The invention relates to a recombinant humanized
type I collagen gel
scaffold for vaginal relaxation, as well as a preparation method and application of the recombinant humanized
type I collagen gel
scaffold for the vaginal relaxation. The gel
scaffold comprises the following components in concentration by
mass: 0.002 to 0.5% of recombinant humanized soluble high-activity
type I collagen, 15 to 25% of
poloxamer 407, 1 to 8% of
poloxamer 188, 2 to 6% of glycerin, 0.5 to 2.5% of
sodium hyaluronate, 0.02 to 2% of Nepal
sodium methyl ester, 0.3 to 1% of phenoxy
ethanol and the balance of deionized water. The recombinant humanized type I
collagen gel scaffold for the vaginal relaxation disclosed by the invention has an obvious effect in significantly improving the vaginal relaxation, further can repair the problems of
itching, scorching hot, chapping and the like caused by
vaginal dryness, and further has the effects of increasing the vaginal elasticity, relieving pains during
sexual intercourse, increasing the sexual satisfaction and
vaginal secretions, reducing vaginal inflammatory responses, enhancing the vaginal
micro environment moisture, improving the
vaginal dryness and maintaining the vaginal
micro environment pH. The combination is free of adverse stimulus allergic reactions and
immune rejection, and can be used for being prepared into
suppository dressings, gel dressings and lotions, and is worthy of being popularized clinically.