363results about How to "Improve energy transfer" patented technology

Guided ablation instruments are disclosed for creating lesions in tissue, especially cardiac tissue for treatment of arrhythmias, including atrial fibrillation. In one aspect of the invention, a percutaneous catheter is disclosed with an endoscope positionable in the instrument's distal end region to obtain an image. The image allows the clinician to determine whether contact has been achieved (or blood has been cleared from an ablative energy transmission path) before ablation begins or while ablation is occurring. In one embodiment, percutaneous ablation catheters are disclosed having at least one central lumen and one or more balloon structures at the distal end region of the instrument. Also disposed in the distal end region are an illuminating light source and an endoscope capable of collecting sufficient light to relay an image to the user. The instruments can further include an ablation element. The ablation element can be a contact ablation element, or a radiant energy emitter, which is preferably independently positionable within the lumen of the instrument and adapted to project ablative energy through a transmissive region of the instrument body (and/or balloon) to a target tissue site proximate to the pulmonary veins. The energy can delivered without the need for contact between the energy emitter and the target tissue so long as a clear transmission pathway is established. The endoscope element of the instrument allows the clinician to determine the position of the instrument and, if radiant energy is to be employed, see if such a pathway is clear. Moreover, because the position of the radiant energy emitter can be varied, endoscopic guidance permits the clinician to select a desired location and dose for the lesion.

This invention relates to oligonucleotides comprising a molecular switch which may exist in an “open” or “closed” position. The molecular switch portion of the probe is particularly sensitive to the identity of sequences complementary to the molecular switch. Oligonucleotides containing a molecular switch are applicable to all kinds of hybridization processes. Due to the sensitivity of the switch domain of the oligonucleotide, probes containing a molecular switch are particularly useful in the identification of single point mismatches. More specifically, a portion, but not all, of the oligonucleotide becomes unbound from a mismatched target. The invention further relates to methods of using said oligonucleotides for research reagents, and clinical diagnostics. An exemplary oligonucleotide comprises a first hybridizable domain, a second bridging block domain, and a third binding domain.

A method and apparatus of providing endovascular therapy. The steps include arranging optical fibers within a catheter, the catheter having a tip whose length is at least 1 cm and whose diameter of less than 1 millimeter, connecting an excimer laser to the optical fibers; and delivering laser energy from the excimer laser in excess of 60 fluence at 40 Hertz through the optical fibers. The delivering of the laser energy may be to non-calcified or calcified deposits of an atherosclerotic lesion to ablate the same. The method also includes the step of inserting the catheter through an artery by pushing the same until the tip is in within laser energy striking distance of the atherosclerotic lesion.

A stable shock absorbing prosthetic foot that transfers energy between heel strike and toe-off. A toe plate is separated from one or more other plates by a bumper assembly located at each of the toe end and heel end of the foot. Certain embodiments of the shock absorbing foot of the present invention are designed for use with a prosthetic ankle. A torsion adapter may also be used to attach a prosthetic foot of the present invention to the remainder of a prosthesis.

A method for delivering ultrasound energy to a patient's intracranial space includes forming at least one aperture in the patient's skull, introducing at least one acoustically conductive medium into the intracranial space to contact brain tissue of the patient, advancing an ultrasound device at least partially through the aperture in the skull, and transmitting ultrasound energy to the intracranial space, using the ultrasound device. In some embodiments, the acoustically conductive medium may be cooled to help regulate the temperature of the patient's brain tissue.

Apparatus is provided for ablating tissue of a patient by applying ultrasound energy to the tissue. The apparatus is typically delivered to the targeted tissue via a catheter and includes an ultrasound array, which is adapted to be driven as a phased array to concentrate the ultrasound energy on the targeted tissue while avoiding surrounding tissue.

Methods and instruments are disclosed for creating lesions in tissue, especially cardiac tissue, for treatment of arrhythmias and the like, by employing an elastic balloon and an energy emitter, which is independently positionable within the lumen of the instrument and adapted to project a series of spots of ablative energy through a transmissive region of the balloon to a target tissue site. The energy emitter preferably is configured such the spots of energy result in a series of lesions formed in the target tissue region when the emitter is activated, the lesions having an average area ranging from about 5 mm² to about 100 mm². In one aspect of the invention, percutaneous ablation instruments are disclosed in the form of catheter bodies having one or more balloon structures at the distal end region of the instrument and an energy emitting element, which is independently positionable and rotatable within a lumen of the instrument and adapted to project ablative energy through a transmissive region of the balloon to a target tissue site in contact with, or proximal to, the balloon surface.

Photoacoustic measurement system are configured with a special view towards efficient coupling of optical and acoustic energy between respective transducers and a tissue test site. In particular, a disposable substrate provides support for advanced optical paths including, for example, windows, lenses, and index matching gels or fluids. In addition, substrates may also accommodate arrays of coupling sites corresponding to a plurality of acoustic detectors spatially separated. These substrates may additionally include means to affix and secure the device to a measurement head having optoelectronic and electromechanical transducers therein. Further, these substrates include mechanisms which help to affix the substrates to test sites in stabile and secure fashion.

The present invention relates to an apparatus for carrying out a plasma chemical vapor deposition process by which one or more layers of doped or undoped silica can be deposited on the interior of an elongated glass substrate tube. The present invention further relates to a method for manufacturing an optical fiber using such an apparatus.

An ocean wave power plant provided for by respective interconnected functional units comprising a support structure (1a, 1b) is disclosed. The support structure (1a, 1b) is terminated in a lower end with a fastening bracket (9c) which can be anchored in a single point to a mass (9e) when deployed in the sea. A submergible uplift floating body (2) is providing buoyancy for the ocean wave power plant when deployed in the sea. The a uplift floating body (2) is attached to the support structure (1a, 1b), an electric power generating subsystem (A) supported by a platform (8) is terminating the support structure (1a, 1b) in an upper end of the support structure. A transmission member (4, 4a, 18) is attached in one end to a floating body (3) and in another end to the power generating subsystem (A) transferring wave motion from the floating body (3) to the power generating subsystem (A).

The present invention relates to comprehensive systems, devices and methods for delivering energy to tissue for a wide variety of applications, including medical procedures (e.g., tissue ablation, resection, cautery, vascular thrombosis, treatment of cardiac arrhythmias and dysrhythmias, electrosurgery, tissue harvest, etc.). In certain embodiments, systems, devices, and methods are provided for treating a tissue region (e.g., a tumor) through application of energy.

A golf club head having an insert mechanically coupled to a frame. The construction allows a golf club head to be fabricated with a combination of dissimilar materials, resulting in a club head with improved performance. In some embodiments, the insert comprises an outer insert material, an inner insert material, and a sandwiched material. The sandwiched material may be constructed with a plurality of voids having a varying distribution, thereby resembling a biological structure. Methods for forming a golf club having an insert mechanically coupled to a frame are also disclosed.

The invention discloses a bulletproof composite board comprising an buffer layer as the external layer, an absorption layer connected with the buffer layer, and a barrier layer connected with the absorption layer, wherein the buffer layer comprises a plurality of disks superposed into a scalelike structure, and the disks are provided with a convex surface towards the external layer; the absorption layer comprises weftless fabric pressure layers and knitted fabrics, which are superposed, and the weftless fabric pressure layers and the knitted fabrics comprise fibers of which the strength is atleast 15 cN/dtex and the modulus is at least 390 cN/dtex; and the barrier layer comprises a metal plate of which the tensile strength is greater than 1000 MPa. A bullet is deflected under the action of the convex surface of the disks, and the penetrating capability of the bullet is reduced; under the alternate actions of the weftless fabrics and the knitted fabrics, the energy of the bullet is quickly transferred and absorbed; and finally, the bullet is effectively prevented when getting into contact with the barrier layer with high strength.

The ablation systems, ablation probes, and corresponding methods according to the present disclosure reduce or eliminate energy radiating from an ablation probe into the environment. Some ablation probes include a retractable sheath that shields at least the radiating portion of the ablation probe. The retractable sheath and/or the ablation probe may include conduits through which a fluid may flow to shield the radiating portion and to drive the retractable sheath to an extended state. Other ablation probes include apertures defined in the probe walls through which the fluid can flow to expand a balloon surrounding the radiating portion. Yet other ablation probes include a thermal indicator to indicate the temperature of the ablation probe to a user. The ablation systems include fluid circuits and associated mechanical controls for varying the contents and/or flow rate of the fluid provided to the radiating portion of the ablation probe.

The invention relates to a pneumatic spring percussion mechanism comprising a driving piston moving back and forth in a housing of the percussion mechanism and a percussion piston, wherein a pneumatic spring is configured between the driving piston and the percussion piston. The movement of the driving piston can be transmitted to a percussion piston by means of said pneumatic spring. The driving piston can be driven by an electric linear motor and is connected to an aromatic of the linear motor, forming a single piece therewith. This arrangement makes it possible to eliminate the use of a conventional rotary motor and a crank mechanism to drive the driving piston.

The invention discloses a method for explosion and leakage increase of a low permeability sandstone uranium deposit, which includes steps as follows: A. blast holes are drilled through the overburden, the top rock of occurrence terrane to the proper position of the occurrence terrane from surface. An underreamer is used to locally ream the blast holes at the occurrence terrane to meet charging requirement; B. blasting cartridges are arranged in the blast holes in an uncoupling way; the detonator is waterproof; uncoupling charge for explosion comprises radial uncoupling charge and axial uncoupling charge; C. after the blasting cartridges are arranged properly, hole seal measures shall be taken to build up the blast holes; D. the blasting cartridges are initiated through short delay blasting which comprises short delay blasting inside the blast holes and short delay blasting between the blast holes. The recovery factor and the yield per unit of in-situ Uranium leaching are improved; the uranium deposit resource of low permeability sandstone type is used completely, thus alleviating the shortages of uranium resources.