The invention relates to a method and a system for testing nuclear power station pipeline leakage rate. The method includes: generating corresponding media with a medium generator; measuring medium mass through a mass flowmeter; cooling media, which is mixed by a mixer and flowed out from a test section, with a condensing device, measuring the media with the mass flowmeter, comparing measured mass with input mass, and regarding the measuring result as creditable if measured mass equals to or is close to the input mass; otherwise, repeating the test; and cutting open the test section, detecting crack surface roughness and a runner, using the detecting value as input of a leakage rate program, and comparing difference between the result of the leakage rate program and the measuring result. Crack size is simulated to build relation of flow and defined size, leakage test under actual working conditions can be performed aiming at actual cracks, and leakage amount of different load and crake forms can be measured.