20 results about "Contagious disease" patented technology

A user score of a test for assessing a risk of a user of having or developing a contagious illness may be obtained, for each user of a plurality of users entering in a group setting. A group score based on the user scores associated with the plurality of users in the group setting may be generated. The group score indicating a group risk of a presence or development of the contagious illness in the group setting may be communicated for display. Group scores associated with a plurality of group settings may be obtained and communicated for display. A message may be communicated to a mobile user device indicating a group setting as a current high risk group setting, being associated with a score that is outside a limit set by a threshold value and with a location in proximity to a current location of the mobile user device.

The invention relates to the field of public safety, in particular to a building emergency evacuation behavior selection research method based on emotion infection. According to the method, emotional infection intensity data is obtained through a questionnaire, a hybrid selection model (HCM) considering emotional infection is constructed, and a P-SIR model combining an OCEAN model and an SIR infectious disease model is introduced to simulate the emotional infection process. Anylogic simulation software is used for carrying out a simulation experiment on path selection of evacuated people, and the influence of psychological latent variables such as emotional infection on emergency evacuation path selection is explored. According to the method, the problems that in existing research, an emotion infection model is not considered carefully, and psychological factors in a mixed selection model are not considered comprehensively are solved, the accuracy and practicability of an emergency evacuation model are improved, and theoretical support and basis are provided for an emergency management department to formulate an effective library emergency evacuation management strategy and building design specifications.

The present invention relates to a system (1) for detecting a disease in a person, in particular a contagious disease such as COVID-19, this detection system comprising: —an acquisition device (7) for acquiring examination data on the person, this acquisition device comprising, in particular, at least one physiological measurement sensor such as a radar, and a thermal camera for acquiring this examination data, —a data processing device (3) arranged to receive this examination data obtained by the acquisition device, —a display device (30) arranged to display diagnostic information on the disease based on an analysis of the examination data, this diagnostic information possibly being representative of a level of probability that the person has the disease.

The utility model provides an anti-sputtering intervertebral bone grafting device suite with a cover, and belongs to the technical field of medical instruments. Comprising a bone grafting funnel and a bone grafting rod, a handle is installed outside an expansion part, the bone grafting rod is installed in a funnel handle, a push plate is installed on the outer surface of the bone grafting rod, the expansion part is installed on the outer surface of the funnel handle, a metal cover is installed on the outer surface of the bone grafting rod, a groove is formed in the metal cover, the bone grafting rod is installed in the groove, and a positioning groove is formed in the metal cover. And the expansion part is fixed in the positioning groove. According to the bone grafting funnel, the metal cover is arranged, the bone grafting rod is installed in the groove formed in the metal cover, when the bone grafting rod is inserted into the bone grafting funnel, the metal cover can naturally slide down to cover the opening in the top end of the expansion part, the top end of the expansion part is fixed in the positioning groove, and when a hammer is used for knocking, blood splashed from the intervertebral space can be blocked by the metal cover; the blood of a patient suffering from infectious diseases is isolated, and the wound pollution risk caused by the fact that the blood splashes out of the wound and then falls back is avoided.

This invention provides an adjustable curved sheath surgical robot, comprising a carriage, an adjusting arm, and an adjustable curved sheath electric control mechanism. A moving component is located at the bottom of the carriage for moving the adjustable curved sheath surgical robot; a lifting component is located on the carriage, the output end of which is connected to the head end of the adjusting arm for driving the adjusting arm to rise and fall. The end of the adjusting arm is connected to the adjustable curved sheath electric control mechanism, and the adjusting arm has a rotation joint and a pitch joint for driving the adjustable curved sheath electric control mechanism to rotate and pitch. The adjustable curved sheath electric control mechanism is used to install and operate the adjustable curved sheath. This invention replaces traditional manual surgery with an electrically controlled adjustable curved sheath surgical robot, which can reduce the burden on doctors and reduce the risk of transmission of lung infectious diseases.

The present invention provides an aqueous solution composition capable of rapidly preventing, alleviating or eliminating symptoms of acute respiratory diseases by applying a hypertonic aqueous solution composition containing molecular iodine to all parts of the eyes, oral cavity, nasal cavity, and respiratory tract. The present invention provides a hypertonic aqueous solution composition containing molecular iodine, which can prevent and eliminate acute respiratory infectious diseases such as cold, flu, and COVID-19, and can rapidly alleviate or eliminate runny nose and nasal congestion caused by allergic and non-allergic rhinitis.

A system and method that enables users to provide authenticated medical records (e.g., vaccination records, viral anti-body test results, etc.) to a third-party (e.g., a venue) to gain access to the third-party is provided. In this way, the third party may confirm that the user is sufficiently immune to a particular disease (e.g., COVID-19) and may thereby minimize the threat of the user introducing the contagious disease to the third party. The system includes a biometric data recognition system that authenticates the identity of a user, a medical records acquisition system that acquires the medical records of the authenticated user, and a system for the displaying or otherwise providing the medical records to the third-party for review. The system also includes a system identification card that includes the user's contact information, alphanumeric characters associated with the user's driver's license number, medical records of the user, and other elements.

The disclosure relates to laminate structures to cover or protect substrates or surfaces. The laminate structure comprises a support layer and a self-sterilizing / antimicrobial layer comprising a sulfonated polymer, capable of killing microbes within minutes and for an extended period of time. The sulfonated polymer has a sufficient degree of sulfonation to kill in less than 120 minutes at least 90% of microbes in contact with the surfaces, and for extended protection of the surfaces for at least one month. The laminate structure is particularly suitable for protecting high-touch surfaces such as door knobs, touch-screens, tables, as well as for use with facemasks, face shields, or as self-sterilizing wraps for surgical instruments and supplies. The laminates can also be used as garments or to cover / protect personnel having contagious diseases, etc., to decrease the transmission of microbes.

The present invention discloses an air curtain system for supplying and exhausting air in a ward and a method of using the same, comprising air distribution boxes, room return air outlets and independent exhaust hoods which are arranged opposite to each other on both sides of a hospital bed, wherein the two air distribution boxes have the same structure, an air curtain air supply outlet is provided on the top of the air distribution box, a second air exhaust outlet is provided on the bottom of the air distribution box, a first air exhaust outlet is provided on the side of the air distribution box away from the hospital bed, a horizontal air supply outlet and an air exhaust outlet are provided on the side of the air distribution box close to the hospital bed, all the air outlets are connected through an air duct, a first opening and closing guide valve and a second opening and closing guide valve are provided on the air duct, fans are provided in the air curtain air supply outlet, the second air exhaust outlet and the air exhaust outlet; the air delivered by the air curtain air supply outlet enters the independent exhaust hood or the room return air outlet, the air supply and exhaust air curtain system of the present invention specifically purifies the air around the patient, improves the air quality in the patient's breathing zone, and avoids mutual infection between the patient and medical staff, and can be mainly applied to respiratory infectious disease wards in hospitals.

The invention discloses a method for intelligently regulating and controlling a negative pressure isolation hood based on multi-modal filtering, relates to the technical field of medical protection equipment, and solves the problems of sudden pollution response lag, filter screen failure protection interruption and poor man-machine adaptability caused by single parameter regulation and control of a traditional isolation hood. Isomerous data inside and outside the hood are synchronously collected through a multi-mode sensing unit; inputting the data into a dynamic decision model, fusing an environment safety coefficient, a filtering efficiency attenuation curve and a user comfort evaluation function, and generating an optimal negative pressure threshold in real time; the power of a stepless frequency conversion fan is adaptively adjusted, the lower limit of negative pressure is maintained to be higher than-25 Pa when the aerosol concentration suddenly increases, the fluctuation amplitude is controlled when breathing is abnormal, the service life is predicted according to the pressure difference change rate of a filter screen, and the power is compensated in advance; and parameters are controlled through a closed-loop feedback mechanism, fault diagnosis is started, and a standby strategy is switched. The method is used for prevention and control of infectious diseases, can improve the sudden pollution response speed, prolongs the service life of the filter screen, and remarkably improves the wearing comfort.

The present invention relates to a crystalline compound or a basic salt thereof, a preparation method therefor, and a use thereof. The compound is a PD-1 / PD-L1 inhibitor having a compound structure as represented by the following formula (I). The crystalline compound has moderate hygroscopicity, improved solubility, good crystallinity, and stable physicochemical properties, and the basic salt of the crystalline compound has good crystallinity, good solubility, and stable physicochemical properties, meets industrial production requirements, and satisfies the need for the development of clinical pharmaceutical formulations. The crystalline compound or the basic salt thereof in the present invention can be widely applied to the preparation of drugs for treating PD-1 / PD-L1 signaling pathway-mediated tumors, immune-related diseases and disorders, contagious diseases, infectious diseases, or metabolic diseases.

Provided are compounds and methods of treating diseases caused by a Coronaviridae virus such as SARS-CoV-2, SARS-CoV, and MERS-CoV coronaviruses by administering nitrogen-containing heterocyclic compounds. SARS (Severe Acute Respiratory Syndrome), MERS (Middle East Respiratory Syndrome), and, particularly, COVID-19 are highly contagious diseases with high mortality rate responsible for tens of millions of infections and almost two million deaths around the globe.

The invention relates to a lower limb X-ray radiography squeezer which is characterized in that the periphery of a single chip microcomputer is connected with a host wireless communication module (12), an outlet of an inflator pump (6) is connected with a gas storage bottle (7), and a remote controller wireless communication module (14) arranged in a wireless remote controller and the host wireless communication module jointly form wireless communication; an RFID read-write module is arranged on the host control circuit board and communicates with a radio frequency electronic tag (11) embedded in a disposable extrusion strap (10), and the unique ID of the radio frequency electronic tag embedded in the disposable extrusion strap, the number of use times set in the radio frequency electronic tag and the use time are subjected to identification and read-write monitoring through a single-chip microcomputer. The method has the advantages that the risk that a patient is injured by explosion of a disposable extrusion strap air bag due to illegal use of counterfeit, non-original and inferior extrusion straps, repeated over-time fatigue use, overtime fatigue use and the like is avoided, and the risk that infectious diseases are spread due to repeated use of multiple persons is avoided.

A method of assistance in controlling the spread of a contagious disease, using networked devices, is disclosed. The method includes upon receiving data relating to infection by the disease of a first user of a first mobile terminal, obtaining a list including data of successive geographical positions of the first terminal over a predetermined period of time, and estimating a region at risk of infection by the first user, and for a second terminal available to a second user: obtaining a geographical position datum of the second terminal during the period of time, and comparing the geographical position of the second terminal to the region at risk by the datum of the second terminal, in the event of a coincidence between the geographical position of the second terminal and the region at risk, activating a human-machine interface connected to the second terminal to inform the second user of a risk.

An auscultation device that can be used for telemedicine consultations and real-time telemedicine monitoring. The digital stethoscope includes a detector of analog acoustic signals from the patient and a data processing system implemented via a secure encrypted web-protocol and accessible via the user interface of a progressive web-application on a portable computing device of the patient / physician with connected headphones. The acoustic signal detection device comprises a sequentially connected audio microphone, an analog signal pre-amplifier, an ADC, a microcontroller, and a battery. The microcontroller combines the signals from the ADC and the device status signals into a single packet and transmits it wirelessly to the data processing system. The software processing is carried out on the physician's or patient's device. An increase in the quality / speed of signal processing is achieved with reduced power consumption and with the possibility of safe auscultation of patients with highly contagious diseases, e.g., COVID-19.

The present invention relates to compounds of formula (I) that are capable of modulating, e.g., inhibiting or activating, one or more kinases, especially LRRK2 and / or NUAK1 and / or TYK2 or mutants thereof. The compounds are useful for treating diseases, such as autoimmune diseases, inflammatory diseases, bone diseases, metabolic diseases, neurological and neurodegenerative diseases, cancer, cardiovascular diseases, allergies, asthma, Alzheimer's disease, Parkinson's disease, skin disorders, eye diseases, infectious diseases and hormone-related diseases. The present description discloses the synthesis and characterisation of exemplary compounds as well as pharmacological data thereof (e.g. pages 40 to 146; examples 1 to 63; compounds 1 to 248; tables 1 to 3). Preferred compounds are e.g. 1,4-dihydrobenzo[d]pyrazolo[3,4-f][1,3]diazepine derivatives and related compounds. An exemplary compound is e.g. 5-(2,6-difluorophenyl)-8-methoxy-1,4-dihydrobenzo[d]pyrazolo[3,4-f][1,3]diazepine (example 49). (Formula (II):

A method for visualizing and supporting a contextual diagnostic decision for contagious diseases is provided. The method includes receiving, from a diagnostic instrument, information regarding a sample cartridge, including a location data and a risk factor, the sample cartridge including multiple test assays for diagnosing multiple infectious diseases. The method also includes selecting a test assay for reporting a diagnostic result, instructing the diagnostic instrument to run the test assay from the sample cartridge, receiving, from the diagnostic instrument, a first data set when the test assay is completed, and assessing a diagnostic result based on the first data set. A system and a non-transitory, computer-readable medium storing instructions to cause the system to perform the above method are also provided.

A method for mitigating the spread of infectious diseases among dialysis patients is provided. The method comprises: receiving, by a prediction system and from a medical facility, individual treatment data indicating dialysis treatment information associated with a patient undergoing dialysis treatment; receiving, by the prediction system and from a blood testing laboratory, individual lab data indicating blood analysis information associated with the patient; determining, by the prediction system, disease analysis results for the patient based on inputting the individual treatment data and the individual lab data into a disease prediction machine learning (ML) model, wherein the disease analysis results indicate a likelihood of the patient being infected with a contagious disease; and providing, by the prediction system and to the medical facility, instructions indicating one or more responsive actions based on the disease analysis results.

The present invention relates to compounds of formula (I) that are capable of modulating, e.g., inhibiting or activating, one or more kinases, especially LRRK2 and / or NUAK1 and / or TYK2 or mutants thereof. The compounds are useful for treating diseases, such as autoimmune diseases, inflammatory diseases, bone diseases, metabolic diseases, neurological and neurodegenerative diseases, cancer, cardiovascular diseases, allergies, asthma, Alzheimer's disease, Parkinson's disease, skin disorders, eye diseases, infectious diseases and hormone-related diseases. The present description discloses the synthesis and characterisation of exemplary compounds as well as pharmacological data thereof (e.g. pages 40 to 146; examples 1 to 63; compounds 1 to 248; tables 1 to 3). Preferred compounds are e.g. 1,4-dihydrobenzo[d]pyrazolo[3,4-f][1,3]diazepine derivatives and related compounds. An exemplary compound is e.g. 5-(2,6-difluorophenyl)-8-methoxy-1,4-dihydrobenzo[d]pyrazolo[3,4-f][1,3]diazepine (example 49). (Formula (II):