39results about How to "Accurate curative effect" patented technology

The invention discloses a methylated marker IL-2RG in a systemic lupus erythematosus (SLE) whole blood genome and application thereof. The sequence of the marker is shown as SEQ ID NO:1. The methylated marker IL-2RG in the SLE whole blood genome is applied to the preparation of a reagent for diagnosing SLE, in particular to a kit for diagnosing SLE. By detecting the methylation level of the methylated marker IL-2RG, a specific methylation locus with a great meaning and a remarkable difference is counted and taken as a basis for early diagnosis of SLE. By adopting the methylated marker, an accurate, cheap and quick clinical tool for early diagnosis of SLE, the disease activity, the curative effect and the prognostic evaluation is provided.

The invention discloses a traditional Chinese medicine composition for treating gout. The traditional Chinese medicine composition for treating gout is prepared from the following raw materials in parts by weight: 8-12 parts of salvia miltiorrhiza, 6.75-12 parts of polygonum cuspidatum, 6.75-9 parts of radices sileris, 6.75-12 parts of gentiana macrophylla, 9-12 parts of scutellaria baicalensis, 4.5-8 parts of rhizoma corydalis, 4.5-8 parts of cassia twig and 6.75-12 parts of medlar. The traditional Chinese medicine composition for treating gout, which is provided by the invention, has remarkable anti-inflammatory and abirritation effects, is capable of remarkably lowering the content of blood uric acid, good in treatment effect on gout, short in treatment period, low in cost, and free from obvious toxic and side effects and adverse reactions, and provides a new choice for clinic.

The invention relates to the technical field of medicinal preparations, and in particular discloses a multimodal contrast agent and use thereof. The multimodal contrast agent is composite nanoparticles of mesoporous silica-supported copper sulfide and perfluorohexane; the cores of the composite nanoparticles are made from copper sulfide, and mesoporous silica is used as a shell for wrapping the copper sulfide; pores of the mesoporous silica are filled with the perfluorohexane, and the outer surface of the mesoporous silica is connected with polyethylene glycol. The multimodal contrast agent isapplied to an ultrasound imaging reagent, a photoacoustic imaging reagent, cavitation treatment and a photothermotherapy reagent. The multimodal contrast agent provided by the invention is low in cytotoxicity, good in biocompatibility, has the functions of bimodal imaging / photothermal therapy and cavitation treatment, realizes multi-mechanism treatment of tumor homologues, and improves the curative effect; furthermore, the multimodal contrast agent is simple in preparation process and low in cost.

The present invention relates to Chinese medicine preparation, and is especially one kind of Tongshu oral cavity refreshing tablet and its preparation process. The tablet with the functions of clearing away heat, eliminating wetness, eliminating turbidity and relaxing the bowels is prepared with rhubarb, immature bitter orange, capillary artemisia, tree peony bark, angelica and other Chinese medicinal materials.

The invention provides a Chinese medicinal formulation for treating enuresis and urinary incontinence, which is prepared from Chinese medicinal herbs including keel, raspberry, bitter cardamon, rhizoma dioscoreae, leek seeds, gen-seng, astragalus root, licorice root, cherokee rose, grassleaved sweetflag rhizome, chicken's gizzard-skin, and wild jujuba seeds.

The invention provides a kit for estimating coronary artery diseases. The kit comprises a detection reagent for detecting concentrations of Cer(d18:1 / 16:0), Cer(d18:1 / 18:0), Cer(d18:1 / 24:0) and Cer(d18:1 / 24) in a sample of a study subject and a specification. The kit can be efficiently and accurately used for the diagnosis, risk stratification, illness monitoring and curative effect evaluation ofthe coronary artery diseases, is good in sensitivity and specificity and can meet the clinical diagnosis and treatment requirement of the coronary artery diseases.

The invention relates to a tooth movement evaluation method under a curve natural coordinate system based on an alveolar bone form and belongs to the technical field of dental orthodontics. An alveolar arch curve is constructed based on the alveolar bone form, the curve natural coordinate system is constructed based on the alveolar arch curve and the alveolar bone form, and then, the coordinates, the amount of movement, and the direction of movement of a tooth are calculated on the basis of the curve natural coordinate system. The invention provides the evaluation method of the movement of the tooth relative to the alveolar bone and having a physiological significance, and the evaluation method is beneficial to more scientific, more reasonable and more accurate tooth movement scheme design and curative effect evaluation.

The present invention relates to a Chinese medicine toxin-expelling face-nourishing tablet and its preparation method. It is made up by using the Chinese medicinal materials of rhubarb, bighead atractylodes rhizome, American ginseng, mirabilite, unripe bitter orange, cynanchum otophyllum, rubia yunnanensis, cistanche stem and lotus leaf.

The invention relates to a thrombus removal device of a thrombus removal system. The thrombus removal device is used in cooperation with the thrombus removal system and is suitable for removing thrombi, thrombus debris, blood clots, blood lipid plaques, atherosclerosis matter and other foreign bodies in the blood vessels and removing blood vessel thrombi formed on the inner surfaces of blood vessel stents placed in the blood vessels and caused hyperplasia of the blood vessel endothelia. The thrombus removal device of the thrombus removal system comprises a puncture head, a guide wire, a frontcatheter, a middle catheter, a front cannula, a front balloon, a front balloon liquid catheter, a front support sleeve, a front collection basket, a front thrombectomy device, a front catheter and middle catheter telescopic connection mechanism, a middle catheter and rear catheter telescopic connection tube, a rear catheter, a rear catheter cannula, a rear balloon, a rear balloon liquid catheter,a rear support sleeve, a rear collection basket, a rear thrombectomy device and a negative-pressure suction tube; the middle catheter at the rear portion of the front collection basket is provided with the front thrombectomy device; the rear catheter at the front portion of the rear collection basket is provided with the rear thrombectomy device.

The invention relates to a sugar-reducing comfort pill and a preparation method thereof. The sugar-reducing comfort pill is prepared from traditional Chinese medicine raw materials such as ginseng, barbary wolfberry fruit, membranous milkvetch root, manyprickle acanto-panax root, sealwort, sharpleaf galangal fruit, oyster shell, rehmannia root, radix rehmanniae preparata, kudzuvine root, radix salviae miltiorrhizae, lychee seed, common anemarrhena rhizome, gypsum, gordon euryale seed, common yam rhizome, figwort root, Chinese magnoliavine fruit, dwarf lilyturf tuber, combined spicebush root, mongolian snakegourd root, bitter orange and the like.

The invention discloses a low-frequency therapeutic apparatus for drug detoxification, which is regulated and controlled by a computer and is equipment for the drug detoxification and solves the problem of poor effects of healing with drugs for the drug detoxification in the past. The low-frequency therapeutic apparatus for the drug detoxification, regulated and controlled by the computer, comprises a power source and a shell, the shell is internally provided with a controller and the input end of the controller is connected with the computer while the output end of the controller is connected with a therapeutic electrode. By virtue a method of acupuncture points and meridians in the traditional Chinese medical science, a pulse signal generated by the driving of the controller by the computer passes through the therapeutic electrode and a skin electric shocking pulse is directly adopted to stimulate acupuncture points of a human body for treatment, thus promoting the releasing of enkephalin in the human body, further relieving the withdrawal symptoms of opiate narcotics and having the effects of pain easing and spasmolysis and better withdrawal effect than amidone methadone. The therapeutic apparatus of the invention has safe and reliable application, no pain, no side effect, and obvious effects for relieving addiction and controlling relapse. The computer is used for regulating and controlling so as to realize simple operation and accurate curative effect.

A compound isopropylphenol injection containing local anesthetic contains proportionally isopropylphenol, the local anesthetic chosen from procaine, lidocaine, etc, the refined plant oil for injection, emulsifier, isotonic regulator, antioxidant, pH regulator and the water for injection. Its preparing process is also disclosed.

The invention relates to a traditional Chinese medicine compound preparation, and discloses an immunity-enhancing capsule. The capsule is prepared from the following components in parts by weight: 230-260 parts of grape skin extract, 15-30 parts of vitamin C, 50-70 parts of magnesium stearate and 50-70 parts of mannitol. The immunity enhancing capsule has the advantages of good immunity regulating effect, no toxic or side effect and high safety. Resveratrol which is contained in grape skin and is richer than that in grape pulp and grape seeds is a polyhydroxyphenol compound, is capable of preventing cardiovascular and cerebrovascular diseases, and has an extremely strong cancer resistance. The invention further discloses a method for preparing the immunity-enhancing capsule. The preparation method is easy to operate, is environmentally friendly, economic, effective and non-toxic, and has a wide application prospect.

The invention belongs to the technical field of agriculture planting and discloses a planting method capable of reducing content of cyanophoric glycosides in cherry fruits. The method comprises steps as follows: (1) forest land control; (2) forest land clearing; (3) density control; (4) preparation of afforestation land; (5) application of base fertilizer and backfilling of surface soil: 10-20 kg of compost is applied to each hole while backfilling of the surface soil is performed, and 5-10 kg of a mannitol solution is sprayed to each hole; (6) selection of seedlings; (7) planting; (8) cultivation management. The planting method capable of reducing the content of cyanophoric glycosides in the cherry fruits is provided, the content of cyanophoric glycosides in the cherry fruits is reduced, and the economic benefits of planting are improved.

The present invention relates to Chinese medicine mixture preparation, and is especially the preparation process of Puerariae Decoction mixture. The preparation process includes the steps of leaching, separating, purifying, and concentrating. The preparation process features its effective Chinese medicine component separating step, which is ultrafiltering separation adopting organic membrane or inorganic ceramic membrane of molecular weight 10-50 KDa; and its concentrating step, which includes nanofiltering purification and concentration with organic membrane of molecular weight 150-200 Da. Thus prepared Puerariae Decoction mixture is clear, transparent, reddish brown and accurate in effective components, and has unique smell, high storage stability and accurate curative effect.

The invention discloses a medicine and embolism particle mixed injection device capable of being remotely controlled. The medicine and embolism particle mixed injection device comprises a console andan execution structure, wherein the execution structure comprises a first injector, a second injector, an injector fixing device, an injector pushing device, an injector stroke limiting device, a controller II and a serial port display screen; the console comprises a controller I; and the controller I is connected with the controller II, a touch display screen, a power-on button, a safety mechanism button, a real-time speed control rocker, a maximum pressure control knob, a maximum speed control knob, an analog signal collector and a heat dissipation module. The medicine and embolism particlemixed injection device is simple and reliable to operate, and can realize remote non-contact sterile medicine and embolism material mixed injection operation, vibrator mixing of medicines and granularembolism materials, accurate injection speed and dosage control and real-time monitoring of injection flow and pressure, so that the accurate embolism curative effect is achieved, the exposure time for interventional physicians to inject the medicines in an operation is greatly shortened, and the work intensity of the physicians is reduced.

The invention relates to a thrombus removing system which is suitable for removal of foreign matters such as thrombi, thrombus fragments, blood clots, blood lipid plaques and atherosclerotic substances in blood vessels and is also suitable for removing blood vessel thrombi formed on the inner surfaces of blood vessel stents placed in blood vessels of a human body and causing vascular endothelial hyperplasia. The thrombus removing system comprises a thrombus removal device and an operating handle portion, wherein the thrombus removal device is connected with the operation handle portion througha rear catheter; the thrombus removal device comprises a puncture head, a guide wire, a front catheter, a middle catheter, a front cannula, a front balloon, a front balloon catheter, a front supportsleeve, a front collection basket, a front thrombectomy device, a front catheter and middle catheter telescopic connection mechanism, a middle catheter and rear catheter telescopic connection tube, arear catheter, a rear catheter cannula, a rear balloon, a rear balloon catheter, a rear support sleeve, a rear collection basket, a rear thrombectomy device and a negative-pressure suction tube; the front thrombectomy device is arranged on the middle catheter at the rear portion of the front collecting basket; the rear thrombectomy device is disposed on the rear catheter in front of the rear collection basket.

The invention is concerned with a kind of Chinese traditional medicine to cure vitiligo. It relates to 10 to 20 shares of arnebia or lithosperm root, 10 to 20 shares of dalbergia wood, 10 to 20 shares of Yunnan Manyleaf paris Rhizome, 10 to 20 shares of head stephania root, 10 to 20 shares of ampelopsis root, 10 to 20 shares of peach kernel, 10 to 20 shares of safflower, 5 to 10 shares of atractylodes rhizome, 5 to 10 shares of chinese gentian, 70 to 80 shares of cuttle bone, 10 to 15 shares of liquorice, 200 to 250 shares of leucopuncturevine, 200 to 250 shares of psoralea fruit, 90 to 110 shares of dahurian angelica and 10 to 20 shares of zaocys dhumnades in weight percent. This medicine has 10 to 15 shares of cassia, 10 to 15 shares of cassia twig, 10 to 15 shares of prepared liquorice, 20 to 30 shares of rhizome of king solomonseal and 20 to 30 shares of asiabell in weight percent. This medicine has exact curative effect, high efficiency, small side effection and low cost to be preparaed and took by self, and it can be prepared through industrialization and can be popularized for using.

The invention provides a kit for evaluating coronary artery diseases. The kit comprises a detection reagent and a specification, wherein the detection reagent is used for detecting the concentrations of Cer (d18:1 / 16:0), Cer (d18:1 / 18:0), Cer (d18:1 / 24:0) and Cer (d18:1 / 24:1) in a sample of a tested object. The kit disclosed by the invention can be efficiently and accurately used for coronary artery disease diagnosis, risk stratification, illness state monitoring and curative effect evaluation, is relatively good in sensitivity and specificity, and can meet the requirements of clinical diagnosis and treatment of coronary artery diseases.

The invention relates to an establishment method of a coordinate system based on a target dental arch curve, and an automatic tooth arrangement method and a tooth movement evaluation method established based on the coordinate system of the dental arch curve. The dental arch curve coordinate system has different local coordinate systems consisting of a tangent axis, a main normal axis and a secondary normal axis at different points of a curve, and adapts to three-dimensional positions of teeth, so that more efficient and accurate automatic tooth arrangement can be guided, and clinical tooth movement evaluation can be better met; more scientific, more reasonable and more accurate tooth movement scheme design and curative effect evaluation are facilitated.

The invention provides a primer group and a kit for detecting mRNA (messenger Ribonucleic Acid) expression of cationic protein of human eosinophilic granulocyte, and relates to the technical field of biological detection. The primer group disclosed by the invention comprises an ECP-F, an ECP-R, a GAPDH-F and a GAPDH-R; the nucleotide sequence of the ECP-F is as shown in SEQ ID NO. 1; the nucleotide sequence of the ECP-R is as shown in SEQ ID NO. 2; the nucleotide sequence of the GAPDH-F is as shown in SEQ ID NO. 3; and the nucleotide sequence of the GAPDH-R is as shown in SEQ ID NO. 4. The invention further provides a kit comprising the above primer group, the expression level of human ECP mRNA can be quantitatively detected by a one-step method, and a detection means with high accuracy, wide detection range and high sensitivity is provided for detection of the protein.

The invention relates to a primer probe group and a kit for human leukotriene receptor CysLTR2 mRNA RT-PCR (reverse transcription-polymerase chain reaction) detection, and belongs to the technical field of biological detection. The primer probe group comprises a primer CysLTR2-F, a primer CysLTR2-R and a probe C2-Probe, the nucleotide sequence of the primer CysLTR2-F is shown as SEQ ID NO.1, the nucleotide sequence of the primer CysLTR2-R is shown as SEQ ID NO.2, and the nucleotide sequence of the probe C2-Probe is shown as SEQ ID NO.3. The TaqMan real-time fluorescent quantitative one-step RT-PCR detection primer probe set is established for human CysLTR2, and detection means with high accuracy, wide detection range and high sensitivity is provided for detection of the protein.

The invention discloses a quantized traditional Chinese medicine capable of treating hypertension. The quantized traditional Chinese medicine capable of treating hypertension is prepared by adopting traditional Chinese medicine decoction pieces; and the traditional Chinese medicine decoction pieces are proportioned in the following parts by weight of: 20-60 parts of cassia seeds, 5-30 parts of gambir plant nods, 5-30 parts of of chrysanthemum flowers and / or red-rooted salvia roots, and 5-30 parts of apocynum venetum leaves. Being placed in a localized directional quantum field and subjected torepeated directional quantum effects, the combined traditional Chinese medicine decoction pieces can be prepared into a quantized traditional Chinese medicine; and then, the quantized traditional Chinese medicine is subjected to a routine extraction method so as to be prepared into extract powder. Then, the extract powder is prepared into tablets, granules or capsules and aqueous agents. A pioneering quantization process is adopted so as to perform directional quantum treatment on the traditional Chinese medicine decoction pieces used in compatibility; so that, pharmacological active molecules of the traditional Chinese medicine decoction pieces with similar structure to quantum matrix in the plural pharmacologic active molecules in the traditional Chinese medicine decoction pieces used in peculiar compatibility are excited after quantum effects are generated with a quantum base material through quantum effect channels, thereby enhancing new and different targeting functions so as tomake hypertension treatment effects more accurate.

A compound isopropylphenol injection containing local anesthetic contains proportionally isopropylphenol, the local anesthetic chosen from procaine, lidocaine, etc, the refined plant oil for injection, emulsifier, isotonic regulator, antioxidant, pH regulator and the water for injection. Its preparing process is also disclosed.

The present invention relates to the field of traditional Chinese medicine composition, in particular, relates to a traditional Chinese medicine composition for effectively treating acne and a preparation method thereof, comprising the following raw materials in parts by weight: Smilax smilax, dandelion, forsythia, loquat leaf, mulberry leaves, honeysuckle, black beans, rehmannia glutinosa, and the present invention also relates to a preparation method of a traditional Chinese medicine composition for treating acne. The present invention summarizes the pathogenesis of damp heat, phlegm stagnation, and kidney deficiency on the basis of traditional wind-heat, lung-heat, and blood-heat pathogenesis theories. , blood stasis and other points of view, not only treat the symptoms but also cure the root cause, which can effectively prevent the recurrence of the disease. Smilax tuckahoe, dandelion, and forsythia in the Chinese medicine combination of the present invention can play the effect of relieving muscle surface and clearing sore toxin and introducing medicine to skin, and loquat leaf, mulberry leaf and honeysuckle mainly play the functions of dispelling wind, clearing lung heat and promoting body fluid The role of black beans and Rehmannia glutinosa mainly play the role of diuresis and dehumidification, and it has been clinically proven to have a therapeutic effect on acne.

The ingredients of a skin-repairing ointment include the following medicinal materials by weight: 50-60 parts of angelica root, 30-35 parts of myrrh, 10-12 parts of blood root, 20-25 parts of bezoar, 15-20 parts of saffron, 10-15 parts of coptis, 15-20 parts of angelica root, Rehmannia 80-100, paeonol 20-25, licorice 15-20, musk 6-8, borneol 8-10, white wax 80-85, sesame oil 1000-1200. The preparation method is to soak eight medicinal materials including angelica, myrrh, saffron, coptis, angelica, rehmannia root, paeonol bark and licorice in sesame oil and then heat and refine until slightly withered and yellow; filter and remove the residue, add borneol, dried blood and bezoar, heat and mix well before adding Insect white wax is evenly blended; cool and add musk, mix well, and let it stand to make it. It can effectively treat bedsores, diabetic wet necrosis, old non-healing wounds, carbuncles, acne, bruises, sprains, burns and non-healing infections or non-healing aseptic infections after major Western medicine surgeries.

The invention provides a traditional Chinese medicine composition for treating cancer. The traditional Chinese medicine composition takes astragalus membranaceus, angelica sinensis, codonopsis pilosula, atractylodes macrocephala, poria cocos and liquorice as sovereign drugs, and the sovereign drugs are compatible with one another, benefit qi and blood, remove blood stasis, and achieve the efficacy that pathogenic qi cannot invade the body if antipathogenic qi remains strong; the traditional Chinese medicine composition takes scorpio, scolopendra subspinipes, arisaema heterophyllum and unprocessed rhizoma pinelliae as ministerial drugs, the scorpio and scolopendra subspinipes have the efficacies of checking tetany, eliminating toxic material, removing stasis and relieving pain; the arisaema heterophyllum and unprocessed rhizoma pinelliae are used for eliminating phlegm-damp stagnation; the traditional Chinese medicine composition takes nidus vespae, turtle shell, tortoise shell, radixaconite, radix aconiti agrestis, haematitum and dioscoreaceae as adjuvant drugs, and the haematitum and nidus vespae are used for calming the adverse-rising energy and calming the middle; the turtle shell and tortoise shell are used for removing mass in the abdomen and dissipating tumor; the traditional Chinese medicine composition takes citrus reticulata blanco, fritillaria thunbergii, common burreed rhizome, curcuma zedoaria and manis pentadactyla as conductant drugs, and the citrus reticulata blanco, common burreed rhizome, curcuma zedoaria and fritillaria thunbergii are used for dispersingthe liver and rectifying qi; the manis pentadactyla directly goes to focuses, and the efficacy is timely and accurate; the drugs are compatible, have the efficacies of calming viscus, invigorating qiand promoting blood circulation, tonifying qi and strengthening exterior, counteracting toxic substances and removing stasis, activating meridians to stop pain and removing blood stasis and stagnation, and effectively prevent and treat esophagus cancer, stomach cancer, gastric cancer, intestinal cancer and cervical cancer.

The invention relates to the technical field of pharmaceutical preparations, and specifically discloses a multimodal contrast agent and its application. The multimodal contrast agent is a composite nanoparticle of copper sulfide supported on mesoporous silica and perfluorohexane. The core of the nanoparticles is copper sulfide, the mesoporous silica is used as a shell to wrap the copper sulfide, the pores of the mesoporous silica are loaded with perfluorohexane, and the outer surface of the mesoporous silica is connected with polyethylene glycol. The multimodal contrast agent is applied to ultrasonic imaging reagents, photoacoustic imaging reagents, cavitation therapy and photothermal therapy reagents. The multimodal contrast agent in the present invention has low cytotoxicity and good biocompatibility, and has the functions of dual-modal imaging / photothermal therapy and cavitation therapy, realizes multi-mechanism treatment of the same site of tumor, and improves the therapeutic effect. At the same time, the preparation process of the multimodal contrast agent in the present invention is simple and low in cost.

The invention relates to the field of traditional Chinese medicine compositions and specifically relates to a traditional Chinese medicine composition for effectively treating acne and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition comprises the following crude drugs in parts by weight: rhizoma smilacis glabrae, dandelion, fructusforsythiae, loquat leaves, folium mori, honeysuckles, black beans and radix rehmanniae preparata. The invention further relates to a preparation method of the traditional Chinese medicine compositionfor treating acne. The viewpoints such as hot and humid condition, phlegm, kidney deficiency and blood stasis are summarized on the traditional oretical basis of wind heat, lung heat and blood heat morbidity, and the traditional Chinese medicine composition is capable of treating both symptoms and root causes so as to be capable of effectively preventing repetition of diseases. The rhizoma smilacis glabrae, the dandelion and the fructus forsythiae in the traditional Chinese medicine composition disclosed by the invention can take effects of relieving surfaces of muscles, clearing acne toxinsand introducing a drug to skins, the loquat leaves, the folium mori and the honeysuckles mainly take effects of dispelling wind, clearing away the lung heat and promoting the secretion of saliva or body fluid, the black beans and the radix rehmanniae preparata mainly take effects of using diuretic of hydragogue to alleviate water retention and dehumidifying, and proven by clinical verification, the traditional Chinese medicine composition has an effect on treating acne.