brightness setting according to the adjusted gamma curve. This method can effectively improve the contrast of the LED screen and ensure clear image display.

This invention provides a myopia screening device. The first end of the housing is designated as the detection end for testing the subject's eyes. A visual target screen, a screening camera, and an optical path assembly are all housed within the housing. The visual target screen is located on one side wall of the housing, the optical path assembly is positioned between the detection end and the visual target screen, and the screening camera is located at the second end of the housing. The screening camera captures a light and shadow image of the subject's pupil. A processor processes and analyzes the light and shadow image captured by the screening camera. An input device communicates with the processor and inputs the image seen by the subject on the visual target screen into the processor. This invention enables not only refractive error testing but also visual acuity testing and color blindness / color weakness testing. Furthermore, this invention can estimate the subject's visual acuity based on the refractive error test results, generate a corresponding estimated visual target based on the estimated visual acuity, and quickly complete the visual acuity test, effectively shortening the visual acuity screening time.

The invention discloses a screen control method and related equipment, and relates to the technical field of vehicle-mounted screens, and the method comprises the steps: obtaining the first identity information of a main driver seat user and the second identity information of a co-driver seat user; constructing a first user portrait based on the first identity information; constructing a second user portrait based on the second identity information; determining first display content of the main driving area based on the first user portrait and a preset safety strategy; determining second display content of the co-driver area based on the second user portrait; and controlling the target screen to present the first display content and the second display content. Through identity recognition, portrait construction, personalized content decision and split-screen presentation under security policy constraints, the problems that in the prior art, an integrated screen is single in content and tedious in operation are solved, the screen utilization efficiency is optimized, and the personalized experience of a main driver passenger and an auxiliary driver passenger is enhanced.

The invention relates to the technical field of equipment positioning detection, in particular to an intelligent recognition system and method for underwater equipment detection, and the system comprises a search data collection module, a data management center, a cooperative target screening module, an equipment search management module and an equipment detection and recognition module. The search data acquisition module acquires data of searching and positioning underwater fault equipment by an underwater robot and historical search data, the data management center stores and manages all the acquired data, and the cooperative target screening module screens out a robot cooperating with the current underwater robot to search the underwater fault equipment. The device search management module controls the cooperative target to perform cooperative search on the underwater fault device, and the device detection and recognition module detects and recognizes the device fault position when the current underwater robot searches and reaches the position where the underwater fault device is located, so that the accuracy of positioning the underwater fault device by the underwater robot is improved, and the accuracy of positioning the underwater fault device by the underwater robot is improved. And time is saved for equipment detection and identification.

The invention discloses a screen control method and device, equipment and a medium, and relates to the technical field of vehicle-mounted screens, and the method comprises the following steps: obtaining biological characteristic data of a target object; determining a current state of the target object based on the biological characteristic data; and adjusting the target screen area based on the current state. According to the method, the user state is comprehensively judged by using the multi-dimensional biological characteristic data, so that the accuracy and robustness of state recognition are improved, and misjudgment and limitation possibly existing in a single data source are overcome. On the basis, by adjusting the screen display attribute, the information transmission efficiency can be effectively improved, and the distribution of screen resources is optimized while the key information is ensured to be preferentially displayed to improve the safety, so that more personalized interaction experience meeting the current demand is provided for the user.