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34 results about "Atopy" patented technology
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Atopy is a predisposition toward developing certain allergic hypersensitivity reactions. Atopy may have a hereditary component, although contact with the allergen or irritant must occur before the hypersensitivity reaction can develop. Maternal psychological trauma in utero may also be a strong indicator for development of atopy.
Method of treatment of th2-mediated conditions using optimized Anti-cd30 antibodies
A method of treating Th2-mediated conditions, e.g., atopic conditions, e.g., atopic asthma and / or atopic dermatitis, using effective amount of an antibody that targets CD30, where the antibody has at least one modification relative to a parent antibody and the antibody binds with altered affinity to an FcγR or alters effector function as compared to the parent antibody.
Owner:XENCOR
T cell regulatory genes associated with immune disease
InactiveUS20050095593A1Diminish and terminate immunological disorderAvoid developmentImmunoglobulin superfamilySugar derivativesInflammatory Bowel DiseasesAutoimmune responses
A genetic locus and corresponding family of proteins associated with regulation of immune development, function, and cell survival are provided. The locus comprising the TIM family is genetically associated with immune dysfunction, including atopy, autoimmunity, inflammatory bowel disease, dysplasia, and susceptibility to blood-bourne infectious diseases. Polymorphisms in the human TIM-1 gene and exposure to Hepatitis A Virus (HAV) are shown to be associated with protection from the development of atopy.
Owner:THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIV +1
T cell regulatory genes associated with immune disease
Owner:THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIV +1
Method for detecting potato virus and viroid by once composite PCR reaction
InactiveCN101096702ALarge capacityGreat practicabilityMicrobiological testing/measurementAtopyPotato virus Y PVY
The invention discloses a detecting technique of potato virus and viroid molecule and atopic primer, which is characterized by the following: detecting four potato viruses (PVX, PVY, PLRV and PVS)and one potato viroid (PSTV)through once compound PCR; improving the atopy and detecting efficiency with low cost.
Owner:HUAZHONG AGRI UNIV
Atopy cure baby dry milk with green tea and lactobacillus
InactiveUS20100215627A1Easy extractionHigh water temperatureBiocideMilk preparationSide effectAnimal science
Provided is a prevention and treatment of baby atopy using green tea and lactobacillus digestives. By addition of 0.02˜1.3 wt % of green tea, and for the purpose of preventing side effects from green tea and increasing curative efficacy, addition of 0.15˜10 wt % (0.009˜0.8 wt % on pure lactobacillus basis) of lactobacillus digestives made up of lactobacillus or butyric-acid bacteria or yeast fungi to baby dry milk or weaning food, we can prevent and treat baby atopy. 0.1˜1.3 wt % of green tea content is adequate for the cure of babies' atopy and 0.02˜0.1 wt % of green tea content is adequate for the prevention and aftercare of baby atopy. Green tea or green tea extract and lactobacillus digestives are added during manufacturing process of the baby dry milk or weaning food.
Owner:LIM BYUNG YUN +2
Peptide having antimicrobial or Anti-inflammatory activity and pharmaceutical composition containing same as an active ingredient
The present invention relates to a peptide having antibacterial or anti-inflammatory activity and a pharmaceutical composition containing the same as an active ingredient, and more particularly to a peptide having antibacterial or anti-inflammatory activity against dental bacteria, including periodontal pathogens, and bacteria causing atopic dermatitis, and to a pharmaceutical composition containing the peptide as an active ingredient. The inventive peptide having antibacterial or anti-inflammatory activity can be used for the treatment of both dental infectious diseases, including periodontitis or peri-implantitis, and inflammations, including atopy, psoriasis or arthritis.
Owner:NANO INTELLIGENT BIOMEDICAL ENG
Methods, compositions and kits relating to chitinases and chitinase-like molecules and inflammatory disease
Owner:YALE UNIV
Daphne genkwa extracts, and pharmaceutical composition containing fractions of the extracts or compounds separated from the extracts as active ingredients for preventing or treating atopic dermatitis
ActiveUS20140072664A1Suppress atopyIncrease cytokine secretionBiocideOrganic active ingredientsAtopyMedicine
The present invention relates to a pharmaceutical composition for the prevention or treatment of atopy comprising the extract of Daphne genkwa, the fraction thereof, of the compound isolated from the same as an active ingredient. More precisely, the extract of Daphne genkwa, the fraction thereof, or the compound isolated from the same, genekwadapnin or yuanhuacine, of the present invention can increase the secretion of cytokine in Th1 immune cells and suppress atopy in the atopy mouse model, so that the extract of Daphne genkwa, the fraction thereof, or the compound isolated from the same of the present invention can be effectively used for the prevention or treatment of atopy.
Owner:KOREA RES INST OF BIOSCI & BIOTECH
Pharmaceutical composition for treatment of atopy containing exosomes derived from neural stem cells
InactiveUS20200215118A1Effective treatmentCosmetic preparationsPeptide/protein ingredientsAtopyPharmaceutical drug
The present invention relates to a pharmaceutical composition for treating atopy, which contains, as an active ingredient, neural stem cell-derived exosomes or a neural stem cell-conditioned medium containing neural stem cell-derived exosomes, and a method of treating atopy by administering the composition.
Owner:KOREA UNIV RES & BUSINESS FOUND
Composition For Diagnosing Skin Damage Caused By Fine Dust, And Composition Comprising Galangin As Active Ingredient
ActiveCN107801402AEasily damagedEnhanced barrierCosmetic preparationsCompound screeningDiseaseBULK ACTIVE INGREDIENT
The present specification discloses a biomarker for diagnosing skin cell damage caused by fine dust, a kit using the same, and a novel use of a composition comprising galangin as an active ingredient.Specifically, it is possible to conveniently check skin damage caused by fine dust by measuring and comparing the expression amounts of the biomarker in normal cells and cells damaged by fine dust. In addition, a composition of the present invention comprising galangin, an isomer thereof, a pharmaceutically acceptable salt thereof, a prodrug thereof, a hydrate thereof or a solvate thereof as an active ingredient can normalize the gene expression of skin damaged by fine dust and promote differentiation of skin keratinocytes, thereby having a skin moisturizing or skin-barrier strengthening effect. Accordingly, since the composition can be used to prevent, treat, or alleviate skin diseases such as atopy, psoriasis, etc. the composition is useful.
Owner:AMOREPACIFIC CORP
Composition for atopy or psoriasis treatment comprising liquid type plasma
ActiveUS20200179709A1Avoid hypersensitivityAvoid generatingElectrotherapyElectric discharge tubesAtopyPharmaceutical drug
Provided is a composition for atopy or psoriasis treatment including a liquid type plasma. More particularly, provided is a method for producing a liquid type plasma for preventing or treating atopic dermatitis or psoriasis, a pharmaceutical composition for preventing or treating atopic dermatitis or psoriasis using a liquid type plasma produced according to the method, and a method for preventing or treating atopic dermatitis or psoriasis using the liquid type plasma.
Owner:AJOU UNIV IND ACADEMIC COOP FOUND
Genetic susceptibility genes for asthma and atopy and asthma-related and atopic-related phenotypes
The present invention is directed to a method for diagnosing a subject as being or having a predisposition to being asthmatic. The present invention is also directed to methods of detecting whether a subject may be atopic by screening for genetic risk factors.
Owner:DUKE UNIV
Topical compositions comprising telmesteine for treating dermatological disorders
This invention relates to topical compositions, such as creams and lotions, that comprise or consist essentially of Telmesteine, or a pharmaceutically acceptable salt thereof, as the active ingredient, and methods for their use in treating a variety of dermatological diseases and disorders, including atopic, dermatitis (eczema), allergic contact dermatitis, seborrheic dermatitis, radiation dermatitis, psoriasis, xerosis and atopy.
Owner:SINCLAIR PHARMA
Novel autophagy activation-induced compound for improving skin inflammation for aging
ActiveUS20190160033A1High expressionCell protectiveCosmetic preparationsOrganic active ingredientsDiseaseAtopy
Provided are a novel autophagy activation-inducing compound or salt thereof, and a use thereof, and particularly, a medicinal composition for treatment and prevention of neurodegenerative diseases, type II diabetes, or atopy or psoriasis dermatitis, a cosmetic composition for alleviation of aging or atopy or psoriasis dermatitis, and a food composition, including the compound capable of inducing autophagy activation or a pharmaceutically acceptable salt thereof.
Owner:INCOSPHARM CORP
Ointment
InactiveUS20080167379A1Good storage stabilityLow skin irritancyBiocideElcosanoid active ingredientsMedicinal chemistrySkin irritant
An ointment containing a compound represented by formula (I):[wherein R1 represents any group ofa group represented by the formula:—(CH2)4—S—CH2—CO2H,a group represented by the formula:—(CH2)4—S—CH2—CO2CH3,a group represented by the formula:—(CH2)4—C≡C—CO2H,a group represented by the formula:—CH2—S—(CH2)2—S—CH2—CO2H, anda group represented by the formula:—CH2—S—(CH2)4—CO2H],and an oleaginous base, is an ointment containing a compound which is effective for atopic symptoms, and is an ointment having low skin irritancy and excellent storage stability, thus, can be used as a pharmaceutical product effective for the pruritus caused by atopy or the like.
Owner:TAISHO PHARMACEUTICAL CO LTD
Methods, compositions and kits relating to chitinases and chitinase-like molecules and inflammatory disease
The present invention includes compositions and methods for the treatment of inflammatory disease (e.g., asthma, COPD, inflammatory bowel disease, atopic dermatitis, atopy, allergy, allergic rhinitis, scleroderma, and the like), relating to inhibiting a chitinase-like molecule. The invention further includes methods to identify new compounds for the treatment of inflammatory disease, including, but not limited to, asthma, COPD and the like. This is because the present invention demonstrates, for the first time, that expression of IL-13, and of a chitinase-like molecule, mediates and / or is associated with inflammatory disease and that inhibiting the chitinase-like molecule treats and even prevents, the disease. Thus, the invention relates to the novel discovery that inhibiting a chitinase-like molecule treats and prevents an inflammatory disease.
Owner:YALE UNIV
Composition for diagnosing skin damage caused by fine dust, and composition comprising galangin as active ingredient
InactiveUS20180044734A1Convenient and quick diagnosisEasy screeningOrganic active ingredientsCompound screeningPharmaceutical medicineBULK ACTIVE INGREDIENT
The present specification discloses a biomarker for diagnosing skin cell damage caused by fine dust, a kit using the same, and a novel use of a composition comprising galangin as an active ingredient. Specifically, it is possible to conveniently check skin damage caused by fine dust by measuring and comparing the expression amounts of the biomarker in normal cells and cells damaged by fine dust. In addition, a composition of the present invention comprising galangin, an isomer thereof, a pharmaceutically acceptable salt thereof, a prodrug thereof, a hydrate thereof or a solvate thereof as an active ingredient can normalize the gene expression of skin damaged by fine dust and promote differentiation of skin keratinocytes, thereby having a skin moisturizing or skin-barrier strengthening effect. Accordingly, since the composition can be used to prevent, treat, or alleviate skin diseases such as atopy, psoriasis, etc. the composition is useful.
Owner:AMOREPACIFIC CORP
Biological dataset profiling of asthma and atopy
Methods and systems for evaluating biological dataset profiles relating to asthma and other atopic conditions are provided, where datasets comprising information for multiple cellular parameters are compared and identified, and used in the evaluation of candidate pharmacologic agents for suitability as therapeutic agents.
Owner:DISCOVERYX CORP
Pharmaceutical or cosmetic composition containing nicotinic acid adenine dinucleotide phosphate or derivative thereof
InactiveUS20130137177A1Increase skin hydrationPromote differentiationOrganic active ingredientsCosmetic preparationsDiseaseNanostructure
Provided are a method of preparing a zinc oxide nanostructure electrode and a method of preparing a dye-sensitized solar cell using the same.The present invention relates to a use of nicotinic acid adenine dinucleotide phosphate or a derivative thereof for promoting the differentiation of keratinocytes into fibroblasts. The present invention provides a pharmaceutical or cosmetic use of a composition containing NAADP or a derivative thereof for regenerating and improving a skin barrier, or preventing, improving or treating stratum corneum disorders such as psoriasis or atopy, and a use for promoting the differentiation of separated keratinocytes.
Owner:LABIO CO LTD
Vitamin d compounds and methods of using the same
The present disclosure provides a composition comprising a first amount of a Vitamin D compound and a second amount of a probiotic compound. The disclosure also provides a method of treating an atopic condition in a subject in need thereof comprising administering to the subject a therapeutically effective amount of the composition detailed herein.
Owner:ALLERGYINTELLECT INC
Tetrahydropyran heterocyclic cyclopentyl heteroaryl modulators of chemokine receptor activity
The present invention is further directed to compounds of the formulas: (I) (II) (wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R15, R16, R17, R18, R19, R24 and R25 are as defined herein) which are modulators of chemokine receptor activity and are useful in the prevention or treatment of certain inflammatory and immunoregulatory disorders and diseases, allergic diseases, atopic conditions including allergic rhinitis, dermatitis, conjunctivitis, and asthma, as well as autoimmune pathologies such as rheumatoid arthritis and atherosclerosis. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which chemokine receptors are involved.
Owner:MERCK & CO INC
Pharmaceutical composition comprising purple corn extract for prevention or treatment of skin disease
InactiveUS20190282650A1Prevent skinEffective preventionOrganic active ingredientsPowder deliveryDiseasePrurigo
Disclosed are a pharmaceutical composition for preventing or treating a skin disease containing a purple corn extract, and more particularly, to a pharmaceutical composition for preventing or treating a skin disease containing a purple corn extract that has a potent effect of preventing or treating at least one skin disease selected from the group consisting of atopy, psoriasis, eczema, keratosis, prurigo and warts, using the purple corn extract.
Owner:FRONTBIO
Antibacterial, deodorization, easing of acne and atopy or skin calming-functional composition for y-zone cleanliness containing quercus acutissima sap and zinc ricinoleate
PendingUS20220047494A1Provide effectEasy to deodorizeCosmetic preparationsToilet preparationsZinc ricinoleateAtopy
The present invention relates to an antibacterial, deodorization, easing of acne and atopic dermatitis, or skin calming-functional composition for Y-zone cleanliness containing Quercus acutissima sap, wherein the composition for Y-zone cleanliness is a composition used for cleaning a Y zone of women, which contains Quercus acutissima sap to provide antibacterial and deodorizing effects and to alleviate acne and atopic dermatitis or to provide a skin-calming function.
Owner:MEDICLASSIC CO LTD
Poly (epsilon-caprolactone-co-methylmethacrylate), method for preparing the same using super critical fluid, and method for preparing therapeutic agent for skin diseases such as acne, atopy and athlete's foot comprising the same
A biodegradable polymer comprising a spherical poly (ε-caprolactone-co-methylmethacrylate) used in a therapeutic agent for skin diseases and a method for preparing the same, and a method for preparing the therapeutic agent for skin diseases having the particle size of 50 to 100 nm and a spherical shape comprising the poly (ε-caprolactone-co-methylmethacrylate) and salicylic acid.
Owner:SEOUL NAT UNIV R&DB FOUND
Pharmaceutical composition comprising purple corn extract for prevention or treatment of skin disease
InactiveUS20210346455A1Prevent skinEffective preventionOrganic active ingredientsPowder deliveryPrurigoDisease
Disclosed are a pharmaceutical composition for preventing or treating a skin disease containing a purple corn extract, and more particularly, to a pharmaceutical composition for preventing or treating a skin disease containing a purple corn extract that has a potent effect of preventing or treating at least one skin disease selected from the group consisting of atopy, psoriasis, eczema, keratosis, prurigo and warts, using the purple corn extract.
Owner:FRONTBIO
Lactobacillus paracasei NCC2461 (ST11) for use by perinatal maternal administration in the reduction and prevention of allergies in progeny
InactiveCN103826648ABacteria material medical ingredientsImmunological disordersAtopyHypersensitive response
The present invention provides a probiotic, Lactobacillus paracasei NCC 2461, i.e. ST11, for use by administration to expectant females and / or lactating mothers, and to their progeny for the reduction or prevention of the development of allergic immune responses in progeny. A daily dose of ST11 is administered to a pregnant woman for at least two weeks before delivery and, after delivery, the daily dose of ST11, is administered to the lactating mother or the newborn infant for at least two months, either directly or via the mother's milk. The infant immune responses to allergens are thus reduced, resulting in a "dampened" allergic response. Thus allergy, including atopy, may be prevented in the progeny.
Owner:NESTEC SA
Methods and compositions relating to epoxide hydrolase genes
PendingUS20200407796A1Reduce the possibilityReduce developmentMedical data miningHealth-index calculationHydrolase GeneAtopy
Owner:RGT UNIV OF CALIFORNIA
Autophagy activation-induced compound for improving skin inflammation for aging
ActiveUS10617662B2Effective in treatment and preventionOrganic active ingredientsCosmetic preparationsNeuro-degenerative diseasePharmaceutical medicine
Provided are a novel autophagy activation-inducing compound or salt thereof, and a use thereof, and particularly, a medicinal composition for treatment and prevention of neurodegenerative diseases, type II diabetes, or atopy or psoriasis dermatitis, a cosmetic composition for alleviation of aging or atopy or psoriasis dermatitis, and a food composition, including the compound capable of inducing autophagy activation or a pharmaceutically acceptable salt thereof.
Owner:INCOSPHARM CORP
Composition for treating atopy or pruritus comprising n-acetyl or n-acyl amino acid
PendingUS20220233485A1Less side effectsPreventing and improving and treating atopyCosmetic preparationsOrganic active ingredientsSide effectAtopy
The present disclosure relates to a composition for preventing, alleviating or treating pruritus and / or atopy using an N-acetylamino acid or an N-acylamino acid having almost no side effects on the human body. Also, the present disclosure relates to a cosmetic composition for moisturizing skin or soothing skin. The composition of the present disclosure may be utilized to ameliorate a problematic skin condition caused by various causes, or to safely and effectively alleviate or treat pruritus and / or atopy without concern about side effects.
Owner:STEMDR +2
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