The invention discloses a fluridone and oxyfluorfen contained weedicidal composition and the application thereof. The fluridone and oxyfluorfen contained weedicidal composition comprises fluridone asa first active component, oxyfluorfen as a second active component and an auxiliary agent, wherein the weight ratio of the first active component to the second active component is 1:20 to 20:1, preferably 1:10 to 10:1. The fluridone and oxyfluorfen contained weedicidal composition can be prepared into missible oil, an aqueous emulsion, a suspension, a microcapsule suspension, water-dispersible granules and a dispersible oil suspension which are agriculturally acceptable. The fluridone and oxyfluorfen contained weedicidal composition is reasonable in components, good in weedicidal effect and low in using cost; the activity and the weedicidal effect of the fluridone and oxyfluorfen contained weedicidal composition are not simple superposition of the activities of the components; compared with the existing single agent, the fluridone and oxyfluorfen contained weedicidal composition has the advantages of an obvious weedicidal synergistic effect, low dosage and high crop safety; the fluridone and oxyfluorfen contained weedicidal composition has a very good control effect on grassy weeds such as digitaria sanguinalis, eleusine indica, barnyard grass, green bristlegrass, wild oat grass, bromegrass and bluegrass, and broad-leaved weeds such as glaucum, solanum nigrum, amaranthus retroflexus, purslane, convolvulus arvensis, persicaria lapathifolia, abutilon theophrasti, cocklebur, dayflower, sisymbrium sophia and capsella bursa-pastoris.