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3 results about "Metallothionein" patented technology

Metallothionein (MT) is a family of cysteine-rich, low molecular weight (MW ranging from 500 to 14000 Da) proteins. They are localized to the membrane of the Golgi apparatus. MTs have the capacity to bind both physiological (such as zinc, copper, selenium) and xenobiotic (such as cadmium, mercury, silver, arsenic) heavy metals through the thiol group of its cysteine residues, which represent nearly 30% of its constituent amino acid residues.

Giant salamander polypeptide powder composition formula for immunoregulation

The invention belongs to the field of polypeptide powder, and particularly relates to a giant salamander polypeptide powder composition formula for immunoregulation, which comprises 10-20 parts of giant salamander polypeptide powder, 30-40 parts of oyster polypeptide, 15-25 parts of soybean polypeptide, 5-15 parts of Chinese yam powder, 6-14 parts of apple powder, 4-16 parts of Chinese wolfberry fruit powder, 5-14 parts of sea buckthorn fruit powder, 22-36 parts of fructo-oligosaccharide, 5-13 parts of water-soluble dietary fiber and 1-8 parts of stevioside. The giant salamander polypeptide small molecule peptide in the composition is high in proportion, and the giant salamander polypeptide composition contains metallothionein (MT) and has the effects of expelling toxins by heavy metals and delaying senescence. The giant salamander protein and amino acid composition proportion is basically consistent with human beings, and can be easily absorbed by human bodies. The components of arginine, glutamine, leucine and the like can effectively enhance the immune function of a patient and reduce the occurrence rate of postoperative infection. In addition, the composition also contains DHA and phosphatidylserine, and is especially suitable for people who need to quickly recover physique after an operation, people with cardiovascular and cerebrovascular diseases and people with low immunity in a high-pressure working environment.
Owner:WUXI JIHAI HEALTH BIOTECHNOLOGY CO LTD

Agents containing malonic acid or derivatives thereof for restoring metal homeostasis

The present invention relates to malonic acid and its derivatives according to the following formula (I) for use as an agent for promoting metallothionein biosynthesis in a patient: # imgabs0 # wherein X and Y are each independently selected from the group consisting of O-M +,-OR1 and-NR2R3 wherein M + is selected from the group consisting of a monovalent or multivalent metal cation,-OR1 is selected from the group consisting of a monovalent or multivalent metal cation, and-R2R3 is selected from the group consisting of a monovalent or multivalent metal cation. And R1, R2 and R3 are each independently selected from hydrogen and a saturated or unsaturated, linear, branched or cyclic hydrocarbyl group having 1 to 25 carbon atoms wherein one or more carbon atoms are optionally substituted by O or N, and wherein R2 and R3 are optionally bonded to each other and form a heterocyclic hydrocarbyl group together with a nitrogen atom. The invention also relates to pharmaceutical compositions containing the compounds of formula (I).
Owner:OXFORD ANTIBIOTICS (PHARM) GRP CO LTD

Agent for restoring metal homeostasis

The disclosure relates to malonic acid and derivatives thereof of formula (I) below for use as an agent for promoting metallothionein biosynthesis in a patient:X and Y are each independently selected from —O−M+, —OR1, and —NR2R3, M+ is selected from monovalent or polyvalent metal cations, and R1, R2 and R3 are each independently selected from hydrogen and saturated or unsaturated, linear, branched or cyclic hydrocarbon radicals having from 1 to 25 carbon atoms, and one or more carbon atoms are optionally substituted for O or N, R2 and R3 being optionally connected to form a heterocyclic hydrocarbon radical together with the nitrogen atom. The disclosure also relates to a pharmaceutical composition containing a compound of formula (I).
Owner:OXFORD ANTIBIOTIC GRP GMBH