Anti-microbial healing-promoting hydrogel dressing and preparation method therefor

Abstract

The invention discloses an anti-microbial healing-promoting hydrogel dressing and a preparation method therefor. The main ingredients of the dressing are water-soluble high-molecular polymers, functional polymers with pseudoplastic, anti-microbial agents and water. The above ingredients are dissolved into a whole after a series of technologies. The solution is poured into a mold, and the hydrogel dressing is obtained after curing and irradiation disinfection. The results of wound healing experiments and in vitro anti-microbial experiments show that the hydrogel dressing can promote wound healing effectively, and has good bacteriostatic activity to multiple bacteria (the sterilizing rate is above 70%). The anti-microbial healing-promoting hydrogel dressing is better than existing hydrogel dressings obviously, and has advantages of substantial anti-microbial curative effects, transparency, high water content, simple preparation method, pure product, nontoxicity, innocuousness, no stimulation, good biocompatibility and the like. The hydrogel dressing is suitable for large-area promotion and application.

Description

technical field [0001] The invention belongs to the field of medical wound dressings and preparation thereof, in particular to an antibacterial and healing-promoting hydrogel dressing suitable for the protection and treatment of burns, mechanical wounds, surgical incisions and chronic wounds and a preparation method thereof. Background technique [0002] The skin is the largest organ of the human body, and it is a natural barrier to maintain the stability of the internal environment and prevent the invasion of microorganisms; however, the large area exposed to the outside world makes the skin vulnerable to external injuries such as burns and mechanical injuries. Because Staphylococcus aureus, Escherichia coli and other pathogens multiply on the wound, it is easy to cause wound infection; the infected wound is not easy to heal, and it is easy to cause loss of body fluid and various complications. [0003] Gauze-type dressings, known as traditional dressings, are generally mad...

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