Human-body absorbable trauma dressing containing Yunnan white drug powder or Yunnan white drug powder extractive

An extract and Baiyao technology, applied in the field of wound dressings containing Yunnan Baiyao, can solve the problems of not showing biological activity, reducing scars, not promoting curative effects, etc., to expand the use methods and applicable diseases, promote skin repair, and expand product categories Effect

Inactive Publication Date: 2010-08-18
王艳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The material and structure of the drug core do not show any biological activity, and cannot promote curative effect, reduce scars, etc.

Method used

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  • Human-body absorbable trauma dressing containing Yunnan white drug powder or Yunnan white drug powder extractive
  • Human-body absorbable trauma dressing containing Yunnan white drug powder or Yunnan white drug powder extractive
  • Human-body absorbable trauma dressing containing Yunnan white drug powder or Yunnan white drug powder extractive

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Raw materials: Yunnan Baiyao powder, tranexamic acid, chitosan, collagen, glycerin, polyvinyl alcohol, transforming growth factor

[0038] Methods: (1). Add 5g of glycerin, 0.05g of transforming growth factor and 3g of tranexamic acid in 100ml of water, and fully dissolve at room temperature;

[0039] (2). Add 5 g of Yunnan Baiyao powder to the solution obtained in (1), stir well and disperse by ultrasonic for 30 minutes;

[0040] (3). Take another 100ml of water, add 5g of Yunnan Baiyao powder, 7g of polyvinyl alcohol, and 3g of collagen, and fully dissolve at 70°C;

[0041] (4). Mix the solution obtained in (2) (3) (4) at 40°C, stir evenly, put it in the container and cool it rapidly to -20°C;

[0042] (5). Put the product obtained in (5) into a freeze dryer at -80°C, dry for 48 hours, and then take out the divided package.

[0043] Effects: (1). As shown in Figure 1, the product is porous and sponge-like, with a uniform and delicate appearance. Through the microst...

Embodiment 2

[0046] Raw materials: Yunnan Baiyao powder, chitosan, hyaluronic acid, mugwort leaf extract,

[0047] Methods: (1). Add 2.5g of water-soluble chitosan to 100ml of water and fully dissolve at room temperature;

[0048] (2). At the same time, take 100ml of pure water, add 2g of hyaluronic acid, 4g of Yunnan Baiyao powder, and 3g of mugwort leaf extract;

[0049] (3). Mix the solutions obtained in (1) and (2) and stir, filter out free water, fill the gel substance into a syringe, and obtain a drug-loaded hydrogel dressing after irradiation disinfection.

[0050] Effects: (1). As shown in Figure 2, the product is a viscous colloid with certain fluidity and can be used with a syringe. When used, it needs to inject or coat the wound, and then suture or bandage.

[0051] (2). The product forms a hydrogel through the cross-linked network of chitosan and hyaluronic acid, which itself has antibacterial and skin growth-promoting effects. After carrying the drug, the drug is released f...

Embodiment 3

[0053] Raw materials: Yunnan Baiyao powder, ethyl acetate, collagen, carbodiimide, glycerin

[0054] Methods: (1). Add 40g of Yunnan Baiyao powder to 100ml of ethyl acetate, reflux at 40°C for 10 hours, add 60ml of water to the solution obtained by filtration, and distill and recover ethyl acetate to obtain Yunnan Baiyao extract;

[0055] (2). Take 50ml of pure water, add 2g of collagen, 10ml of Yunnan Baiyao extract; at the same time take another 5ml of water, add 0.02g of carbodiimide;

[0056] (3). Mix the two solutions obtained in (2) and stir, filter out free water, fill the gel substance into a syringe, and obtain a drug-loaded hydrogel dressing after irradiation disinfection.

[0057] Effects: (1). As shown in Figure 3, the product is jelly-like. When used, it needs to be injected into the wound, and then sutured or bandaged.

[0058] (2). Collagen itself is an important part of human tissue, and the hydrogel structure is more compatible, which is conducive to skin re...

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Abstract

The invention discloses a human-body absorbable trauma dressing containing Yunnan white drug powder or Yunnan white drug powder extractive, which is a novel medicine-carried dressing or a novel formulation of Yunnan white drug powder. The invention has the following remarkable characteristics: (1) the dressing can be absorbed by human bodies to lessen the pain added by dressing change and reduce the treatment cost; (2) the dressing can be made into a film solid dressing or an aquagel dressing so as to expand the use modes, the scope of applications and the drug effect of the Yunnan white drug powder; and (3) the curative effect of the dressing is enhanced by selecting a carrier material, auxiliary medicaments and functional accessories and adjusting the microstructure structure. The novel absorbable Yunnan white drug powder dressing overcomes the defects of the traditional Yunnan white drug powder in use and has economic and social values.

Description

technical field [0001] The invention relates to a wound dressing, in particular to a wound dressing containing Yunnan Baiyao. Background technique [0002] Yunnan Baiyao is a world-renowned Chinese patent medicine. It is made of precious medicinal materials. It has the effects of removing blood stasis and stopping bleeding, promoting blood circulation and relieving pain, and detoxifying and reducing swelling. Successfully created in 1902, Yunnan Baiyao has been hailed as a "Chinese treasure, a holy medicine for traumatology" for its unique and miraculous effects, and has become famous all over the world and abroad for its unique and magical effects. With the continuous deepening of research on Yunnan Baiyao by medical research institutions at home and abroad, the pharmacological effects of Yunnan Baiyao have been discovered, and its efficacy has also been scientifically confirmed. It has been widely used in internal medicine, surgery, gynecology, pediatrics, ENT, and dermato...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/22A61L15/44A61L15/64
Inventor 王艳
Owner 王艳
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