An intelligent ultrasonic conductance directional drug penetration therapeutic device

Abstract

This invention provides an intelligent ultrasonic conductance directional drug penetration therapeutic device. Compared to existing technologies, this invention also includes a drug penetration module that contacts the patient's skin to apply the drug to the patient's skin, an adaptation module that adjusts the drug penetration efficiency of the drug penetration module according to the patient's skin location, and a fixation module for adapting the drug penetration module to different skin locations. This invention integrates ultrasonic treatment, drug delivery, infrared sensing, and compress clamping functions, achieving a combined application of multiple treatment methods. Utilizing ultrasonic technology, it allows drugs to penetrate the patient's skin more easily, thereby improving drug utilization.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to an intelligent ultrasonic conductance directional drug penetration therapeutic device. Background Art

[0002] Ultrasonic drug penetration therapy is a new transdermal drug delivery technology using an intelligent ultrasonic conductivity directional drug penetration device. It is fundamentally different from various physical therapy methods. It utilizes the effects of ultrasonic radiation, through specific biophysical methods and means, and through the cavitation effect of ultrasound to increase the permeability of tissues to drugs. In addition, the kinetic energy of ultrasound enables drugs to penetrate into the diseased tissues and organs in the human body through the skin or mucous membranes, forming local concentration and infiltration within a certain range, and promoting the transport of drugs from extracellular to intracellular, thereby achieving drug efficacy and toxicity reduction, directly exerting the therapeutic effect of drugs, and achieving the purpose of target treatment.

[0003] This experimental team has been browsing and studying a large amount of relevant records and data for the relevant technologies of drug-permeable therapeutic instruments for a long time. At the same time, relying on relevant resources and conducting a large number of relevant experiments, after a large number of searches, it was found that there are existing technologies such as CN104491980B, CN102989080B, CN104491980B, and CN102512753B disclosed in the prior art. For example, the transdermal drug delivery electromagnetic introduction instrument disclosed in the prior art includes a signal transmitter, an energy controller, a power amplifier, electrodes, and a medicine storage box. The output of the signal transmitter is connected to the input of the energy controller, the output of the energy controller is connected to the input of the power amplifier, the output of the power amplifier is connected to the electrodes, the electrodes are embedded in the medicine storage box, the medicine is stored in the medicine storage box, and the medicine storage box with electrodes is placed on the skin surface. The purpose of this instrument is to promote the percutaneous penetration of drugs.

[0004] The present invention is made to solve the common problems in the art, such as the difference in drug absorption between different skin locations in drug permeation therapy, which makes it difficult to ensure the consistency of the dosage and effect of drug permeation therapy. Summary of the Invention

[0005] The purpose of the present invention is to address the deficiencies in the current field and to propose an intelligent ultrasonic conductance directional drug penetration therapeutic device.

[0006] In order to overcome the deficiencies of the prior art, the present invention adopts the following technical solutions:

[0007] An intelligent ultrasonic conductance directional drug penetration therapeutic device includes a drug penetration module for applying a drug to the patient's skin by contacting the patient's skin, an adaptation module for controlling the penetration efficiency of the drug penetration module according to different skin positions of the patient, and a fixing module for fixing the drug penetration module to different skin positions of the patient.

[0008] The penetration efficiency includes the ultrasonic frequency of the ultrasonic transmitter, the amount of the medicine, and the operation time of the ultrasonic transmitter. The medicine penetration module includes an empty shell, a compress, an ultrasonic conductivity unit arranged in the empty shell, a clamping unit arranged outside the empty shell for automatically clamping and fixing the compress, a medicine delivery unit arranged in the empty shell for outputting the medicine to the compress, a matching plate attached to one end of the empty shell, and a heating unit arranged in the matching plate.

[0009] The heating unit includes a plurality of inner channels respectively arranged inside the matching plate, and heating strips respectively arranged in each inner channel. The hollow shell includes a shell opening arranged in the middle area of ​​the shell wall at one end and having an open structure, and three chambers arranged inside the hollow shell and separated from each other by baffles.

[0010] The three chambers are identified as the first chamber, the second chamber, and the third chamber in sequence, wherein the second chamber is located between the first chamber and the third chamber, and the shell opening passes through and connects to the second chamber, wherein the opening edge of the shell opening is provided with a snap-fit ​​groove, and the side wall of the mating plate is provided with a snap-fitting groove that is snap-fitted and fixed with the snap-fitting groove, and the mating plate is fixed to the shell opening by snapping and fixing the snap-fitting groove with the snap-fitting groove, and the outer wall of the shell on the side where the shell opening is located is used as the working wall.

[0011] Furthermore, the ultrasonic conductivity unit includes an ultrasonic transmitter that generates ultrasonic waves of a specific frequency, a controller that controls the switch, frequency and power of the ultrasonic transmitter, and a sensor for monitoring the intensity and frequency of the ultrasonic waves to ensure that they remain within a safe and effective range. The ultrasonic transmitter is arranged in the second chamber, and the ultrasonic transmitter abuts against the matching plate, and the matching plate abuts against the patient's skin.

[0012] Furthermore, the adaptation module includes an input interface that allows the user to manually input the skin position that the drug permeation module is to contact, a database that stores the ultrasonic frequencies of the ultrasonic conductivity unit corresponding to the skin of different parts of the human body, an information extraction unit that further retrieves the corresponding ultrasonic frequency from the database according to the skin position received from the input interface, and an instruction sending unit that generates a control instruction based on the data of the information extraction unit and sends it to the control device to control the ultrasonic transmitter to generate the corresponding frequency.

[0013] Furthermore, the hollow shell further comprises two linear grooves symmetrically arranged on the working wall, two limiting grooves symmetrically arranged on the working wall, a first through-outlet arranged on the working wall for connecting the first chamber with the outside of the hollow shell, and a second through-outlet arranged on the working wall for connecting the third chamber with the outside of the hollow shell.

[0014] The linear groove and the limiting groove are arranged perpendicular to each other, and two ends of the limiting groove extend to be connected with the two linear grooves respectively.

[0015] Furthermore, the clamping unit includes an infrared sensor embedded in the working wall, and two clamping mechanisms symmetrically arranged on the working wall for clamping and fixing the compress on the empty shell.

[0016] The infrared sensor is used to monitor whether a compress is present on the working wall, and when a compress is present, the medicine delivery unit is allowed to perform a medicine delivery operation.

[0017] Furthermore, the medicine delivery unit includes a medicine tank stored in the first chamber, a medicine outlet arranged on the medicine tank, a connecting port arranged on the working wall and connected to the first chamber, a liquid outlet nozzle arranged through the connecting port, a transmission pipe connected to the medicine outlet at one end and connected to the medicine outlet nozzle at the other end, and a one-way valve arranged in the transmission pipe, and a liquid pump for quantitatively driving the medicine in the medicine tank to be transferred from the transmission pipe to the medicine outlet.

[0018] The beneficial effects achieved by the present invention are:

[0019] 1. The present invention combines ultrasonic technology with specific agents to increase the skin permeability of drugs, thereby improving the therapeutic effect. At the same time, the intensity and frequency of ultrasonic waves can be monitored in real time through the sensor in the ultrasonic conductivity unit to ensure that they are always within a safe and effective range. The adaptation module provides an input interface, allowing the user to manually select the contact position of the drug permeation module, providing a more intuitive and convenient use experience. Since the adaptation module is implemented through the application of the terminal device and connected to the drug permeation module through communication technology, it provides patients with greater mobility and portability. The present invention provides a drug permeation therapeutic device that integrates safety, efficiency, portability and intelligence, which can provide patients with a more efficient and personalized treatment experience.

[0020] 2. The present invention integrates ultrasonic treatment, drug delivery, infrared sensing and compress clamping functions, realizing the combined application of multiple treatment methods. Ultrasonic technology is used to make it easier for drugs to penetrate the patient's skin, thereby improving drug utilization. The infrared sensor can intelligently detect whether a compress has been applied to the patient, ensuring that the drug delivery operation is not started until a compress is present, thereby improving safety. Integrating multiple treatment and detection functions into one device can save medical resources and costs, and provide an efficient, safe and personalized treatment experience.

[0021] 3. The clamping mechanism of the present invention ensures that the compress is accurately fixed on a specific treatment position to prevent the compress from slipping or shifting during the treatment process. The existence of the clamping mechanism ensures the safety of the patient. By ensuring that the compress or drug material is in close contact with the skin, the clamping mechanism can ensure that ultrasound can more effectively transmit the drug to the patient's skin, thereby ensuring that the drug is maximized and effectively improving the drug penetration efficiency to the patient. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] The present invention can be further understood from the following description in conjunction with the accompanying drawings. The components in the figures are not necessarily drawn to scale, but rather the emphasis is placed on illustrating the principles of the embodiments. In different views, the same reference numerals designate corresponding parts.

[0023] Figure 1 It is a partial structural schematic diagram of the hollow shell of the present invention from a front view.

[0024] Figure 2 It is a schematic diagram of the partial structure of the hollow shell of the present invention when viewed from above.

[0025] Figure 3 It is a partial structural schematic diagram of the clamping unit of the present invention.

[0026] Figure 4 It is another partial structural schematic diagram of the clamping unit of the present invention.

[0027] Figure 5 It is a partial structural schematic diagram of the clamping mechanism of the present invention.

[0028] Explanation of the accompanying drawings: 1-empty shell; 2-fixed plate; 3-first chamber; 4-second chamber; 5-third chamber; 6-second through-port; 7-limiting groove; 8-first through-port; 9-linear groove; 10-shell opening; 11-engaging groove; 12-matching plate; 13-third fixing rod; 14-second driving gear; 15-fourth fixing rod; 16-first bearing ring; 17-second bearing ring; 18-compress; 19-second driving gear; 20-second rotating rod; 21-first rotating rod; 22-first driving gear. DETAILED DESCRIPTION

[0029] In order to make the purpose, technical solutions and advantages of the present invention clearer, the present invention is further described in detail below in conjunction with its embodiments; it should be pointed out that the specific embodiments described herein are only used to explain the present invention and are not used to limit this case. For those skilled in the art, after reviewing the following detailed description, other systems, methods and / or features of this embodiment will become apparent. In addition, the terms describing the positional relationship in the accompanying drawings are only for illustrative purposes and cannot be understood as limiting this patent. For those of ordinary skill in the art, the specific meanings of the above terms can be understood according to the specific circumstances.

[0030] Example 1: Combined with the attached Figure 1 , Attachment Figure 2 , Attachment Figure 3 , Attachment Figure 4 and attached Figure 5 This embodiment constructs an intelligent ultrasonic conductance directional drug penetration therapeutic device, which includes a drug penetration module for applying a drug to the patient's skin by contacting the patient's skin, an adaptation module for adjusting the penetration efficiency of the drug penetration module according to the different skin locations of the patient, and a fixing module for fixing the drug penetration module to different skin locations of the patient.

[0031] The penetration efficiency includes the ultrasonic frequency of the ultrasonic transmitter, the amount of the medicine, and the operation time of the ultrasonic transmitter. The medicine penetration module includes an empty shell, a compress, an ultrasonic conductivity unit arranged in the empty shell, a clamping unit arranged outside the empty shell for automatically clamping and fixing the compress, a medicine delivery unit arranged in the empty shell for outputting the medicine to the compress, a matching plate attached to one end of the empty shell, and a heating unit arranged in the matching plate.

[0032] The ultrasonic conductivity unit includes an ultrasonic transmitter that generates ultrasonic waves of a specific frequency, a controller that controls the switch, frequency and power of the ultrasonic transmitter, and a sensor for monitoring the intensity and frequency of the ultrasonic waves to ensure that they remain within a safe and effective range.

[0033] The adaptation module includes an input interface that allows a user to manually input the skin position to be contacted by the drug permeation module, a database that stores the ultrasonic frequencies of the ultrasonic conductance unit corresponding to the skin of different parts of the human body, an information extraction unit that further retrieves the corresponding ultrasonic frequency from the database based on the skin position received from the input interface, and an instruction sending unit that generates a control instruction based on the data of the information extraction unit and sends it to the control device to control the ultrasonic transmitter to generate the corresponding frequency.

[0034] The adaptation module can be implemented through an application in a terminal device, and the terminal device and the drug permeation module are connected through communication technology signals to realize instruction transmission. The adaptation module can adjust the penetration efficiency of the drug permeation module according to the patient's specific skin location, thereby providing more accurate and personalized treatment.

[0035] By combining ultrasonic technology with specific agents, the skin permeability of drugs can be increased, thereby improving the therapeutic effect. At the same time, the intensity and frequency of ultrasonic waves can be monitored in real time through the sensor in the ultrasonic conductivity unit to ensure that they are always within a safe and effective range. The adaptation module provides an input interface, allowing the user to manually select the contact position of the drug permeation module, providing a more intuitive and convenient use experience. Since the adaptation module is implemented through the application of the terminal device and connected to the drug permeation module through communication technology, this provides patients with greater mobility and portability. The present invention provides a drug permeation therapeutic device that integrates safety, efficiency, portability and intelligence, which can provide patients with a more efficient and personalized treatment experience.

[0036] Example 2: Combined with the attached Figure 1 , Attachment Figure 2 , Attachment Figure 3 , Attachment Figure 4 and attached Figure 5 In addition to the contents of the above embodiments, the heating unit includes a plurality of inner channels respectively disposed inside the matching plate and heating strips respectively disposed in each inner channel; the hollow shell includes an open shell opening disposed in the middle region of one end of the shell wall and having an open structure, and three chambers disposed inside the hollow shell and separated from each other by baffles.

[0037] The three chambers are sequentially labeled as a first chamber, a second chamber, and a third chamber, wherein the second chamber is located between the first chamber and the third chamber, and the shell opening passes through and communicates with the second chamber, wherein the opening edge of the shell opening is provided with a snap-fit ​​groove, and the side wall of the mating plate is provided with a snap-fitting groove that is snap-fitted with the snap-fitting groove, and the mating plate is fixed to the shell opening by snapping and fixing the snap-fitting groove with the snap-fitting groove.

[0038] The outer wall of the shell on the side where the shell opening is located is the working wall, and the empty shell further includes two linear grooves symmetrically arranged on the working wall, two limiting grooves symmetrically arranged on the working wall, a first through-port arranged on the working wall for connecting the first chamber with the outside of the empty shell, and a second through-port arranged on the working wall for connecting the third chamber with the outside of the empty shell.

[0039] The linear groove and the limiting groove are arranged perpendicular to each other, and the two ends of the limiting groove extend to be connected with the two linear grooves respectively. The ultrasonic transmitter is arranged in the second chamber, and the ultrasonic transmitter abuts against the matching plate, and the matching plate abuts against the patient's skin, thereby transmitting ultrasonic waves to the patient's skin and promoting the efficiency of applying medicine to the patient.

[0040] The clamping unit includes an infrared sensor embedded in the working wall and two clamping mechanisms symmetrically arranged on the working wall for clamping and fixing the compress on the empty shell. The infrared sensor is used to detect whether the compress on the working wall exists. When the compress exists, the medicine delivery unit is allowed to perform the medicine delivery operation.

[0041] The medicine delivery unit includes a medicine tank stored in the first chamber, a medicine outlet provided on the medicine tank, a connection port provided on the working wall and connected to the first chamber, a liquid outlet nozzle provided through the connection port, a transmission pipe provided with one end connected to the medicine outlet and the other end connected to the medicine outlet nozzle, a one-way valve provided in the transmission pipe, and a liquid pump for quantitatively driving the medicine in the medicine tank to be transferred from the transmission pipe to the medicine outlet.

[0042] The medicine tank is filled with the patient's treatment medicine in advance. When the clamping mechanism fixes the compress to the working wall, the liquid outlet is blocked by the compress. Then, when the medicine delivery unit performs the medicine delivery operation, the medicine is delivered to the compress. Under the ultrasonic transmission of the matching plate, the medicine on the compress is promoted to enter the skin.

[0043] The fixing module includes at least two fixing plates symmetrically and vertically connected to the side walls of the hollow shell, and a medical dressing partially adhered to the fixing plates and partially used to adhere to human skin, wherein the medical dressing is manually adhered to the fixing plates or torn off from the fixing plates.

[0044] The present invention integrates ultrasonic treatment, drug delivery, infrared sensing and compress clamping functions, realizing the combined application of multiple treatment methods. Ultrasonic technology is used to make it easier for drugs to penetrate into the patient's skin, thereby improving the utilization rate of drugs. The infrared sensor can intelligently detect whether a compress has been applied to the patient, ensuring that the drug delivery operation is not started until a compress is present, thereby improving safety. Integrating multiple treatment and detection functions into one device can save medical resources and costs, and provide an efficient, safe and personalized treatment experience.

[0045] Example 3: Combined with the Figure 1 , Attachment Figure 2 , Attachment Figure 3 , Attachment Figure 4 and attached Figure 5In addition to the contents of the above embodiments, the two clamping mechanisms are respectively a first clamping mechanism and a second clamping mechanism, the first clamping mechanism including two first bearing rings respectively embedded in one of the linear grooves, a first rotating rod sleeved in the two bearing rings in one of the linear grooves and capable of axially rotating and fitting in the linear groove, a first driving gear sleeved on the outer wall of the rotating rod, a first driving gear rotatably fixed in the first chamber and at least partially extending from the first through-hole to engage with the driving gear, a first reduction motor disposed in the first chamber for driving the first driving gear to rotate the axis, a second fixing rod having one end fixed to the first rotating rod, and a second fixing rod having one end fixed to the first rotating rod, the first rotating rod being driven by the first reduction motor on the first driving gear to achieve axial rotation in the linear groove, and during the axial rotation of the first rotating rod, the first fixing rod and the second fixing rod can respectively fit into two different limiting grooves,

[0046] The second clamping mechanism includes two second bearing rings respectively embedded in another linear groove, a second rotating roller sleeved in the two bearing rings in the other linear groove and capable of axially rotating and cooperating with the linear groove, a second driving gear sleeved on the outer roller wall of the rotating roller, and a second driving gear rotatably fixed in the third chamber and at least partially extending from the second through-hole to engage with the driving gear for transmission, a second reduction motor arranged in the third chamber for driving the second driving gear to rotate the axis, a third fixing rod with one end fixed to the second rotating roller, and a fourth fixing rod with one end fixed to the second rotating roller. Through the driving operation of the second driving gear by the second reduction motor, the second rotating roller realizes axial rotation in the linear groove. During the axial rotation of the second rotating roller, the third fixing rod and the fourth fixing rod can respectively engage with two different limiting grooves.

[0047] The clamping mechanism of the present invention can ensure that the compress is accurately fixed on a specific treatment position to prevent the compress from slipping or shifting during the treatment process. The existence of the clamping mechanism ensures the safety of the patient. By ensuring that the compress or drug material is in close contact with the skin, the clamping mechanism can ensure that ultrasound can more effectively transmit the drug to the patient's skin, thereby ensuring that the drug is maximized and effectively improving the drug penetration efficiency to the patient.

[0048] Although the present invention has been described above with reference to various embodiments, it will be appreciated that many changes and modifications may be made without departing from the scope of the present invention. That is, the methods, systems, and devices discussed above are examples. Various configurations may omit, replace, or add various processes or components as appropriate. For example, in alternative configurations, the methods may be performed in an order different from that described, and / or various components may be added, omitted, and / or combined. Moreover, the features described with respect to certain configurations may be combined in various other configurations, such as different aspects and elements of the configurations may be combined in a similar manner. In addition, as technology develops, the elements therein may be updated, i.e., many elements are examples and do not limit the scope of the present disclosure or claims. It will also be appreciated that, after reading the contents of the present invention, a technician may make various changes or modifications to the present invention, and these equivalent changes and modifications also fall within the scope defined by the claims of the present invention.

Claims

1. An intelligent ultrasonic conductance directional drug penetration therapeutic device, characterized in that: The device comprises a drug permeable module for applying medicine to the patient's skin by contacting the patient's skin, an adaption module for controlling the permeation efficiency of the drug permeable module according to different skin positions of the patient, and a fixing module for fixing the drug permeable module to different skin positions of the patient. The penetration efficiency includes the ultrasonic frequency of the ultrasonic transmitter, the amount of the medicine, and the operation time of the ultrasonic transmitter. The medicine penetration module includes an empty shell, a compress, an ultrasonic conductivity unit arranged in the empty shell, a clamping unit arranged outside the empty shell for automatically clamping and fixing the compress, a medicine delivery unit arranged in the empty shell for outputting the medicine to the compress, a matching plate attached to one end of the empty shell, and a heating unit arranged in the matching plate. The heating unit includes a plurality of inner channels respectively arranged inside the matching plate, and heating strips respectively arranged in each inner channel. The hollow shell includes a shell opening arranged in the middle area of ​​the shell wall at one end and having an open structure, and three chambers arranged inside the hollow shell and separated from each other by baffles. The three chambers are labeled as the first chamber, the second chamber, and the third chamber in sequence, wherein the second chamber is located between the first chamber and the third chamber, and the shell opening passes through and connects to the second chamber, wherein the opening edge of the shell opening is provided with a snap-fit ​​groove, and the side wall of the mating plate is provided with a snap-fitting groove that is snap-fitted and fixed with the snap-fitting groove, and the mating plate is fixed to the shell opening by snapping and fixing the snap-fitting groove with the snap-fitting groove, and the outer wall of the shell on the side where the shell opening is located is the working wall.

2. The directional drug-penetrating therapeutic device according to claim 1, characterized in that: The ultrasonic conductivity unit includes an ultrasonic transmitter that generates ultrasonic waves of a specific frequency, a control device that controls the switch, frequency and power of the ultrasonic transmitter, and a sensor for monitoring the intensity and frequency of the ultrasonic waves to ensure that they remain within a safe and effective range. The ultrasonic transmitter is arranged in the second chamber, and the ultrasonic transmitter abuts against the matching plate, and the matching plate abuts against the patient's skin.

3. The directional drug penetration therapeutic device according to claim 2, characterized in that: The adaptation module includes an input interface for allowing a user to manually input a skin location to be contacted by the drug permeation module, a database storing ultrasonic frequencies corresponding to the ultrasonic conductivity unit operation at different parts of the human body, an information extraction unit that further retrieves the corresponding ultrasonic frequency from the database based on the skin location received from the input interface, and an instruction transmission unit that generates a control instruction based on the data of the information extraction unit and transmits it to the control device to control the ultrasonic transmitter to generate the corresponding frequency; The hollow shell further includes two linear grooves symmetrically arranged on the working wall, two limiting grooves symmetrically arranged on the working wall, a first through-hole arranged on the working wall for connecting the first chamber with the outside of the hollow shell, and a second through-hole arranged on the working wall for connecting the third chamber with the outside of the hollow shell. The linear groove and the limiting groove are arranged perpendicular to each other, and the two ends of the limiting groove extend to be connected with the two linear grooves respectively; The clamping unit includes an infrared sensor embedded in the working wall and two clamping mechanisms symmetrically arranged on the working wall for clamping and fixing the compress on the empty shell. The infrared sensor is used to monitor whether a compress exists on the working wall, and when a compress exists, the medicine delivery unit is allowed to perform the medicine delivery operation; The medicine delivery unit includes a medicine tank stored in the first chamber, a medicine outlet arranged on the medicine tank, a connecting port arranged on the working wall and connected to the first chamber, a liquid outlet nozzle arranged through the connecting port, a transmission pipe connected to the medicine outlet at one end and the liquid outlet nozzle at the other end, and a one-way valve arranged in the transmission pipe, and a liquid pump for quantitatively driving the medicine in the medicine tank to be transferred from the transmission pipe to the medicine outlet.

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