The invention relates to a preparation method of soap for removing wrinkles and nourishing face, which is characterized by comprising the following steps: putting 30-35g of sodium hydroxide and 80-100g of pure water into a glass beaker, stirring until the sodium hydroxide is completely dissolved to obtain an alkali solution, cooling by standing, taking 10-15g of angelica, 10-15g of white peony root and 10-15g of aconitum fischeri peichb, grinding into traditional Chinese medicine powder, adding the traditional Chinese medicine powder, 30-50g of coconut oil, 20-30g of palm oil, 40-50g of castor oil, 30-40g of olive oil, 20-30g of avocado oil, 15-30g of sweet almond oil, 40-50g of wheat germ oil and 30-40g of fructus rosae oil into a glass beaker, and heating and stirring uniformly to obtain mixed oil; and when the alkali solution and mixed oil are cooled to 45 DEG C, dropwisely adding 8-10g of pearl powder, 2-3g of plant carmine pigment and 3-5g of santalum essential oil, stirring uniformly, adding into a soap mold, cooling, drying, sterilizing and packaging to obtain the soap.