606 results about "Femoral head necrosis" patented technology

The invention relates to a medical implant part for femoral head joint surface depression or I-stage or II-stage femoral head necrosis, namely a porous tantalum rod. One end of the implant part is provided with a connection fastening structure connected with a bone tissue, and a through hole is formed in the center of the tantalum rod; the porous tantalum rod is made of a porous tantalum material with a foam structure of pore three-dimensional communicated distribution, and is sintered by adopting a foam impregnation method; and tantalum powder particles have a sinter neck structure on a foam frame formed by accumulating the sintered pure tantalum powder. The through hole in the porous tantalum rod facilitates accurate positioning in an operation; and a related object can be picked out and injected conveniently through the through hole, so that the effect of constant pressure reduction can be achieved.

The invention discloses a metal bone supporter for medical bone substitute, which comprises a supporter and a connector component; every component of the metal bone supporter is functionally and structurally designed according to anatomical data and biomechanical data; the data of the supporter component is input to an electron beam melting fabrication device, and titanium alloy powders in the device is able be scanned, melted and molded through electron beams, to form a cylinder with the strength and elastic modulus similar to cancellous bones of human body; the supporter component is a porotic spongy body structure with threads on an end, and porous structure forms a rough surface; The connector component is made through mechanical treatment, with smooth surface and dense solid mass inside, and thread on an end, and is connected to the supporter component as a removable body. The invention has the porous structure for bone growing, high surface friction coefficient, stable structures and mechanical properties similar to bones, and is able to support the femoral head necrosis parts, slow down the necrosis speed and prolong or avoid the hip joint replacement. Thus, the invention is convenient for popularization and application.

The invention relates to a traditional Chinese medicine for curing mammary hyperplasia, which comprises oral administration Chinese traditional pills and external application plaster. The oral administration Chinese traditional pills comprise 23 Chinese herb medicines, while the external application plaster comprises 32 Chinese herb medicines. The ingredients of the traditional Chinese medicine formula is mixed compatibly and properly; the plaster and the oral administration pills of the invention can effectively cure the mammary hyperplasia caused by various reasons and has fast efficacy, short course of treatment, high cure rate and low cost. The traditional Chinese medicine of the invention has unique healing efficacy to breast adenofibroma, breast cancer, nipple discharge, mastalgia, mastitis, breast deformity, micromazia, osteomyelitis, femoral head necrosis, various sores, lymphoid tuberculosis and eye-mouth deviation.

The invention provides an acquisition method for exosomes derived from human urinary cells. The acquisition method includes the steps that firstly, human urine source cells are separately cultured, a culture medium is collected, the culture medium of the human urine source cells is filtered through a 0.22-micrometer filter membrane, and then large cell fragments and other impurities are removed; then an organelle is centrifugally removed, and supernatant is reserved; a membrane capable of intercepting 100KD molecular weight is used, the exosomes in the supernatant are centrifugally intercepted, after interception, PBS is used for eluting the membrane, and an exosome concentrated solution is obtained. The exosomes can be used for preparing medicine with the effects of resisting apoptosis, promoting angiogenesis, restoring ischemia damage and promoting cell growth and used for treating skin defects, skin ulcers, pressure sores, bone defects, bone ununion, femoral head necrosis, renal injury, ischemic injury, spinal cord injury, islet damage, diabetes, complications of diabetes, Alzheimer's diseases and the like.

The bone-setting silkyl fowl ointment as one bone wound and disease treating medicine is prepared with silkyl fowl, curcuma root, myrrh, corydalis tuber, ground beetl and other 24 kinds of Chinese medicinal materials and through heatingin sesame oil to 200-300 deg.c and after keeping leat for 15-25 hours mixing with minium. It is used to treat cervical spondylosis, protrusion of lumber interverterbral disc, femoral head necrosis, arthritis, hyperosteogeny, fracture and other bone diseases, and has the features of high curative rate, low cost and no toxic side effect.

The invention relates to a medical permanent implantation object, in particular to a medical implantation porous tantalum rod used for treating early-mid femoral head necrosis. The porous tantalum rod comprises a body, wherein one end of the body is provided with a groove, the other end of the body is provided with a threaded structure, and a notch is formed in the end surface of the tail end of the threaded structure. One end of the body of the porous tantalum rod is provided with the notch, bone marrow stromal cells or bone marrow stromal cell united biological membrane complexes and the like can be loaded, the generation of a new bone is favorably realized, a better clinical effect is particularly realized in the early femoral head necrosis treatment, and the defects of poor clinical treatment effect and the like of the existing entity type porous tantalum rod are overcome. The porous tantalum rod has the advantages that the preparation method is simple, the cost is low, the implementation and the clinical application are favorably realized, and the porous tantalum rod is suitable for the need of wide patients.

The invention belongs to the field of traditional Chinese medicines and particularly relates to a medicine for treating and preventing the rheumatism of muscles and bones, which comprises a medicine for oral administration and a medicine for external use, wherein the medicine for the oral administration comprises the following components: sea otter, sea horse, Rhizoma Drynariae, antler glue, Herba Epimedii, fleece-flower root, Eucommia ulmoides, large-leaved gentian, Monkshood, Angelica sinensis, Caulis Spatholobi, Astragalus mongholicus, scorpio, frankincense, myrrh, earthworm, Sweetgum Fruit, notopterygium root, Radix Saposhnikoviae, ground beetle, Manis pentadactyla, pseudo-ginseng, gastrodia elata, rhizoma corydalis and Ligusticum wallichii, and the medicine for the external use comprises the following components: Alangium platanifolium, rhizoma smilacis glabrae, semen brassicae, Eupolyphaga, monkshood, radix aconiti agrestis, phryma leptostachya and curcuma zedoary. The medicinalmaterials are soaked to prepare medicated wine by using 58-62 degrees of white spirit after being ground into powder, and the two medicines are combined for use. The medicine for treating and preventing the rheumatism of the muscles and bones has an obvious effect and especially has an obvious curative effect on the rheumatism of the muscles and bones, such as rheumatism, rheumatoid arthritis, lumbar intervertebral disc protrusion, lumbar muscle degeneration, Ankylosing Spondylitis, femoral head necrosis, arthroedema, sciatica, intermittent claudication, cervical vertebra ache and stiffness, amyotrophy, osteoproliferation, scapulohumeral periarthritis, arthritis, arthromeningitis and the like and has a wide application range, is economic and practical and is convenient to popularize.

The invention relates to a cell injection for treating bone injury and a preparation method thereof, belonging to the field of tissue engineering. The injection is a compound formed by mesenchymal stem cells from autologous bone marrow, temperature sensitive gel and effective trophic factors separated and extracted from autoblood. The preparation method comprises the steps of: after extracting the bone marrow of a patient, separating and extracting the mesenchymal stem cells from the bone marrow, adding no animal serum in the amplification culture process, and mixing 1*(105-108) cells with 1-5ml of biological scaffold material to form the injectable compound. The cell injection for treating bone injury is mainly used for treating bone injuries including osteoarthritis, femoral head necrosis and delayed union and disunion of bone fracture, is convenient to use, has notable effect without immunological rejection, and can alleviate the great pain of patients caused by bone injury.

A method for the treatment and/or prophylaxis of an ostenonecrotic bone disease in a mammal in need thereof, such as, e.g., idiopathic or secondary osteonecrosis, avascular bone necrosis, glucocorticoid induced bone ischemia/osteonecrosis, Legg-Calve-Perthes disease and femoral head necrosis, the method comprising administering an effective dose of a strontium-containing compound (a) to the mammal. A method for the treatment and/or prophylaxis of an osteonecrotic bone disease, such as, e.g., idiopathic or secondary osteonecrosis, avascular bone necrosis, glucocorticoid induced bone ischemia/osteonecrosis and femoral head necrosis, in a mammal who is to be or is treated with a therapeutic agent (b) known to or suspected of inducing apoptosis and/or necrosis of bone cells, the method comprising administering a strontium-containing compound (a) in combination with (b).

The invention discloses an externally applied plaster prepared from pure traditional Chinese medicines and a preparation method thereof, and belongs to the technical field of pharmacy. The externally applied plaster is a pure traditional Chinese medicine combined formula consisting of decoction and boiling type crude materials and directly added fine materials, and comprises sesame oil, yellow lead, unprocessed common monkshood mother root, unprocessed kusnezoff monkshood root, ningpo yam rhizome, fortune drynaria rhizome, obscured homalomena rhizome, szechuan lovage rhizome, myrrh, native copper, frank incense, twotooth achyranthes root, Chinese angelica, incised notopterygium rhizome root, heracleum, turmeric, shortstalk monkshood root, himalayan teasel root, white mustard seed, wooly datchmanspipe herb, common clubmoss herb, nux vomica, safflower, eucommia bark, acanthopanax bark, musk, long-noded pit viper, centipede, scorpion and borneol serving as raw materials. The finished plaster is prepared by selecting materials, decocting, removing dregs of decoction, refining, adding the yellow lead, releasing fire-toxin and stretching. The prepared plaster is used for treating rheumatism, rheumatic arthritis, scapulohumeral periarthritis, swelling and pain of joints, bone spur, hyperosteogeny, femoral head necrosis and cervical spondylosis, has the effects of activating blood circulation to dissipate blood stasis, strengthening muscles and bones, and quickly diminishing swelling and relieving pain, along with local anesthesia, and has the advantages of short treatment period, definite curative effect, no side effect and the like.

The invention relates to a medical material for orthopaedics in clinical medicine, in particular to a hollow titanium rod for supporting the collapse of the femoral head. At present, the accepted early treatment method of femoral head necrosis at home and abroad is core decompression, the remnant bone defect and femoral neck weak areas after core decompression can cause the supporting structure in the necrotic femoral head to be weakened, thus the collapse of the femoral head can not be prevented or corrected but can be quickened. The titanium screw rod of the invention is smooth, the outer diameter of the rod is 10mm, a through hole is arranged in the rod, the inner diameter of the through hole is 1.35mm, coarse threads are arranged at the tail of the screw rod, the length of the threads is 16-20mm, the diameter of a threaded core is 10mm, the outer diameter of the threads is 11mm, the distance between the threads is 1.75mm, the length of the whole screw rod is 75-110cm, and an inner hexagonal notch is arranged at the tail end. The product of the invention can be used for effectively preventing the collapse of the femoral head.

The invention relates to the technical field of traditional Chinese medicines and in particular relates to a traditional Chinese medicine pill for activating blood circulation and growing bones and a preparation method of the traditional Chinese medicine pill. The traditional Chinese medicine pill for activating blood circulation and growing bones is scientific in formula, has the effects of activating blood circulation to remove blood stasis, tonifying kidney and setting broken bones, dispelling cold and eliminating dampness, and removing obstruction in collaterals to relieve pain, is used for treating lumbocrural pain, osteoarticular pain, femoral head necrosis, hyperostosis, traumatic injury and arthritis, does not cause any adverse reaction, is safe, does not have toxic or side effects, is capable of treating both symptoms and root causes, can take effect quickly, and has wide application prospects and market potentials, and the total effective rate reaches 99%.

The invention relates to a Chinese herbal medicine for curing rheumatism, rheumatoid, hyperosteogeny and femoral head necrosis, aiming at solving the problems of the prior art that: the therapeutic effects are not ideal or perfect and can only relieve the diseases; the diseases are hard to be cured radically; the therapeutic effects for RA and femoral head necrosis are very small and even ineffective. The invention comprises dog bone, cucumber seedlings, aconite, monkshood, kusnezoff monkshood root, semen strychni, tripterygiumforrestii, sambucus williamsii hance, radix dipsaci, mistletoe, tuchung, Rhizoma Gastrodiae, clematis root, American lopseed, native copper, aristolochia mollissimaHance, olibanum, myrrh and notoginseng. The Chinese herbal medicine can be used for curing arthromyodynia diseases in Chinese traditional medicine such as rheumatoid arthritis, rheumatic arthritis, hyperosteogeny and femoral head necrosis.

The invention provides a plaster prescription for relaxing the muscles and stimulating the blood circulation and treating bone-meat pain and a preparation method thereof, and relates to the technical field of medicine. With traditional Chinese medicine health care theory as reference, the plaster prescription expands the blood vessels, promotes local blood circulation and perfects surrounding tissue nutrition to achieve the effects of detumescence, anti-inflammation and analgesia, the plaster prescription is mainly used for treating pain in the neck shoulder low-back, cervical lumbar bone hyperplasia, traumatic injury and rheumatism rheumatoid arthritis, and has a remarkable effect on such bone fractures as femoral head necrosis. The plaster prescription is significant in curative effect, quick in effect taking, wide in adaptation diseases, convenient to use, safe to use and free of toxic side effects.

The present invention is one kind of Chinese medicine for treating femoral head necrosis and belongs to the field of medicine technology. The material for the Chinese medicine includes prepared rhizome of rehmannia, drynaria rhizome, epimedium, cistanche, astragalus root and other 20 kinds of Chinese medicinal materials. The present invention has the advantages of high curative effect, high safety and low cost, and opens one new way for the non-operation treatment of femoral head necrosis.

The invention discloses a traditional Chinese medicine preparation for treating femoral head necrosis and a preparation method thereof. The traditional Chinese medicine preparation comprises the following components in parts by weight: 10-20 parts of angelica, 10-20 parts of rhizoma ligustici wallichii, 10-15 parts of red peony root, 10-15 parts of white peony root, 10-12 parts of prepared rehmannia root, 10-12 parts of safflower, 10-15 parts of radix achyranthis bidentatae, 1-6 parts of radix aconiti, 10-15 parts of Chinese dodder seed, 10-15 parts of radix codonopsis pilosulae, 10-30 parts of astragalus root, 10-15 parts of radix dipsaci from Sichuan of China, 10-15 parts of corydalis tuber, 2-5 parts of centipede, 1-10 parts of deerhorn gelatin and 1-10 parts of licorice. The invention adopts traditional Chinese medicines which have the functions of tonifying the kidney, strengthening bone, promoting blood circulation and relieving the stasis of blood and have a certain curative effect to the femoral head necrosis, improves the blood supply dysfunction of the local artery of the femoral head necrosis, reinforces the local blood flow, promotes the regenerative formation of bone trabecula, reduces the saccular change, enhances the bone absorption, restores a cartilage position, smoothes blood vessels and recovers muscular atrophy.

The invention discloses an oral powder and an external plaster that are used for treating hyperosteogeny and rheumatoid arthritis and a preparation method thereof. The internal medicine comprises astragalus, codonopsis, Indian bread, glycyrrhiza, angelica, radix paeoniae alba, prepared rhizome of rehmannia, rhizoma chuanxiong, achyranthis bidentatae, eucommia, radix dipsaci, radix angelicae pubescentis, asarum, gentiana macrophylla, radix saposhnikoviae, dried ginger and musk, wherein, all the herbs except the musk are selected according to the required weight and crushed into powder; the musk is added into the powder; and the oral powder is obtained by blending evenly. The external medicine comprises the internal medicine materials, appropriate amount of beeswax and balm, wherein, the internal medicine materials except the musk are shredded and immersed in oil for 36 days and decocted and deslagged; medicinal oil is obtained; the beeswax and musk are added into the medicinal oil; and the external plaster is obtained by stirring and cooling. The external plaster is applied to the lesion by spreading on a black cloth. The invention is characterized by reinforcing both qi and blood, nourishing the liver and kidney, strengthening the bones and muscles, dredging the channels and collaterals, and is suitable for treating diseases in various parts of the human body, such as hyperosteogeny, rheumatoid arthritis, ankylosing spondylitis, femoral head necrosis.

The invention relates to the field of stem cells, and discloses a stem cell preparation as well as a preparation method and an application thereof. The stem cell preparation comprises adipose derived stem cells and is wide in source, high in in-vitro differentiation capacity, high in safety and good in treatment effect. The stem cell preparation also comprises high-concentration platelet-rich plasma, so that the activity of the adipose derived stem cells in the preparation can be improved, and the treatment of the adipose derived stem cells on femoral head necrosis can be promoted. The preparation method is short in preparation time and applicable to the mass production. The stem cell preparation can promote the activity of the bone cells and is favorable for the generation of new bones and capable of enhancing the VEGF expression and enhancing the generation of local necrotic blood vessels, a complete blood vessel net is formed, and the stem cell preparation can be used for preparing a drug for treating the femoral head necrosis.

The invention discloses a supporting device for the treatment of femoral head necrosis, and the device comprises a supporting apparatus and a bone fracture plate. The supporting apparatus comprises a head part, a body part, and a tail part. The head part is a bent hemisphere with gyrus, and the body part is cylindrical. The head part, the body part and the tail part are connected to form a body, and the interior of the body is hollow. The walls of the head part and the body part are provided with a plurality of hexagonal hollow-out through holes, and the inner walls of the tail part and the body part are provided with a mesh support. A hollow pipe of the body part extends outwards from the tail part. The bone fracture plate is matched with a femur, and is provided with a sleeve. During an operation, a necrotic bone tissue is removed at first, so as to place the supporting apparatus. The hollow pipe extends to the interior of the sleeve of the bone fracture plate, and bone putty is injected in the mesh support. A flow guide cable is buried in the hollow inner cavity of the supporting apparatus. The device improves the fixing of the bone fracture plate, enables a patient to bear a load and recover in advance, and achieves the treatment of femoral head necrosis from the pathology of blood supply improvement and the reduction of bone core pressure.