35 results about "Brain protection" patented technology

The utility model relates to the technical field of headbands, in particular to a brain protection headband, which is used for surrounding and fixing along the head and comprises a headband body, an application band and an outer band, the application band and the outer band are fixedly connected, and the band surface of the application band is provided with a convex ball used for being applied to the head; the rubber inner pad is used for providing shaping support and is arranged in the headband body, and a third embedding cavity is formed in the rubber inner pad; the sweat-absorbing clamping pad is mounted at the third embedding cavity; according to the brain protection headband, a strip-shaped structure is adopted to replace an existing annular headband, so that the binding force of the headband is convenient to adjust; the shaping capability of the head band can be improved through the rubber inner pad arranged in the head band; in order to improve the wearing comfort, the sweat-absorbing clamping pad is arranged for absorbing sweat; in addition, a convex ball used for being applied to the head is arranged on the belt face of the application belt and can be matched with a strip-shaped structure to adjust the brain pressing force, the adjustability is high, and the application range is wider.

The utility model belongs to the technical field of medical instruments, and particularly relates to a novel brain protection device which comprises a catheter, a balloon conducting tube and a filter screen traction wire are arranged in the catheter, the filter screen traction wire slides in the catheter, one end of the filter screen traction wire is fixedly connected with a filter screen, the filter screen is embedded in the catheter, and the other end of the filter screen traction wire is fixedly connected with the balloon conducting tube. The filter screen is arranged on the balloon conducting tube in a sleeving manner, and the filter screen moves on the balloon conducting tube; through traction of the arranged filter screen traction wire, the filter screen moves to the outside of the catheter and opens in a blood vessel, falling calcified vascular tissue fragments are comprehensively intercepted and filtered, the filter screen traction wire is pulled outwards, the filter screen can be collected into the catheter, the filtered calcified vascular tissue fragments are wrapped, and the calcified vascular tissue fragments are taken out along with the brain protection device. And valve calcification fragments are prevented from blocking brain blood vessels.

The present application relates to the technical field of medical devices, in particular to a brain protection filter assembly, comprising a first frame body and a second frame body connected with the first frame body, the second frame body is provided with a first connecting body for connecting and positioning when the brain protection filter assembly is recovered, the present application has the beneficial effects that the first frame body and the second frame body can simultaneously cover the brachiocephalic trunk artery, the left common carotid artery and the left subclavian artery, ensuring the comprehensiveness of the protection range, in addition, the first connecting body provided on the second frame body can realize the free recovery of the brain protection filter assembly after long-time storage in the patient's body after operation, prolong the foreign body capture time, and improve the efficiency of preventing stroke.

The present application provides a propofol analogue, a preparation method thereof and application thereof in non-narcotic field. The propofol analogue has a structure as shown in general formula (G). The propofol analogue of the present application can greatly reduce or eliminate the affinity to GABA receptor, i.e. weaken or eliminate the narcotic property. It targets specific targets and shows effects in improving sleep, regulating blood pressure, relieving vomiting, resisting depression, protecting heart and brain, etc. (G).

The invention belongs to the technical field of medicine, and discloses a thoracic aorta in-situ fenestration and whole-course brain protection integrated device and method. According to the method, a bundling balloon is formed by a plurality of small balloons, the different small balloons are controlled to be inflated or shrunk under pressure relief, and the angle of a puncture needle is adjusted through the bundling balloon catheter. And the far-end protection umbrella covers the cluster balloon catheter and is used for preventing thrombus from escaping to the far end. According to the invention, the bundling balloon composed of a plurality of small balloons is designed, and the angle of the puncture needle is adjusted by controlling the different small balloons to expand by filling or shrink by releasing pressure, so that the time for an instrument to enter a membrane rupture window is greatly shortened, and the positioning accuracy of a membrane rupture point of the covered stent is improved; meanwhile, a far-end protective umbrella is arranged to prevent thrombus and other foreign matters from escaping to the far end.

The invention relates to compositions comprising urolithins with active agents, particularly compositions comprising urolithins and agents which promote brain health and / or immune health. The invention also relates to such compositions, for use for the treatment or prevention of diseases, disorders and conditions, and for use in non-therapeutic treatments. Example of agents which promote brain health include brain protective agents (for example phosphatidylserine, phosphatidylcholine and / or choline), agents that enhance neurotransmission (for example a nootropic, for example ergothioneine, huperzine, aGPC, taurine and / or L-theanine), agents that promote neurogenesis (for example selenium); and brain essential nutrients (example Vitamin B6, B9, B12, magnesium salts, folic acid and / or L-methylfolate). Examples of agent which promote immune health include quercetin, Elderberry or an extract thereof; a selenium salt; and / or a zinc salt.

The application provides a distal filter brain protection device for use in cardiac surgery, comprising a sleeve with an inlet end and an outlet end; the sleeve is divided into 2-3 sleeve branches at the inlet end; the sleeve contains 2-3 implant sheaths; one implant sheath is introduced from each sleeve branch; the implant sheaths are all led out at the outlet end; the implant sheaths are provided with guide wires, and the front ends of the guide wires are provided with umbrella-shaped filter screen devices; the umbrella-shaped filter screen devices are provided with multiple ultrasonic emission balls containing corner reflectors to enhance the ultrasonic reflection effect of the devices. The distal filter brain protection device of the application can simultaneously provide precise filter implantation and removal for multiple blood vessels, especially two carotid arteries, in cardiac surgery, and the implantation and detailed operation process can be completed under ultrasonic monitoring.

The invention relates to the technical field of medical instruments, and provides a pressure-adjustable craniocerebral protective cap in order to solve the technical problems that bandaging after an existing craniocerebral operation cannot be adjusted in time according to craniocerebral pressure, and the pressure cannot be measured and accurately controlled, the pressure-adjustable craniocerebral protective cap comprises a cap body, an opening is formed in the cap body, the opening is of a folded edge design, and a plurality of through holes are formed in the surface of the cap body; an elastic bridle is arranged on the lower edge of the cap body and is used for adjusting the tightness degree of the cap body; the air bag penetrates through the through hole in the surface of the cap body, and the inner side of the air bag is communicated with a human craniocerebral defect area; the pressure adjusting structure is arranged on the outer side of the air bag, communicates with the interior of the air bag and is used for conducting adaptive adjustment when the pressure of the air bag changes. Self-adaptive adjustment can be carried out according to intracranial pressure changes, meanwhile, the device can be tightly attached to a craniocerebral defect area, and intracranial pressure fluctuation caused by factors such as external pressure changes or slight collision of the head is avoided.

The application discloses a database high-availability cluster brain split protection method and device and medium, belongs to the technical field of database high-availability cluster, and is used for solving the technical problems that the existing PostgreSQL high-availability cluster scheme is prone to cluster brain split, mis-switching and data inconsistency problems in network partition and communication anomaly due to the lack of network topology awareness, communication quality quantification, state cross-verification and hierarchical isolation strategy. The method comprises the following steps: after triggering the master selection process of the current cluster, detecting the communicable nodes in the current cluster; performing multi-dimensional quality perception on the communicable nodes to obtain corresponding node state parameters; performing weighted calculation according to the node state parameters to obtain a weighted value; if the weighted value reaches a first preset threshold, performing visibility consensus verification on each communicable node; after the visibility consensus verification is passed, determining a candidate master selection area based on the regional awareness master selection strategy; and selecting a new master node in the candidate master selection area according to the hierarchical response strategy.

The utility model discloses a brain protection pillow and a cart with the brain protection pillow, the brain protection pillow comprises at least one deformable maintaining part and a pillow part, and the pillow part comprises a bearing unit, two protection units and a containing groove. The two protection units are adjustably arranged on the two opposite sides of the bearing unit respectively, so that the containing groove is formed between the bearing unit and the two protection units and used for containing the head of an infant, and the maintaining part extends from one protection unit to the other protection unit through the bearing unit and is used for maintaining the head of the infant. When force is applied to the protection unit to enable the angle of the protection unit relative to the bearing unit to be adjusted, the maintaining part is stressed and deformed, after external force applied to the protection unit is removed, the maintaining part maintains the angle of the protection unit relative to the bearing unit, and therefore the angle of the protection unit relative to the bearing unit is adjusted. The width size of the containing groove can be adjusted according to needs.

The invention relates to the technical field of medical first-aid equipment, in particular to a device for heatstroke first aid and mild hypothermia treatment. Comprising a foldable cabin body; the composite cooling unit comprises a contact type conduction cooling module, a targeted brain cooling module and an environment convection cooling module; the contact type conduction cooling module is an ice blanket; the targeted brain cooling module is an ice cap, and the environment convection cooling module comprises a cold air inlet formed in the top end of the cabin body, an air outlet formed in the bottom of the cabin body and refrigeration equipment connected with the cold air inlet; and the intelligent monitoring and control unit is connected with the ice blanket, the ice cap and the refrigeration equipment and used for adjusting the temperature of the ice blanket and the ice cap and the cold air output power of the refrigeration equipment. The device provided by the invention integrates cooling, monitoring and brain protection functions, is efficient and cooperative in cooling and accurate in temperature control, can have a brain protection effect, improves the treatment safety, is light and portable, and is suitable for complex environments without fixed medical facilities, such as fields and battlefields.

The application discloses an intraoperative brain protection device, which comprises an elastic support and a filter screen; the elastic support can be self-inflated on the inner wall of a blood vessel of an aortic arch and is attached to the inner wall of the blood vessel of the aortic arch, the elastic support is a ring-like structure surrounded by an elastic metal material, the distal end and the proximal end of the ring-like structure are upwardly curved to fix the intraoperative brain protection device in the aortic arch; the filter screen is located in the area surrounded by the elastic support, and the two ends of the filter screen are connected with the distal end and the proximal end of the ring-like structure respectively to block the thrombus generated in the operation from entering the head artery. The protection device adopts a left subclavian artery approach, compared with a traditional femoral artery protection device, the influence of other femoral artery access instruments on the femoral artery is reduced, the operation effect is guaranteed, and the application of the intraoperative brain protection device in the medical instrument technical field is facilitated.

The utility model discloses a sheathing canal of a multi-conveying system, which comprises a main body tube provided with an intracavitary section inserted into a blood vessel cavity when in use; the main body tube is provided with three selectable independent cavities, the input port of one cavity is set as a third input end, the input ports of the other two cavities are set as a first input end and a second input end, and the first input end, the second input end and the third input end are all exposed outside the body; the intracavitary section is provided with a left output end and a right output end which respectively correspond to the input end I and the input end II, the input end I and the left output end form a passage, the input end II and the right output end form another passage, and the left output end and the right output end respectively correspond to the positions of a left common carotid artery and a right common carotid artery in an operation; the third input end is used for guiding the supporting guide wire to be inserted into the cavity corresponding to the third input end so as to fix the main body pipe. The purpose of placing the brain protection umbrellas on the two sides at the same time is achieved, the use range of the sheathing canal is expanded, and operation efficiency is improved.

The present application relates to a vincamine derivative, a preparation method therefor, and use thereof, and belongs to the technical field of preparation of vincamine derivatives. The vincamine derivative has the following advantages: (i) Modification of the tail chain increases the lipid solubility of vincamine compounds without affecting the cerebral blood flow regulation of vincamine itself, thereby helping the carried drug penetrate the blood-brain barrier, exert a brain-protective effect, and improve cerebral microcirculatory disorders. (ii) The tertiary amine group in the parent nucleus structure of the vincamine derivative is ionizable under acidic conditions, which enables efficient delivery and lysosomal escape of nucleic acid drugs through charge adsorption, thereby improving intracellular transport. (iii) The vincamine derivative inherits various pharmacological activities inherent to vincamine, and has high safety. Therefore, the vincamine derivative has good application prospects in brain-targeted delivery of drugs for treating brain diseases.

This invention provides a composite composition containing nervonic acid and its use in brain nerve repair, belonging to the field of biotechnology. The invention uses nervonic acid and phosphatidylserine, combined with plant extracts fermented by a microbial concoction of *Lactobacillus acidophilus*: *Lactobacillus rhamnosus*: *Bacillus belyssae* = (2-3):1:1, to form a composite composition. This scientific formulation achieves synergistic effects from multiple components, improving neurological deficits, reducing cerebral infarction volume, decreasing the release of neurotrophic markers, and upregulating neurotrophic factor expression through multi-target synergistic effects. Furthermore, this synergistic effect depends on specific component ratios, providing crucial experimental support for the development of subsequent brain-protective functional compositions. This composition can be widely applied to the preparation of brain nerve repair drugs, functional foods, and dietary supplements, possessing promising industrialization prospects and clinical value.

The invention discloses an edible and medicinal composition with effects of lowering lipid and protecting heart and brain as well as a preparation method and application of the edible and medicinal composition, and belongs to the technical field of functional foods. The food and medicine homologous composition is prepared from three food and medicine homologous raw materials including broccoli seeds, lucid ganoderma and radix puerariae. Broccoli seeds are heated, dried and smashed, and broccoli seed powder is obtained; the preparation method comprises the following steps: uniformly mixing crushed lucid ganoderma, radix puerariae and broccoli seed powder according to a ratio, heating and extracting, concentrating the obtained filtrate, and carrying out spray drying to obtain a core composition; and adding the auxiliary active composition into the core composition, and uniformly mixing to obtain the edible and medicinal composition with the effects of lowering lipid and protecting heart and brain. The food and medicine homologous composition can be prepared into a multi-layer tablet with a core / shell structure, and the multi-layer tablet can be eaten as a functional food or health-care food with the functions of reducing blood fat, resisting oxidation or protecting heart and cerebral vessels. Animal experiments and crowd feeding trials show that the composition has the effect of regulating the overall metabolism of the body, can reduce the blood fat level and regulate intestinal flora, and has a good auxiliary relieving effect on symptoms of cardiovascular and cerebrovascular related diseases.

The application relates to the technical field of sports protective equipment, and discloses a buffering electronic head protector for taekwondo, which comprises a head protector main body, a buffering protection assembly and a sensing system, the head protector main body comprises a head protection part and a back brain protection part, an adjusting gap is formed in the bottom of the back brain protection part, adjusting belts are connected to the two sides of the adjusting gap, a drag tongue is arranged in the middle of the adjusting gap, the drag tongue is perpendicular to the length direction of the adjusting belt, the end of the drag tongue is integrally formed with the head protector main body, and the drag tongue is located on the side of the adjusting belt which faces the inside of the head protector main body. The application has the effect of improving the comfort of the wearer.

The invention relates to the technical field of medical instruments, in particular to a pediatric anesthesia brain protection constant-temperature infusion device based on low-temperature intervention and a using method.The pediatric anesthesia brain protection constant-temperature infusion device is characterized in that a limiting mechanism is arranged in a mounting box, a temperature increasing mechanism is arranged outside the middle of the mounting box, and a protection mechanism is arranged on one side of the temperature increasing mechanism; the medical infusion bottle hanging device has the beneficial effects that a screw rod and a screw sleeve are matched to drive a supporting rod and an opening box to move to a proper height, so that different medical workers are matched to hang infusion bottles, the infusion bottles of different specifications can be clamped, the medical workers can conveniently use the medical infusion bottle hanging device, and the overall hanging flexibility is improved; a transmission wheel and a belt are arranged to drive a two-way lead screw and a lead screw nut, so that a pipeline is rapidly clamped, temperature control is conveniently conducted through a second clamping plate and a heating piece which are externally connected with control equipment, meanwhile, the pipeline is conveniently limited through third clamping plates at the two ends, shaking caused by external force is prevented, and the overall stability is improved.

The application relates to the technical field of medical devices, in particular to a brain protection filter assembly, which comprises a first frame body and a second frame body connected with the first frame body, and an anchoring part is arranged on the second frame body and used for connecting and positioning when the brain protection filter assembly is recovered; in the application, the above-mentioned brain protection filter assembly is used, the covering positions of the first frame body and the second frame body are matched, foreign matters in the head-arm trunk artery, the left common carotid artery and the left subclavian artery can be filtered at the same time, the aortic arch is comprehensively covered, the anchoring part arranged on the second frame body is used for connecting and positioning when the brain protection filter assembly is recovered, the brain protection filter assembly can be freely recovered in the patient's body after operation, the foreign matter capturing time is prolonged, and the efficiency of preventing stroke is improved.

The invention provides a portable epigastric low-temperature brain protection treatment device which comprises a wearable unit, the wearable unit is configured to be capable of being worn on the abdomen, the wearable unit comprises liquid cooling pipes, the wearable unit is provided with a liver cooling area and a spleen cooling area, the liquid cooling pipes are distributed in the liver cooling area and the spleen cooling area, and the liquid cooling pipes are arranged in the liver cooling area and the spleen cooling area. The liver and the spleen are locally cooled; the first temperature sensor is arranged in the liver cooling area to detect the temperature of the skin of the area where the liver is located; the second temperature sensor is arranged in the spleen cooling area so as to detect the temperature of the skin of the area where the spleen is located; the refrigeration unit is connected with the liquid cooling pipe, the refrigeration unit is used for providing cooling liquid for the liquid cooling pipe and enabling the cooling liquid to circularly flow in the liquid cooling pipe, and the refrigeration unit can detect the temperature and adjust the refrigeration power, so that the liver and the spleen are cooled to the target temperature, and the liver and spleen inflammatory response after cerebral apoplexy is inhibited; therefore, the purpose of relieving brain injury is achieved.

The invention provides brain polypeptide raw materials capable of benefiting intelligence and strengthening brain, functional food and a preparation method of the brain polypeptide raw materials, and belongs to the technical field of functional food. The preparation method comprises the following steps: S1, pretreatment; s2, performing primary hydrolysis: adjusting the pH value of the pre-hydrolysate to 6.5-7.5, adding neutral protease with the addition amount being 3.5-4.5% of the mass of the bovine brain protein, performing enzymolysis at 50-60 DEG C for 1-3 hours, and performing enzyme deactivation to obtain first hydrolysate; s3, second hydrolysis: adjusting the pH value of the first hydrolysate to 6.0-7.0, adding papain with the addition amount being 1.0-3.0% of the mass of the bovine brain protein, carrying out enzymolysis at 45-65 DEG C for 1.5-2.5 h, and carrying out enzyme deactivation to obtain a second hydrolysate; and S4, performing post-treatment to obtain the brain polypeptide raw material powder. The brain polypeptide raw material can significantly remove DPPH free radicals and ABTS free radicals, inhibit the activity of acetylcholin esterase, repair PC12 nerve cells, inhibit the expression of a pro-apoptosis gene Bax and promote the expression of an anti-apoptosis gene Bcl-2, jointly exert the effects of benefiting intelligence, strengthening brain and protecting cranial nerves, and can be used as a functional factor to be applied to a functional product for benefiting intelligence and strengthening brain.

The invention relates to the technical field of low-temperature brain protection, in particular to a flexible low-temperature brain protection device capable of being flexibly cut, which comprises a flexible external heat conduction matrix layer and a head contact heat conduction layer in contact with the head, and a plurality of flexible semiconductor chilling plates are arranged between the external heat conduction matrix layer and the head contact heat conduction layer. The plurality of flexible semiconductor chilling plates are interconnected through interlaced conductive grids; a double-layer net-shaped interconnected conductive structure is arranged on the external heat-conducting substrate layer and is electrically connected with the flexible semiconductor chilling plate; a semiconductor chilling plate surface circuit is arranged on the head contact heat conduction layer and electrically connected with the flexible semiconductor chilling plate. The structure of the device is optimized, the device is convenient to use and flexible to adjust, the targeted cooling capacity is enhanced, the flexibility and precision of temperature control are improved, and the remarkable technical effect is achieved in the aspects of promoting development of the low-temperature brain protection treatment technology and the like.

The application discloses an integrated closed-loop brain protection device, and relates to the field of nerve interventional medical instruments. A balloon catheter comprises a balloon and a catheter body. A main cavity and multiple auxiliary cavities are arranged in the catheter body. The main cavity penetrates through the catheter body, and the balloon is arranged at the top end of the catheter body. A multi-interface Y valve comprises a main channel and multiple auxiliary channels. The main channel comprises a first channel and a second channel. One end of the first channel and one end of the second channel are in communication with each other. The end of the first channel is connected with the tail end of the catheter body. The auxiliary channels are installed on the side wall of the main channel and are in communication with each other. A filtering unit comprises a filter screen. One end of the filtering unit is connected with the auxiliary channels. A negative pressure auxiliary unit is connected with the other end of the filtering unit through a backflow pipe. The negative pressure auxiliary unit guides the flow direction of blood through negative pressure. The application aims to provide an integrated closed-loop brain protection device. Through the multi-cavity balloon guide catheter body and the multi-interface Y valve, the problems of microembolus escape causing ipsilateral stroke, multi-stage filtration and autologous blood transfusion are solved.

The invention relates to compositions comprising urolithins with active agents, particularly compositions comprising urolithins and agents which promote brain health and / or immune health. The invention also relates to such compositions, for use for the treatment or prevention of diseases, disorders and conditions, and for use in non-therapeutic treatments. Example of agents which promote brain health include brain protective agents (for example phosphatidylserine, phosphatidylcholine and / or choline), agents that enhance neurotransmission (for example a nootropic, for example ergothioneine, huperzine, aGPC, taurine and / or L-theanine), agents that promote neurogenesis (for example selenium); and brain essential nutrients (example Vitamin B6, B9, B12, magnesium salts, folic acid and / or L-methylfolate). Examples of agent which promote immune health include quercetin, Elderberry or an extract thereof; a selenium salt; and / or a zinc salt.

The application provides a vascular intervention catheter, an intravascular cooling system and a cooling method for brain protection, comprising a catheter seat, a tube body, an injection extension tube and a vacuum extension tube; one end of the tube body is connected with one end of the catheter seat, and the injection extension tube and the vacuum extension tube are arranged on the catheter seat; a main intervention tube, a cooling medium injection tube and a vacuum cavity are arranged in the tube body; the main intervention tube extends along the axial direction of the tube body, and the vacuum cavity is formed between the outer side wall of the main intervention tube and the inner side wall of the tube body; the vacuum cavity is connected with the vacuum extension tube in communication, and the injection extension tube is connected with the vacuum cavity in communication through the cooling medium injection tube. The application can be used for protecting the brain nerves of a stroke patient, and has the advantages of high cooling efficiency, simple operation, safety and reliability and the like.

The invention discloses an ice cap and a brain protection device, and relates to the technical field of medical instruments. The ice cap is used for the extracorporeal circulation operation and comprises an inner cap body and an outer cap body, the outer cap body is arranged on the inner cap body, a fluid filling cavity used for being filled with a cooling medium is defined by the outer cap body and the inner cap body, and the fluid filling cavity is suitable for being communicated with an external cooling machine. According to the ice cap, the fluid filling cavity is formed in the ice cap to contain the cooling medium, compared with a conventional manual ice water adding scheme, medical workers do not need to replace ice water when the ice cap is used, the using convenience of the ice cap is greatly improved, the cooling effect is improved, and therefore the brain protection effect is improved. In addition, the ice cap convenient to disassemble is provided, by arranging a zipper or a hook-and-loop fastener and the like, medical staff can conveniently open the ice cap and adjust the position of a monitoring device of the brain, operation is more convenient and faster, the monitoring device can be located at a proper examination position, and the medical monitoring accuracy is improved.

The invention provides a PEEP titration system and method based on multi-modal data, and belongs to the technical field of medical and industrial combination. According to the system, electroencephalogram signals, cerebral blood flow speed signals, arterial pressure signals and breathing machine PEEP level data in the mechanical ventilation process of a critical patient are synchronously collected, and after preprocessing and spectral analysis, the delta wave power proportion is calculated and serves as a sensitive index of cerebral hypoxia and ischemia; and aligning the multi-modal data according to timestamps and constructing a database. And based on a linear mixed effect model, performing statistical analysis by taking the DPR as a dependent variable and the PEEP level as an independent variable, and fitting a U-shaped curve to determine an optimal PEEP value. According to the PEEP titration system and method based on the multi-modal data, the blank that the influence of PEEP on a central nervous system cannot be objectively quantified in the prior art is filled up, cerebral ischemia and hypoxia injury is prevented from being aggravated by too high PEEP, and the respiration-brain protection collaborative management level of a neurological critical patient is remarkably improved.

The application discloses a tracheal catheter device with rotating permanent magnet positioning and selective brain cooling function and a temperature control method thereof, wherein a plurality of flexible semiconductor refrigerating sheets and a plurality of temperature and humidity sensors are inlaid on the inner wall side along the extension direction of the catheter and the side close to the outer wall of the flexible tracheal catheter; the function of heating the humidified gas entering the tracheal catheter is realized; the local low-temperature environment is realized by cooling the outer wall of the tracheal intubation tube, so that the brain is protected to a certain extent. The low temperature reduces the metabolic rate of brain cells and reduces the oxygen consumption of the brain, which helps to reduce brain injury and improve the brain function recovery effect of the patient; the flexible semiconductor refrigerating sheet and the temperature and humidity sensor are used for accurate temperature control, the temperature of the outer wall of the tracheal intubation tube is accurately adjusted, and the adverse effect of excessive temperature fluctuation on the brain protection effect is avoided, so that the method is more targeted and controllable than the traditional cooling method.

This invention provides a brain polypeptide raw material with brain-boosting and intelligence-enhancing properties and its preparation method. The preparation method includes the following steps: S1, pretreatment; S2, first hydrolysis: adjusting the pH of the pre-hydrolysate to 6.5-7.5, adding neutral protease at 3.5-4.5% of bovine brain protein mass, hydrolyzing at 50-60℃ for 1-3 hours, and obtaining the first hydrolysate after enzyme inactivation; S3, second hydrolysis: adjusting the pH of the first hydrolysate to 6.0-7.0, adding papain at 1.0-3.0% of bovine brain protein mass, hydrolyzing at 45-65℃ for 1.5-2.5 hours, and obtaining the second hydrolysate after enzyme inactivation; S4, post-treatment, to obtain the brain polypeptide raw material powder. This brain polypeptide raw material can significantly scavenge DPPH and ABTS free radicals, inhibit acetylcholinesterase activity, repair PC12 nerve cells, inhibit the expression of the pro-apoptotic gene Bax and promote the expression of the anti-apoptotic gene Bcl-2, thus exerting a brain-boosting and intelligence-enhancing effect and protecting brain nerves.