The invention discloses a cold-chain logistics box based on the Internet of Things, relates to the technical field of cold-chain logistics, and mainly aims at solving the problems that an existing cold-chain logistics box is poor in cold air fluidity and influences the refrigeration effect. The logistics box comprises a box body, a box cover and a refrigerating unit, the box cover is detachably installed on the top of the box body, a containing plate used for containing objects is installed on the lower portion of an inner cavity of the box body, a plurality of through holes are evenly formedin the containing plate, the refrigerating unit comprises a cooling box, a motor, a driving bevel gear, a driven bevel gear, a rotating shaft, blowing fan blades and suction fan blades, and logisticsbox further comprises a protection unit. The protection unit comprises a first connecting rod, a sliding block, a first magnet, a second magnet, a third magnet and a second connecting rod, the refrigeration unit is mounted, continuous circulation of cold air is formed, and therefore the better effect is achieved. The protection unit is arranged, multi-stage buffer protection can be conducted, theprotection effect is good, the cooling box can be conveniently taken out to replace ice bags, and convenience and practicability are achieved.