705results about How to "Wide range of substrates" patented technology

The invention belongs to the environmental microorganism field, and in particular relates to a heterotrophic nitrification microorganism agent, a method for cultivating the same, and a use of the same in culture wastewater treatment. The microorganism agent contains Stenotrophomonas maltophilias strain DN1.1 and Pseudomonas putida strain DN1.2 which have the preservation registration numbers respectively as CCTCC M 207074 and CCTCC M 207075. The microorganism agent can effectively remove ammonia nitrogen and total nitrogen in a water body, accumulates no nitrite or nitrate during denitrification, and can simultaneously remove CODCr in organic wastewater, which is applicable to the treatment of high-concentration culture wastewater. The use of the microorganism agent in treating culture wastewater is simple in process and stable in effect.

The invention belongs to the environmental microorganism field, relates to a high efficiency heterotrophic nitration aerobic denitrifying bacteria and the culture method and the purpose. The bacterium is Pseudomonas putida DN1.2 with the preservation and registration number of CCMCC M207075, which can effectively remove the ammonia nitrogen, nitrous acid and the mixture in water. At the same time, the bacterium also can remove the CODCr in the organic waste water. The bacterium is suitable for being used in the treatment of organic nitrogenous effluent with high concentration and inorganic nitrogenous effluent. The nitrite and nitrate can not be produced in the denitrification process. The waste water treatment process is simple by using the strain and the denitrification effect is stable.

The invention discloses a plant cultivation medium and its preparation method. The cultivation medium includes a garden greening waste compost, vinegar residues and turf, and is prepared through blending the garden greening waste compost, vinegar residues and turf according to a volume ratio of 3-6:2-3:2-6. The cultivation medium improves the physical and chemical properties of original mediums, reduces the application amount of a nonrenewable medium turf which is massively used in the production of flowers at present, allows the vinegar residues and garden greening wastes to be massively used to realize changing of wastes into valuables and resource recycle, and has obvious social, ecologic and economic benefits.

The invention belongs to the technical field of environmental microbiology, and relates to high-efficiency heterotrophic nitrification aerobic denitrifying bacteria and a culture method and application thereof. The bacteria are Rhodococcus sp. DN2.3 with the preservation registration number of CCTCC M209300, can effectively remove ammonia nitrogen, nitrite nitrogen, nitric nitrogen and the mixture thereof from a water body, also can remove CODCr from organic wastewater, are suitable for treating high-concentration organic nitrogen-containing wastewater; the accumulation of nitrite and nitrate is avoided in the denitrifying process; and the process for treating wastewater by using the strain is simple and the denitrifying effect is stable.

The invention discloses a novel method for synthesizing an N-substitute amide derivative. The novel method is characterized by comprising the steps that at the air atmosphere, no catalyst or alkali or other any additives are added, an organic amine compound shown in a formula (I) is adopted as a reaction substrate, a solvent shown in a formula (II) is adopted as an acylation reagent, an acylation reaction is performed under the reaction temperature of 120-150 DEG C to generate the N-substitute amide derivative shown in a formula (III), and the equation is shown in the description. The novel method has the advantages that environmental protection is achieved, and post-treatment and product separation are easy; the range of the substrate is wide, and the substrate can be primary amine and can also be secondary amine; the solvent can be amide and can also be carboxylic acid, and the solvent can be adopted as the acylation reagent to participate in the reaction; the reaction efficiency is high, and the majority of reactions can reach the quantified yield; water and air have no effect on the reaction, inert gas shielding is not needed, and operation is easy.

The invention discloses a copper catalyst system for decarboxylation coupling reaction, which comprises a copper-containing compound and an oxidant in a mol ratio of 1:(10-40), wherein the copper-containing compound is one or mixture of cuprous iodide, cupric acetylacetonate, cuprous bromide, cupric sulfate and copper powder; and the oxidant is tert-butyl hydroperoxide, di-tert-butyl peroxide or dicumyl peroxide. The catalyst system can catalyze the decarboxylation coupling reaction of cinnamic acid and methylbenzene compounds to prepare olefin compounds. Compared with the existing noble-metal-containing catalyst system, the catalyst system disclosed by the invention uses the cheap copper-containing compound instead of noble metal, thereby lowering the cost; and the byproduct is only carbon dioxide, thereby being beneficial to environment protection and cost saving, and satisfying the requirement for green chemistry.

A liquid chromatogram-tandem-mass spectrometry method for simultaneously detecting five types of medicines in animal edible products and feed is disclosed. The five types of medicines are epinephrinetype medicines, steroid hormones, psychotropic medicines, coloring agents and antioxidants. The method belongs to the technical field of medicine residual detection and analysis. The method includes two steps, namely a step of sample pretreatment and a step of liquid chromatogram-tandem-mass spectrometry detection. The method enriches and completes present detection techniques, can simultaneouslymeasure 88 medicines, and is simple, convenient and rapid to operate, and suitable for simultaneous detection of a plurality of medicines in feed and a plurality of animal foods.

The invention discloses a polysubstituted pyridine derivative and a preparation method thereof. The derivative has a structure as shown in specification, wherein R1, R2, R3, R4 and R5 all are any one selected from hydrogen atom, halogen atom, alkyl, aryl, substituted aryl, acyl, amino, nitryl and alkoxy; the invention also discloses a preparation method of the polysubstituted pyridine derivative; the preparation method comprises the following steps: by taking acetyenic ketone and 1-arylethylamine as raw materials, and under the action of appropriate alkali, heating to have a reaction in the solvent to obtain the polysubstituted pyridine derivative as shown in the formula at high yield. The preparation method is mild in reaction condition, short in reaction time, wide in substrate range, high in reaction specifity, high in yield and simple in after-treatment.

The invention discloses a fluorescent transparent coating capable of realizing full colors. The fluorescent transparent coating comprises quantum dots and ultraviolet (UV) curing transparent ink. A method for preparing the fluorescent transparent coating comprises the following steps of: adding the quantum dots and the UV curing transparent ink into a charging bucket, and stirring by using a dispersion machine for 30 to 120 minutes; adding zirconium oxide beads of which the grain diameters are 0.2 millimeter, and grinding for 3 to 8 hours; printing the ground UV curing transparent ink containing the quantum dots on a base material by using an inkjet printer to form a target image; and irradiating by using ultraviolet light while printing the target image or after the target image is printed. According to the fluorescent transparent coating, the quantum dots which can emit fluorescent light of different wavelengths and the UV curing transparent ink are combined to realize full colors, and the image is printed by using the UV curing transparent ink through the inkjet printer; and the method is simple, high in efficiency and flexible and can be used for large-area inkjet, and the coating is high in curing speed and environment-friendly.

The invention discloses a trifluoromethylthio reagent as well as a synthetic method and application thereof and provides a compound I and a preparation method of the compound I. The preparation method comprises the step: reacting a compound 1a with trifluoromethylthio silver, so as to obtain the compound 1, wherein the reaction is as shown in the specification. The invention further provides application of the compound 1 as the trifluoromethylthio reagent. The compound 1 can react with amine compounds, thiol or phenolic compounds to generate the compound containing trifluoromethylthio. The trifluoromethylthio reagent 1 has the beneficial effects of high efficiency, conversion rate and yield, mild reaction conditions, low production cost and wide applicable range and is applicable to industrial production.

The invention discloses a COF material-loaded transition metal catalyst, and a preparation method and application thereof. The COF material-loaded transition metal catalyst comprises a COF material and Pd<2 +> or Ni <2+> loaded on the COF material. The preparation method comprises the following steps: 1) mixing an aldehyde precursor, an amine precursor and absolute ethyl alcohol, carrying out a full reaction, and separating and purifying a reaction product to obtain a COF material; and 2) mixing the COF material, a soluble Pd salt or soluble Ni salt and dichloromethane, carrying out impregnation loading, and separating and purifying the obtained product. The COF material-loaded transition metal catalyst has the advantages of high catalytic activity, good selectivity, wide substrate application range, easiness in recycling, mild reaction conditions, usage of green and environment-friendly reaction solvents and the like when used for a semi-hydrogenation reaction of phenylacetylene compounds, and is simple in preparation process, easily available in raw materials and low in production cost.

The invention discloses a benzimidazole chiral heterocyclic compound as well as a preparation method and application thereof. The structure formula of the benzimidazole chiral heterocyclic compound isshown in formula I, formula II or formula III in the description. The benzimidazole chiral heterocyclic compound is prepared by treating an iridium complex which is prepared through a metal iridium compound and a phosphoramidite ligand as a catalyst, performing intra-molecular allyl amination on allyl substrate, and then synthesizing with high efficiency and high enantioselectivity. The method has the advantages of being high in catalytic reaction activity, mild in reaction conditions, high in enantioselectivity, wide in substrate applicable scope, and environmentally friendly; the primary in-vitro enzyme inhibition activity test shows that the compound is high in alpha-glucosidase inhibiting activity and can be used as an alpha-glucosidase inhibiting agent, and the compound can also be used as a further modified drug intermediate; the compound has a potential application value in preventing or treating II-diabetes, obesity and complication medicines thereof and pilot compounds thereof.

The invention discloses a covalent organic framework material loaded Pd catalyst and a preparation method and application thereof. The covalent organic framework material loaded Pd catalyst comprisesa covalent organic framework material and Pd2+ loaded on the covalent organic framework material. The preparation method comprises the following steps: 1) mixing an aldehyde precursor, an amine precursor and absolute ethyl alcohol, carrying out aldehyde-amine condensation reaction, and separating and purifying the product to obtain a covalent organic framework material; and 2) mixing the covalentorganic framework material, soluble Pd salt and dichloromethane, carrying out impregnation loading, and separating and purifying the product. The covalent organic framework material loaded Pd catalystdisclosed by the invention has the advantages of high catalytic activity, good selectivity, the wide substrate application range, easiness in recycling, mild reaction conditions, the green and environment-friendly reaction solvent and the like when being used for Suzuki reaction, and is simple in preparation process, easily available in raw materials, low in production cost and the like.

The invention discloses a method for preparing 6-difluoro alkyl ketone. The method includes mixing allylbenzene formaldehyde, phenylboronic acid, monobromo difluoro acetic ester, palladium catalysts, alkali and solvents with one another to form reaction systems; carrying out reaction and then treating reaction products to obtain the 6-difluoro alkyl ketone with the structure shown in a formula I. The structure of the allylbenzene formaldehyde is shown in a formula II. The method has the advantages that 1, n-hydrogen atom transfer radical addition strategies are applied to remote aryl difluoro alkylation for alkene, three-component reaction is completely carried out on monobromo difluoro methyl compounds, the allylbenzene formaldehyde and boric acid by means of palladium catalysis, accordingly, the 6-difluoro alkyl ketone can be synthesized by the aid of one-pot processes, reaction conditions are mild, the method is easy to implement and excellent in yield and has excellent theoretical value and an excellent application prospect, functional groups are good in compatibility, and substrates are wide in applicability.

The invention belongs to the technical field of organic synthesis, and particularly relates to application of a cyclopalladated ferrocenylimines-phosphine adduct in the synthesis of a cyclopropyl alkyl aromatic compound. Halogenated aromatic hydrocarbon Aryl-X, alkali and cyclopropyl borate which serve as raw materials, and the cyclopalladated ferrocenylimines-phosphine adduct is used as a catalyst. The catalyst has high stability, efficient catalytic activity and wide application range, and a corresponding coupling product can be synthesized in a mode of high yield (which is up to 96 percent) on the premise of small catalytic quantity; and the method is mild in reaction condition, wide in range of substrates and high in specifity of reaction.

The invention relates to the technical field of synthesis of organic compounds and particularly relates to a preparation method of a beta-hydroxyphenyl selenide compound. The preparation method comprises the step of with aryl boronic acid with a structure presented by a formula (I), elemental selenium and an ethylene oxide derivative presented by a formula (II) as the raw materials, and carrying out insertion reaction on elemental selenium in a reaction solvent under the common effect of a copper catalyst, silver salt and alkali, so as to obtain the beta-hydroxyphenyl selenide compound represented by a formula (III), wherein R1 and R2 are respectively independently selected from one of H, a benzene ring, a naphthalene ring, a heterocyclic ring, a substituted benzene ring, linear alkyl, branched chain, halogen, nitryl and a cyano group.

The invention relates to a synthetic method of an alpha-hydroxyl carbonyl compound. The method is as below: mixing a carbonyl compound (I) with an organic phosphorus compound in an organic solvent; adding a catalyst cesium carbonate; and reacting under aerobic conditions to obtain the alpha-hydroxyl carbonyl compound (II). R1 is selected from the group consisting of hydrogen, alkyl, alkoxy, amino, aromatic base, substituted aromatic base and heterocyclic aromatic base; R2 is selected from alkyl, carbonyl, ester and phenyl; R3 is selected from alkyl, carbonyl, ester group and phenyl. Or, R1 combines with R2 to form naphthenic group or substituted cycloalkyl, benzo cycloalkyl base or substituted benzo cycloalkyl base, indole ring or substituted indole ring. Or, R2 combines with R3 to form the cycloalkyl or substituted cycloalkyl. The organic phosphorus compound is triphenylphosphine or triethyl phosphate. The organic solvent is dimethyl sulphoxide, N,N-dimethyl formamide, N,N-dimethyl acetamide or N-methyl pyrrolidone.

The invention discloses a method for preparing substituted alkene. The method is characterized in that Suzuki coupling reaction and Heck coupling reaction occur in turn under the action of a catalyst with a vinyl fluoride potassium silicate compound and halogenated hydrocarbon as a reaction substrate to obtain the substituted alkene, wherein the halogenated hydrocarbon is a halogenated aromatic hydrocarbon or a halogenated aliphatic hydrocarbon, the halogen atom is selected from chlorine, bromine or iodine; the vinyl fluoride potassium silicate compound refers to an olefin compound with double bond connected with boric acid group, the catalyst is a palladium catalyst. The method provided by the invention has the advantages of simple operation, mild condition, convenient post-processing, easiness of geting raw materials and wide range of suitable substrates.

The invention discloses nail-free glue and a preparation method thereof, and belongs to the field of a binding agent. The nail-free glue is characterized in that the sealant consists of the following components in parts by weight: 100 parts of silane-terminated polyether, 70-140 parts of a plasticizer, 1-4 parts of a water removal agent, 0.5-4 parts of a stabilizer, 120-420 parts of filler, 3-6 parts of an adhesion accelerant and 2-5 parts of a catalyst. The product disclosed by the invention is free from volatile solvent component in a component formula, environmentally friendly and free from harm, and has performances of fast hardening, excellent mechanical property and adhesion property, heat resistance, water resistance, aging resistance and the like; and the nail-free glue can be widely applied to the binding of such base materials as stone, glass, wood, metal, plastic and the like.

The invention relates to a preparation method of RFID antenna-based inkjet conductive ink, and also relates to the making of an RFID antenna by utilizing the ink. The preparation process of the ink mainly comprises the following steps: preparing by simple ion exchange reaction to obtain silver source precursor precipitates, filtering by a special aperture filter membrane, drying, and grinding to obtain silver source precursor powder; sufficiently mixing a complexing agent, an additive and other auxiliaries in virtue of a magnetic stirrer to obtain homogeneous solution; adding the silver source precursor powder with a small amount into the solution for multiple times, and sufficiently dissolving and reacting to obtain the clear and transparent solution, namely the particle-free conductive ink. Then the RFID antenna is obtained by making in an inkjet printing way. The prepared particle-free conductive ink does not contain any solid particle per se, so particle agglomeration cannot occur, and spray nozzle jamming cannot be caused; the particle dispersion problem does not exist as well, and after sintering, a uniform and compact conductive silver membrane can be formed on the surface of a printed base material, so better matching between the ink and an inkjet print head can be realized.

The invention relates to a simple and efficient preparation method of 1, 3-two substituted ureas and carbamate. The method comprises the steps as follows: amide is taken as substrate, and the 1, 3-two substituted ureas and carbamate are prepared by using Hofmann rearrangement reaction induced by hypervalent iodine. Only acid amide and oxidization iodobenzene are added into the reaction system, stirring is performed for 2 hours in methylene dichloride at a room temperature, and symmetrical 1, 3-two substituted ureas can be obtained with high yield. When acid amide, oxidization iodobenzene and nucleophilic agent amine are in reaction, and stirring is performed for 2 hours in methylene dichloride at a room temperature, unsymmetrical 1, 3- two substituted ureas can be obtained. When acid amide, oxidization iodobenzene and nucleophilic agent alcohol are in reaction, and stirring is performed for 2 hours in alcoholic solution at a room temperature, carbamate can be prepared. The method is simple to operate, the product selectivity is strong, and the application is wide.

The invention provides a method for performing gold-catalyzed selective C-H bond functionalization on phenol and aniline, which comprises the following steps: by taking phenol and aniline compounds as raw materials and taking phosphine ligand or carbene as ligand, in organic solvent, reacting with a diazo compound in the presence of a gold catalyst and a silver salt, performing carbon-hydrogen bond insertion at the para-position or ortho-position of the phenol or aniline structure. The method provided by the invention has the characteristics of low catalyst consumption, mild conditions, wide substrate application range and the like; the method can be used for quickly and efficiently synthesizing methyl acetate derivatives containing the phenol or aniline structure; and meanwhile, the method can be used for performing later modification on natural products or drug molecules (such as estrone), or be used for synthesizing some molecules having biological activity, thus having favorable application prospects.

The invention relates to an organic solvent resistant protease producing strain, a gene of organic solvent resistant protease and an application of the organic solvent resistant protease, in particular relating to the organic solvent resistant protease producing strain as well as the gene of the organic solvent resistant protease thereby and the application of the organic solvent resistance protease in catalytic synthesis of small peptides in nonaqueous phases, belonging to the fields of microbiology and enzymology. Bacterial strains are named as Bacilluscereus WQ9-2 by classification, are gram-positive strains and can resist a plurality of organic solvents with a certain concentration. The protease-coding gene which is separated and cloned on organic solvent resistant protease produced by the producing strain is provided with a nucleotide sequence shown as SEQ ID NO:1, and an amino acid sequence shown as SEQ ID NO:2. The protease has the characteristics of high yield, high specific activity, wide and strong tolerance and the like. The protease has industrial application value for the catalytic synthesis of the small peptides in the nonaqueous phases.

The invention belongs to the field of medical chemical industry intermediates and related chemical technologies, relates to a preparation method of a pyrazol compound and a related chemical technology, and in particular provides a method for synthesizing a novel pyrazol compound based on terminal alkyne. The preparation method is characterized in that the terminal alkyne and hydrazine are used as raw materials, and the novel pyrazol compound is synthetized in two steps by one boiler under the catalysis of Cu. The invention mainly provides the novel pyrazol ring synthetic method which has the advantages of being mild in reaction condition, excellent in functional group compatibility, wide in substrate scope, environment-friendly and the like. Because the pyrazol ring is an important biological active group and is used very widely in the medicine field, the preparation method provided by the invention has relatively high application value and social economic benefits.

The invention discloses a preparation method of a pyrimidine nucleoside compound shown in a formula 1 or a purine nucleoside compound shown in a formula 2, comprising the following steps of: performing glucosidation on a compound 3 and a compound 4 to obtain the pyrimidine nucleoside compound 1; or performing glucosidation on the compound 3 and a compound 5 to obtain the purine nucleoside compound 2. The preparation method disclosed by the invention is applicable to preparation of many kinds of nucleoside compounds, and has the advantages of mild reaction conditions, greenness, environmental friendliness and higher yield and purity of the product.

The invention belongs to the anti-fake field, especially relates to a method of anti fake by utilizing the visible random structure character. The invention discloses a method of anti fake by utilizing the visible random structure characteristic an tifake method, wherein the key is that the visible random structure characteristic adopts the printing ink or paint during the printing and daubing-upprocess or the visible random structure character after the printing or daubing cup process.

The invention relates to a synthesis method of an NH-1,2,3-triazole compound and belongs to the technical field of organic and drug synthesis. In the presence of a Lewis acid catalyst, the NH-1,2,3-triazole compound is prepared from aromatic aldehyde, nitro-hydrocarbon and sodium azide by adopting a one-pot process. The synthesis method of the NH-1,2,3-triazole compound has the beneficial effects that available Lewis acids such as AlCl3 are taken as the catalyst, one-pot reaction is carried out on aromatic aldehyde, a nitro-hydrocarbon compound containing alpha hydrogen (wherein hydrocarbon is C1-C6 alkyls, C1-C6 alkoxys or ethyl formate) and sodium azide, reaction conditions are mild, yield is high, raw materials are available, the NH-1,2,3-triazole compound is conveniently and effectively synthesized, and compared with an existing method, the synthesis method provided by the invention is mild in reaction conditions, short in reaction time, good in safety, simple in operation, wide in substrate range and high in reaction efficiency and adopts a cheap catalyst, so that the synthesis method provided by the invention has potential application value.

Disclosed are methods for synthesizing an ester or a carboxylic acid from an organic alcohol. To form the ester one reacts, in the presence of oxygen gas, the alcohol with methanol or ethanol. This reaction occurs in the presence of a catalyst comprising palladium and a co-catalyst comprising bismuth, tellurium, lead, cerium, titanium, zinc and / or niobium (most preferably at least bismuth and tellurium). Alternatively that catalyst can be used to generate an acid from that alcohol, when water is also added to the reaction mix.

The invention discloses a preparation method for a diphenyl diselenium compound. According to the method, an arylboronic acid compound and elemental selenium serve as reaction raw materials, an organic solvent serves as a reaction solvent, under the effect of a silver catalyst, reaction is carried out so as to obtain the diphenyl diselenium compound, the reaction temperature is 100-140 DEG C, thereaction equation is shown in the specification, wherein R is a benzene ring, a naphthalene ring, a heterocyclic ring or a substituted benzene ring. The method has the beneficial effects that the tolerance of functional groups of substrates is high, and the range of the substrates is wide; and the raw materials and the catalyst are cheap and easily available, the conditions are mild, the post-treatment is simple, the yield and purity of a product are high, and the method is suitable for large-scale industrial production.

The invention discloses agranular type silver-based conductive ink. The agranular type silver-based conductive ink is prepared from the following raw materials in percentage by weight: 20-55% of a metal silver salt, 30-50% of an alcohol amine solution, 10-30% of a reducing agent and 0.3-0.5% of an additive, wherein the metal silver salt is at least one of silver nitrate, silver citrate and silver acetate; the alcohol amine solution is prepared by mixing an alcohol solvent and an amine solvent in a volume ratio of 1: (0.5-3); the reducing agent is at least one of ascorbic acid and formic acid; and the additive is at least one of curdlan and carboxymethyl cellulose sodium. The invention further discloses a preparation method for the conductive ink and the application in preparing an RFID label antenna. The conductive ink disclosed by the invention is strong in stability, low in thermal treatment temperature, simple in preparation method and easy to realize industrial production.