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147results about How to "Increase the strength of action" patented technology

Stone aggregate wrapped by microfine fibre polymer mortar thin layer and preparation method thereof

The invention discloses a stone aggregate wrapped by a microfine fibre polymer mortar thin layer and a preparation method thereof; the stone aggregate is formed by stone aggregate inner cores, an adhesive inner wrapping layer, a polymer cement mortar outer wrapping layer and an adhesive microfine fibre hair layer, wherein the adhesive inner wrapping layer and the stone aggregate are adhered firmly; microfine fibre filaments are anchored and rooted on the adhesive inner wrapping layer; and the polymer cement mortar outer wrapping layer and the adhesive inner wrapping layer are soluble mutually and can effectively form a whole body. Active powder in the polymer cement mortar outer wrapping layer contains silica fume, zeolite powder, finely-ground mineral slag, pulverized coal ash and the like, and can generate volcanic ash reaction with Ca(OH)2 crystal at the interface position of the set cement so as to generate gelled materials, and further carry out improved treatment on the weakest interfaces of set cement and the stone aggregate in concrete. The modified stone aggregate of the invention has good affinity with the set cement, and has higher binding power with the set cement.
Owner:NANTONG ZHONGRUN CONCRETE +1

Process for extracting general platycodoside and platycoligenin D from platycodon root, its medical application and its Chinese medicine

A process for extracting common platycodoside and platycodin D from platycodon root includes extracting in alcohol or water, depositing in alcohol for purifying it, purifying by macroreticular resin adsorbent column, drying to obtain common platycodoside, separating by chromatography, discriminating by thin silica gel layer, collecting the fractions with same Rf value, and volatilizing solvent to obtain platycodin D. They can be used for preventing and treating hyperglycemia and the complications caused by diabetes.
Owner:JILIN TIANYAO SCI & TECH

Double-metal hot jacket integrated automobile brake drum and machining method thereof

The invention provides a double-metal hot jacket integrated automobile brake drum, which consists of a drum-shaped shell and a tube-shaped casting liner, wherein the tube-shaped casting liner is arranged on the inner wall of the drum-shaped shell; the wall of the drum-shaped shell is made of constant-strength spinning steel. According to the double-metal hot jacket integrated automobile brake drum, a shell of the brake drum is made by a spinning technique of a spinning machine, the material of the brake drum shell is compact and has high strength, and the tube-shaped casting is taken as the liner so as to have the uniform thickness and simpleness and convenience in machining; a step of heating the shell of the brake drum specifically comprises the steps of bushing the tube-shaped casting liner into the shell under the condition of expansion of the diameter of the shell, condensing, fixedly fastening, and reinforcing the fixation between the shell of the brake drum and the casting liner by utilizing a pin; therefore the brake drum is ensured to have the advantages that the integrated strength is high, the material is utilized reasonably, the weight is light, the heat radiation performance is good, and the manufacturing technique process is suitable for automatic line operation.
Owner:泉州市泰智机械发展有限公司

Road repairing device

ActiveCN108842580AVibration crushingGuaranteed to be completely brokenRoads maintainenceElectric machineryRoad surface
The invention discloses a road repairing device, and belongs to the technical field of road repairing. The road repairing device comprises a vehicle body, a breaking and flat ramming mechanism, an asphalt filling mechanism and a compacting roller, wherein the breaking and flat ramming mechanism, the asphalt filling mechanism and the compacting roller are sequentially mounted on the vehicle body from the front end to the rear end in the marching direction of the vehicle body; the breaking and the flat ramming mechanism comprises a flat ramming gravity plate, and a drill bit which is fixed to the lower surface of the flat ramming gravity plate; the upper part of the flat ramming gravity plate is connected to a vibrating motor; a rotating shaft and a sector turntable which is fixed to one side of the rotating plate are arranged right above the vibrating motor; an arc-shaped hole is formed in the sector turntable; a moving rod which vertically passes through the arc-shaped hole is arrangedin the arc-shaped hole; a connecting rod is connected between the moving rod and the vibrating motor; two ends of the connecting rod are correspondingly hinged with the moving rod and the vibrating motor. According to the road repairing device, a broken and old pavement can be hammered and vibrated to realize combined breaking through one mechanism, and the broken pavement can be completely rammed, levelled and compacted; in addition, related acting strength is high; the breaking effect and the flat ramming effect are good.
Owner:ANHUI NORMAL UNIV

Desensitizing composite nano emulsion for sensitive skin repair and preparation method thereof

The invention relates to the technical field of medicaments and discloses desensitizing composite nano emulsion for sensitive skin repair. The emulsion is prepared from the following raw materials in preferable part by weight: 12.956 parts of isopropyl myristate, 29.4 parts of polyethylene glyceryl caprylate / caprate, 9.8 parts of polyglycerol-3-dioleate, 39.3475 parts of distilled water, 0.495 part of citric acid, 0.6525 part of sodium citrate, 0.005 part of metallothionein, 2.25 parts of daisy extract, 2.25 parts of oxymatrine, 1.246 parts of vitamin E, 0.79 part of chamomile, and 0.79 part of lavender oil. The average particle size of the emulsion is no more than 100 nm. The method greatly improves the skin penetration performance and dispersibility of active ingredients and the extensibility of the product on skin, thereby greatly improving the desensitizing effect of the product. The composite nano emulsion of the invention can be widely used for desensitizing sensitive skins.
Owner:董萍 +1

Production process for extra-large aperture super wall thickness square steel pipe

The invention relates to a production process for an extra-large aperture super wall thickness square steel pipe. A steel flat plate blank material with specified plate thickness and length and matched with the size of a final product is used, and bent through a bending machine, then the operation of rolling, closing, and overlap welding are performed on the blank materials, and the blank material is welded and reshaped through straightening, so that a final extra-large aperture super wall thickness square steel pipe is formed. The production process is not limited by parent metal, and production can be performed according to the requirements for sizes of different specifications of square steel pipes; Compared with other square steel pipe production process which needs hot working, the production process saves energy consumption, is simple, reduces procedures and improves production efficiency, so that the strength of the produced square steel pipe is improved to a great extent. The process technology fills a gap of the production of the domestic extra-large aperture super wall thickness square steel pipes, and has an important social significance.
Owner:常州钢劲型钢股份有限公司

Medicated diet for improving functions of spleen and stomach and enhancing immunoregulation capability and preparation method of medicated diet

The invention provides a medicated diet for improving functions of spleen and stomach and enhancing the immunoregulation capability and a preparation method of the medicated diet. The medicated diet comprises the following components: fructus jujubae, radix astragali preparata, ginseng, fried bighead atractylodes rhizome, poria cocos, fried semen coicis, agastache rugosus, radix paeoniae alba, fructus citrus sarcodactylis, fructus citri, Chinese yam, paederia scandens, caulis bambusae in taeniam, scorched medicated leaven, scorched malt, scorched hawthorn fruit, platycodon grandiflorum, radix aucklandiae, fructus aurantii, fructus amomi, pericarpium citri reticulatae, cassia twig, ginger, semen allii tuberose, radix saposhnikoviae, angelica sinensis, wolfberry fruit, rhizoma polygonati, lingzhi mushroom, rhodiola rosea, walnut meat, taraxacum, radix tinosporae, liquorice, brown granulated sugar and starch syrup. The medicated diet takes natural food materials, materials used as medicines and foods and materials used as health foods as the main raw materials, has the functions of invigorating spleen-stomach and replenishing qi, fortifying spleen and nourishing stomach, supporing Yang for consolidating superficies, reinforcing deficiency and strength, regulating qi function of human body, improving sub-health habitus and the like, can be used for improving functions of spleen and stomach and enhancing immunoregulation capability and has a good effect.
Owner:SHANXI UNIV

Welding method for high-nitrogen steel

The invention discloses a welding method for high-nitrogen steel. According to the method, a block amorphous alloy material serves as an interlayer during welding, connection is achieved through the superplasticity of the amorphous material in a supercooled liquid region, then the amorphous layer is diffused into a base material by increasing the temperature, and the welding of metallurgical bonding is achieved. The welding method is particularly suitable for welding among boards. A welded joint which is high in strength and good in forming can be obtained through the welding method, and when amorphous alloy powder of Fe75B15Si10Nb1 serves as an interlayer, the highest tensile strength of the welded joint is up to 780 MPa.
Owner:NANJING UNIV OF SCI & TECH +1

PLGA Gemcitabine sustained-release microsphere and its preparing method

A PLGA gemcitabine slow release microball is disclosed in the present invention belonging to pharmaceutical field. The PLGA gemcitabine slow release microball is prepared by supplementary polylactic acid-glycolic acid and raw material medicine gemcitabine with the weight ratio of 95 :5 to 35 :65. The present invention has the advantages that: preparing gemcitabine and polylactic acid-glycolic acid into slow release microball, directly sendint to tumor part by syringe to execute regional slow release chemotherapy, gemcitabine are released slowly, the tumor part has high medicine concentration, long duration, strong action intensity, big killing force to tumor cell, thereby can improve curative effect to tumor; medicine are centralized to act on local, whole body has little medicine amount, adverse response is minimal. After medicine are released, polylactic acid-glycolic acid start to degradate as lactic acid and glycolic acid, further degradate as carbon dioxide and water, no effect to human body.
Owner:CANCER INST & HOSPITAL CHINESE ACADEMY OF MEDICAL SCI +1

Water storage type recycled industrial waste residue plaza brick and preparation method thereof

The invention provides a water storage type recycled industrial waste residue plaza brick. The water storage type recycled industrial waste residue plaza brick is made by adopting a main material, a water reducer, a binding agent and running water, wherein the main material is prepared from the following raw materials in percentage by mass: 50-68% of desulphurizing gypsum, 20-30% of coal ash, 5-13% of silicon carbide residue, 2-7% of quick lime and 1-5% of cement. The invention also provides a method for preparing the water storage type recycled industrial waste residue plaza brick comprises the following steps: firstly preparing the main material; secondly, preparing blank; thirdly, carrying out compression moulding and maintenance, so that the water storage type industrial waste residue plaza brick is obtained. The water storage type recycled industrial waste residue plaza brick not only is high in strength but also can realize a water storing function, so that industrial waste residue is well utilized, influence of the industrial waste residue to the environment can be reduced, influence to running water on pavement is reduced, rainwater can be timely evaporated in sunny days, a surface water system is effectively restored, air quality is improved, and ecological cycle function of the pavement is improved.
Owner:XIAN UNIV OF SCI & TECH

In-situ casting construction method of reinforced concrete structural system using phosphogypsum as wall material

The invention discloses a cast-in-situ construction method for a reinforced concrete structural system taking phosphogypsum as a wall body material. When construction is performed on a reinforced concrete structural system building, the phosphogypsum is used as the wall body material, the reinforced concrete structural system and phosphogypsum wall bodies are cast in situ. When the reinforced concrete structural system and the phosphogypsum wall bodies are cast in situ, the reinforced concrete structural system is cast in four sections according to floor layers; the height of each section is controlled within 600 to 1,300 millimeters; the cast-in-situ construction is performed in layers and sections from the top to bottom; the reinforced concrete structural system is cast first at each section; and then the phosphogypsum wall body part is cast. The construction method has the advantages of easy construction, fast construction progress, good construction quality and low construction cost. In addition, the integrity and strength of buildings completed by the construction method are improved.
Owner:GUIZHOU UNIV +1

Chinese medicine preparation for treating senile dementia and preparation thereof

A Chinese medicine for treating senile dementia, dizziness, disturbed sleep, etc is prepared from fleece flower root, lotus leaf, cistanche, earthworm and uniflower swisscentaury root through respective extracting, and proportional mixing.
Owner:安徽雷允上药业有限公司

Berberine-based derivative and preparation method thereof, pharmaceutical composition, and antitumor uses of berberine-based derivative and pharmaceutical composition

The invention discloses a berberine-based derivative and a synthesis method thereof, and applications of the berberine-based derivative in preparation of products for prevention, alleviation and / or treatment of tumors, wherein the berberine-based derivative is a 12-aminotetrahydroberberine-based derivative represented by a general formula I or a physiologically acceptable salt thereof, a 12-N,N-disubstituted aminotetrahydroberberine-based derivative or a physiologically acceptable salt thereof, a 12-amino berberine quaternary ammonium salt derivative represented by a general formula II or a physiologically acceptable salt thereof, and a 12-N,N-disubstituted amino baterine quaternary ammonium salt derivative or a physiologically acceptable salt thereof. According to the present invention, the solubility of the berberine-based derivative is significantly improved compared to the raw material chlorinated berberine quaternary ammonium salt compound; and the obtained berberine-based derivative can provide inhibition activity on the growth of tumor cell lines, and can be used for preparing products for prevention, alleviation and / or treatment of tumors, wherein the action intensity of the berberine-based derivative is significantly higher than the berberine quaternary ammonium salt raw material, or is comparable to the positive control drug, or is higher than the positive control. The general formulas I and II are defined in the specification.
Owner:INST OF MATERIA MEDICA AN INST OF THE CHINESE ACAD OF MEDICAL SCI

New use of methyl liensinine

The invention discloses a new use of methyl liensinine. Methyl liensinine respectively regulates M8 and V1 subtype transient receptor potential ion channels (TRPM8 and TRPV1 for short) of mammal including human, so as to prepare medicine for treating related diseases joined by the ion channels (such as cold hyperalgesia, parkinsonism, nociceptive bladder syndrome, chronic obstructive lung diseaseand tumours of skin, prostate, breast, lung and colon). The action strength of methyl liensinine of the invention is higher than that of menthol.
Owner:INST OF CHINESE MATERIA MEDICA CHINA ACAD OF CHINESE MEDICAL SCI

Composite nanoemulsion used for epidermis repair and preparation method thereof

The invention relates to the technical fields of the biomedicine and the skin health-care and facial cosmetics, in particular to a composite nanoemulsion used for epidermis repair and a preparation method thereof. The product prepared in the invention can quicken the injured epidermis repair and the epidermis barrier function repair, can improve the stability of protein polypeptide drugs or efficacy compositions and enhance the dissolvability of the difficultly dissolved matter and the stability of the easily hydrolyzed matter by promoting the skin to permeate and absorb the efficacy compositions of the epidermis, can scientifically and reasonably match natural drugs, antioxidants and biological derived skin repair polypeptide, and can exert the better epidermis repair efficiency and speed by combining the high-efficiency skin delivery carrier blank nanoemulsion system. Moreover, the product prepared in the invention can also improve the nutrition and moisturizing capabilities of the skin greatly, create an appropriate micro-ecological environment for the epidermis repair and enhance the synergism of the efficacy compositions. In addition, the product prepared in the invention can not contain the preservative and the essence, lowers the toxicity, improves the safety and can be industrially produced without adopting special equipment and energy.
Owner:董萍 +1

Technology for producing spheroidal graphite cast iron

The invention discloses a technology for producing spheroidal graphite cast iron, which is characterized in that by optimizing a casting mold technology, a proper filtering cast system is employed, a reasonable chemical component is selected, spheroidising and inoculating treatment can be controlled, high-quality ductile iron pig iron is selected, and the qualified castings of the spheroidal graphite cast iron with -40 DEG C low-temperature impact can be produced by a graphite pretreatment technology and the filtering cast technology. The technology comprises the steps of selecting the raw auxiliary materials of pig iron, waste steel, an inoculants and a nodulizer, melting in an electric furnace, spheroidising, tapping and inoculating, performing stream inoculation, pretreating graphite, filtering and casting, casting test block, performing shot blast cleaning, processing test block, performing a low-temperature impact tensile test, and performing UT, MT and RT flaw detection. The technology is suitable for producing the spheroidal graphite cast iron with -40 DEG C low-temperature impact.
Owner:杨长国

Instant plant composition for sobering up and preparing method thereof

A sobering-up composition in the form of instant powder is prepared from 6 Chinese-medicinal materials including pueraria root, bitter pattra fruit, tuckahoe, schisandra fruit, green tea and cloves through proportional mixing, breaking, pulverizing, adding excipient and suspending agent, granulating, and baking. Its advantage is high effect.
Owner:武汉东保科技开发有限责任公司

Polyoxometalate cluster organic amine salt and preparation method thereof

The invention discloses polyoxometalate cluster organic amine salt and a preparation method thereof, belonging to the field of chemical technology of inorganic polyoxometalate clusters. A molecular formula of the polyoxometalate cluster organic amine salt is (Q)Mxm12O40. The preparation method comprises the following steps: dropwise adding an organic amine salt solution into a polyoxometalate cluster solution, reacting for a period of time, centrifuging, washing, drying, and re-crystallizing to obtain the polyoxometalate cluster organic amine salt. The preparation method is easy and convenient to operate; all raw materials are obtained from the market and are low in cost. According to the prepared novel polyoxometalate cluster organic amine salt, organic amine positive ions with certain spatial structures are introduced, the types of acting forces between negative ions and positive ions are enriched, the acting intensity of the negative and positive ions is increased, the application range of a polyoxometalate cluster catalyst is conveniently expanded, and the application prospects are wide.
Owner:BEIJING INSTITUTE OF TECHNOLOGYGY

Standardized processing technology of Chinese herbal piece stewed aconite

The invention discloses a standardized processing technology of a Chinese herbal piece stewed aconite. The standardized processing technology is characterized by comprising the following steps of: soaking salted aconite, taking out and draining water when soaking water is 25 DEG C and electrical conductivity is lowered to below 6000mu s / cm; uniformly and flatly spreading salted aconite with expanded part up in clean and burnt fine bran ash with thickness of 10cm-40cm, spreading a plurality of layers of clean ginger slices over the bran ash, and flatly covering 1-5 pieces of coarse paper on the ginger slices, spreading a layer of fine clean bran ash with thickness of 3cm-10cm on the coarse paper, and flatly spreading dry bran hulls with thickness of 5cm-30cm on the ash; igniting the dry bran hulls at four corners, controlling the upper-end temperature of the aconite to 110-180 DEG C, controlling the lower-end temperature of the aconite to 70-130 DEG C, continuously baking for 36-72 hours, taking out the aconite when the bran ash is cooled, placing in a heating container, continuously steaming for 6-12 hours, pouring out, spreading and airing to the room temperature, slicing, and drying at 60 DEG C-80 DEG C until the moisture content is 5%-13%, thus obtaining the Chinese herbal piece stewed aconite. The standardized processing technology has obvious advantages of reducing toxicity, enhancing efficacy and reducing active ingredient loss in comparison with a normal steaming method and a cooking method, so that the stewed aconite pieces are high-quality.
Owner:江西中医药高等专科学校

Compound vinegar-egg juice with functions of reducing high blood fat, high blood pressure and high blood sugar and preparation method thereof

InactiveCN108552491AIt has the function of reducing three high symptomsPromote recoveryNervous disorderAntipyreticPolygonum fagopyrumCordyceps
The invention discloses compound vinegar-egg juice with the functions of reducing high blood fat, high blood pressure and high blood sugar. The compound vinegar-egg juice is prepared by processing rawmaterials comprising the following components: functional components, fruits, eggs, vinegar, probiotics and a dairy product, wherein the functional components comprise tartary buckwheat, pilose asiabell roots, largehead atractylodes rhizome, tuckahoe, honey-fried licorice roots, astragalus roots, red sage roots, mulberries, longans, Chinese wolfberries, fiveleaf gynostemma herb, lotus leaves, kudzu roots, solomonseal rhizome, sharpleaf galangal fruits, jujubes and cordyceps sinensis. The compound vinegar-egg juice product has good effects, relatively ideal functions of reducing high blood fat, high blood pressure and high blood sugar, good mouthfeel and high nutrient content.
Owner:内蒙古延龄堂医药科技有限公司

Polysiphonia urceolata bromophenol compound as well as preparation method and application thereof

The invention relates to the technical field of food additives, in particular to a bromphenol compound in polysiphonia urceolata and the preparation method and purpose. The invention is characterizedin that the bromphenol compound capable of eliminating the activity of free radical can be obtained from the polysiphonia urceolata of oceanic red alga by the method of extraction and separation, theconstitutional formula (I) or (II) is shown, wherein the R1 is H, Br, OH, OCH3 or OCH2CH3; the R2 is H, Br, OH, OCH3 or OCH2CH3; the R3is H, Br, OH, OCH3 or OCH2CH3, the preparation method is characterized in that the polysiphonia urceolata is washed by seawater; the gravels and miscellaneous algae on the surface of the polysiphonia urceolata are removed, and then the leaching, solvent distribution and repeated chromatographic separation are implemented after the polysiphonia urceolata is dried in the shade and crushed, so that a monomer compound is obtained, wherein the R1 is H, Br, OH, OCH3or OCH2CH3; the R2 is H, Br, OH, OCH3 or OCH2CH3; the R3is H, Br, OH, OCH3 or OCH2CH3. The bromphenol compound which is obtained by the preparation method of the invention has the advantages that: thebromphenol compound can be used as the food additives to delay or prevent the oxidation and metamorphosis of edible oil or oil-retaining food because of the inducement of the free radical.
Owner:INST OF OCEANOLOGY - CHINESE ACAD OF SCI

High-toughness high temperature resistant cable material

The invention relates to the technical field of wire and cable materials, in particular to a high-toughness high temperature resistant cable material which comprises the following components: an ethylene-propylene-diene monomer, polyethylene resin, vulcanizing silicone rubber, white carbon black, a heat-resistant filler, a toughened fiber, a composite flame retardant, a silane coupling agent, a lubricating dispersant and a Ca-Zn composite stabilizer, wherein the heat-resistant filler comprises the following components: calcined kaolin, nanometer aluminum oxide, N-phenylmaleimide and dibutyltindilaurate; and the lubricating disperse is a mixture of glyceryl tristearate and ethylene bis oleamide according to equal mass ratio. The toughed fiber is a special ceramic fiber subjected to surfaceroughening and dendronization. Through the use of the toughed fiber, the toughness, the high temperature resistance and the ageing resistance of the cable material are greatly improved.
Owner:HEFEI DAHU ELECTRIC WIRE & CABLE TECH CO LTD

Jade vein simulated high-intensity low-shrinkage amino moulding plastic particle material and production method

InactiveCN105017718AImprove performanceHandlingpowder-freeOXALIC ACID DIHYDRATEPolymer science
The invention discloses a jade vein simulated high-intensity low-shrinkage amino moulding plastic particle material and a production method. The high-intensity low-shrinkage amino moulding plastic particle material is characterized by being prepared from formaldehyde water solution, urea, melamine, auxiliary agents, sodium hudroxide, filling materials and the like, wherein the filling materials are mixed bodies of wood powder, inorganic and organic medium short fiber, paper pulp plates, waste paper wood pulp, grain and fruit hulls, bone meal, starch and inorganic oxides; the auxiliary agents are urotropine, oxalic acid, water, ammonium sulfamate, magnesium oxide, zinc oxide, ammonium chloride, ethanol, trolamine, ammonia water, PPG, T-8, sodium-naphthalenesulfonate, glycerin, magnesium carbonate, hydroxyphenol, pigment, zinc stearate and the like. The production method of the jade vein simulated high-intensity low-shrinkage amino moulding plastic particle material comprises the following steps that in a resin synthesis stage, a general alkali-acid-alkali method is selected for synthesizing the resin; in an evaporation polycondensation stage, the resin and the filling materials are input into a vacuum granulation reaction kettle, and the sealed production is completed in one step.
Owner:陈天云

Sea weed bromophenol compound as well as preparation method and application thereof

InactiveCN101177382AEasy to prepareDelay or prevent oxidative deteriorationOrganic chemistryOrganic compound preparationFood additiveEdible oil
The invention relates to the technical field of food additives, in particular to an algae bromophenol compound and the preparation method and purpose. The invention is characterized in that the algae bromophenol compound which is capable of deactivating radials is obtained through the extraction and separation from oceanic red algae symphyocladia latiuscula, and the constitutional formula is shown in Figure (I), wherein the R1 is OH, OCH3 or Br; R2 is OH, OCH3 or Br; R3 is H, CH3 or Ac; R1 or R2 is Br. The algae bromophenol compound from the invention has obvious function on removing DPPH free radical activity for deactivating radials, which can be used as a food addition agent to delay or prevent the oxidation and metamorphosis of edible oil or oil-retaining food caused by the inducement of free radical.
Owner:INST OF OCEANOLOGY - CHINESE ACAD OF SCI

Application of organic dicarboxylic acid salts in preparing medicaments for preventing and treating cataract

The invention aims to provide application of organic dicarboxylic acid salts, namely new application in pharmacy, in particular application in preparing medicaments for preventing and treating cataract. New anti-cataract active components in No.1, No.2, No.3, No.4, No.6, NO.7, No.8 and No.9 compounds are discovered by screening rabbit and rat H2O2 induced cataract and rat xylose induced cataract models, and the medical application of the compounds in preparing the medicaments for resisting oxidative damage and sugar metabolism disorder induced cataract is discovered. The No.4 compound has strong and high effect of resisting phacoscotasmus, and has good medicinal prospect. The No.4 compound has obvious effects of improving rabbit lens water-soluble proteins (sol-pro) and total antioxidant capacity (T-AOC), and reducing malondialdehyde (MDA), so the effect of the No.4 compound of resisting H2O2 induced lens oxidative damage is related to the strong oxidation resistance of the No.4 compound.
Owner:ZHEJIANG SHAPUAISI PHARMA

Medicine for treating hypertension and its preparing process

Owner:重庆茂霖农业生物技术有限公司

Geopolymer and preparation method thereof

The invention discloses a preparation method of a geopolymer. The method comprises the following steps: mixing fly ash, alkaline residue and water, and feeding an obtained mixture into a wet ball mill; adding a grinding aid into the wet ball mill for grinding to obtain slurry A; feeding zeolite powder and water into the wet ball mill for wet grinding to obtain slurry B; mixing the slurry A and theslurry B to obtain mixed slurry C; and adding sodium hydroxide and water glass into the slurry C to obtain the fly ash geopolymer solid-liquid mixed slurry. The hazard problems caused by chloride ions in alkaline residue in conventional technology is solved, the use amount of strong base is reduced, the frosting phenomenon is reduced, the performance of the water reducing agent is not influenced,and the working performance is adjustable; the prepared concrete finished product is superior to the geopolymer prepared by the traditional process in the aspects of strength, durability and the like.
Owner:HUBEI UNIV OF TECH

Recombinant lamprey lysin as well as preparation method and application thereof in preparing antithrombotic medicament

The invention discloses a recombinant lamprey lysin protein as well as a preparation method and application thereof in preparing an antithrombotic medicament. The recombinant lamprey lysin protein is a product which is obtained through the following steps: constructing a lamprey protein lysin gene on a pET28a (+) vector; and carrying out efficient induction expression on the gene in Escherichia coli. The lamprey lysin cDNA (complementary deoxyribonucleic acid) sequence 351bp is long, and the protein consists of 117 amino acids, can perform specific binding with glycoprotein GpIIb / IIIa on a blood platelet cell membrane, competitively antagonizes the binding of fibrinogen and blood platelets, prevents the activation of the blood platelets and variation of GpIIb / IIIa receptor conformation and blocks the binding of the receptor and various ligand, so as to inhibit the final common passageway for blood platelet aggregation so as to block thrombosis. The recombinant lamprey lysin has an obvious antithrombotic effect.
Owner:LIAONING NORMAL UNIVERSITY

Coptisine derivatives, as well as preparation method, medicinal composition and anti-tumor application thereof

The invention discloses coptisine derivatives, a synthesis method thereof, and application of the coptisine derivatives to preparation of products for preventing, relieving and / or treating tumor products. The coptisine derivatives are an 8-iminodihydrogen coptisine derivative and a N-dihydrogen coptisine-8-imino derivative which are as shown in a general formula I as well as an 8-N,N-disubstituted amino coptisine quaternary ammonium salt derivative and an 8-N,N-disubstituted amino-13-substituted coptisine quaternary ammonium salt derivative which are as shown in a general formula II. The coptisine derivatives have inhibitory activity on the growth of tumor cell strains, and the effect intensity of the coptisine derivatives is obviously higher than that of coptisine quaternary ammonium salt raw materials or equal to that of a positive control medicine or higher than that of a positive control medicine; part of the compounds does not show remarkable cytotoxicity on IEC-6 enterocyte; the coptisine derivatives can be applied to preparation of the products for preventing, relieving and / or treating tumor.
Owner:INST OF MATERIA MEDICA AN INST OF THE CHINESE ACAD OF MEDICAL SCI
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