23 results about "Diabetic care" patented technology

The invention belongs to the technical field of food processing, and particularly relates to a product with peony peptide and ginseng peptide as main raw materials and a preparation method of the product. According to the invention, leftovers such as ginseng root hair and peony seed meal are used as raw materials, so that the production cost is greatly reduced, and the prepared product is presented in the form of a solid beverage and is convenient to carry and drink; the ginseng peptide is prepared by adopting a steam explosion and biological enzymolysis technology, the peony peptide is prepared by adopting a microbial fermentation mode, the molecular weight of the polypeptide is reduced, digestion and absorption are facilitated, meanwhile, the yield and oxidation resistance of the peptide are improved by adopting the microbial fermentation mode, the highest yield can reach 45.5%, and the highest oxidation resistance can reach 72.5%; besides, isomaltulose is also added while the bovine bone collagen peptide powder, the ginseng peptide powder and the peony peptide powder are adopted, so that the taste of the product is improved, the reconstituability of the product is improved, the fluctuation of blood sugar and insulin level is not caused after the product is taken, and the product can also be drunk by diabetics.

The invention relates to the technical field of molecular biology, in particular to a methylation marker for diagnosis of diabetic nephropathy. Specifically, the methylation marker comprises a P site of a CAT gene promoter region and / or an E site of a CAT gene exon 1 region. Based on a detection system combining methylation sensitive restriction enzyme with quantitative PCR, the kit has the advantages of simplicity and convenience in operation, good repeatability, accuracy in quantification and easiness in standardization, and is suitable for low-invasive samples such as peripheral blood. By effectively distinguishing pure type 2 diabetes patients from diabetic nephropathy combined patients, a reliable technical means is provided for risk stratification, early intervention and dynamic monitoring of diabetic people, and the method has good clinical application prospects and popularization value.

The utility model relates to nursing instrument technical field, and disclose a kind of diabetic foot protection device, including protection device bottom pad, the top of protection device bottom pad is equipped with flexible protection body, the side of protection device bottom pad is equipped with rotating shaft, the side of rotating shaft is rotatably connected with hard protection body, the side of protection device bottom pad is fixedly connected with first connecting block, the side of hard protection body is fixedly connected with connecting plate, the top of first connecting block is equipped with the insertion slot, the top of connecting plate is fixedly connected with second connecting block, the one end of second connecting block is equipped with structure slot.The foot protection device for lower limb nursing of diabetic patient can make medical staff more conveniently observe and replace the wound dressing of affected side toe, help to prevent disease from getting worse, and improve the efficiency of nursing work, at the same time, it reduces the discomfort of patient suffered from repeatedly wearing protection device.

The invention provides a preparation method of steamed buns capable of improving frozen storage quality and slowing down postprandial blood sugar generation. The preparation method comprises the following steps: (a) preparing the following raw materials in parts by weight: 103-187 parts of plain flour, 70-110 parts of pitaya, 35-55 parts of radix puerariae powder, 5-25 parts of hericium erinaceus powder, 3-7 parts of yeast and 20-60 parts of water; (b) mixing the plain flour, the kudzuvine root powder and the hericium erinaceus powder, adding the crushed pitaya, the activated yeast and the water, and performing dough kneading to obtain dough; and (c) sequentially performing primary fermentation, shaping, secondary fermentation and steaming on the dough to obtain the steamed bun. According to the present invention, the formula is matched with the preparation process, such that the prepared steamed bun has characteristics of thick taste, high resilience, low-temperature storage benefiting, low-temperature storage, low hardening rate after low-temperature storage and reheating, small moisture content change, and after-meal sugar increasing coefficient reducing; and the product is more suitable for being developed into long-term food for diabetics to eat.

The invention relates to the technical field of machine learning medical prediction, in particular to a diabetes-related pancreatic cancer risk prediction method based on a machine learning model and biological age, and the method comprises the steps: constructing a health reference population queue and a type 2 diabetes application verification queue; determining a core index panel through an automatic machine learning process, and training by adopting a regularization survival analysis model to obtain biological age and age acceleration; based on multi-modal features such as age acceleration, predicting a future pancreatic cancer absolute risk probability by using a machine learning competitive risk model, performing risk grade division, calculating an equal-risk age and supporting risk trajectory simulation according to the future pancreatic cancer absolute risk probability; and packaging the model into a risk prediction toolkit with an adaptive calibration function, and outputting a comprehensive risk assessment report. According to the method, the biological age is trained by adopting the pure health queue, so that the interference of the disease state on aging measurement is avoided, and the prediction precision of the pancreatic cancer risk of the type 2 diabetes mellitus population is improved.

The application discloses a diabetes patient biological age calculation method based on glycosylation markers and a multi-task deep learning framework, and belongs to the technical field of bioinformatics and medical data processing technology, and the method comprises the following steps: obtaining glycomics feature data and clinical examination data of diabetes patients; preprocessing the data; obtaining a feature set by adopting a multi-method screening and fusion strategy; constructing a deep learning model comprising a multi-modal feature fusion module and a multi-task learning module for training, wherein the multi-task learning module comprises a main task of aging clock regression and at least one auxiliary task; and outputting biological age prediction values and age acceleration evaluation results of individuals by using the trained model. The method realizes deep fusion of multi-modal biological data and exclusive modeling for the diabetes population, can accurately quantify the biological aging process and the deviation degree relative to the calendar age, and provides an objective quantitative tool for clinical evaluation.

The invention relates to a pharmaceutical composition kit for controlling blood sugar. The pharmaceutical composition kit comprises an oral insulin enteric capsule and a ketoester oral liquid or a ketoester capsule. The insulin enteric capsule is orally taken before sleep, so that fasting blood-glucose at night and in the morning can be well controlled. The ketoester oral liquid is taken before meals in daytime, so that a human body enters a ketogenic state, the blood sugar is reduced, and the postprandial blood sugar peak can be avoided. The combination of the two medicines can realize better control of human blood sugar. Furthermore, ketone ester can enhance insulin sensitivity and enhance the heart function of the diabetic patient. The kit is low in cost and good in sugar control effect, and is an ideal sugar control scheme for diabetics at present.

The invention provides a nutrition dynamic optimization method and system based on multi-model fusion, and relates to the technical field of nutrition health and artificial intelligence, and the method comprises the steps: carrying out the blood glucose prediction based on the comprehensive data of a user, generating a blood glucose prediction sequence, carrying out the key metabolic path node recognition based on the comprehensive data, and obtaining a node activation distribution vector. Calculating a metabolic elasticity index based on the comprehensive data and the node activation distribution vector, optimizing a dietary fiber threshold value of the user based on the metabolic elasticity index and the comprehensive data, generating various nutrition schemes based on the metabolic elasticity index, the blood glucose prediction sequence, the node activation distribution vector and the comprehensive data, and calculating the dietary fiber content of the nutrition schemes. Calculating the difference value between the dietary fiber threshold value and the dietary fiber threshold value, arranging the difference value in an ascending order, and outputting the first nutrition scheme. Through multi-omics linkage and dynamic optimization of the metabolic elasticity index, accurate matching of nutrition intervention and real-time physiological status and flora characteristics of the user is realized, and a personalized scheme is provided for diabetic people.

The invention relates to a method for realizing automatic recipe recommendation based on personalized parameter setting. The method comprises the following steps: inputting the age, gender, height, weight and labor type of a patient, the diagnosis of a current doctor and the type of food to be forbidden; a recipe suitable for the patient is judged, and if the patient is a diabetic patient, a food exchange method is selected; if the patient is a weight losing group, selecting a combined calculation method of basic metabolism BMR and daily consumption TDEE; and automatically generating a recipe menu through the large model according to the recipe cycle needing to be recommended and the careful degree of recipe recommendation. By adopting the method and the device for realizing automatic recipe recommendation based on personalized parameter setting, the processor and the computer readable storage medium thereof, through intelligent and personalized diet management, the requirements of a patient are accurately met, meanwhile, the calculation process is simplified, a scientific and reasonable diet plan is automatically generated, and diet diary records are cooperated, so that the user experience is improved. And the diet management efficiency and effect are greatly improved.

The utility model discloses a special acupoint physiotherapy instrument for diabetics, which relates to the technical field of physiotherapy equipment, and comprises a box body, the left side and the right side of the top of the box body are both provided with openings, the left side and the right side of the interior of the box body are both provided with sliding blocks in a sliding mode, and the opposite ends of the two sliding blocks are both provided with massage wheels in a rotating mode. The two massage wheels are located under the two openings respectively. The bottom of the inner side of the box body is fixedly provided with a telescopic support, the top of the telescopic support is fixedly provided with a double-shaft motor, the double-shaft motor is located between the two massage wheels, and the double-shaft motor is in transmission connection with the two massage wheels. According to the massage wheel, the foot sole acupuncture points of a patient can be continuously pressed through the balls on the outer surface, so that the massage effect is achieved, the foot sole acupuncture points of the patient can be comprehensively pressed through continuous movement of the multiple balls, the massage wheel is suitable for patients with feet of different sizes, and the good massage effect can be achieved.

This invention relates to the field of functional beverage technology, specifically to a functional beverage containing willowherb water extract, its preparation method, and its application. The beverage comprises the following components in the indicated mass-volume ratios: willowherb water extract dry extract 0.6-1.8 g / 30 mL, fructooligosaccharides 1.2-3.6 g / 30 mL, citric acid 0.06-0.18 g / 30 mL, xanthan gum 0.036-0.084 g / 30 mL, and L-ascorbic acid 0.03-0.15 g / 30 mL. While ensuring excellent color, flavor, and taste, the beverage achieves low sugar content, suitable acidity, and good stability, making it suitable for a wide range of consumers, including those with diabetes. The beverage preparation process is simple and reproducible, facilitating standardized production and large-scale promotion. It provides a feasible path for the high-value development of willowherb resources. Fructooligosaccharides hardly participate in sugar metabolism and do not raise blood sugar. The combination of willowherb's sleep-aiding function and low sugar content makes it suitable as a nighttime beverage for diabetic patients.

The utility model discloses a quantitative dinner plate for diabetics, which belongs to the technical field of diabetes nursing and comprises a dinner plate. The inner side of the dinner plate is connected with a quantitative separation mechanism; a soup plate is arranged on the left side of the dinner plate; the right side of the dinner plate is provided with a fruit plate; the lower end of the dinner plate is connected with a portable carrying mechanism for placing the dinner plate, the soup plate and the fruit plate; the quantitative separation mechanism comprises a separation assembly and a fixed-point fixing assembly; the separating assembly used for separating the inner side of the dinner plate into three parts is connected to the inner bottom of the dinner plate. The fixed-point fixing assembly used for conducting fixed-point positioning on the separation assembly is connected to the upper end of the separation assembly. By means of the mode, the inner side of the dinner plate is divided into the three cavities with different proportions through the partition assembly according to the doctor's advice, the partition assembly is fixed through the fixed-point fixing assembly, rice, vegetable dishes and meat dishes are placed in the three cavities respectively, quantitative control over diet is achieved, the proportion of the three cavities can be adjusted, and the food can be conveniently taken out. The requirements of different diabetics on different quantification standards are met.

The invention discloses hypoglycemic milk powder as well as a preparation method and application thereof. Relates to the technical field of food processing. Comprising the following raw materials: degreased raw milk, demineralized whey powder, concentrated whey protein powder, Xinjiang Tianshan cichorium intybus cell exosome freeze-dried powder, trehalose, fructo-oligosaccharide, calcium carbonate, multivitamins, chitosan, sodium alginate, maltodextrin and the balance of purified water. The blood glucose reducing efficiency is remarkably improved, the stability and the storage period of the exosome are greatly prolonged, and the exosome is adaptive to the physiological needs of people suffering from diabetes and is high in safety and better in brewing performance and taste optimization.

The enzyme takes a low glycemic index as a core design target, adopts three-stage secondary fermentation, and combines low-temperature slow-release enzymolysis, microcapsule targeted slow release and prebiotics synergistic interaction mechanisms, so that the enzyme has the advantages of low glycemic index, low glycemic index, high glycemic index, high glycemic index, high glycemic index, high glycemic index, high glycemic index, high glycemic index and high glycemic index. The formula of the health-care food comprises low-GI fruit and vegetable freeze-dried powder, a high-activity balsam pear saponin compound, mulberry leaf flavone micro-capsules, resistant starch-inulin composite prebiotics, a nattokinase-alpha-glucosidase inhibitory peptide (AGI-P) synergistic system, and gastric acid-resistant lactobacillus plantarum (Lactobacillus plantarum delta ldh-1) subjected to gene editing, and the health-care food is prepared from the low-GI fruit and vegetable freeze-dried powder, the high-activity balsam pear saponin compound, the mulberry leaf flavone micro-capsules, the resistant starch-inulin composite prebiotics and the nattokinase-alpha-glucosidase inhibitory peptide (AGI-P) synergistic system. Through the three-stage process of mother liquor anaerobic fermentation, sub-liquor aerobic fermentation and microencapsulation three-time aging, the bioavailability of active ingredients is improved by 3.2 times, the postprandial blood sugar peak value of the type 2 diabetes mellitus patient can be reduced by 41.7% through clinical verification, the risk of hypoglycemia is avoided, and the clinical application prospect is wide. The invention solves the problems of high sugar increasing load, easy inactivation of active components, low intestinal colonization rate and the like of the existing enzyme, and is suitable for long-term nutrition intervention of diabetics.

The invention relates to diglyceride oil powdered oil suitable for diabetics as well as a preparation method and application of the diglyceride oil powdered oil. The diglyceride oil powder grease comprises the following raw material components in percentage by mass: 8%-20% of sodium caseinate, 8%-20% of corn resistant dextrin, 60%-80% of diglyceride oil and 1%-3% of an emulsifier, the diglyceride oil is prepared from coconut diglyceride oil, soybean diglyceride oil and linseed diglyceride oil. The diglyceride oil powder grease can inhibit postprandial blood sugar and blood fat from rising, is high in oil content and embedding rate and low in surface oil content, and can be used as a fat component of special medical food for diabetics.

The invention relates to a preparation method of white tea and konjak vermicelli suitable for diabetics, which comprises the following steps: 1) taking aged white tea, crushing to obtain white tea superfine powder, adding purified water into the white tea superfine powder, uniformly stirring, and adding polyphenol oxidase for enzymolysis to obtain white tea flavor powder; (2) pulping fresh konjak tubers to obtain fresh konjak pulp; 3) uniformly stirring the fresh konjak pulp, the white tea flavor powder, the oat beta-glucan, the potassium alginate and the water to obtain a mixed colloid, and then preparing the mixed colloid into strips; and 4) curing, shaping, drying and packaging the strips to obtain the white tea and konjak vermicelli. The prepared white tea and konjak vermicelli is extremely low in glycemic index (GI) value, and is suitable for being used as a staple food substitute for diabetics; meanwhile, various active ingredients such as dietary fibers and tea polyphenols are rich, so that oxidation resistance and intestinal health regulation are facilitated. The white tea and konjak vermicelli prepared by the method perfectly combines the mellow fragrance of white tea and the taste of konjak, and is smooth and chewy in taste and free of bad fishy and alkaline taste.

1. Name of the product in this design: Dosage Rotary Knob. 2. Purpose of this product design: It is mainly used for insulin injection by diabetic patients. The dosage knob is used to adjust the injection dose when the injection pen is started. 3. The key design features of this product are the combination of shape and pattern. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The invention discloses an inonotuso bliquus (Fr) Pilat compound beverage, and belongs to the technical field of tea drinks. The inonotuso bliquus pilat making method comprises the following steps: after an inonotuso bliquus pilat raw material is selected, dandelion is poured into a basin to be cleaned and washed with running water for 2 min, and then the inonotuso bliquus pilat is wrung out with two hands as much as possible; crushing the wrung inonotuso bliquus by using a crusher; grinding the crushed inonotuso bliquus by using a grinding disc for 5 minutes until the inonotuso bliquus is changed into powdery particles from crushed residues; the compound solid beverage is prepared from the inonotuso bliquus and the carrots, integrates microorganisms and traditional Chinese medicine extracts, is purely natural, healthy and nutritional, and has the characteristics of light weight, small volume, convenience in carrying, good instant solubility, convenience in drinking, simplicity in packaging, convenience in transportation and the like. The composite solid beverage disclosed by the invention is dark brown in color, has coffee fragrance, is fresh and sweet in taste, convenient to carry and easy to brew, is particularly suitable for diabetics to drink, and has a health-care effect of reducing blood sugar.

1. The name of the design product: cap. 2. The use of the design product: for diabetes patients to inject insulin, to start the injection pen and protect the needle. 3. The design points of the design product: the combination of shape and pattern. 4. The picture or photo that best indicates the design points: perspective view.

The invention discloses an exhaled gas ketone body detection method based on PTR-TOF-MS. The exhaled gas ketone body detection method and electronic equipment belong to the technical field of medical detection.The exhaled gas ketone body detection method comprises the steps that S1, exhaled gas samples of urinary ketone body positive and urinary ketone body negative subjects are collected; s2, carrying out acetone concentration determination on each collected exhaled gas sample by virtue of PTR-TOF-MS equipment; s3, analyzing the relationship between the concentration of acetone in the exhaled gas sample and the concentration of uroketones and blood beta-hydroxybutyric acid; and S4, drawing a working characteristic curve of the subject by taking uroketoneme positive as a diagnostic gold standard, and finding out an acetone concentration tangency point value for diagnosing that the expired gas ketoneme positive. The acetone concentration of exhaled gas is analyzed on the basis of PTR-TOF-MS, the ketone metabolism condition in the body is reflected through real-time, rapid and accurate detection of the acetone concentration of exhaled gas, compared with traditional blood beta-hydroxybutyric acid determination, the method is noninvasive, meanwhile, the hysteresis quality of uroketones detection is made up, and the detection accuracy is high. The method is of positive significance to real-time evaluation of glycolipid metabolism of all people, especially diabetes people.

The present application relates to the technical field of diabetes risk assessment, and discloses a diabetes risk assessment method and system, comprising: collecting user data, obtaining a diabetes diagnosis standard, and performing crowd determination according to the user data and the diabetes diagnosis standard; establishing a life correction model, a glycation deviation model and a glycosylation accumulation model, processing the user data to obtain analysis data; when the crowd determination is a non-diabetes crowd, establishing an onset evaluation model, the onset evaluation model calculating a basic risk score based on the life correction model, correcting the basic risk score through onset condition auditing to obtain a glycosylation corrected risk score, and mapping the glycosylation corrected risk score to an onset risk grade; when the crowd determination is a diabetes crowd, establishing a control evaluation model, the control evaluation model calculating a basic control risk grade based on the life correction model and the glycosylation accumulation model, and correcting the basic control risk grade through control condition auditing to obtain a control risk grade.

The invention discloses a carbon dot-coated phosphorus-aluminum zeolite room-temperature phosphorescent material as well as a preparation method and application thereof, and the preparation method comprises the following steps: taking a mixed aqueous solution of boric acid and ethylenediamine as a carbon dot precursor, taking aluminum-based zeolite as a confinement matrix, and synthesizing the carbon dot-coated phosphorus-aluminum zeolite through a blending heating method. Based on the long-life phosphorescent property of the material, when the material is used for time-resolved detection of 3-NT in urine of a diabetic patient, interference of short-life background fluorescence in a biological sample can be effectively avoided. Based on room-temperature phosphorescent induced TMB catalytic discoloration, colorimetric sensing of TAC in urine is realized, and compared with existing TAC detection technologies (such as DPPH, FRAP and ABTS methods), the TAC content in urine can be rapidly, simply, conveniently and visually detected. According to the dual-mode sensing strategy of 3-NT and TAC, simultaneous verification of multi-dimensional biomarkers in urine is realized, and a new way is provided for diabetes screening based on rapid and non-invasive urine analysis.