115 results about "Aminopyralid" patented technology

The invention provides a synthesis method of 2-amino pyridine compounds, belonging to the technical field of organic synthesis. The existing synthesis method has the disadvantages of difficult acquisition of raw materials, high catalyst cost, complicated reaction steps, harsh reaction conditions, serious environmental pollution, low yield, few substituent groups, specific substituent positions and atomic diseconomy. The synthesis method provided by the invention is characterized by comprising the following steps of: adding a 2,4-pentadiene nitrile compound and an amine compound in a molar ratio of 1.0:(1.0-2.5) to a solvent to form a reaction mixture; adding a base the amount of which is 0-250mol% of a substrate while stirring the reaction mixture; and then stirring at the temperature from room temperature to 150 DEG C for 3-24 hours to obtain a product namely the 2-amino pyridine compound. The synthesis method provided by the invention lowers the catalyst cost, relieves the pollution, simplifies the synthesis processes, has the advantages of mild reaction conditions, easy acquisition of raw materials, light side reaction, many substituent groups and wide application range, and has the yield of 58-81% depending on different reactions.

The invention discloses a microbial pesticide and a preparing method thereof. The microbial pesticide is prepared from, by weight, 40-50 parts of aphid killing powder, 1-5 parts of garlic oil, 20-40 parts of quinclorac, 8-12 parts of hirsutella thompsonii fisher powder, 4-8 parts of thiopyran diketone, 6-10 parts of verticillium powder, 5-9 parts of acetochlor, 2-6 parts of sophocarpidine, 1-5 parts of thiencarbazone-methyl, 1-5 parts of rhizoma cyrtomii, 1-6 parts of radix sophorae flavescentis, 1-5 parts of aminopyralid, 15-25 parts of microzyme, 4-8 parts of herba houttuyniae and 1-5 parts of octylphenol polyoxyethylene ether sulfonate. According to the microbial pesticide and the preparing method thereof, microorganism powder and plant raw materials serve as main materials, the raw materials are easy to obtain, the price is low, the adopted raw material ratio is simple, environment friendliness is achieved, the cost is low, the pesticide is excellent in effect, safe, efficient and good in degrading effect, and few residues are generated.

The invention discloses a preparation method of an imidazo-[1,2-a] pyridine compound. The preparation method comprises the following steps of: (1) adding 2-aminopyridine compound, a propiophenone compound and a condensation catalyst to an organic solvent, and heating for condensation reaction, wherein an imine intermediate is obtained after complete reaction; (2) adding a copper catalyst, an oxidizing agent, alkali the imine intermediate obtained from the step (1) to the organic solvent, heating for ring closing reaction, and carrying out post processing to obtain the imidazo-[1,2-a] pyridine compound after the complete reaction. The preparation method disclosed by the invention has the advantages of wide source, cheapness and easiness for obtaining of used raw materials, namely the 2-aminopyridine compound and the propiophenone compound, is easy to operate without a complex post processing process and is suitable for the large-scale preparation of the compound.

The invention provides a quantitative determination method of aminopyridine carcinogenic substances in meat products. The quantitative determination method comprises a step of meat product pretreatment, and a step of UHPLC-MS / MS quantitative determination. The meat product pretreatment step mainly comprises following steps: a trichloroacetic acid aqueous solution is added, and homogenizing is carried out; ultrasonic extraction and centrifugation are carried out, and a supernate is collected; pH value of the supernate is adjusted, and the supernate is delivered through an activated MCX small column; a hydrochloric acid solution, a methanol solution, and ammonium hydroxide-methanol are used for elution successively; and acetonitrile is added for redissolving, and a caffeine methanol solution is added. In the step of UHPLC-MS / MS quantitative determination, UHPLC-MS / MS detection is carried out, retention time of a standard substance and retention time in a sample spectrum are compared, and the content of the aminopyridine carcinogenic substances in barbecue is obtained via calculation. Compared with the prior art, the quantitative determination method possesses following advantages: accuracy rate is increased, adding standard recovery rate is increased, the pretreatment steps are simplified, detection cost is reduced, detection limit is low, accuracy is high, repeatability is high, and the quantitative determination method can be used for quantitative determination of aminopyridine compounds in a plurality of commercially available meat products.

The invention provides a hydroxamic acid fragment-containing aminopyridine derivative as shown in a formula V, pharmaceutically acceptable salt thereof as well as application of the aminopyridine derivative to anti-tumor aspect (the formula is shown in the description). The compound has high protein kinase inhibition activity and histone deacetylase inhibition activity, has high inhibition activity on various human tumor cells, has weak inhibition effect on normal cells, has low toxicity and is suitable for being applied to development of anti-tumor medicines.

The invention discloses a mixed herbicide containing aminopyralid and quinclorac, which belongs to the technical field of pesticide. The herbicide uses aminopyralid and quinclorac as main effective components, wherein the mass ratio of aminopyralid to quinclorac is 0.1-80: 0.1-80. The mixed herbicide provided by the invention is applied to non-cultivated land, orchards, woodland, paddy fields and wheat paddocks for post-emergence weeding and has the advantages of a wide weed control spectrum, fast action, high efficiency, low toxicity, safety, environment friendliness and the like.

The invention relates to a wheat field composite herbicide containing quinmerac and tribenuron-methyl. The herbicide is characterized in that the herbicide comprises main effective components A, B and C, wherein A is quinmerac, B is tribenuron-methyl, C is any one of clopyralid, aminopyralid, chipton, and carfentrazone-ethyl; the weight ratio of A:B:C is 1-150:1-20:0.1-50, the herbicide is used for wheat field post-emergence stem leaf treatment, and is used for control of broad-leaf weeds with substantial synergistic effects, such as Galium aparine, Veronica didyma, Shepherdspurse, Stellaria media, Stellaria uliginosa, and the like.