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56 results about "Intraoperative imaging" patented technology

The intraoperative magnetic resonance imaging (the iMRI) gives neurosurgeons real-time views of the brain during surgery, allowing them to detect abnormal tissues and remove brain tumors safely and effectively. Intraoperative imaging during surgery enables neurosurgeons to operate more precisely.

Integrated ai-powered adaptive robotic surgery system

A robotic surgical system includes a robotic manipulator configured to perform surgical procedures under direct surgeon control. A surgical camera system captures real-time intraoperative video. An external imaging interface receives multimodal imaging data, including preoperative and intraoperative data from at least one of magnetic resonance imaging (MRI), computed tomography (CT), ultrasound, and fluoroscopy. An artificial intelligence (AI module has a trained neural network and a deep learning model trained on multi-institutional annotated surgical datasets, The AI module is configured to execute one or more of: fuse acquired video and imaging data into temporally and spatially coherent anatomical visualizations; generate continuously updating overlays aligned with the surgical field, with segmented anatomical features; projected tissue boundaries, proximity indicators for instruments, and predictive deformation trends; provide dynamic predictive trend visualization indicating zones of future anatomical complexity or risk; register and align preoperative imaging data with intraoperative imaging data in real time; adapt overlay presentation in response to tissue deformation without actuating the robotic manipulate or; and passively augment visual feedback without initiating any autonomous actuation of surgical instruments.
Owner:BRUBAKER WILLIAM +1

Artificial intelligence assisted intraoperative imaging method and system and storage medium

The invention relates to the technical field of medical image processing, in particular to an artificial intelligence assisted intraoperative imaging method, which comprises the following steps: S1, preprocessing a multi-modal medical image, segmenting and recognizing an anatomical structure by a deep learning model according to the preprocessed image, measuring anatomical parameters based on a segmentation and recognition result, and generating an operation planning path by artificial intelligence according to the anatomical parameters; s2, collecting a C-shaped arm perspective image stream in real time, dynamically tracking space coordinates of a surgical instrument, comparing the position of the instrument with a surgical planned path, calculating offset, and when the offset is greater than an offset threshold, outputting correction guidance through an AR superposition layer; and S3, monitoring an image quality index in real time, dynamically adjusting exposure parameters through a reinforcement learning model, and when a metal implant is detected, switching a dual-energy-spectrum mode and executing an artifact suppression algorithm. According to the method, preoperative precise planning and intraoperative assistance are realized through artificial intelligence, the problems of poor image quality and high radiation risk are solved through technical optimization, and the method has important clinical application value.
Owner:SHANGHAI DROIDSURG MEDICAL CO LTD +1

System and method for generating an initial transformation matrix for registering intraoperative imaging data with preoperative imaging data

Various systems and methods are provided for generating an initial transformation matrix for registering intraoperative imaging data with preoperative imaging data. Position data of a tracked instrument that is moved in a trajectory corresponding to a predefined shape relative to a patient may be received. A first set of coordinates of the position data corresponding to the predefined shape may be determined. Preoperative imaging data of the patient may be received. A second set of coordinates of the preoperative imaging data corresponding to the predefined shape may be determined. The initial transformation matrix may be generated based on the first set of coordinates and the second set of coordinates. The intraoperative imaging data may be registered with the preoperative imaging data based on the initial transformation matrix.
Owner:GE PRECISION HEALTHCARE LLC

Target organ model registration method and system, electronic equipment and storage medium

The embodiment of the invention provides a target organ model registration method and system, electronic equipment and a storage medium, and belongs to the technical field of surgical navigation, and the method comprises the steps: obtaining target organ image data of a patient before an operation, and constructing a corresponding preoperative three-dimensional point cloud model based on the target organ image data; the method comprises the following steps: scanning target organ data of a patient in an operation to obtain image data in the operation, and constructing a corresponding three-dimensional point cloud model in the operation based on the image data in the operation; rigid body transformation parameters of the preoperative three-dimensional point cloud model and the intraoperative three-dimensional point cloud model are determined through an ICP registration algorithm, and the preoperative three-dimensional point cloud model and the intraoperative three-dimensional point cloud model are registered based on the rigid body transformation parameters. The embodiment of the invention aims at improving the real-time performance and the accuracy of target organ model registration, and further improving the accuracy and the real-time performance of surgical navigation.
Owner:THE FIRST AFFILIATED HOSPITAL OF MEDICAL COLLEGE OF XIAN JIAOTONG UNIV

Mueller matrix polarization imaging device based on polarization state synchronous monitoring

The application discloses a Mueller matrix polarization imaging device based on polarization state synchronous monitoring, and aims to solve the problem of slow imaging speed in traditional Mueller matrix polarization imaging technology.The device comprises a light source module, a polarization state generation module, a sample module, a polarization state analysis module, a photoelectric detection module, a synchronous monitoring module and an upper computer module.In the application, the polarization modulation elements of the polarization state generation module and the polarization state analysis module are set to continuous modulation, and the photoelectric detection module is set to continuous acquisition; the polarization state of the polarization modulation elements and the acquisition state of the photoelectric detection module are monitored with high precision through the synchronous monitoring module; and the complete Mueller matrix image of the measured sample is calculated in the upper computer module.The application realizes high-speed dynamic polarization imaging by utilizing continuous polarization state modulation, has high spatial resolution and high measurement precision, and is suitable for real-time polarization observation in the fields of biomedicine, material and industrial detection.
Owner:EAST CHINA NORMAL UNIV

Style transfer for intraoperative imaging

A system receives a set of two-dimensional projection images associated with respective projection angles from an imaging device. The projection images include projections of an anatomical structure, an anatomical target, and possibly fiducial markers, with a flexible elongate device disposed therein. The system can reconstruct a three-dimensional image from the set of two-dimensional projection images. In some examples, prior to reconstruction, the system can detect and repair pixels (within the projection images) associated with the fiducial markers, the flexible elongate device, and / or other objects. The system can enhance the reconstruction using a style transfer model. The system or another system can train the style transfer model by generating two-dimensional projections for a training set based on three-dimensional ground truth images.
Owner:INTUITIVE SURGICAL OPERATIONS INC

Generation of three-dimensional scans for intraoperative imaging

A system for executing a three-dimensional (3D) intraoperative scan of a patient is disclosed. A 3D scanner controller projects the object points included onto a first image plane and the object points onto a second image plane. The 3D scanner controller determines first epipolar lines associated with the first image plane and second epipolar lines associated with the second image plane based on an epipolar plane that triangulates the object points included in the first 2D intraoperative image to the object points included in the second 2D intraoperative image. Each epipolar lines provides a depth of each object as projected onto the first image plane and the second image plane. The 3D scanner controller converts the first 2D intraoperative image and the second 2D intraoperative image to the 3D intraoperative scan of the patient based on the depth of each object point provided by each corresponding epipolar line.
Owner:UNIFY MEDICAL INC

Three-dimensional (3D) cadmium-zinc-telluride (CZT) detector system for extended reality intrasurgical guidance

Three-dimensional and quick radiation detection via cadmium-zinc-telluride (CZT) detectors enable intraoperative / intrasurgical imaging and guidance with respect to radioactive objects detected within a patient body. Multiple CZT detectors are located around the patient body. An image reconstruction can be performed based on 3D-sensitive detections by the multiple CZT detectors to detect (e.g., and triangulate) a radioactive object within the patient body. Using a detected location of the radioactive object, a virtual representation of the radioactive object is provided in an extended reality (XR) experience that captures the patient body. A user wearing an XR headset may be provided with the XR experience while interacting with the patient body, for example, during a surgery.
Owner:M3D INC

Mueller matrix polarization imaging device based on polarization state synchronous monitoring

The invention discloses a Mueller matrix polarization imaging device based on polarization state synchronous monitoring, and aims to solve the problem of slow imaging speed in the traditional Mueller matrix polarization imaging technology. The device comprises a light source module, a polarization state generation module, a sample module, a polarization state analysis module, a photoelectric detection module, a synchronous monitoring module and an upper computer module. Polarization modulation elements of the polarization state generation module and the polarization state analysis module are set to be in continuous modulation, the photoelectric detection module is set to be in continuous collection, and the polarization state of the polarization modulation elements and the collection state of the photoelectric detection module are monitored in a high-precision mode through the synchronous monitoring module. And a complete Mueller matrix image of the tested sample is calculated on the upper computer module. High-speed dynamic polarization imaging is achieved through continuous polarization state modulation, high spatial resolution and high measurement precision are achieved, and the device is suitable for real-time polarization observation of biomedicine, materials, industrial detection and the like.
Owner:EAST CHINA NORMAL UNIV

System and method for intraoperative neural diagnostics

PCT designated stageWO2026036144A1SensorsDiagnostic recording/measuringMuscle responsePatient data
A system and computer-implemented method for intraoperative assessment of nerve health. A processor determines a nerve function parameter from an electrically evoked muscle response to stimulation proximate to a nerve. The processor generates an individualized, predictive target range by accessing a database of historical patient data, identifying a subset of patients with pre-operative characteristics similar to those of the subject, and defining the target range based on intraoperative nerve function measurements associated with successful post-operative outcomes in that subset. A display presents the determined nerve function parameter relative to the individualized target range to provide real-time guidance. The system can integrate intraoperative imaging to concurrently display anatomical and functional information. A predictive model used to generate the target range is refined over time by incorporating outcomes from additional patients, enabling continuous improvement of the assessment.
Owner:NEURALYTIX LLC

Method and apparatus for tracking intra-operative oct imaging position, surgical microscope system, and storage medium

Disclosed in the present application are a method and apparatus for tracking an intra-operative OCT imaging position, a surgical microscope system, and a storage medium. The method for tracking an intra-operative OCT imaging position comprises: according to a historical position of a surgical instrument in a first coordinate system at a first moment, determining a predicted position of the surgical instrument in a second coordinate system at a second moment, wherein the first coordinate system is used for OCT imaging, and the second coordinate system is used for microscope imaging; according to the predicted position, determining a detected position of the surgical instrument in the second coordinate system at the second moment; and according to the detected position, determining a mapped position of the surgical instrument in the first coordinate system at the second moment, so as to track the intra-operative OCT imaging position.
Owner:TOWARDPI (BEIJING) MEDICAL TECH LTD

Methods and systems for generating simulated intraoperative imaging data of a subject

Described herein are systems and methods for generating an intraoperative fluorescence image of a subject. A system receives an intraoperative white light image of the subject and generates a semantic segmentation mask outlining a tumor in the intraoperative white light image. The semantic segmentation mask is generated by a machine learning model trained using a plurality of training image pairs in which each training image pair includes an intraoperative white light training image and an intraoperative fluorescence training image of a same tissue. An outline of the tumor is extracted from the mask, and an intraoperative fluorescence image is generated based on the outline of the tumor from the mask. An area inside the outline in the generated intraoperative fluorescence image is represented by a first color, and an area outside the outline in the generated intraoperative fluorescence image is represented by a second color.
Owner:STRYKER CORP

System and method for processing combined data stream for surgical robot

A surgical robotic system, the surgical robotic system comprising: a first robotic arm having a first instrument and a first sensor; a second robot arm, which may include a second instrument and a second sensor; a laparoscopic camera configured to capture intraoperative imaging data; and a surgeon console including a handle controller configured to receive a user input for actuating at least one of the first robotic arm or the second robotic arm. The system also includes a controller configured to: control at least one of the first robot arm or the second robot arm based on the user input and a control algorithm; receiving a plurality of data streams, which may include sensor data from the first sensor and the second sensor, operational data, user input data, external visual data, and / or internal imaging data from the laparoscopic camera; predicting an occurrence of an event based on the plurality of data streams; and adjusting the control algorithm based on the predicted occurrence of the event.
Owner:COVIDIEN LP

System and method for intraoperative guidance

A method for intraoperative guidance during a surgical procedure involving a nerve includes receiving real-time image data from an intraoperative imaging modality, the real-time image data depicting anatomical structures within an intracorporeal treatment area including the nerve; determining at least one nerve function parameter indicative of nerve health; and controlling a display device to concurrently present a visual output comprising both a visual representation derived from the real-time image data and a visual indication of the determined at least one nerve function parameter. The concurrently presented visual output facilitates assessment of the nerve relative to the anatomical structures during the surgical procedure.
Owner:NEURALYTIX LLC

Colorization of medical devices in robotic surgery using ai and machine learning

A system for intraoperative medical instrument recognition may receive, from an imaging device positioned inside of a patient, a stream of intraoperative three-dimensional (3D) imaging data that includes anatomy of a patient and a medical instrument. The system may apply a material recognition algorithm to identify one or more objects formed of a predetermined material present in the intraoperative 3D imaging data. The system may apply a shape recognition algorithm to the one or more identified objects to identify the medical instrument. The system may generate a modified intraoperative imaging data stream in real-time with the receiving of the stream of intraoperative 3D imaging data. The modified intraoperative imaging data stream may include a visual characteristic, e.g., a colorization, applied to a region of the intraoperative 3D imaging data corresponding to the at least one identified medical instrument.
Owner:CLEAR BIOPSY LLC

System and method for generating initial transformation matrix for registering intra-operative imaging data with pre-operative imaging data

Various systems (100) and methods (500) are provided for generating an initial transformation matrix for registering intra-operative imaging data with pre-operative imaging data. Position data of a tracked instrument moving along a trajectory corresponding to a predefined shape relative to a patient may be received (510). A first set of coordinates of the position data corresponding to the predefined shape may be determined (520). Preoperative imaging data of the patient may be received (530). A second set of coordinates of the pre-operative imaging data corresponding to the predefined shape may be determined (540). An initial transformation matrix (550) may be generated based on the first set of coordinates and the second set of coordinates. The intra-operative imaging data may be registered with the pre-operative imaging data based on the initial transformation matrix (950).
Owner:GE PRECISION HEALTHCARE LLC

Colorization of medical devices in robotic surgery using ai and machine learning

A system for intraoperative medical instrument recognition may receive, from an imaging device positioned inside of a patient, a stream of intraoperative three-dimensional (3D) imaging data that includes anatomy of a patient and a medical instrument. The system may apply a material recognition algorithm to identify one or more objects formed of a predetermined material present in the intraoperative 3D imaging data. The system may apply a shape recognition algorithm to the one or more identified objects to identify the medical instrument. The system may generate a modified intraoperative imaging data stream in real-time with the receiving of the stream of intraoperative 3D imaging data. The modified intraoperative imaging data stream may include a visual characteristic, e.g., a colorization, applied to a region of the intraoperative 3D imaging data corresponding to the at least one identified medical instrument.
Owner:CLEAR BIOPSY LLC

Systems and methods of assessing breath hold during intraprocedural imaging

A system and method for improving a quality of images for local registration where a position of a sensor is monitored to determine whether a breath hold plateau has been achieved, and following imaging is monitored to determine whether the sensor position has returned to a pre-breath hold position.
Owner:COVIDIEN LP

Systems and methods for intra-operative updating of graphical user interfaces based on intra-operative imaging data

A system includes a display system, an elongate device, a medical instrument, and a control system. The control system is configured to: display intra-operative imaging data of a patient anatomy received from an external imaging system in a graphical user interface (GUI) on the display system; displaying a graphical indicator superimposed on the intraoperative imaging data; registering the intraoperative imaging data with the elongation device; transforming the graphical indicator from the intra-operative imaging data frame of reference to the elongated device frame of reference based on the registration; and providing navigational guidance to guide the elongate device to a target location in the patient anatomy based on the target location of the distal tip of the medical instrument displayed via the graphical indicator. The target location of the distal tip of the medical device is within the deployment range of the device when the elongate device is located at the target location.
Owner:INTUITIVE SURGICAL OPERATIONS INC

Intraoperative navigation system and method and computer equipment

The embodiment of the invention is applicable to the technical field of computer-aided medical technology, image processing technology and intraoperative navigation, and provides an intraoperative navigation system and method and computer equipment, the system comprises the computer equipment, and optical navigation equipment and intraoperative imaging equipment which are connected with the computer equipment, the computer equipment is used for realizing the following intraoperative navigation method: registering a guide image currently acquired by the intraoperative imaging equipment, wherein the guide image is a two-dimensional image acquired in real time in an operation; identifying an established or partially established current surgical channel in the registered guide image; and projecting a planned operation channel into the guide image, and guiding a doctor to adjust the current operation channel according to a projection straight line of the planned operation channel. By the adoption of the system, a doctor can be visually guided to adjust an operation channel in an operation through the guide image, the number of times of X-ray fluoroscopy is reduced, and operation efficiency and accuracy are improved.
Owner:YUANHUA ORTHOPAEDIC ROBOTICS (SHENZHEN) LTD

System for robot-assisted navigation in minimally invasive surgical procedures using real-time instrument localization and tissue mapping

A system for robot-assisted minimally invasive surgical navigation with real-time instrument localization and tissue mapping, comprising: a multi-jointed robotic arm with an end effector configured to hold at least one surgical instrument; a plurality of sensor units operatively connected to the surgical instrument and the robotic manipulator, the plurality of sensor units comprising at least one optical sensor unit, at least one electromagnetic sensor unit, and at least one inertial sensor unit; an intraoperative imaging unit configured to acquire real-time image data of the surgical field; and a data acquisition unit configured to receive signals from the plurality of sensor units and the intraoperative imaging unit.a signal conditioning unit configured to calibrate, synchronize, and reduce noise in the received signals; a processing unit configured to determine the spatial position and orientation of the surgical instrument by fusing data from the optical sensor unit, the electromagnetic sensor unit, and the inertial sensor unit; a registration unit configured to compare the intraoperative image data with the preoperative image data to create a unified anatomical reference; a tissue mapping unit configured to generate a three-dimensional representation of tissue structures based on the intraoperative image data; a navigation control unit configured to calculate instrument trajectories based on the spatial position, orientation, and generated three-dimensional representation;and a visualization unit configured to display in real time the spatial position of the surgical instrument in relation to the mapped tissue structures.
Owner:EASWARI ENGINEERING COLLEGE TAMIL NADU +3

A binocular camera-based graph convolution enhanced real-time tracking method for abdominal organs

The application discloses a kind of based on binocular camera's graph convolution enhancement abdominal organ real-time tracking method, comprising the following steps: collecting data and being marked, preoperative model is constructed and is trained, reconstructs three-dimensional model and is optimized, adopts co-rotating finite element modeling, constructs biomechanical model, carries out preoperative initial registration, eliminates the change between preoperative and intraoperative imaging of patient, extracts a variety of abdominal organ features and matches feature points, carries out intraoperative deformation registration and dynamically tracks feature points, and verifies experimental results;The application efficiently solves the problem of complex deformation of soft tissue, accurately selects key feature points through deep learning algorithm, and creates displacement vector field, provides boundary conditions for biomechanical model in time, can effectively simulate various complex deformations, and can adaptively track the dynamic changes of soft tissue during operation, significantly improve the capture and modeling ability of complex deformation behavior of soft tissue.
Owner:HUAZHONG UNIV OF SCI & TECH

Systems and methods for updating a graphical user interface based upon intraoperative imaging

A system includes one or more processors, a user display, and memory having computer readable instructions stored thereon. The computer readable instructions, when executed by the one or more processors, cause the system to obtain pre-operative image data of anatomical passages of a patient, wherein the pre-operative image data includes a target, display the pre-operative image data including the target in a graphical user interface on the user display, receive intra-operative image data from an imaging system, identify a portion of the intra-operative image data corresponding to an instrument disposed in the anatomical passages of the patient, receive a user selection of a portion of the intra-operative image data corresponding to the target, and update the display of the pre-operative image data including the target in the graphical user interface based on the intra-operative image data.
Owner:INTUITIVE SURGICAL OPERATIONS INC

Surgical robotic system and method for using dithering to adjust transparency of an ar overlay

PCT designated stageWO2025262523A1Image enhancementImage analysisMini invasive surgeryEngineering
A method and system provide intra-operative visualization in robotic-assisted and minimally invasive surgeries through augmented reality (AR) overlays using dithering techniques. The system integrates pre-operative and intra-operative imaging directly into the surgeon's field of view on a stereoscopic 3D screen without obstructing critical anatomical views. Traditional alpha blending methods for AR overlays are computationally intensive. The disclosed dithering approach alternately displays augmented and real pixels to create a semi-transparent effect, preserving the endoscopic view and ensuring patient safety. Transparency is dynamically adjustable using hand controllers, foot pedals, eye tracking, and voice commands. This innovation provides surgeons with critical subsurface anatomical information during procedures, reducing cognitive load and improving surgical outcomes by minimizing the risk of damaging critical structures. The system is compatible with existing surgical robotic platforms, offering an efficient and safe solution for integrating AR in surgical environments.
Owner:COVIDIEN LP

Lockable orthopedic turnover operating bed

The utility model discloses a lockable orthopedic turnover operating bed, which relates to the technical field of operating beds and comprises a telescopic bed body main frame, a control end driving part, a non-control end driven part, a high-strength carbon fiber bed board and a high-strength carbon fiber spine frame. The telescopic bed body main frame is formed by connecting a first base and a second base through a guide rail and a sliding block. A control end driving part, a non-control end driven part, a high-strength carbon fiber bed plate and a high-strength carbon fiber spine frame are mounted on the telescopic bed body main frame, the product can meet various body position requirements in orthopedic surgery, and the bed surface can be perspective and overturned by 360 degrees; the surgical positioning and auxiliary operation requirements of other departments such as trauma and spine surgery can be met, surgical navigation and intraoperative imaging equipment can be seamlessly connected, intraoperative fluoroscopy is reduced, the health of doctors and patients is guaranteed, and necessary conditions are provided for development of high-difficulty orthopedic surgery and minimally invasive orthopedic surgery.
Owner:SHENYANG ZHONGHUI YIDA TECH DEV CO LTD

Real-time refraction-correction for intraoperative oct imaging

Described herein are systems and methods for refraction correction of OCT images configured for intraoperative use, including: a deep-learning model configured to receive a plurality of OCT images; and an imaging device configured to generate the plurality OCT images during an intraoperative procedure; wherein the deep-learning model is configured to map, in real-time, the plurality of OCT images to a two-dimensional vector field over a spatial domain of the plurality of OCT images; wherein the mapping is configured for real-time correction of refraction errors on the plurality of OCT images by employing Snell's law to generate a plurality of refraction-corrected OCT images via the deep-learning model. Other examples are described including features of the deep-learning model uniquely configured for interoperative usage such as an OCT image processing speed of 20Hz-50Hz.
Owner:HORIZON SURGICAL SYSTEMS INC

Generation of three-dimensional scans for intraoperative imaging

A system for executing a three-dimensional (3D) intraoperative scan of a patient is disclosed. A 3D scanner controller projects the object points included onto a first image plane and the object points onto a second image plane. The 3D scanner controller determines first epipolar lines associated with the first image plane and second epipolar lines associated with the second image plane based on an epipolar plane that triangulates the object points included in the first 2D intraoperative image to the object points included in the second 2D intraoperative image. Each epipolar lines provides a depth of each object as projected onto the first image plane and the second image plane. The 3D scanner controller converts the first 2D intraoperative image and the second 2D intraoperative image to the 3D intraoperative scan of the patient based on the depth of each object point provided by each corresponding epipolar line.
Owner:UNIFY MEDICAL INC

Systems and methods for registering an instrument to an image using point cloud data and endoscopic image data

A non-transitory, computer-readable medium storing instructions thereon that, when executed by one or more processors of a computing system, cause the computing system to perform operations comprising: generating a point cloud of coordinate points based, at least in part, on positional sensor data captured using a position sensor, wherein the positional sensor data is associated with one or more positions of a biomedical device within an anatomic region of a patient; receiving first image data of patient anatomy captured using an image capture device positioned within the anatomic region; receiving second image data of the anatomic region, wherein the second image data is generated based, at least in part, on preoperative or intraoperative imaging of the anatomic region; generating a registration between at least a portion of the point cloud with at least a portion of the second image data; and updating the registration based, at least in part, on the first image data.
Owner:INTUITIVE SURGICAL OPERATIONS INC

Navigation of medical instrument based on real-time intraoperative CT imaging using conventional x-ray device

A method of producing high quality 3D CT medical imaging models, real-time, from 2D X-ray images acquired from convention imaging equipment, such as X-ray or C-arm devices, already present in an operating room, thereby obviating the need to bring in, and sterilize, additional equipment presently used for 3D image navigation.
Owner:AVERBUCH DORIAN

A near-infrared long-afterglow luminescent nano probe, a preparation method and application thereof

The application discloses a kind of near-infrared long afterglow luminescent nano probes, its preparation method and application, belong to near-infrared long afterglow material field. With mesoporous silica as template, with zinc acetate, gallium nitrate, tin chloride, chromium acetate, chromium nitrate and yttrium nitrate as doped metal raw materials, long afterglow luminescent core is obtained by reaction and calcination;The outer layer of long afterglow luminescent core is coated with manganese dioxide, to obtain pre-product;Pre-product is surface modified, and coupling target molecule plerixafor, i.e. near-infrared long afterglow luminescent nano probe. The near-infrared long afterglow luminescent nano probe has good biological safety, can be effectively enriched in the tumor area in vivo after mouse tail vein injection, can realize high-sensitivity imaging of multiple small tumors in vivo under red light LED irradiation, and the imaging time is short, suitable for intraoperative imaging, can be used for the imaging of breast cancer tumor model to guide tumor resection.
Owner:XIAMEN INST OF RARE EARTH MATERIALS