In a method and an arrangement for evaluating operational effectiveness of an implantable medical device for different lead placements associated with the medical device, a measuring unit records signals that are characteristic of cardiac activity at respectively different lead positions, and these signals are stored. A processor accesses the stored signals and, from the stored signals, determines a measure of cardiac activity at each of the lead positions. The recorded signals may be intracardiac ECG signals, surface ECG signals, heart sound signals obtained from a microphone, or impedance signals. The lead position at which the best hemodynamic behavior of the heart is identified from the analysis of the stored signals, and is determined as being the optimum site for placement of the electrode leads.