A formulation and method for preventing and treating HPV infection of the cervix in women

Abstract

The application belongs to the technical field of disease prevention and treatment, and particularly relates to a formula and a method for preventing and treating HPV infection of female cervical, which specifically comprises 18-22g of Calophyllum inophyllum, 8-12g of Phellodendron, 13-17g of honeysuckle, 8-12g of Sophora, 13-17g of Spermacoce latifolia, 8-12g of Curcuma, 13-17g of Smilax, 13-17g of Cnidium, 13-17g of Isatidis Folium, 8-12g of Sophora, 3-7g of Meligetta, 5-7g of wild chrysanthemum, 2-4g of menthol, 3-5g of sodium hyaluronate, 1-3g of egg yolk globulin powder and distilled water. The formula can effectively prevent and treat HPV infection of female cervical. The formula has the effects of sterilization, removal of corruption, promotion of mycotic regeneration and repair, healing of cervical micro-wounds, and prevention of HPV infection of the body through cervical micro-wounds.

Description

Technical Field

[0001] This invention relates to the field of disease prevention and treatment technology, specifically to a formula and method for preventing and treating HPV infection of the cervix in women. Background Technology

[0002] HPV—human papillomavirus infection—is one of the main culprits behind women's health problems. It is a sexually transmitted disease and a major biological factor contributing to cervical cancer. Although cervical cancer results from the long-term synergistic effect of multiple carcinogenic factors, human papillomavirus (HPV) is closely related to its development. When HPV is positive, the type must first be determined. If high-risk types such as HPV16 and 18 are positive, the harm to women can include cervical lesions. For women planning to become pregnant, it can also easily lead to intrauterine infection of the fetus, resulting in neonatal laryngeal tumors.

[0003] Treatment for low-grade cervical intraepithelial neoplasia (LSIL) and high-grade cervical intraepithelial neoplasia (HSIL) complicated by HPV infection is crucial. Cervical HPV infection causes significant psychological and physiological trauma to female patients. Although the advent of HPV vaccines promises to gradually reduce and eliminate human papillomavirus infection in the future, various factors such as vaccine quantity, price, type, safety, efficacy, and adverse reactions exist. Price is a major obstacle to HPV vaccination. In recent years, there have been many drugs on the market for treating HPV infection, but some are expensive and have low patient acceptance.

[0004] Therefore, a formula and method for preventing HPV infection of the female cervix are proposed to address the aforementioned problems. Summary of the Invention

[0005] The purpose of this invention is to provide a formula and method for preventing and treating HPV infection of the female cervix, so as to solve the problems mentioned in the background art.

[0006] To achieve the above objectives, the present invention provides the following technical solution: a formula for preventing and treating HPV infection of the female cervix, the formula specifically comprising: 18-22g of Brucea javanica, 8-12g of Phellodendron chinense, 13-17g of Lonicera japonica, 8-12g of Sophora flavescens, 13-17g of Hedyotis diffusa, 8-12g of Curcuma zedoaria, 13-17g of Smilax glabra, 13-17g of Cnidium monnieri, 13-17g of Isatis indigotica, 8-12g of Sophora flavescens, 3-7g of Vespa nidus, 5-7g of Chrysanthemum indicum, 2-4g of Menthol, 3-5g of Sodium hyaluronate, 1-3g of egg yolk globulin powder, and distilled water.

[0007] Preferably, the formula specifically includes: 18g of Brucea javanica, 8g of Phellodendron chinense, 13g of Lonicera japonica, 8g of Sophora flavescens, 13g of Hedyotis diffusa, 8g of Curcuma zedoaria, 13g of Smilax glabra, 13g of Cnidium monnieri, 13g of Isatis indigotica, 8g of Sophora flavescens, 3g of Vespa nidus, 5g of Chrysanthemum indicum, 2g of Menthol, 3g of Sodium hyaluronate, 1g of egg yolk globulin powder, and distilled water.

[0008] Preferably, the formula specifically includes: 20g of Brucea javanica, 10g of Phellodendron chinense, 15g of Lonicera japonica, 10g of Sophora flavescens, 15g of Hedyotis diffusa, 10g of Curcuma zedoaria, 15g of Smilax glabra, 15g of Cnidium monnieri, 15g of Isatis indigotica, 10g of Sophora flavescens, 5g of Vespa nidus, 6g of Chrysanthemum indicum, 3g of Menthol, 4g of Sodium hyaluronate, 2g of egg yolk globulin powder, and distilled water.

[0009] Preferably, the formula specifically includes: 22g of Brucea javanica, 12g of Phellodendron chinense, 17g of Lonicera japonica, 12g of Sophora flavescens, 17g of Hedyotis diffusa, 12g of Curcuma zedoaria, 17g of Smilax glabra, 17g of Cnidium monnieri, 17g of Isatis indigotica, 12g of Sophora flavescens, 7g of Vespa nidus, 7g of Chrysanthemum indicum, 4g of Menthol, 5g of Sodium hyaluronate, 3g of egg yolk globulin powder, and distilled water.

[0010] Preferably, the specific processing method of this formula is as follows:

[0011] Step 1: Select the following herbs by weight: Brucea javanica, Phellodendron chinense, Lonicera japonica, Sophora flavescens, Hedyotis diffusa, Curcuma zedoaria, Smilax glabra, Cnidium monnieri, Isatis indigotica, Sophora flavescens, Vespa nidus, and Chrysanthemum indicum. Wash them in clean water and then air dry them at 20-25 degrees Celsius. After drying, prepare a cooking container and place the herbal mixture inside. Add 10-12 times the amount of distilled water and heat it over high heat at 120-140 degrees Celsius for 2-3 hours. Then adjust the temperature to 70-80 degrees Celsius and continue heating for 40-50 minutes. After cooling, use a filter to filter out the herbal residue inside.

[0012] Step 2: Add menthol, sodium hyaluronate and egg yolk globulin powder to the cooled solution, stir and mix for 1-2 minutes to obtain the drug.

[0013] A method for preventing HPV infection of the female cervix, as described above, includes the following specific steps:

[0014] Step 1: First, the patient needs to empty her bladder and lie flat on the gynecological examination bed with her legs apart to expose her genitals and perineum. A sterile speculum is used to open the vagina and fully expose the cervix.

[0015] Step 2: Use a sterile cotton ball soaked in 1% povidone-iodine solution to repeatedly wipe the cervix, wiping in concentric circles clockwise from the squamocolumnar junction of the external cervical os towards the vaginal fornix for 5-7 minutes. Then, insert a gauze soaked in 1% povidone-iodine solution into the vagina and remove it after 4-6 hours, leaving a gauze tail at the vaginal opening for easy removal by the patient.

[0016] Step 3: On the second day, the patient lies on the gynecological examination bed in the same position, and the cervix is ​​exposed in the same way. The prepared reagent is used to thoroughly rinse the surface of the cervix with a disposable irrigator. After removing the speculum, the vagina is irrigated again. After the irrigation process is completed, the patient needs to remain in the lithotomy position for 15-20 minutes to allow the irrigation solution to fully penetrate the cervix. The above method is repeated twice a week, with six treatments constituting one course. Two courses constitute one treatment cycle. Treatment is not performed during menstruation. Treatment is stopped for one month after two courses, and HPV and cervical TBS tests are repeated 3-7 days after menstruation ends.

[0017] Compared with the prior art, the beneficial effects of the present invention are:

[0018] The formula mentioned in this application can effectively prevent and treat HPV infection of the cervix in women. During treatment, after applying undiluted povidone-iodine solution to the cervix and inserting povidone-iodine gauze into the vagina and removing it, a white membranous substance can be seen peeling off the surface of the cervical and vaginal mucosa before the next day's irrigation with the traditional Chinese medicine mixture. After the vagina is thoroughly irrigated with the traditional Chinese medicine mixture, the solution is fully absorbed, and a thin layer of light yellow traditional Chinese medicine film can be seen evenly covering the cervical and vaginal mucosa. The patient reported that after removing the traditional Chinese medicine gauze, several sheet-like membranous substances were discharged from the vagina. Upon returning to the hospital, a gynecological examination revealed a "map-like" white membranous substance attached to the cervix, which easily detached after wiping, and the exposed cervical mucosa was watermelon red. During the treatment interval, the patient returned to the hospital for another application of undiluted povidone-iodine solution to the cervix. The cervical and vaginal mucosa were pink, and the mucosa showed increased elasticity compared to before treatment. After several treatments, the secretions gradually decreased, becoming clear and transparent, or changing from purulent and light yellow to a small amount of white. In some patients, the cervix even showed varying degrees of erosion (micro-wounds). After treatment, the cervix became smooth. This is considered to be the bactericidal, debridement, and tissue regeneration effects of this formula, which promotes the healing of cervical micro-wounds and further prevents cervical HPV from infecting the body through cervical micro-wounds. Detailed Implementation

[0019] This invention provides a technical solution:

[0020] A formula for preventing and treating HPV infection of the cervix in women, specifically comprising: 18-22g of Brucea javanica, 8-12g of Phellodendron chinense, 13-17g of Lonicera japonica, 8-12g of Sophora flavescens, 13-17g of Hedyotis diffusa, 8-12g of Curcuma zedoaria, 13-17g of Smilax glabra, 13-17g of Cnidium monnieri, 13-17g of Isatis indigotica, 8-12g of Sophora flavescens, 3-7g of Vespa nidus, 5-7g of Chrysanthemum indicum, 2-4g of Menthol, 3-5g of Sodium hyaluronate, 1-3g of egg yolk globulin powder, and distilled water.

[0021] The medicinal power of *Brucea javanica* is the strongest in the formula, and its dosage is slightly larger; *Phellodendron chinense* and *Lonicera japonica* are slightly less potent, both being cold in nature and possessing the effects of clearing heat and drying dampness, killing parasites and detoxifying, antiviral, and antitumor properties. The three herbs follow the principles of "mutual reinforcement" and "mutual compatibility."

[0022] Both Sophora flavescens and Hedyotis diffusa are cold in nature and have the effects of clearing heat and drying dampness, killing parasites, promoting diuresis, anti-inflammatory and anti-tumor effects. When used externally, they have significant effects in relieving itching, killing bacteria and fighting tumors. They can enhance the effect of the principal drug in treating HPV infection and treat concurrent symptoms in addition to the main disease. For example, Sophora flavescens has a therapeutic effect on eczema, leukorrhea, itchy skin caused by wet sores, and vaginitis; Hedyotis diffusa has a good therapeutic effect on gynecological inflammations such as adnexitis, pelvic inflammatory disease and urinary tract infection.

[0023] Smilax glabra: It is sweet, bland, and neutral in nature, and has the effects of promoting diuresis and removing dampness, strengthening the spleen and replenishing the middle jiao; it can enhance the detoxification and dampness removal functions of the principal herb and be used for urinary tract infections and leukorrhea;

[0024] Isatis leaf: It is cold in nature and has the effects of detoxifying, cooling blood, clearing heat and promoting diuresis. It has a certain effect on improving immunity, so it can enhance the immune function of vaginal mucosa after treatment of cervical HPV infection.

[0025] Sophora flavescens is also used as an adjuvant herb; its anti-inflammatory and anti-allergic effects can alleviate the toxicity and potency of the principal herb and prevent allergic reactions on the skin and mucous membranes when applied externally. This is the principle of "mutual restraint" in traditional Chinese medicine compatibility.

[0026] Curcuma zedoaria: It is warm in nature and has a pungent and bitter taste. It has the effects of breaking up qi and promoting blood circulation, eliminating stagnation and relieving pain. It can break up blood stasis, remove necrotic tissue and promote tissue regeneration. It can inhibit a variety of pathogenic bacteria and has obvious anti-inflammatory effects. It not only has a direct tumor-killing effect, but can also induce or promote the body's immune rejection response to tumors, thus having an anti-tumor effect.

[0027] Cnidium monnieri: It has a pungent, bitter and warm nature. It is used to treat eczema and allergies. It has the effects of removing dampness, relieving itching, relieving pain and killing parasites. It has a good effect on vulvitis and vaginitis in women.

[0028] Exposed bee honeycomb is neutral in nature and slightly toxic. Its effects include dispelling wind and relieving pain, attacking toxins and reducing swelling, killing parasites and relieving itching. It has inhibitory effects on both acute and chronic inflammation and also enhances immunity. It is used for purulent infections and is particularly effective on purulent wounds, having the effects of removing necrotic tissue, reducing inflammation, and promoting tissue regeneration. It can be used for external washing and application.

[0029] The specific ingredients of this formula are: 18g of Brucea javanica, 8g of Phellodendron chinense, 13g of Lonicera japonica, 8g of Sophora flavescens, 13g of Hedyotis diffusa, 8g of Curcuma zedoaria, 13g of Smilax glabra, 13g of Cnidium monnieri, 13g of Isatis indigotica, 8g of Sophora flavescens, 3g of Vespa nidus, 5g of Chrysanthemum indicum, 2g of Menthol, 3g of Sodium hyaluronate, 1g of egg yolk globulin powder, and distilled water.

[0030] The specific ingredients of this formula are: 20g of Brucea javanica, 10g of Phellodendron chinense, 15g of Lonicera japonica, 10g of Sophora flavescens, 15g of Hedyotis diffusa, 10g of Curcuma zedoaria, 15g of Smilax glabra, 15g of Cnidium monnieri, 15g of Isatis indigotica, 10g of Sophora flavescens, 5g of Vespa nidus, 6g of Chrysanthemum indicum, 3g of Menthol, 4g of Sodium hyaluronate, 2g of egg yolk globulin powder, and distilled water.

[0031] The specific ingredients of this formula are: 22g of Brucea javanica, 12g of Phellodendron chinense, 17g of Lonicera japonica, 12g of Sophora flavescens, 17g of Hedyotis diffusa, 12g of Curcuma zedoaria, 17g of Smilax glabra, 17g of Cnidium monnieri, 17g of Isatis indigotica, 12g of Sophora flavescens, 7g of Vespa nidus, 7g of Chrysanthemum indicum, 4g of Menthol, 5g of Sodium hyaluronate, 3g of egg yolk globulin powder, and distilled water.

[0032] The specific processing method for this formula is as follows:

[0033] Step 1: Select the following herbs by weight: Brucea javanica, Phellodendron chinense, Lonicera japonica, Sophora flavescens, Hedyotis diffusa, Curcuma zedoaria, Smilax glabra, Cnidium monnieri, Isatis indigotica, Sophora flavescens, Vespa nidus, and Chrysanthemum indicum. Wash them in clean water and then air dry them at 20-25 degrees Celsius. After drying, prepare a cooking container and place the herbal mixture inside. Add 10-12 times the amount of distilled water and heat it over high heat at 120-140 degrees Celsius for 2-3 hours. Then adjust the temperature to 70-80 degrees Celsius and continue heating for 40-50 minutes. After cooling, use a filter to filter out the herbal residue inside.

[0034] Step 2: Add menthol, sodium hyaluronate and egg yolk globulin powder to the cooled solution, stir and mix for 1-2 minutes to obtain the drug.

[0035] A method for preventing HPV infection of the cervix in women, the specific steps of which are as follows:

[0036] Step 1: First, the patient needs to empty her bladder and lie flat on the gynecological examination bed with her legs apart to expose her genitals and perineum. A sterile speculum is used to open the vagina and fully expose the cervix.

[0037] Step 2: Use a sterile cotton ball soaked in 1% povidone-iodine solution to repeatedly wipe the cervix, wiping in concentric circles clockwise from the squamocolumnar junction of the external cervical os towards the vaginal fornix for 5-7 minutes. Then, insert a gauze soaked in 1% povidone-iodine solution into the vagina and remove it after 4-6 hours, leaving a gauze tail at the vaginal opening for easy removal by the patient.

[0038] Step 3: On the second day, the patient lies on the gynecological examination bed in the same position, and the cervix is ​​exposed in the same way. The prepared reagent is used to thoroughly rinse the surface of the cervix with a disposable irrigator. After removing the speculum, the vagina is irrigated again. After the irrigation process is completed, the patient needs to remain in the lithotomy position for 15-20 minutes to allow the irrigation solution to fully penetrate the cervix. The above method is repeated twice a week, with six treatments constituting one course. Two courses constitute one treatment cycle. Treatment is not performed during menstruation. Treatment is stopped for one month after two courses, and HPV and cervical TBS tests are repeated 3-7 days after menstruation ends.

[0039] This study demonstrated significant efficacy in treating female patients with cervical cervical infections caused by a single high-risk or mixed high-risk HPV type, particularly high-risk HPV types 16, 18, 52, 53, and 33. To date, 68 patients have completed the treatment course. Of these, 50 were cured, 6 showed significant improvement, 7 showed improvement, and 5 showed no improvement.

[0040] (1) Among the 50 cured patients, the high-risk HPV types included were: HPV16, HPV18, HPV51, HPV52, HPV53, HPV56, HPV59, HPV31, HPV33, HPV39, and HPV66.

[0041] (2) The six patients with significant improvement had mixed HPV infections, namely HPV51 and 53; HPV16 and 52; HPV33 and 81; HPV18 and 33; HPV31 and 82; and HPV16 and 31. After treatment, all mixed infections showed significant improvement, with one type of HPV cured in each case, namely HPV53, HPV16, HPV33, HPV18, HPV31, and HPV16.

[0042] (3) Seven effective patients were infected with a single high-risk HPV type or a mixture of high-risk HPV types. The cases were: HPV18 and 33 infection; HPV52 infection; HPV31 infection; HPV51; HPV66; HPV31 and HPV68; and HPV56. All seven patients underwent HPV-DNA titer testing before treatment. Although they did not turn negative after treatment, the HPV titer decreased several times after retesting.

[0043] (4) To date, the cure rate of this treatment study is 73.53%, the significant efficacy rate is 82.35%, the effective rate is 92.65%, and the ineffective rate is 7.35%.

[0044] Example 1:

[0045] The specific processing method for this formula is as follows:

[0046] Step 1: Select the following herbs by weight: Brucea javanica, Phellodendron chinense, Lonicera japonica, Sophora flavescens, Hedyotis diffusa, Curcuma zedoaria, Smilax glabra, Cnidium monnieri, Isatis indigotica, Sophora flavescens, Vespa nidus, and Chrysanthemum indicum. Wash them in clean water and then place them in an environment of 20 degrees Celsius to dry the surface moisture. After drying, prepare a cooking container and place the mixture of Chinese herbs in it. Add 10 times the amount of distilled water and control the temperature at 120 degrees Celsius to heat it for 2 hours. Then adjust the temperature to 70 degrees Celsius and continue heating for 40 minutes. After cooling, use a filter to filter out the Chinese herbal residue inside.

[0047] Step 2: Add menthol, sodium hyaluronate and egg yolk globulin powder to the cooled solution, stir and mix for 1 minute to obtain the drug;

[0048] Example 2:

[0049] The specific processing method for this formula is as follows:

[0050] Step 1: Select the following herbs by weight: Brucea javanica, Phellodendron chinense, Lonicera japonica, Sophora flavescens, Hedyotis diffusa, Curcuma zedoaria, Smilax glabra, Cnidium monnieri, Isatis indigotica, Sophora flavescens, Vespa nidus, and Chrysanthemum indicum. Wash them in clean water and then air dry them at 22.5 degrees Celsius. After drying, prepare a cooking container and place the herbal mixture inside. Add 11 times the amount of distilled water and heat it at 130 degrees Celsius for 2.5 hours. Then adjust the temperature to 75 degrees Celsius and continue heating for 45 minutes. After cooling, use a filter to filter out the herbal residue inside.

[0051] Step 2: Add menthol, sodium hyaluronate and egg yolk globulin powder to the cooled solution, stir and mix for 1.5 minutes to obtain the drug;

[0052] Example 3:

[0053] The specific processing method for this formula is as follows:

[0054] Step 1: Select the following herbs by weight: Brucea javanica, Phellodendron chinense, Lonicera japonica, Sophora flavescens, Hedyotis diffusa, Curcuma zedoaria, Smilax glabra, Cnidium monnieri, Isatis indigotica, Sophora flavescens, Vespa nidus, and Chrysanthemum indicum. Wash them in clean water and then place them in an environment of 25 degrees Celsius to dry the surface moisture. After drying, prepare a cooking container and place the mixture of Chinese herbs in it. Add 12 times the amount of distilled water and control the temperature at 140 degrees Celsius to heat it for 3 hours. Then adjust the temperature to 80 degrees Celsius and continue heating for 50 minutes. After cooling, use a filter to filter out the Chinese herbal residue inside.

[0055] Step 2: Add menthol, sodium hyaluronate and egg yolk globulin powder to the cooled solution, stir and mix for 2 minutes to obtain the drug.

[0056] The foregoing has shown and described the basic principles, main features, and advantages of the present invention. It will be apparent to those skilled in the art that the present invention is not limited to the details of the above exemplary embodiments, and that the present invention can be implemented in other specific forms without departing from the spirit or basic characteristics of the present invention. Therefore, the embodiments should be regarded as exemplary and non-limiting in all respects. The scope of the present invention is defined by the appended claims rather than the foregoing description, and therefore all changes falling within the meaning and scope of the equivalents of the claims are intended to be included within the present invention.

[0057] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A formula for preventing HPV infection of the female cervix, characterized in that, The specific ingredients of this formula are: 18-22g of Brucea javanica, 8-12g of Phellodendron chinense, 13-17g of Lonicera japonica, 8-12g of Sophora flavescens, 13-17g of Hedyotis diffusa, 8-12g of Curcuma zedoaria, 13-17g of Smilax glabra, 13-17g of Cnidium monnieri, 13-17g of Isatis indigotica, 8-12g of Sophora flavescens, 3-7g of Vespa nidus, 5-7g of Chrysanthemum indicum, 2-4g of Menthol, 3-5g of Sodium hyaluronate, 1-3g of egg yolk globulin powder, and distilled water.

2. The formula for preventing HPV infection of the female cervix according to claim 1, characterized in that: The specific ingredients of this formula are: 18g of Brucea javanica, 8g of Phellodendron chinense, 13g of Lonicera japonica, 8g of Sophora flavescens, 13g of Hedyotis diffusa, 8g of Curcuma zedoaria, 13g of Smilax glabra, 13g of Cnidium monnieri, 13g of Isatis indigotica, 8g of Sophora flavescens, 3g of Vespa nidus, 5g of Chrysanthemum indicum, 2g of Menthol, 3g of Sodium hyaluronate, 1g of egg yolk globulin powder, and distilled water.

3. The formula for preventing HPV infection of the female cervix according to claim 1, characterized in that: The specific ingredients of this formula are: 20g of Brucea javanica, 10g of Phellodendron chinense, 15g of Lonicera japonica, 10g of Sophora flavescens, 15g of Hedyotis diffusa, 10g of Curcuma zedoaria, 15g of Smilax glabra, 15g of Cnidium monnieri, 15g of Isatis indigotica, 10g of Sophora flavescens, 5g of Vespa nidus, 6g of Chrysanthemum indicum, 3g of Menthol, 4g of Sodium hyaluronate, 2g of egg yolk globulin powder, and distilled water.

4. The formula for preventing HPV infection of the female cervix according to claim 1, characterized in that: The specific ingredients of this formula are: 22g of Brucea javanica, 12g of Phellodendron chinense, 17g of Lonicera japonica, 12g of Sophora flavescens, 17g of Hedyotis diffusa, 12g of Curcuma zedoaria, 17g of Smilax glabra, 17g of Cnidium monnieri, 17g of Isatis indigotica, 12g of Sophora flavescens, 7g of Vespa nidus, 7g of Chrysanthemum indicum, 4g of Menthol, 5g of Sodium hyaluronate, 3g of egg yolk globulin powder, and distilled water.

5. The formula for preventing HPV infection of the female cervix according to claim 1, characterized in that: The specific processing method for this formula is as follows: Step 1: Select the following herbs by weight: Brucea javanica, Phellodendron chinense, Lonicera japonica, Sophora flavescens, Hedyotis diffusa, Curcuma zedoaria, Smilax glabra, Cnidium monnieri, Isatis indigotica, Sophora flavescens, Vespa nidus, and Chrysanthemum indicum. Wash them in clean water and then air dry them at 20-25 degrees Celsius. After drying, prepare a cooking container and place the herbal mixture inside. Add 10-12 times the amount of distilled water and heat it over high heat at 120-140 degrees Celsius for 2-3 hours. Then adjust the temperature to 70-80 degrees Celsius and continue heating for 40-50 minutes. After cooling, use a filter to filter out the herbal residue inside. Step 2: Add menthol, sodium hyaluronate and egg yolk globulin powder to the cooled solution, stir and mix for 1-2 minutes to obtain the drug.

6. A method for preventing HPV infection of the female cervix as described in any one of claims 1-5, characterized in that: The specific steps for preventing HPV infection of the cervix in women are as follows: Step 1: First, the patient needs to empty her bladder and lie flat on the gynecological examination bed with her legs apart to expose her genitals and perineum. A sterile speculum is used to open the vagina and fully expose the cervix. Step 2: Use a sterile cotton ball soaked in 1% povidone-iodine solution to repeatedly wipe the cervix, wiping in concentric circles clockwise from the squamocolumnar junction of the external cervical os towards the vaginal fornix for 5-7 minutes. Then, insert a gauze soaked in 1% povidone-iodine solution into the vagina and remove it after 4-6 hours, leaving a gauze tail at the vaginal opening for easy removal by the patient. Step 3: On the second day, the patient lies on the gynecological examination bed in the same position, and the cervix is ​​exposed in the same way. The prepared reagent is used to thoroughly rinse the surface of the cervix with a disposable irrigator. After removing the speculum, the vagina is irrigated again. After the irrigation process is completed, the patient needs to remain in the lithotomy position for 15-20 minutes to allow the irrigation solution to fully penetrate the cervix. The above method is repeated twice a week, with six treatments constituting one course. Two courses constitute one treatment cycle. Treatment is not performed during menstruation. Treatment is stopped for one month after two courses, and HPV and cervical TBS tests are repeated 3-7 days after menstruation ends.