44 results about "Phenacetin" patented technology

The invention relates to a specific probe substrate composition of cytochrome P450 (CYP450) enzyme and an application of the specific probe substrate composition in subtype enzyme activity detection of the cytochrome P450 enzyme. The composition comprises at least two of phenacetin, coumarin, amfebutamone, dextromethorphan, diclofenac and testosterone. The characteristics of multi-ion channels can be simultaneously detected by the specific probe substrate composition and a liquid chromatography-mass spectrometry technology, and the inhibition conditions of six CYP450 enzymes are determined simultaneously, so that the experiment flux efficiency is greatly improved, and the experiment cost is reduced.

The present invention relates to a diagnostic agent for diabetes, comprising a compound labelled with 13C at least at one specific position selected from the group consisting of the following (a) to (g):(a) galactose, fructose or xylose labelled with 13C at least atone specific position, or a starch composed of glucose units labelled with 13C at least at one specific position;(b) an amino acid labelled with 13C at least at one specific position;(c) lactic acid or citric acid labelled with 13C at least at one specific position;(d) a fatty acid labelled with 13C at least at one specific position;(e) a glyceride labelled with 13C at least at one specific position;(f) glycerol labelled with 13C at least at one specific position; and(g) aminopyrin of which the dimethylamino group at position 4 is labelled with 13C, phenacetin of which the ethoxy group is labelled with 13C at position 1, or methacetin of which the methoxy group is labelled with 13C.According to the present invention, there is provided a diagnostic agent for diabetes which does not impose a heavy physical burden on a subject, can give accurate test results immediately and can be used safely without side effects. The diagnostic agent of the invention makes it possible to discriminate patients with diabetes from normal subjects even under circumstances where patients are easily missed.

The invention provides a preparation method of novel catalyst manganoferrogehnite (MnFe2O4, MFO), which aims at overcoming the weaknesses that the conventional powder catalyst is unlikely to separate in the water phase. By integrating the advantageous adsorption catalytic performance of different forms of ferrous oxides and manganese oxides such as MnOx, FexOy, the content of soluble ozone in water can be effectively increased, so that the manganoferrogehnite can be used as a catalyst to effectively improve the intensified removing effect of ozone on medicines such as phenacetin and pharmaceutical and personal care products in the water; more importantly, the manganoferrogehnite has magnetic property, the separation in the water can be completed through the magnetic field, and a novel method is provided for the washing and recycling of the catalyst. In addition, the manganese and iron sources in China are rich, and the high-efficient catalyst produced by adopting the manganese and ferrum as the raw materials has the advantages of low cost, easiness in acquisition and the like. The catalyst is prepared by a method for collectively depositing manganese salt, ferrates and alkaline liquid, the process is simple, and convenience in operation is realized; moreover, the preparation period of the catalyst is short, and the potential application prospect in the field of the treatment of drinking water or sewage containing PPCPs is promising.

The invention discloses a method for rapidly starting and stably maintaining normal-temperature short-cut nitrification of municipal sewage by using phenacetin, and belongs to the technical field of biological sewage treatment. The method comprises the following steps: inoculating the whole-process nitrification activated sludge into a sequencing batch biochemical reactor, and soaking the activated sludge in the reactor with phenacetin with the concentration of 4-20 mg/L for 12-30 hours. The whole-process nitrification activated sludge is soaked in phenacetin, the ammonia oxidation activity of the reactor can be quickly recovered, the nitrite oxidation activity can be continuously inhibited, and when the ammonia nitrogen degradation rate (ARE) reaches 90% or above and the nitrite accumulation rate (NAR) reaches 80% or above, normal-temperature short-cut nitrification of the municipal sewage is formally started.

A medicine for treating toothache, dental marrow inflammation and periodontitis is prepared from VB1, VC, aminopyrine, phenacetin, coffeine, austrominal, prednisone acetate, and safflower.

The invention discloses an acetylsalicylic acid-phenacetin-caffeine sheet composition and a preparation technology thereof. The preparation technology comprises the following steps of 1, screening acetylsalicylic acid, phenacetin, caffeine, citric acid, microcrystalline cellulose, starch, sodium dodecyl sulfate, hydroxypropyl methylcellulose and polyvinylpyrrolidone K30 by a sieve of 80 meshes for next use, 2, by a fluidized drying granulator, preparing acetylsalicylic acid single-phase microsphere particles from the acetylsalicylic acid, a part of the starch and a part of the sodium dodecyl sulfate screened by the sieve of 80 meshes, 3, by the fluidized drying granulator, preparing phenacetin-caffeine mixed microsphere particles from the phenacetin, the caffeine, a part of the starch and a part of the sodium dodecyl sulfate screened by the sieve of 80 meshes, 4, uniformly mixing the acetylsalicylic acid single-phase microsphere particles, the phenacetin-caffeine mixed microsphere particles and the microcrystalline cellulose, and carrying out tabletting. The preparation technology improves stability of the drugs in the acetylsalicylic acid-phenacetin-caffeine sheet composition, reduces free salicylic acid content of the acetylsalicylic acid-phenacetin-caffeine sheet composition, and guarantees product quality stability.

The invention discloses an artificial antigen and antibody capable of simultaneously detecting acetaminophen and phenacetin and a preparation method and application of the artificial antigen and antibody. An artificial antigen 1 and an artificial antigen 2 are prepared, the artificial antigen 1 is used for preparing a bispecific antibody for simultaneously detecting acetaminophen and phenacetin, the artificial antigen 2 is used as an artificial coating antigen, the antibody has high-sensitivity and high-specificity recognition capability on acetaminophen and phenacetin, the lowest detection limits are 2.8 ng/mL and 2.1 ng/mL respectively, the cross reaction rate to structural analogues is lower than 0.1%, an immunoassay method of the acetaminophen and the phenacetin is established, and the purpose of rapidly and accurately detecting the acetaminophen and the phenacetin in food is achieved.

The invention discloses a lachnum melanin hair dye and a preparation method thereof. The preparation method is characterized in that: an agent A is prepared by dissolving para phenylene diamine, lachnum melanin, sodium sulfite, sodium bicarbonate, ascorbic acid, palmitic acid and ethylene diamine tetraacetic acid disodium in water and ammonia water to form an aqueous phase; adding into an oleic phase which is formed by heating to melt sodium carboxymethyl cellulose, nonylphenol polyoxyethylene ether and isopropanol or ethanol under stirring; and regulating the pH to be between 9.0 and 9.5 with the ammonia water; an agent B is prepared by adding the sodium carboxymethyl cellulose into water, aqueous solution of hydrogen peroxide and phenacetin, and regulating the pH to be between 3.4 and 4.0 by using phosphoric acid; and uniformly mixing the agent A with the agent B in the volume ratio of 1:(1-2) for use. By a hair-care dye with high safety, high efficiency and low toxicity provided by the invention, the content of the para phenylene diamine in the hair dye is reduced, the antioxidation, the antiradiation, the light protectiveness and the safety of the lachnum melanin are exerted, and natural and lustrous dying effects can be kept.

The invention discloses a preparation method of medicinal liquor for treating rheumatic pain. The preparation method includes steps of (1), weighing components by mass: 5-10 parts of corn cervi pantotrichum, 10-15 parts of rhodiola rosea, 5-10 parts of pepper, 10-15 parts of safflower carthamus, 8-12 parts of rhizoma corydalis, 8-10 parts of fraxinus bungeana, 12-15 parts of jasmine, 8-10 parts of scorpio, 10-15 parts of borneol, 5-8 parts of musk, 5-10 parts of Chinese lizardtail rhizome, 8-10 parts of centipede, 8-12 parts of arisaema rhizomatum, and 12-15 parts of folium artemisiae argyi; (2), smashing and mixing, immersing and cooking components by millet wine; (3), extracting the filtering slag by ethanol; (4), combining the extracting agent and the decocta; mixing the extracting agent with ethanol with volume ratio of 1: 1-1.5; (5), adding 1-1.2% of methyl salicylate, 1-1.5% of turpentine oil, 0.2-0.3% of aminopyrine, and 0.2-0.3% of phenacetin in the raw fluid of the medicinal liquor. The drug can treat both symptoms and root causes, convenient to use, free from toxic and side effects, fast in effect and not easy to relapse.

The invention discloses an ointment for treating sweaty feet and body odor, which is composed of stearic acid, potassium stearate, glycerin, stearyl alcohol, salicylic acid, phenacetin, caffeine and water, and a preparation method thereof. The ointment has the advantages of obvious curative effect, no side effects and high cure rate.