The invention discloses an air compressor with pipeline air tightness detection. The air compressor comprises a box body, wherein the lower surface of the box body is fixedly connected with a bottom column, the front surface of the box body is hinged with a box door, the lower surface in the box body is fixedly connected with a damping assembly, the damping assembly is fixedly connected with a fixing frame, an air storage tank is fixedly connected with the fixing frame, the upper surface of the air storage tank is fixedly connected with an output pipe, the output pipe penetrates through the box body longitudinally, the other end of the output pipe is fixedly connected with a pipeline, the top end of the pipeline is fixedly connected with an air tightness detection assembly, the top end, corresponding to one side of the output pipe, of the air storage tank is fixedly connected with an air compressor, the output end of the air compressor is connected with the air storage tank through anair pipe, the input end of the air compressor is fixedly connected with an air inlet device through the air pipe, and openings are formed in the lower end of one side of the box body and the upper endof the other side of the box body. The air compressor has the function of detecting air tightness of the pipeline, has a good heat dissipation effect, and has a better shock absorption effect, and afilter screen is convenient to disassemble, clean and replace.