A dialyzer module utilizing a nano-porous
ceramic membrane for enhanced
hemodialysis performance, and a method for manufacturing the same, are provided. The dialyzer module may be utilized in an
extracorporeal blood circuit together with pumps, monitors, and / or other components used for
dialysis therapy. The one or more nano-porous
ceramic tubes that serve as the
hemodialysis membrane may comprise aluminum
oxide (
alumina) or
titanium oxide (titania) tubes manufactured by the anodization of aluminum (Al) or
titanium (Ti) tubes in an appropriate acid solution. The nano-porous
ceramic tubes may be produced with a nano-porous wall structure having an average
pore diameter of approximately five to ten nanometers (run). The nano-porous ceramic tubes exhibit a uniform pore size, uniform
pore distribution, high
porosity, and high
hydraulic conductivity, enabling the removal of more middle and
large molecular weight solutes to achieve a performance more comparable to that of an actual
kidney while, at the same time, reducing the undesirable loss of important macromolecules such as
albumin.