52results about How to "Increase skin hydration" patented technology

Transcutaneous immunization can deliver antigen to the immune system through the stratum corneum without physical or chemical penetration to the dermis layer of the skin. This delivery system induces an antigen-specific immune response. Use of skin-active adjuvants is preferred. Although perforation of intact skin is not required, superficial penetration or micropenetration of the skin can act as an enhancer; similarly, hydration may enhance the immune response. This system can induce antigen-specific immune effectors after epicutaneous application of a formulation containing one or more antigen and adjuvant. The formulation may initiate processes such as antigen uptake, processing, and presentation; Langerhans cell activation, migration from the skin to other immune organs, and differentiation to mature dendritic cells; contacting antigen with lymphocytes bearing cognate antigen receptors on the cell surface and their stimulation; and combinations thereof. Systemic and / or regional immunity may be induced; immune responses that result in prophylaxis and / or therapeutic treatments are preferred. Antigen and adjuvant activities in the formulation may be found in the same molecule, two or more different molecules dissociated from each other, or multiple molecules in a complex formed by covalent or non-covalent bonds. For antigens and adjuvants which are proteinaceous, they may be provided in the formulation as a polynucleotide for transcutaneous genetic immunization. Besides simple application of a liquid formulation, patches or other medical devices may be used to deliver antigen for immunization.

This invention provides compositions and methods of manufacturing such compositions that employ GRAS compounds which can act to promote the generation of stem, epidermal or other skin cells in the epidermis, activation of collagen synthesis, activation of hyaluronic acid synthesis, enhanced skin hydration, and dermal healing by stimulating stem cell and fibroblast migration to sites of needed repair. These compositions and methods are useful for rejuvenating the skin and for treating some skin-related aging or other dermal damaging conditions, including wrinkle reduction and treatment of minor dermal wounds.

An improved composition for treatment of the skin comprises: (1) methionine and cysteine in a quantity sufficient to accelerate restoration of the integrity and fullness of the skin; (2) a mixture of essential amino acids in a quantity sufficient to accelerate restoration of the integrity and fullness of the skin, the mixture comprising isoleucine, leucine, lysine, phenylalanine, threonine, tryptophan, valine, histidine, and arginine; (3) at least one antioxidant in a quantity sufficient to accelerate restoration of the integrity and fullness of the skin; (4) at least one cross-linking agent in a quantity sufficient to accelerate restoration of the integrity and fullness of the skin; (5) at least one metallic catalyst in a quantity sufficient to accelerate restoration of the integrity and fullness of the skin; (6) at least one transepidermal delivery agent in a quantity sufficient to promote delivery of the composition to the skin; and (7) a topical pharmaceutically acceptable carrier. The antioxidant can be ascorbic acid. The cross-linking agent can be proanthocyanidin or silybin. The metallic catalyst can be Cu (II) in a suitable cupric salt. The transepidermal delivery agent can be benzyl alcohol.

The invention relates to a cosmetic and / or pharmaceutical composition comprising, in a physiologically suitable medium, a carob peptide extract (Ceratonia siliqua L.) as an active agent for promoting aquaporin expression. The present invention also relates to the use of a carob peptide extract (Ceratonia siliqua L.), as an active agent for promoting aquaporin expression, in a cosmetic composition for improving the moisturization and the barrier function of the epidermis and for stimulating skin regeneration. The invention also relates to the use of this novel active agent for preparing a pharmaceutical, in particular dermatological, composition for regulating and / or stimulating aquaporin activity. The invention also relates to a cosmetic treatment method for preventing or combating dryness of the skin and mucous membranes and the manifestations of skin aging.

The invention relates to aloe moisturizing lotion. The aloe moisturizing lotion consists of the components of active substances and a matrix, wherein the active substances include aloe gel freeze-dried powder, oat glucan and sodium hyaluronate. The aloe moisturizing lotion disclosed by the invention has dual effects of moistening the surface layer, moisturizing the corium layer and improving a barrier function of the skin, can promote the water metabolism and circulation of the skin, prevents the xerosis and winkles of the skin, and prevents the premature senility of the skin.

Compositions, devices and methods for improving the aesthetic appearance of skin are described. In one embodiment, the compositions, devices and methods reduce fine lines and / or wrinkles, and in other embodiment, the compositions, devices and methods improve skin tone by reducing regions of hyperpigmentation. The cosmetic compositions and devices described are formulated for topical application for extended wear, and comprise one or more agents to achieve the desired beneficial effect. The composition is preferably an adhesive composition that is secured to the skin for an extended time for sustained release of the one or more beneficial agents.

The present invention relates generally to methods of use and compositions useful for treating skin. The composition includes a combination of one or more of Butyrospermum parkii (shea butter), PEG-50 shea butter, glycerin, Helianthus annuus (sunflower) seed oil, Prunus armeniaca (apricot) kernel oil, acrylates copolymer, sodium lauryl sulfate, lauramidopropyl betaine, sodium methyl cocoyl taurate, glycerin, and polyquaternium-7.

Electrolytic acid or alkaline water having a NMR half line width using 17O of from about 45 to less than 51 Hz, and an oxide reduction potential of from −1000 to +200 mV, or from +600 to +1300 mV, topical compositions that contain such water, uses for such water to hydrate skin, deliver drugs and treat various skin and mucosal conditions, and methods and apparatus for manufacturing the water.

Described herein are various natural ingredients for skin-related applications. Individual compounds provide beneficial effects for improved collagen production, fibroblast proliferation, antioxidant protection and free radical inhibition. Combinations of these individual compounds exhibit synergistic effects, leading to dramatic improvements in skin moisture levels, wrinkle reduction, and elasticity. Various examples of combined ingredients are provided, which can be applied in methods related to conditioning the skin, and in cosmetic formulations for improved aesthetic appearance.

A sprayable film-forming pharmaceutical composition for dermal application comprises at least one therapeutically active ingredient dissolved in a pharmaceutically acceptable propellant selected from the group consisting of dimethyl ether, diethyl ether and methylethylether, and a mixture of dimethyl ether, diethylether and methylethyl ether, and a second propellant selected from C3-5 alkanes, hydrofluoroalkanes, hydrochloroalkanes, fluoroalkanes and chlorofluoroalkanes, the propellant being present in an amount of 50-99.5% w / w of the composition, the composition further comprising a film-forming polymer, a plasticizer and an oily release-enhancing agent.

Disclosed herein in some embodiments are compositions and methods for treating or cosmetically addressing skin conditions. In certain embodiments, the compositions utilize optically transparent carriers and are capable of dissolving hydrophilic and hydrophobic active ingredients. In an embodiment, the compositions comprise a volatile silicone, an organic alcohol, and a diester. In another embodiment, the compositions comprise a volatile silicone, specially-denatured ethanol, and diisopropyl sebacate. In another embodiment, the volatile silicone comprises a mixture of octamethyltrisiloxane and dimethicone. In other embodiments, the compositions are used to treat skin conditions. Methods of treating or improving skin firmness, skin hydration, skin wrinkles and fine lines, and skin clarity, among other methods, are disclosed.

The invention relates to a liquid skin-cleansing composition. The liquid skin-cleansing composition is prepared from the following raw materials in parts by weight: 3.0-15.0 parts of natural grease, 18.0-27.0 parts of fatty acid, 6.0-8.0 parts of potassium hydroxide, 0.2-3.0 parts of a non-ionic surfactant, 0.1-3.0 parts of brown sugar, 1.0-5.0 parts of potassium cocoyl hydrolyzed avenin, and 50.0-60.0 parts of water; and the non-ionic surfactant is a composition of PEG / PPG-80 / 20 copolymers, PEG-32 and PEG-6. The liquid skin-cleansing composition is low in viscosity and is conveniently taken for use, and the liquid skin-cleansing composition is added into cleaning products and is easy to rinse, the dry and tight body feeling is avoided, rich foam can be formed, and the foam amount of the liquid skin-cleansing composition is not affected even if the liquid skin-cleansing composition is used in hard water.

The invention discloses a preparation method of a lycopene-rich yeast extract. The method is characterized by comprising the following steps of (1) bacterial strain activation; (2) seed liquid preparation; (3) liquid state fermentation; (4) yeast extract obtaining. The lycopene-rich yeast extract is prepared through the specific technological processes such as bacterial strain activation, seed liquid preparation, liquid fermentation and enzymic digestion synergistic microwave crushing methods; rich yeast nutrition active substances such as small molecule peptide, free amino acid, vitamin, nucleic acid and nucleotide are contained; the nutrition performance of yeast degradation substances and the antioxidation performance of lycopene are realized; good cosmetic development values are realized.

The invention discloses a formula of donkey-hide gelatin paste with effects of strengthening primordial qi and a preparation process of the donkey-hide gelatin paste and relates to the technical field of food and health food preparation. The formula comprises 30% of donkey-hide gelatin, 20% of walnut kernels, 20% of black sesames, 10% of yellow rice wine, 9.7% of rock sugar, 4% of maltodextrin, 5% of dried pipefish, 0.3% of sodium ferric EDTA, 0.5% of Lepidium meyenii Walp and 0.5% of soy isoflavone. The preparation process comprises cleaning selected walnut kernels, black sesames and dried pipefish, baking the cleaned materials for next use, putting donkey-hide gelatin, rock sugar, maltodextrin and yellow rice wine into an electric heating jacketed kettle, carrying out constant temperature boiling, adding sodium ferric EDTA, Lepidium meyenii Walp and soy isoflavone into the electric heating jacketed kettle, carrying out high temperature boiling, pouring the dried walnut kernels, black sesames and dried pipefish into the molten donkey-hide gelatin liquid, carrying out uniform isothermal stirring, putting the mixture into a mold, carrying out cooling, cutting the molded material to obtain small pieces and carrying out packaging. The donkey-hide gelatin paste with effects of strengthening primordial qi can be used by a plurality of people, has general performances and a reasonable price and is suitable for promotion.

A composition for strengthening skin barrier or improving skin barrier function is able to improve objective indicators related to the protection of skin barrier, the strengthening of skin barrier, and / or the improvement of skin barrier function. The composition exhibits the effects of increasing the amount of ceramides, dihydroceramides and sphingoid bases, increasing the activities of enzymes that are involved in the synthesis thereof, and decreasing the activities of enzymes that are involved in the degradation thereof. In addition, the composition is able to restore skin barrier function by reducing TSLP, IL-4, and IL-13 which are closely associated with skin barrier damage, and thus interrupting a vicious circle in which the lipids and proteins contributing to skin barrier decrease.

A cosmetic composition for whitening skin and a preparation method thereof The composition comprises the following components: pearl powder, pearl extract, glycyrrhiza glabra aqueous solution, hydrolyzed conchiolin protein and pea extract. The contents of the pearl powder and the pearl extract are not both zero, and the glycyrrhiza glabra aqueous solution contains 0.5 to 5.0% of the glycyrrhiza glabra extract.

The present application is directed, generally, to an array of products and methods for treating periorbital dyschromia. More specifically, the present application discloses an array of products and methods for treating different types of periorbital dyschromia. The products and methods utilize extracts of Cucurbita pepo.

The present invention provides a method of enhancing hyaluronic acid secretion in a subject, which comprises administrating a composition containing of Streptococcus thermophilus DSM 28121 to the subject, and the hyaluronic acid content in the blood of the subject is increased. The present invention further provides a novel probiotic strain which is Streptococcus thermophilus DSM 28121, which has the ability to survive and colonize in the intestine of the subject to increase the number.

Solid cleansing compositions and methods for the same are disclosed herein. The solid cleansing compositions may include a soap, a plant oil, and a hydrolyzed protein. The plant oil and the hydrolyzed protein may be present in an effective amount to maintain or increase hydration of skin. The plant oil may be or include a flaxseed oil, and the hydrolyzed protein may be or include a hydrolyzed milk protein.

A compound of formula (I) R1-Wm-Xn-AA1-AA2-AA3-AA4-AA5-AA6-AA7-AA8-AA9-Yp-Zq-R2, wherein AA1 is Phe; AA2 is Trp; AA3 is selected from Met, Leu and Ile; AA4 is selected from Lys, Arg and Gln; AA5 is Arg; AA6 is Lys; AA7 is selected from Arg, Lys and His; AA8 is selected from Val, Ile, Leu and Met; and AA9 is Pro. The compound is useful in the treatment and / or care of the skin, hair, nails and / or mucous membranes, in particular for improving the barrier function of the skin, for energizing the skin and as an anti-aging agent.

A film-forming pharmaceutical composition for dermal application comprises at least one therapeutically active ingredient dissolved in a volatile solvent, the composition further comprising a film-forming polymer, a plasticizer and an oily release-enhancing agent. The composition is capable of forming, after application on skin and evaporation of the solvent, a continuous phase comprising the film-forming polymer and the plasticizer and a dispersed phase comprising droplets of the oily release-enhancing agent.

A cosmetic composition suitable for topical application is provided. The cosmetic composition comprises: a safe and effective amount of a humectant; a safe and effective amount of a lipid bilayer structurant, and a safe and effective amount of a chaotropic agent. The chaotropic agent denatures the cross-linked proteinaceous layer sitting immediately above skin thereby increasing the amount of humectant and lipid bilayer structurant that enters the stratum corneum; the humectant binds together with water molecules and the lipid bilayer structurant knits together the lipid bilayers of the stratum corneum thereby preventing water loss.

The present invention describes a topical cosmetic composition comprising a combination of raw Fevillea trilobata seed oil, trehalose, sodium hyaluronate, betaine and cosmetically acceptable excipients, and also the use thereof to moisturize the skin and to maintain the microbiota of the skin. The present invention pertains to the field of cosmetic science, and more specifically relates to cosmetic preparations for treating the skin.

This invention relates to benzoyl peroxide products for skin treatment, and more particularly to a kit containing a benzoyl peroxide product and a topical moisturizing product. In one embodiment the kit contains BenzaClin® brand clindamycin-benzoyl peroxide gel and Viscontour® brand hyaluronic acid serum.

Uses are described for hemolymph, contents of hemolymph, fragments or components of the contents found within hemolymph, including hemocyanin, any of which may be derived from crustaceans, as functional agents to treat diseases, provide symptomatic relief, provide a beautifying or relieving effect to the intended organ or site-of-intended-use, or be used as an ingredient in formulations designed to aid in the relief of pathologies or states commonly associated with inflammation and dry skin, including, but not limited to eczema, dermatitis, psoriasis, cystitis, asthma, sinusitis, joint pain, as well as other instances of acute and chronic inflammation, and for relief of general symptoms that may be associated with inflammation and dry skin but not linked directly in the intended use, including, but not limited to, redness, itchiness, irritation, muscle or joint fatigue, swelling, hydrating the skin, and reducing transepidermal water loss (TEWL).

The invention relates to the technical field of cosmetics, in particular to efficient moisturizing double-layer water and a preparation method thereof. The phase A comprises the following raw materials in percentage by weight: 0.01-0.5% of glucuronic acid and the balance of water; a phase B: 0.1-8% of an emulsifier, 1-10% of C15-19 alkane, 1-10% of hydrogenated polyolefin and 1-7% of vegetable oil; a phase C: 1 to 10% of small molecule polyol and 0.2 to 0.6% of p-hydroxyacetophenone; phase D: 0.001-5% of a plant extract; 0.001-2% of hyaluronic acid and a derivative thereof; and a phase E: 0.001 to 0.5 percent of essence. Compared with the prior art, the product has excellent visual and outstanding skin care effects, the moisture content of the skin is still increased by 10% or above after the product is used for 3 h compared with that before the product is used, the product is high in stability and wide in temperature resistance range, meanwhile, the product has good broad-spectrum antibacterial activity, meanwhile, the content of harmful substances meets the industrial standard, and the product is suitable for being widely popularized in the field of cosmetics.