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Clear compositions and methods for the delivery of active ingredients for skin care

A technology of active ingredients and compositions, applied in the field of skin care compositions, which can solve problems such as commercial dissatisfaction, carrier and vehicle commercial dissatisfaction, and failure to pass through the skin

Inactive Publication Date: 2017-06-13
ARBONNE INT
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the development of formulations capable of dissolving and delivering mixtures of hydrophilic and hydrophobic compounds using consumer- and patient-preferred carriers is challenging
Formulations, carriers and vehicles that do not provide solubility of hydrophobic and hydrophilic compounds in optically clear compositions may not be commercially desirable in some circumstances
Furthermore, formulations, carriers and vehicles that do not provide good penetration across the skin, especially through the stratum corneum, may also be commercially less desirable in some cases

Method used

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  • Clear compositions and methods for the delivery of active ingredients for skin care
  • Clear compositions and methods for the delivery of active ingredients for skin care
  • Clear compositions and methods for the delivery of active ingredients for skin care

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0136] Example 1: Skin care product composition

[0137] A product composition within the range specified in or with the amount specified in Formulation A in Table 1 is prepared by the following procedure, and it can also use alternative mixing, blending, homogenizing, spraying or art Relevant manufacturing procedures known to those of ordinary skill are prepared.

[0138] Table 1

[0139] Formula A

[0140]

[0141]

[0142] The composition is prepared in a stainless steel tumbler or tank using an air mixer. Cans with electrical components must not be used as they may pose an explosion risk. The bowl, air mixer, and pump should be grounded with a ground wire, and operators should wear an antistatic strap when dispensing and handling ethanol. Into a sterilized, jacketed stainless steel tank equipped with an air mixer, add the following materials in sequence with agitation: SD Ethanol 40-B, caprylic / capric triglycerides, hexylresorcinol and ethyl linoleate (ASYNTRA...

Embodiment 2

[0145] Example 2: Skin care product composition

[0146] Product compositions were prepared using the ranges specified in Formulation B in Table 2.

[0147] Table 2

[0148] Formula B

[0149]

[0150] This composition was prepared using the method described in Example 1. Additional active ingredients can be added as described in Example 1.

Embodiment 3

[0151] Example 3: Alternative Skin Care Product Compositions

[0152] Product compositions were prepared with the composition specified in Formulation C in Table 3.

[0153] table 3

[0154] Formula C

[0155]

[0156]

[0157] Prepare this composition by premixing SD Alcohol 40-B, Azelaic Acid, Mandelic Acid, Niacinamide, SYMWHITE 377, and DERM X and heating to 45-50°C until all solids dissolve. A premixed composition of DUB DIS, XIAMETER PMX-1184, BV-OSC, ASYNTRA SL, SYSTENOLA and SYMRELIEF 100 was then added to this composition. Additional active ingredients may also be added.

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PUM

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Abstract

Disclosed herein in some embodiments are compositions and methods for treating or cosmetically addressing skin conditions. In certain embodiments, the compositions utilize optically transparent carriers and are capable of dissolving hydrophilic and hydrophobic active ingredients. In an embodiment, the compositions comprise a volatile silicone, an organic alcohol, and a diester. In another embodiment, the compositions comprise a volatile silicone, specially-denatured ethanol, and diisopropyl sebacate. In another embodiment, the volatile silicone comprises a mixture of octamethyltrisiloxane and dimethicone. In other embodiments, the compositions are used to treat skin conditions. Methods of treating or improving skin firmness, skin hydration, skin wrinkles and fine lines, and skin clarity, among other methods, are disclosed.

Description

[0001] Cross References to Related Applications [0002] This application claims the benefit of US Provisional Application Serial No. 62 / 007,837, filed June 4, 2014, which is incorporated herein by reference in its entirety. [0003] field of invention [0004] In some embodiments, the present invention relates to compositions and methods useful for skin care. [0005] Background of the invention [0006] Formulations for topical delivery of active ingredients must simultaneously address multiple challenges. The impermeability of the skin is well known, with the stratum corneum acting as a barrier against pathogens and toxic environmental chemicals. The optimal formulation is likely to have the ability to dissolve a wide range of hydrophobic and hydrophilic active ingredients, enhance the penetration of active ingredients into the skin, and exhibit the best physical properties of interest to consumers, such as, for example, ideal Evaporation rate and non-greasy feel on the s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61Q19/00A61Q17/04A61K8/89
CPCA61K8/34A61K8/37A61K8/585A61K8/891A61K2800/262A61Q19/08A61K8/9789A61K8/347A61K8/362A61K8/365A61K8/4973A61K8/63A61K8/675A61K31/192A61K31/194A61K47/10A61K47/14A61K47/22A61K47/28A61K47/34A61K47/46A61Q19/00
Inventor P.马特拉弗斯
Owner ARBONNE INT
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