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Solid spray containing nano inclusion as well as preparation method and application thereof

A kind of inclusion and nanotechnology, applied in the direction of medical preparations containing active ingredients, skin care preparations, pharmaceutical formulas, etc., can solve problems that affect product stability and usability, limited addition of functional ingredients, and easy delamination

Inactive Publication Date: 2021-05-18
广州吉岚生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the stability of nanomaterials in low-viscosity skin care products is poor, and they are easy to delaminate, which affects the stability and usability of products
[0008] In the current cosmetics, there is a certain contradiction between the efficacy of the product and the feeling of use. The skin care products with better efficacy are sticky in quality, and the skin care products with refreshing texture have a limited amount of functional ingredients.

Method used

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  • Solid spray containing nano inclusion as well as preparation method and application thereof
  • Solid spray containing nano inclusion as well as preparation method and application thereof
  • Solid spray containing nano inclusion as well as preparation method and application thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0059] This embodiment provides a solid spray containing nano-inclusions, in parts by weight, the solid spray containing nano-inclusions includes 4 parts of magnesium sodium lithium silicate, PEG-240 / HDI copolymer bis-decyl deca Tetrol polyether-20 / 6 parts of butanediol, 3 parts of betaine, 7 parts of propylene glycol, 3 parts of nano-composition for acne removal and 77 parts of water.

[0060] The preparation method of the solid spray containing nano inclusions comprises the following steps:

[0061] Add sodium lithium magnesium silicate and PEG-240 / HDI copolymer bis-decyltetradeceth-20 / butylene glycol into water, stir at 82°C and 900rpm, cool to 48°C, then add Acne Removing Copolymer The nano composition, betaine and propylene glycol were transported and mixed at 900 rpm for 9 minutes to obtain the solid spray containing nano inclusions.

Embodiment 2

[0063] This embodiment provides a solid spray containing nano-inclusions, in parts by weight, the solid spray containing nano-inclusions includes 1 part of magnesium sodium lithium silicate, PEG-240 / HDI copolymer bis-decyldecyl Tet-20 / 1 part of butanediol, 1 part of betaine, 0.5 part of ceramide nano composition, 0.1 part of methylparaben and 96.4 parts of water.

[0064] The preparation method of the solid spray containing nano inclusions comprises the following steps:

[0065] Add sodium lithium magnesium silicate, PEG-240 / HDI copolymer bis-decyltetradeceth-20 / butylene glycol and methylparaben to water, stir at 80°C and 1000rpm, cool to 45°C, and then Add the ceramide nano composition and betaine, and mix at 800 rpm for 12 minutes to obtain the solid spray containing nano inclusions.

Embodiment 3

[0067] The present embodiment provides a solid spray containing nano-inclusions, in parts by weight, the solid spray containing nano-inclusions comprises 9 parts of magnesium sodium lithium silicate, 9 parts of xanthan gum, 5 parts of betaine, 10 parts of propylene glycol 5 parts of anti-aging nano lipid vesicles, 0.4 parts of methylparaben, 1 part of phenoxyethanol and 60.6 parts of water.

[0068] The preparation method of the solid spray containing nano inclusions comprises the following steps:

[0069] Add sodium lithium magnesium silicate, xanthan gum and methyl paraben into water, stir at 85°C and 800rpm, cool to 50°C, then add anti-aging co-delivery nano lipid vesicles, betaine, propylene glycol and phenoxy Ethanol, mixed at 1000 rpm for 8 minutes to obtain the solid spray containing nano inclusions.

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Abstract

The invention provides a solid spray containing a nano inclusion as well as a preparation method and application thereof. The solid spray containing the nano inclusion comprises solid water and the nano inclusion dispersed in the solid water; and the solid water comprises a thixotropic agent, a thickening agent and a humectant. The preparation method of the solid spray containing the nano inclusion comprises the step of mixing the thixotropic agent, the thickening agent, the humectant, the nano inclusion, an optional type of preservative and the water. According to the solid spray containing the nano inclusion, the nano inclusion wrapped with active ingredients is combined with the solid water, so that the stability of the active ingredients in a system and the infiltration capacity of the active ingredients to skin are improved, the residence time of the active ingredients in the skin is prolonged, the skin care effect is better, the bioavailability is better, a product does not irritate the skin, and the texture is fresh and cool; and the preparation method is scientific, efficient, simple to operate and extremely high in application value.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, and in particular relates to a solid spray containing nano inclusions and a preparation method and application thereof. Background technique [0002] In order to improve the skin care efficacy of skin care products, functional ingredients are usually added to the system to achieve corresponding maintenance effects, such as whitening agents, antiaging agents and acne removing agents. The efficacy of skin care products is closely related to the amount of functional ingredients added, but too much added amount of functional ingredients may cause the following problems: [0003] (1) Safety: Some active ingredients are irritating to a certain extent. If the amount added is too high, it may cause irritating reactions such as redness and allergies. It is not suitable for people with sensitive skin; [0004] (2) Effectiveness: Excessive addition of active ingredients will make the permeability worse, ...

Claims

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Application Information

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IPC IPC(8): A61K8/14A61K8/25A61K8/34A61K8/49A61K8/68A61K8/73A61K8/86A61Q19/00A61Q19/02A61Q19/08
CPCA61K8/14A61K8/25A61K8/347A61K8/498A61K8/68A61K8/73A61K8/86A61K2800/10A61Q19/00A61Q19/005A61Q19/02A61Q19/08
Inventor 吴培诚
Owner 广州吉岚生物科技有限公司
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