57 results about "Parasystole" patented technology

A system and method for monitoring at least one chamber of a heart (e.g., a left ventricular chamber) during delivery of extrasystolic stimulation to determine if the desired extra-systole (i.e., ventricular mechanical capture following refractory period expiration) occurs. The system includes an implantable or external cardiac stimulation device in association with a set of leads such as epicardial, endocardial, and / or coronary sinus leads equipped with motion sensor(s). The device receives and processes acceleration sensor signals to determine a signal characteristic indicative of chamber capture resulting from one or more pacing stimulus delivered closely following expiration of the refractory period. A threshold optimization method optionally evaluates capture and at least one of: runs an iterative routine to establish or re-establish chamber capture for the PESP therapy, sets a logical flag relating to chamber capture status and stores parameter(s) relating to successful chamber capture for one or more subsequent cardiac cycles.

An apparatus for assessing cardiovascular status of a mammal comprises a system for locally applying a pressure to an artery capable of restricting blood flow through said artery, a wideband external pulse transducer having an output and situated to measure suprasystolic signals proximate to said artery, and a computing device receiving said output for calculating vascular compliance values. The method described is particularly useful for determining cardiac output, assessing whether a pregnant female has preeclampsia or a patient has cardiac insufficiency, or assessing cardiac arrhythmias.

The invention discloses a method and a device for quantitatively analyzing heart sound signals. The method comprises the following steps of: acquiring multiple heart sound signals at clinical auscultation positions; preprocessing the acquired multiple heart sound signals; extracting heart sound envelope curves and characteristic parameters of the preprocessed multiple heart sound signals respectively; dividing a systole period in a cardiac cycle of each heart sound signal into a first heart sound period and a systolic murmur period, dividing a diastole period into a second heart sound period and a diastolic murmur period, and computing heart sound energy in all periods respectively; and computing the percentage of the heart sound energy in all the periods in the whole cycle to determine the intensity of normal heart sound and the emergent time and intensity of murmurs. By the method for quantitatively analyzing the heart sound signals, the intensity, the emergent time and the duration time of all components of heart sound can be quantitatively analyzed, and an analysis result can be used as a diagnosis basis for clinical common cardiovascular diseases; and the method and the device are used for evaluating the relationship between cardiac murmur types and the cardiovascular diseases.

Methods and systems are disclosed that characterize cardiac function using an acceleration sensor to acquire and analyze the frequency dynamics associated with the isovolumic contraction phase (“ICP”). This information can be used to characterize heart function; optimize therapy for cardiomyopathy, including CRT therapy (including pacing intervals and required pharmacologic therapy); and to optimize CCM therapy. In addition, this information can be used to identify target pacing regions for CRT lead placement. Further, analyzing the frequency dynamics can be used to characterize pathologic heart vibrational motion, such as mitral regurgitation and the third or fourth heart sound, and the response of this motion to therapy for cardiomyopathy.

Devices, methods, and systems for determining a systolic pulmonary artery pressure index (PAPi) corresponding to pulmonary artery pressure (PAP) and / or right ventricular systolic pressure (RVSP) use lead-based electronic sensors detecting right heart valvular events. Suitable sensors include impedance sensors, accelerometers, cardiomechanical electric sensors, and sonomicrometers.

A method and apparatus for optimizing and assessing the response to extra-systolic stimulation (ESS) are provided. An optimization / monitoring parameter is calculated as a function of potentiation ratio, PR, and recirculation fraction, RF, derived from measurements of myocardial contractile function during and after ESS. PR may be computed as the ratio of the contractile function on post-extra-systolic beats during ESS to baseline contractile function. RF may be computed as the slope of a linear regression performed on a plot of the contractile function for a post-extra-systolic beat versus the contractile function for the previous post-extra-systolic beat after ESS is ceased. The ESI resulting in a maximum optimization / monitoring parameter, preferably computed as the product of PR and RF, is determined as the optimal ESI. The operating ESI may be automatically adjusted, and / or PR and RF data may be stored for monitoring purposes.

A system for crossing a heart valve with a guidewire includes an advancement motor and a controller. The controller controls when the advancement motor advances and retracts the guidewire. The controller is coupled to an electrocardiogram device and determines the systolic and diastolic phase of the heart from information / data from the electrocardiogram device. The guidewire advances or retracts based on the controller's determination of the systolic or diastolic phase corresponding with the heart valve being in an open configuration. The system may include a catheter including a lumen through which the guidewire is disposed. The system may further include a sensor. The sensor is in communication with the controller, and the controller will stop advancement of the guidewire if the controller determines the guidewire has not advanced between open leaflets of the heart valve based upon information / data from the sensor.

A method of diagnosing pathologic heart conditions in which a time series of heart sounds is filtered and parsed into a sequence of individual heart cycles. A systolic interval as well as systolic sub-intervals are identified for each heart cycle. An energy value is computed for the systolic sub-interval of one or more heart cycles. The energy value computed is proportional to the energy level associated with the filtered series of heart sounds. A composite energy value is then computed for the systolic sub-intervals of one or more heart cycles and compared to a threshold level in order to distinguish between a normal heart and a pathologic heart. The system corresponding to the method is comprised of a portable computing device that manages data collection and stores data collected from new patients, and analyzes data.

An apparatus for detecting vital functions has a pulse wave sensor attachable to a body and a control unit. The control unit checks if amplitude of pulse wave signals produced from the pulse wave sensor varies. The control unit further checks if a large change in the amplitude during a systolic phase of a pulse wave corresponding to the systolic phase of the heart. If a first large change in the amplitude during a diastolic phase of a pulse wave corresponding to the diastolic phase of the heart, it is highly probable that a motion artifact has occurred. Therefore, a motion artifact flag is set. Next, it is checked if the amplitude in the next diastole is changing by more than 30%. if it is presumed that the occurrence of cough is highly probable, a cough flag is set. if it is neither the motion artifact nor the cough, then a yawn flag is set.

The invention provides a heart sound signal characteristic automatic extraction method comprising the following steps: preprocessing a heart sound signal, and using a viola integration waveform method to extract a signal envelope; segmenting the signal envelope, and positioning so as to obtain a first heart sound segment zone and a second heart sound segment zone; calculating a first heart sound segment zone first heart sound characteristic constant and a second heart sound segment zone second heart sound characteristic constant; extracting heart sound signal characteristics. The heart sound signal characteristic automatic extraction method is simple in calculation, fast in speed, can accurately position a heart sound signal diastole stage and contraction stage, can effectively extract heart sound signal characteristic envelope, can reserve original information on the heart sound signal, and is very suitable for analyzing and processing heart sound signal containing noises and interferences.

A method, an apparatus, and a kit including the apparatus and a fluorescence agent are provided for measuring a time-varying change in an amount of blood in a tissue volume, and include exciting a fluorescence agent in the blood, acquiring a time-varying light intensity signal during a pulsatile flow of the blood through the tissue volume, the pulsatile flow having a systolic and a diastolic phase resembling a conventional photoplethysmogram, and processing the acquired signal by applying a modified Beer-Lambert law to obtain a measurement of the time-varying change in the amount of blood in the tissue volume. The instantaneous molar concentration of the fluorescence agent is determined by utilizing a concentration-mediated change in a fluorescence emission spectrum of the fluorescence agent. There is further provided a fluorescence agent for use in the method.

Described herein are inventions is directed to methods of treating a cardiac dysfunction and symptoms of cardiac dysfunction in a subject that includes administering an amount of probenecid effective to treat a symptom of cardiac dysfunction. The probenecid may be administered in at least one of an injection, orally, or transdermally. The amount of probenecid is sufficient to result in an improved performance on a standardized 6 minute walk test, an improved New York Heart Association (NYHA) classification, a lower diuretic dose requirement, a lower serum BNP levels, a normalization of serum sodium concentrations, and combinations thereof In an embodiment, probenecid is administered over a period of about 8 hours to about 24 hours. Probenecid may be used for short term treatments, i.e., less than a week, or it may be administered in a long term manner, i.e., over a period of weeks, months, or even years. Probenecid may be administered in an amount sufficient to treat the symptoms of cardiac dysfunction.

The invention discloses a dynamic evaluation method for the cardiac reserve function of healthy pregnant women in moderate-intensity exercises, belonging to the technical field of pregnancy healthcare of pregnant women and particularly exercise healthcare of pregnant women. The method is characterized by being realized in a cardiac reserve function computer evaluation system when the pregnant women take moderate-intensity exercises and comprising the following steps: determining the healthy pregnant women from the personal medical information of the pregnant women sequentially according to the health hierarchical screening rule and pregnant-women risk grouping rule; screening out low-risk pregnant women of which the D / S value is less than 1.0 during exercises by a classifying rule based on the ratio D / S of the diastole time limit to systole time limit according to the pulse wave data measured in exercises; detecting the cardiac reserve function and target heart rate range of the pregnant women by using pulse waves for other healthy pregnant women, and calculating the target heart rate intensity range according to the two modules; and evaluating the exercise time by a pregnant-women exercise time evaluation module according to the international exercise standard for the pregnant women so as to obtain an exercise prescription composed of the target heart rate intensity range and exercise cardiac reserve function value to guarantee effective and safe exercises of the pregnant women.

According to the embodiment, the invention discloses a method and equipment for transmitting cardiac sound data. The method comprises the following steps: collecting cardiac sound signals by virtue ofa sensor at a configurable sampling frequency; and in accordance with configurable signal processing parameters, processing the collected cardiac sound signals, so that the cardiac sound data is generated, wherein the cardiac sound data includes at least one of a heart rate, a first cardiac sound amplitude, a second cardiac sound amplitude, diastole time limit and systole time limit. The method further comprises the following steps: packaging the cardiac sound data into a data package, and transmitting the data package to electronic equipment by virtue of a low-power-consumption Bluetooth channel, wherein the data package at least includes identification fields and cardiac sound data fields. According to the embodiment, the cardiac sound signals are collected and processed by virtue of the configurable processing parameters, and the cardiac sound data package in a preset format is transmitted through low-power-consumption Bluetooth, so that the cardiac sound data can be transmitted efficiently with low power consumption.

The invention provides a method for continuous blood pressure measurement based on multi-parameter combination. Besides blood pressure calibration based on pulse wave transmission time, the method also comprehensively considers a maximum value a01 of a first-order derivative of a blood oxygen volume wave which stays in the same cycle with an electrocardio-signals, a time difference a2 between two systole peak points in two adjacent periods, a time different a3 of two minimum points, a time different a4 of two diastole peak points, a difference a5 of two dicrotic notch points, an amplitude a6 of systole peak points, an amplitude a7 of the minimum point, an amplitude a8 of diastole peak points, an amplitude a9 of dicrotic notch pints, a systole area a10, a diastole area a11, an area a12 of the blood oxygen volume waves, an area ratio a13, a difference a14 of two peak points in the same cycle, a difference a15 between the systole peak point and the minimum point in the same cycle, rise time a16, a time increment a17, an increment coefficient a18, and a reflection coefficient a19. A blood pressure model can be established by a BP neural network according to the 18 parameters. A blood pressure can be predicted according to the model.

The invention relates to a magnetic resonance data collection method and a magnetic resonance imaging system. The method comprises the steps that electrocardio-signals are acquired in real time, whether a heart stays in a heartbeat contraction period or a heartbeat relaxation period is judged, and a judgment result is transmitted to a magnetic resonance scanning sequence; and the magnetic resonance scanning sequence executes a corresponding collection method according to the judgment result. According to the invention, a cardiac impulse state is judged in time, and strong high-order flow effects are avoided according to the cardiac impulse state when a phase encoding step of k space is collected, so that influences of the high-order flow effects can be reduced to the hilt. In addition, the total quantity of phase encoding steps is unchanged, so that use of the magnetic resonance data collection method provided by the invention will not change the total duration for sequence magnetic resonance data collection. The method and the system provide by the invention have the advantages of high timeliness, high flexibility, outstanding effects and high practical values.

The invention discloses a dynamic myocardium activity detection method. The dynamic myocardium activity detection method comprises the steps that a non-layer-selection inversion pulse is applied on a detected object; a balanced steady-state free procession is used for carrying out real-time sampling on the inversion recovery process of signals in the whole cardiac cycle including a diastole period and a systole period, and a set of heart cine-MRI images; a small-angle excitation balanced steady-state free procession within a preset range is used for collecting a reference image; phase sensitivity inversion recovery reconstruction is carried out on the collected heart cine-MRI images through the reference image. By the adoption of the dynamic myocardium activity detection method, the collection efficiency and imaging efficiency can be improved, and the dynamic myocardium activity is effectively measured. The invention further provides a dynamic myocardium activity detection system.

The present application relates to the field of intelligent decision making, which integrates the local features of each phase of a heart sound cycle and the global features of a heart sound signal toidentify the heart sound signal, and the recognition accuracy is higher. The invention discloses a computer device, a heart sound recognition device, a method, a model training device, and a storagemedium; the computer device includes a memory and a processor, and the processor is configured to execute a computer program stored in the memory and implement the computer program: the acquired heartsound signal is pre-processed; a first heart sound data, a systolic data, a second heart sound data, and a diastolic data are obtained from the pre-processed heart sound signal; the first heart sounddata, the systole data, the second heart sound data, and the diastolic data are processed according to processing rules to obtain local features; the global characteristics of the pre-processed heartsound signal are obtained according to a trained neural network model; based on the trained heart sound recognition model, the type of the heart sound signal is identified according to the local feature and the global feature.

A negative pressure rehabilitation therapeutic instrument for controlling male ED function by means of electrocardio-synchronization is characterized in that an electrocardio-collector is connected with a single chip microcontroller which is then connected with a vacuum pump; the vacuum pump is again connected with a vacuum accumulator which is connected with an electromagnetic valve; the electromagnetic valve is connected with a vacuum tube; and the single chip microcontroller is respectively connected with a controller and a display screen. The negative pressure rehabilitation therapeutic instrument has the technical advantages of convenient use and simple structure. The single chip microcontroller collects signals in a heart systolic period on the basis of the electrocardio-collector, starts a vacuum generation device system when arterial blood is injected into the penis in the heart systolic period, controls a vacuum therapy tube to conduct intermittent actions synchronous with theheart, and causes the arterial blood with oxygen to be injected into the penis of a patient, thus achieving the effect of curing the male sexual dysfunction.

The present invention provides a system and method for estimating a blood flow waveform contour from a pressure signal. An arterial or ventricular pressure signal is acquired from a pressure sensor. Landmark points are identified on the pressure waveform that correspond to features of a flow waveform. In one embodiment, the landmark pressure waveform points correspond to the onset of flow, the peak flow, and the end of the systolic ejection phase. The landmark pressure waveform points define a contour that approximates the flow contour. Beat-by-beat flow contour estimation can be performed to allow computation of flow-related hemodynamic parameters such as stroke volume or cardiac output for use in patient monitoring and / or therapy management.

A method and apparatus determine certain cardiac medical parameters that are useful is diagnosing cardiovascular disease. The apparatus is designed to carry out the method, which includes the steps of:(a) inflating a blood pressure cuff on the brachial artery to a supra-systolic pressure;(b) sensing a sequence of pressure pulse waveforms associated with the brachial artery that result from a plurality of cardiac ejection cycles;(c) averaging the waveforms to produce an average, representative waveform having an initial, incident wave portion and a reflected wave portion;(d) analyzing the representative waveform to determine a value of one or more cardiac medical parameters including the reflection wave ratio (RWR), the reflected wave transit time (RWTT), the maximum amplitude of the initial pressure wave (PS1), the maximum rise (slope) of the initial pressure wave (dp / dt), and / or the systolic ejection period (SEP); and(e) displaying the value of the medical parameter(s).

A method and apparatus are disclosed for determining certain cardiac medical parameters that are useful is diagnosing and treating cardiovascular disease. The apparatus is designed to carry out the method, which includes the steps of:(a) inflating a blood pressure cuff on the brachial artery to a supra-systolic pressure;(b) sensing a sequence of pressure pulse waveforms associated with the brachial artery that result from a plurality of cardiac ejection cycles;(c) averaging the waveforms to produce an average, representative waveform having an initial, incident wave portion and a reflected wave portion;(d) analyzing the representative waveform to determine a value of one or more cardiac medical parameters including the reflection wave ratio (RWR), the reflected wave transit time (RWTT), the maximum amplitude of the initial pressure wave (PS1), the maximum rise (slope) of the initial pressure wave (dp / dt), and / or the systolic ejection period (SEP); and(e) displaying the value of the medical parameter(s).

The invention relates to an artificial valve intervention replacement device applied to mitral insufficiency. The device comprises a supporting body and multiple artificial valves, the lower edge of the supporting body is of a conical cylinder structure with a D-shaped cross section, multiple stopping ropes are arranged in the supporting body, and the artificial valves are connected to the lower edge and can move along with motion of the natural valve of a patient. According to the intervention replacement device, the functions of the left chamber outflow channel and the aortic valve are not influenced, the function of the natural valve of the mitral valve is reserved, the natural blood flow is used for driving the artificial valve and the aortic valve to move in the same direction, and the artificial valve can be completely closed at the contraction period to prevent backflow of the mitral valve.

An ultrasound image diagnosis apparatus and an ultrasound image processing method that can automatically display a pair of a cardiac systolic end period image and a cardiac diastolic end period image based on living body signal data. A plurality of ultrasound images are collected from a patient and stored in a memory in correspondence with living body signal data, such as an ECG wave. When a freeze instruction is input during a reproduction of ultrasound images, a pair of images of a cardiac diastolic end period and a systolic end period is searched for going back from the freeze input time. A pair of the diastolic end period image and the systolic end period image is automatically displayed on a screen of the ultrasound image diagnosis apparatus.

The invention relates to a wrist blood pressure monitor and a measurement method thereof. The method comprises the steps that after a microprocessor receives a measurement signal, an electromagnetic air vent valve is turned off; a pressurization air pump is turned on, a pressure value of a wrist strap is read, whether or not the pressure value reaches the judgement pressure is judged, if yes, thepressurization air pump is turned off, a rubber air release valve is turned on and air is slowly released at the same time, the pressure value of the wrist strap is read, and a pulse wave signal is extracted through a Butterworth band pass filter; the pulse wave signal forms a pulse wave envelope line, a peak point corresponding to the maximum value point of the pulse wave envelope line is used asa demarcation point, the pulse wave envelope line is divided into an uphill segment and a downhill segment by the demarcation point, a blood pressure value at the contraction period is determined through the uphill segment, and a blood pressure value at the relaxation period is determined through the downhill segment. According to the wrist blood pressure monitor and the measurement method thereof, the cost is relatively low, the stability is good, and the method is not easily interfered; the wrist blood pressure monitor establishes communication through Bluetooth and a mobile terminal and uploaded to a cloud platform, and remote network monitoring of a doctor for the blood pressure of a patient is achieved.

The present invention relates to a system for measuring the arterial parameters. The system of the invention comprises a signal unit for providing radio frequency (RF) ultrasound signal and demodulated RF ultrasound signal and of the data relating thereto from the signal acquired therefrom; a detection unit for detecting the presence of blood flow in an artery; an identification unit for identifying the said artery; a processing unit for processing the said data and for providing the distension waveform of the said artery; and an estimating unit for estimating at least one of a plurality of localized arterial parameters of the said artery. The invention also relate to a method for measuring the arterial parameters by the system of the invention. The invention has the advantage of measuring localized blood pressure continuously and also other localized arterial parameters such as Peak Systolic Velocity, Pulse Wave Value and arterial compliance measures, in a non-imaging, non-invasive and cuff-less manner.

A system for detection of frequency power for diagnosing coronary artery disease (CAD), comprising: an acoustic sensor to be placed on the chest of a patient to generate acoustic signals SA: a memory adapted to store acoustic signals SA; a control unit adapted to receive said acoustic signals SA; the control unit comprising: an identification unit to identify diastolic or systolic periods in a predetermined time period and to generate a period signal SP, a filtering unit adapted to apply a filter to said identified periods to generate a low frequency band signal SLFB indicating low frequency bands of identified periods; a calculation unit to estimate the power in said low frequency band of identified periods, to calculate a low frequency power measure and to generate a low frequency power measure signal SLFP. The invention also relates to a stethoscope and a method for detection of low frequency power.

An implantable medical device, is designed to collect a signal representative of the electric activity of the heart and determine a cardiogenic impedance signal for at least a portion of the heart. An R-wave detector of the IMD detects the timing of an R-wave during a cardiac cycle based on the signal representative of the electric activity. A minimum detector detects the timing of a cardiogenic impedance minimum in the cardiogenic impedance signal and within a systolic time window of the cardiac cycle. A detected arrhythmia is then classified by the IMD based on the timing of the R-wave detected by the R-wave detector and the timing of the cardiogenic impedance minimum detected by the minimum detector.