144 results about "Spatial localization" patented technology

A device, method and process for three-dimensional spatial localization and functional interconnection of the same or different types of cells. The two or three-dimensional device comprising multiple layers containing wells for cell deposition where both the wells and layers are interconnected through microfluidic channels. A process for fabricating the three-dimensional device and a method for depositing different types of cells within the device in a functional interdependent spatial orientation thereby mimicking physiological functions. The device is useful for diagnostic assays, determination of dysfunction of certain cells in the system, quantification of production of cellular proteins, metabolites, hormones or other cellular products, for organ or tissue replacement, for co-culturing different cells, for testing pharmaceutical agents and as a bioreactor for production of biologicals.

Nitrogen vacancies in bulk diamonds and nanodiamonds can be used to sense temperature, pressure, electromagnetic fields, and pH. Unfortunately, conventional sensing techniques use gated detection and confocal imaging, limiting the measurement sensitivity and precluding wide-field imaging. Conversely, the present sensing techniques do not require gated detection or confocal imaging and can therefore be used to image temperature, pressure, electromagnetic fields, and pH over wide fields of view. In some cases, wide-field imaging supports spatial localization of the NVs to precisions at or below the diffraction limit. Moreover, the measurement range can extend over extremely wide dynamic range at very high sensitivity.

An optical transport system configured to transmit a set of two or more optical variants per bit-word, with the optical variants in the set being different from one another in one or more of the time of transmission, spatial localization, polarization of light, carrier wavelength, and subcarrier frequency. Differences between the optical variants may also be due to different respective constellation mapping. The optical variants of each set are detected and processed at the receiver in a manner that enables coherent summation of the corresponding electrical signals prior to constellation de-mapping. The coherent summation tends to average out the deleterious effects of linear and nonlinear noise/distortions imparted on the individual optical variants in the optical transport link because said noise/distortions are incoherent in nature. A BER reduction enabled by the use of optical variants may be implemented in addition to or instead of that provided by FEC coding.

An optical transport system configured to transmit at least two phase-conjugated optical variants carrying the same modulated symbols, with the phase-conjugated optical variants in being different from one another in one or more of polarization of light, the time of transmission, spatial localization, optical carrier wavelength, and subcarrier frequency during transmission. The two phase-conjugated optical variants can be generated by a single polarization-diversity transmitter to be orthogonally polarized, and propagate through an optical transmission link with the same wavelength and spatial path. The optical variants are detected and processed at the receiver in a manner that enables coherent summation of the corresponding electrical signals prior to constellation de-mapping. The coherent summation tends to cancel out the deleterious effects of nonlinear distortions imparted on the individual phase-conjugated optical variants in an optical fiber transmission link because said nonlinear distortions tend to be opposite to each other.

A multichannel source activity detection system, e.g., a voice activity detection (VAD) system, and method that exploits spatial localization of a target audio source is provided. The method includes the steps of receiving a mixed sound signal by at least two microphones; Fast Fourier transforming each received mixed sound signal into the frequency domain; filtering the transformed signals to output a signal corresponding to a spatial signature of a source; summing an absolute value squared of the filtered signal over a predetermined range of frequencies; and comparing the sum to a threshold to determine if a voice is present. Additionally, the filtering step includes multiplying the transformed signals by an inverse of a noise spectral power matrix, a vector of channel transfer function ratios, and a source signal spectral power.

An apparatus comprises an optical transmitter that comprises a processor and at least one optical modulator. The processor is configured to generate electronic representations of at least two pre-dispersion-compensated phase-conjugated optical variants carrying a same modulated payload data for transmission. The at least one optical modulator is configured to modulate the electronic representations, wherein an amount of dispersion induced on the pre-dispersion-compensated phase-conjugated optical variants depends on an accumulated dispersion (AD) of a transmission link through which the pre-dispersion-compensated phase-conjugated optical variants are to be transmitted. The amount of dispersion induced on the phase-conjugated optical variants may be approximately −AD/2, where AD is the accumulated dispersion of the transmission link. The pre-dispersion-compensated phase-conjugated optical variants are different from one another in one or more dimensions such as the polarization of light, the time of transmission, the spatial localization, the optical carrier wavelength, or the subcarrier frequency during transmission.

The present invention is directed to novel tissue protective peptides. The tissue protective peptides of the invention may bind to a tissue protective receptor complex. In particular, the present invention is drawn to tissue protective peptides derived from or sharing consensus sequences with portions of cytokine receptor ligands, including Erythropoietin (EPO), that are not involved in the binding of the ligand to the receptor complex, e.g., to the EPO receptor homodimer. Accordingly, the tissue protective peptides of the invention are derived from the amino acid sequences of regions of cytokine receptor ligands that are generally located on or within the region of the ligand protein that is opposite of the receptor complex, i.e., are generally derived from amino acid sequences of regions of the ligand protein that face away from the receptor complex while the ligand is bound to the receptor. The invention is further directed to the consensus sequences for use in engineering a synthetic tissue protective peptide. These tissue protective peptides also include fragments, chimeras, as well as peptides designed to mimic the spatial localization of key amino acid residues within the tissue protective receptor ligands, e.g., EPO. The invention further encompasses methods for treating or preventing a disease or disorder using tissue protective peptides of the current invention. The invention also encompasses methods for enhancing excitable tissue function using tissue protective peptides of the current invention.

The invention discloses a LabVIEW-based (laboratory virtual instrumentation engineering workbench based) microphone array sound source localization method and device. The method includes the steps of building a microphone array; acquiring microphone data signals; calculating differences of time which sound of a sound source takes to reach to microphone sensors at different positions; localizing the sound source according to the differences of time. The method and the device have the advantages that three-dimensional spatial localization of sound sources is achieved by the use of a microphone array, sound source localization precision is improved, interference of uninterested sounds such as noise is effectively inhibited, the differences of time which the sound of the sound source takes to reach to the microphone sensors at the different positions are calculated, calculation complexity is reduced, and timeliness of a pickup system is improved.

Methods of aligning single walled carbon nanotube structures into selected orientations for a variety of different applications are achieved by initially dispersing the nanotube structures in aqueous solutions utilizing a suitable dispersal agent. The dispersal agent coats each individual nanotube structure in solution. The dispersal agent may be substituted with a suitable functional group that reacts with a corresponding binding site. Dispersed nanotube structures coated with substituted dispersal agents are exposed to a selected array of binding sites such that the nanotubes align with the binding sites due to the binding of the substituted functional groups with such binding sites. Alternatively, crystalline nanotube material is formed upon deposition of dispersed nanotube structures within solution into channels disposed on the surface of the substrate. Combining dispersal agent chemical modification techniques with deposition of the nanotubes into substrate channels is also utilized to produce useful structures.

Disclosed is an image registration and an augmented reality system and an augmented reality method thereof which is suitable for solving the problem of spatial localization of the temporomandibular joint (TMJ) in arthroscopic surgery. The system comprises a three-dimensional scanning model building device, a stereoscopic image photographing device, a projection device and an arithmetic unit. The three-dimensional scanning model was constructed by preoperative or intraoperative imaging of the patient, and the surface three-dimensional model constructed by the stereoscopic image photographing device was spatially aligned to remove the surface (skin layer) of the three-dimensional image to display the TMJ image. Through the calibration of the stereoscopic image photographing device and the projection device, accurate, three-dimensional TMJ image location information is projected onto the patient's body to achieve the purpose.

The invention relates to the field of spatial orientation, in particular to a movement trail recording and redrawing system based on the BeiDou navigation satellite system. According to the movement trail recording and redrawing system based on the BeiDou navigation satellite system, a BeiDou navigation satellite module, a single-chip microcomputer control module, a data storage module and an USB interface are connected in sequence, and a mode selection key and a display module are connected with the single-chip microcomputer control module; positioning information including UTC time, the longitude, the latitude, the number of satellites, the speed, the height and the like can be displayed according to needs of an exerciser, after movement is ended, the positioning information is loaded into a computer through the USB interface, and a movement trail is redrawn on a map according to a Gaussian projection formula transformation coordinate system combined with map data; the movement speeds on different road sections at different times can be displayed, and therefore the exerciser is helped to make an exercise plan according to the actual condition of the exerciser. In addition, the movement trail recording and redrawing system based on the BeiDou navigation satellite system can also be applied to research, development and testing of transportation tools such as an automobile, a ship and an airplane and can assist in equipment calibration and machine debugging.

Described herein is a system for inferring one or a population of biochemical interaction networks, including topology and chemical reaction rates and parameters, from dynamical or statical experimental data, with or without spatial localization information, and a database of possible interactions. Accordingly, the systems and methods described herein may be employed to infer the biochemical interaction networks that exist in a cell. To this end, the systems and methods described herein generate a plurality of possible candidate networks and then apply to these networks a forward simulation process to infer a network. Inferred networks may be analyzed via data fitting and other fitting criteria, to determine the likelihood that the network is correct. In this way, new and more complete models of cellular dynamics may be created.

The invention discloses a method for constructing a special-shaped thin shell of a concrete structure. The method includes the following steps of firstly, conducting spatial localization, setting up a three-dimensional model of the special-shaped thin shell, sectioning the model to form slices, setting up a database of coordinates of all the slices, taking intersection points of the horizontal cross section and the sectioning face as control points, forming a database of coordinates of the control points, and conducting surveying and lining; secondly, erecting a formwork, wherein the formwork comprises a supporting frame arranged inside, a main keel arranged on the supporting frame, an auxiliary keel arranged on the main keel, and a formwork, and the auxiliary keel is covered with the formwork; thirdly, conducting reinforcing bar engineering, namely, setting reinforcing bars outside the formwork, and forming a reinforcement fabric; fourthly, conducting concrete construction, namely, pouring concrete on site in different areas and different sections to form the thin shell; fifthly, removing loads from the body of the thin shell and conducting monitoring at the same time. The formwork which forms the special-shaped thin shell after construction is conducted is formed with modeling wood, and the shape and the stress condition of the formed special-shaped thin shell of the concrete structure meet the design requirements.

Methods and devices for achieving spatial positioning of an RFID tag, a 3D signature and man-machine interaction are provided. The method for achieving spatial positioning of an RFID tag comprises the steps of: arranging at least three groups of array antennas which are distributed in a three dimensional form on electronic equipment, wherein each group of array antennas comprises a plurality of antenna array elements extending on one dimension; starting an RFID tag reader to generate a radio frequency electromagnetic field when spatial positioning of the RFID tag is performed; acquiring an induced voltage generated by each antenna array element in each group of array antennas when inducting that there is an RFID tag in the radio frequency electromagnetic field; and determining spatial position information of the RFID tag according to the induced voltage. Based on the method and the device for achieving spatial positioning of the RFID tag, the present invention also provides methods and devices for achieving 3D signature and man-machine interaction. Through adoption of the methods and the devices, the RFID tag can be used for achieving spatial signature, from a planar handwriting to a spatial handwriting, security coefficient of the signature can be improved.

A nuclear imaging apparatus (8) acquires nuclear imaging data comprising events wherein each event records at least spatial localization information and a timestamp for a nuclear decay event. An event-preserving image reconstruction module (22) reconstructs the nuclear imaging data using an event-preserving reconstruction algorithm to generate an image represented as an event-preserving reconstructed image dataset (ID) comprising for each event the timestamp and at least one spatial voxel assignment. One or more structures are identified in the image and independent motion compensation is performed for each structure. In one approach, an events group is identified corresponding to the structure comprising events assigned to the structure by the event-preserving reconstructed image dataset; a time binning of the events of each events group is optimized based on a motion profile for the structure; time bin images are generated; and the structure is spatially registered in the time bin images.