Freeze-dried powder, solvent and application of freeze-dried powder and solvent

A technology of freeze-dried powder and solvent, which is applied to a solvent comprising a skin penetration enhancer, and the application field of the freeze-dried powder and the solvent can solve the problems of single product function, discount of skin care effect, reduced activity and the like, so as to improve skin care. Effect, good fluffy shape, long-lasting effect

Pending Publication Date: 2019-09-17
STEMIRNA THERAPEUTICS CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, most of the existing biogenetic cosmetics only contain 1 to 2 polypeptide molecules, resulting in a single product function, which cannot improve the skin condition in an all-round way
In addition, for liquid, emulsion, and slurry cosmetics, the long-term activity of some small molecular polypeptides cannot be guaranteed, and small molecular polypeptides may easily lose their activity during the preparation and storage of cosmetics and cannot exert corresponding skin care effects.
In addition, after compounding small molecule peptides with other ingredients of cosmetics, such as moisturizing ingredients and antiseptic ingredients, their activity may be reduced by the influence of these ingredients, resulting in a greatly reduced efficacy and unable to really improve the skin condition
In addition, the raw materials of many cosmetics on the market cannot really penetrate the epidermis to reach the dermis, resulting in greatly reduced skin care effects

Method used

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  • Freeze-dried powder, solvent and application of freeze-dried powder and solvent
  • Freeze-dried powder, solvent and application of freeze-dried powder and solvent
  • Freeze-dried powder, solvent and application of freeze-dried powder and solvent

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0075] Embodiment 1: A kind of cosmetic suit comprising lyophilized powder and solvent

[0076] (1) Freeze-dried powder

[0077] 1. Composition

[0078] Umbilical cord mesenchymal stem cell supernatant, acetyl hexapeptide-8, hydrolyzed sodium hyaluronate, mannitol, and water.

[0079] 2. Process

[0080] Dissolve the above ingredients in water according to the proportion, stir evenly to obtain a mixed solution, divide the mixed solution into freeze-dried bottles, vials or docking bottles, and then put it into a vacuum freeze dryer, set the pressure and freeze-dryer Drying curve, according to the setting procedure to obtain a solid powder, which is freeze-dried powder.

[0081] The freeze-dried powder formula is: umbilical cord mesenchymal stem cell supernatant 40g, mannitol 1g, hydrolyzed sodium hyaluronate 0.1g, acetyl hexapeptide-8 35g, water 23.9g.

[0082] The preparation of freeze-dried powder is carried out with reference to the general technology in this field. In...

Embodiment 2

[0094] Embodiment 2: A kind of cosmetic suit comprising lyophilized powder and solvent

[0095] (1) Freeze-dried powder

[0096] 1. Composition

[0097] Bone marrow mesenchymal stem cell supernatant, palmitoyl tripeptide-1, hydrolyzed sodium hyaluronate, trehalose, and water.

[0098] 2. Process

[0099] Dissolve the above ingredients in water according to the proportion, stir evenly to obtain a mixed solution, divide the mixed solution into freeze-dried bottles, vials or docking bottles, and then put it into a vacuum freeze dryer, set the pressure and freeze-dryer Drying curve, according to the setting procedure to obtain a solid powder, which is freeze-dried powder.

[0100] The freeze-dried powder formula is: 0.1 g of bone marrow mesenchymal stem cell supernatant, 15 g of trehalose, 8 g of hydrolyzed sodium hyaluronate, 50 g of palmitoyl tripeptide-1, and 26.9 g of water; the preparation process of the freeze-dried powder is as in Example 1 mentioned.

[0101] (2) So...

Embodiment 3

[0106] Embodiment 3: A kind of cosmetic suit comprising lyophilized powder and solvent

[0107] (1) Freeze-dried powder

[0108] 1. Composition

[0109] Adipose-derived mesenchymal stem cell supernatant, palmitoyl pentapeptide-4, hydrolyzed sodium hyaluronate, dextran, and water.

[0110] 2. Process

[0111] Dissolve the above ingredients in water according to the proportion, stir evenly to obtain a mixed solution, divide the mixed solution into freeze-dried bottles, vials or docking bottles, and then put it into a vacuum freeze dryer, set the pressure and freeze-dryer Drying curve, according to the setting procedure to obtain a solid powder, which is freeze-dried powder.

[0112] The formula of the freeze-dried powder is: 20 g of supernatant of adipose-derived mesenchymal stem cells, 5 g of dextran, 5 g of hydrolyzed sodium hyaluronate, 40 g of palmitoyl pentapeptide-4, and 30 g of water; the preparation process of the freeze-dried powder is as described in Example 1.

...

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Abstract

The invention belongs to the technical field of cosmetics, and particularly discloses a freeze-dried powder containing a stem cell supernate and micro-molecule polypeptide, a solvent containing a transdermal penetration enhancer and a cosmetic set containing the freeze-dried powder and the solvent. According to the prepared freeze-dried powder, the stem cell supernate and the micro-molecule polypeptide are compounded, so that the stem cell supernate and the micro-molecule polypeptide exert a synergistic effect, and the prepared freeze-dried powder has the functions of significantly delaying aging, reducing fine wrinkles, moisturizing and tendering the skin and the like; the solvent used for dissolving the freeze-dried powder specifically contains the transdermal penetration enhancer, the situation is promoted that active components of cell factors, micro-molecule polypeptide and the like in the freeze-dried powder permeate into the dermis through the transdermal penetration enhancer, and therefore the skin protection effect of the solvent is further improved. According to the freeze-dried powder, the solvent and the cosmetic set, the freeze-dried powder and the solvent are individually packaged, the quality guaranteeing period of the cosmetic set is prolonged, no preservative is added into the freeze-dried powder, and it is effectively ensured that the active components in the freeze-dried powder are not influenced.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, and in particular relates to a freeze-dried powder containing stem cell supernatant and a small molecule polypeptide, a solvent containing a transdermal penetration enhancer, and applications of the freeze-dried powder and the solvent. Background technique [0002] In recent years, bio-gene technology has made great progress, bringing new development opportunities to the beauty and cosmetics industry, and gradually developing from traditional synthetic cosmetics and natural cosmetics to bio-gene beauty products. At the same time, with the improvement of living standards and education levels, consumers' attention to cosmetics has gradually shifted from the advertised effects to the ingredients and efficacy of cosmetics, in order to ensure that beauty products can really effectively improve skin conditions. Existing biogenetic beauty products mainly use polypeptide protein, growth factor, etc. as...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/98A61K8/64A61K8/02A61K8/67A61Q19/08A61Q19/00
CPCA61K8/022A61K8/64A61K8/676A61K8/981A61K2800/592A61K2800/84A61Q19/00A61Q19/08
Inventor 张哲
Owner STEMIRNA THERAPEUTICS CO LTD
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