Composite probiotics micro-ecological formulation and preparation method

A technology of compound probiotics and microecological preparations, applied in the direction of drug combination, pharmaceutical formula, medical raw materials derived from bacteria, etc., can solve problems such as irritation, enhance human resistance, prevent and treat intestinal diseases, and restore intestinal flora. balanced effect

Inactive Publication Date: 2009-08-05
上海谱莱生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] The purpose of the present invention is to overcome the deficiencies in the prior art, to provide a method that can significantly promote intestinal absorption of nutrients, stimulate intestinal peristalsis, solve the pro

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Example 1 Composite probiotic microecological preparation for infants

[0031] In this example, the compound probiotic probiotic microecological preparation for infants is mainly aimed at the compound probiotic microecological preparation used by infants aged 0 to 3 years old. The product formula is composed of: 10% Bifidobacterium infantis, 3% Bifidobacterium bifidum, 2% Bifidobacterium longum, 5% Lactobacillus acidophilus, 15% fructooligosaccharides, 40% skim milk powder, 24.9% maltodextrin, 0.1% vanillin.

[0032] Select Bifidobacterium infantis strains, Bifidobacterium bifidum strains, Bifidobacterium longum strains, and Lactobacillus acidophilus strains, and after single-strain fermentation, obtain four strains of fermentation liquid; the initial pH control of the fermentation medium At 4; the culture temperature is controlled at 30°C; the culture time is subject to the pH 5 of the fermentation end point; after the fermentation of the strain, take the fermentation ...

Embodiment 2

[0036] Example 2 Composite probiotic microecological preparation for children

[0037] The composite probiotic probiotic microecological preparation for children in this example is mainly aimed at the composite probiotic probiotic preparation used by children over 3 years old. Bifidobacterium adolescentis, 2% Lactobacillus acidophilus, 1% yeast, 15% xylooligosaccharides, 15% fructooligosaccharides, 25% skimmed milk powder, 29.9% dietary fiber, 0.1% vanillin.

[0038] Select Bifidobacterium infantis strains, Bifidobacterium bifidum strains, Bifidobacterium adolescentis strains, Lactobacillus acidophilus strains and yeast strains, and after single-strain fermentation respectively, the fermentation broths of five bacterial strains are obtained; fermentation medium The initial pH is controlled at 5; the culture temperature is controlled at 40°C; the culture time is subject to the pH 4 of the end point of fermentation; 10% lactose powder is emulsified as an emulsification protecti...

Embodiment 3

[0042] Example 3 Compound probiotic microecological preparation for adults

[0043] In this example, the compound probiotic microecological preparation for adults is mainly aimed at the use of the compound probiotic microecological preparation for adults, and the product formula is divided into: 4% Bifidobacterium bifidum, 3% Bifidobacterium adolescentis, 1% Lactobacillus acidophilus , 1% Lactobacillus bulgaricus, 1% Lactobacillus casei, 2% yeast, 13% soybean oligosaccharides, 15% isomaltooligosaccharides, 35% skimmed milk powder, 24.8% dietary fiber, 0.2% vanillin.

[0044] Select Bifidobacterium bifidum strains, Bifidobacterium adolescentis strains, Lactobacillus acidophilus strains, Lactobacillus bulgaricus strains, Lactobacillus casei strains and yeast strains, and obtain fermentation broths of 6 strains after single-strain fermentation respectively; The initial pH of the fermentation medium is controlled at 4; the culture temperature is controlled at 35°C; the culture tim...

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Abstract

The invention relates to a composite probiotic bacterium microecological preparation and a preparation method thereof. The preparation is prepared by mixing 1.0 to 20 percent of composite microbial bacterium powder, 5.0 to 50 percent of composite oligosaccharide, 30 to 80 percent of auxiliary protective carrier and 0.1 to 0.2 percent of edible essence. The composite probiotic bacterium microecological preparation is prepared from a beneficial microbial preparation and a microbial growth-promoting factor, namely the oligosaccharide, through special combination and technological recombination. The composite probiotic bacterium microecological preparation has the advantages that beneficial active bacteria and the oligosaccharide promote each other, so that the composite probiotic bacterium microecological preparation has the advantages of obviously improving the microecological environment of the whole intestine and contributing to the digestion, preventing and treating intestine diseases, treating diarrhea, chronic diarrhea, diarrhea which can not be cured by antibiotic, constipation, dyspepsia and abdominal distension which are caused by intestine dysbacteriosis, recovering the intestine flora balance, protecting the liver, reinforcing the functions of detoxication and toxin expulsion of the liver, reinforcing the disease prevention and resistance such as the resistance of human body, and the like.

Description

technical field [0001] The invention relates to a microbial preparation, in particular to a compound probiotic microbial ecological preparation and a preparation method thereof. Background technique [0002] The number of flora in the human gastrointestinal tract is huge. Under normal circumstances, the intestinal flora reaches a dynamic balance, forming a micro-ecosystem that has a great effect on human health. Improper diet / cleanliness, taking antibiotics, high stress and mental tension and many other factors can cause the imbalance of digestive tract flora and lead to diseases. [0003] Microecological preparations are biological preparations containing beneficial microorganisms (probiotics) and their metabolites developed according to microecological theory. By regulating and maintaining the microecological balance in the intestinal tract, the purpose of improving human health is achieved. [0004] Microecological preparations include three parts, namely probiotics, pre...

Claims

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Application Information

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IPC IPC(8): A61K35/74A61K36/064A61P1/14A61K35/745A61K35/747
Inventor 方曙光
Owner 上海谱莱生物技术有限公司
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