Essence containing natural astaxanthin
A technology of natural astaxanthin and astaxanthin, which is applied in the field of essence containing natural astaxanthin, can solve the problems of continuous exertion of effects, inability to give full play to skin care efficacy, and low bioavailability, so as to enhance the effect of skin care and health care , Excellent transdermal utilization rate, high skin care effect
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Embodiment 1
[0034] The preparation method of astaxanthin essence provided by the present invention comprises the following steps:
[0035] 1) Preparation of free astaxanthin:
[0036] Using Haematococcus pluvialis as the biological raw material for preparing esterified astaxanthin, weigh 1kg of Haematococcus pluvialls powder, add 10 times the weight of raw material (W / V) absolute ethanol, and repeatedly extract 2 times, each Sub-extract for 1h, combine the extracts, then concentrate the extracts under reduced pressure, remove the solvent, and obtain the crude extract; then add the crude extract to 30 times the volume of the mass concentration of 2% potassium hydroxide solution, in The saponification reaction was carried out at 4°C and filled with nitrogen. After the reaction, the reaction system was placed at -2°C for 2 hours, and then filtered to collect the crystallized purple-red substance to obtain refined free astaxanthin;
[0037] 2) Preparation of esterified astaxanthin:
[0038]...
Embodiment 2
[0047]A preparation method of astaxanthin essence, comprising the following steps:
[0048] 1) Preparation of free astaxanthin: use Haematococcus pluvialls as the biological raw material for preparing esterified astaxanthin, weigh 100g of Haematococcus pluvialls powder, add 20 times the raw material quality (W / V) of ethyl acetate to soak After extracting for 4 hours, the extract was collected by filtration, and then the extract was concentrated under reduced pressure, and the solvent was removed to obtain a crude extract. Then, homogeneously emulsify with 1 times the mass of Tween 80, and then add lipase-containing phosphate buffer, the amount of enzyme is 10U / μg total astaxanthin, the enzymatic hydrolysis conditions are 40°C, pH5.5, and the enzymatic hydrolysis time for 12h. After the enzymatic hydrolysis, add ethyl acetate to the system until the emulsion is broken, collect the oil phase, and concentrate under reduced pressure to obtain free astaxanthin;
[0049] 2) Prepar...
Embodiment 3
[0055] A preparation method of astaxanthin essence, comprising the following steps:
[0056] 1) Preparation of free astaxanthin: Weigh 100g of Haematococcus pluvialis powder, put it in the extraction kettle of a 1L supercritical extraction device, set the temperature of the extraction kettle to 40°C, the pressure to 30MPa, and the extraction agent CO 2 The flow rate is set at 20L / h, the temperature and pressure of the separation tank I are 35°C and 10MPa respectively, the temperature of the separation tank II is 40°C, and the CO 2 The flow rate of the fluid is 30L / h, the continuous dynamic extraction time is 3h, the extract is discharged from the separation tank irregularly, collected and stored in the container, the extract is a dark red viscous substance, and the crude extract is obtained; then The crude extract was added to 20 times the volume of sodium hydroxide solution with a mass concentration of 4%, and the saponification reaction was carried out at 4°C under nitrogen-...
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Description
Claims
Application Information
- IPC
- A61K8/37; A61K8/35; A61K8/11; A61K8/06; A61Q17/04; A61Q19/00; A61Q19/08
- CPC
- A61K8/35; A61K8/37; A61K8/11; A61K8/068; A61Q19/00; A61Q19/08; A61Q17/04; A61K2800/56
- Inventors
- 谷彩霞; 刘舒婷