235 results about "Platinum nanoparticle" patented technology

The invention discloses an anode material for adipic acid monoester electrolysis and a preparation method of the anode material, the electrode solves the key problems that a platinum layer is easy to fall off, the catalytic activity is low, the organic matter poisoning resistance is poor and the like of a traditional titanium platinum-plated electrode through multi-scale interface strengthening and nano structure regulation and control; the preparation method comprises the following core steps: constructing a porous ZrO2-TiO2 composite oxide layer on the surface of a titanium substrate by adopting a micro-arc oxidation-hydrothermal composite process, and generating platinum nanoparticles in situ to pre-fill pores, so that the anchoring effect of a platinum layer is remarkably enhanced; depositing a platinum / carbon nano tube (Pt / CNT) composite catalyst layer on the surface of the oxide layer through a pulse-ultrasonic synergistic electroplating technology, wherein the carbon nano tube is used as a conductive framework to inhibit platinum agglomeration; through vacuum annealing and electrochemical activation treatment, the interface bonding force and active site exposure are further optimized; the electrode shows excellent performance in an adipic acid monoester electrolysis system, and efficient electrocatalytic conversion from adipic acid monomethyl ester to dimethyl sebacate is achieved.

The invention discloses an immunosensor for detecting cytokine interferon gamma through electrochemiluminescence as well as a preparation method and application of the immunosensor. The immunosensor comprises a three-electrode system consisting of an immunoelectrode, a reference electrode and a counter electrode, the immunoelectrode is a VMSF modified electrode confined to cerium dioxide nano enzyme and platinum nano particles, and is obtained by covalently immobilizing an IFN-gamma antibody and closing a non-specific site; when the immunosensor is used for detection, a solution containing luminol is used as an electrolyte. The CeO2 and the PtNPs which are confined in the nano channel show a remarkable synergistic catalysis effect. Compared with direct modification on a plate electrode, CeO2-PtNPs has higher catalytic activity and stability. The sensor provided by the invention is used for INF-gamma detection, has the advantages of high sensitivity, low detection limit and wide detection range, does not need complex pretreatment and separation processes during detection, reduces the detection cost, is simple to operate, and is suitable for large-scale application.

The application discloses an electrochemiluminescence immunosensor for detecting interleukin-1 beta and a preparation method and application thereof, and comprises a three-electrode system of a working electrode, a reference electrode and a counter electrode; the working electrode is a modified electrode of CoAl layered double hydroxide, is loaded with platinum nanoparticles after being etched by alkali, and is obtained by fixing interleukin-1 beta antibodies and blocking non-specific sites; and a solution containing luminol is used as an electrolyte during detection of the immunosensor. The working electrode of the immunosensor takes oxygen-rich vacancy CoAl layered double hydroxide as a substrate, combines with platinum nanoparticles to realize EMSI effect, significantly enhances the electrochemiluminescence signal of a luminol-dissolved oxygen system, realizes quantitative detection of IL-1 beta by combining with specific antigen-antibody recognition, and has the characteristics of strong anti-interference ability, fast detection speed and good stability.

The invention discloses a sensing material for detecting atmospheric carboxylic acid, a preparation method, a detection method and application, belongs to the technical field of environmental functional materials, and solves the problems that an existing method is complex in operation and cannot realize real-time online monitoring, the sensing material for detecting atmospheric carboxylic acid is an MOF-802-EDTA-Pt composite film, and the preparation method comprises the following steps: taking 1, 3, 4, 5-tetramethyl-1, 3, 5-tetramethyl-1, 3, 5-tetramethyl-1, 3, 5-tetramethyl-1, 3, 5-tetramethyl-1, 3, 5- The preparation method comprises the following steps: synthesizing an MOF-802 material through a hydrothermal reaction by taking 1, 3, 5-benzene tricarbonic acid (BTC) and aluminum nitrate as raw materials and ethylene diamine tetraacetic acid (Na-EDTA) as a ligand; the preparation method comprises the following steps: dispersing MOF-802 in DMF to form a coating solution, and forming a film on a glass substrate through a pulling method; and then loading platinum nanoparticles, and carrying out solvothermal reaction and vacuum drying to obtain the composite sensing film. The MOF-802-EDTA-Pt composite film has a porous structure and fluorescence characteristics, and detection is realized through a fluorescence quenching effect of carboxylic acid molecules and an MOF skeleton. The method disclosed by the invention is controllable in process and high in material stability, still keeps excellent selectivity under the coexistence condition of interferents such as CO2 and NO2, and is suitable for real-time monitoring of carboxylic acid pollutants in the atmospheric environment.

The invention belongs to the field of antibiotic detection and biosensors, and particularly relates to a colorimetric array sensor for distinguishing different types of antibiotics based on platinum-based nano-enzyme and a detection method of the colorimetric array sensor. The colorimetric array sensor is composed of platinum nano-enzymes with three different structures, namely platinum nano-particles PtNPs, platinum nano-flowers PtNFs and gold-core platinum-shell nano-particles Au (at) PtNPs. According to the antibiotic detection method based on the platinum nano-enzyme colorimetric array sensing system, the peroxidase-like activity of the antibiotics is regulated and controlled through the non-specific interaction of the three platinum nano-enzymes (PtNPs, PtNFs and Au-coated PtNPs) and the antibiotics, a unique'fingerprint 'map is generated in combination with TMB-H2O2 chromogenic reaction, and efficient distinguishing and concentration detection of various antibiotics are achieved.

The invention discloses a method for detecting aflatoxin B1 in coffee based on colorimetric and photo-thermal dual modes of MXene (at) Pt nano-enzyme, which comprises the following steps: etching Ti3AlC2 by using LiF and HCl to obtain MXene, synthesizing platinum nano-particle modified MXene nano-enzyme (MXene (at) Pt) by using dopamine carbon dots and sodium borohydride as reducing agents and adopting an in-situ reduction technology, and detecting aflatoxin B1 in coffee by using the MXene (at) Pt nano-enzyme (MXene (at) Pt nano-enzyme (MXene (at) Pt nano-enzyme (MXene (at) Pt nano-enzyme (MXene (at) Pt). The MXene (at) Pt shows near-infrared light stimulation enhanced peroxidase-like activity and photo-thermal performance and can catalyze blue deepening and temperature rising of a substrate 3, 3 ', 5, 5'-tetramethyl benzidine (TMB), when aflatoxin B1 exists, POD-like activity of MXene (at) Pt nano-enzyme is inhibited, and colorimetric and temperature signals are reduced; a method for detecting the AFB1 by the colorimetric temperature dual-mode sensor is established, and the method has the characteristics of high sensitivity, strong specificity, simplicity and rapidness in operation and the like.

The invention discloses a graphene quantum dot material as well as a preparation method and application thereof, and belongs to the technical field of biomedical materials. The preparation method comprises the following steps: S1, carrying out hydrothermal reaction on a mixed solution of mesoporous SiO2 and a carbon source to obtain a product I; s2, the product I and a fluoride solution are mixed to remove SiO2, and a product II is obtained; and S3, refining the product II to obtain the graphene quantum dot material. The carbon source is selected from at least one of triammonium citrate, diammonium hydrogen citrate, citric acid, folic acid, urea, thiourea and dicyanodiamine; the fluoride is selected from ammonium bifluoride and / or hydrogen fluoride. The particle size of the graphene quantum dot material provided by the invention is 15-30nm, the distribution is controllable, and the raw materials are easy to obtain; the prepared platinum nanoparticle / graphene quantum dot composite nanomaterial is high in solubility, stable in physical and chemical properties and remarkable in chemotherapy effect.

The invention discloses a method for synthesizing a platinum-based nitrogen-doped graphdiyne catalyst based on an atomic layer deposition technology and application of the platinum-based nitrogen-doped graphdiyne catalyst. Firstly, hexabromobenzene and calcium carbide are subjected to vacuum ball milling, calcination and purification to obtain a graphdiyne carrier, then the graphdiyne carrier and melamine are mixed and calcined to achieve nitrogen doping of the carrier, and then loading of platinum nanoparticles is accurately controlled through an atomic layer deposition technology. According to the method, the characteristics of an atomic layer deposition technology are utilized, deposition parameters and the number of cycles are controlled, uniform distribution and size control of Pt nano-particles on porous graphdiyne are achieved, and a nitrogen-doped graphdiyne carrier and the platinum nano-particles have a synergistic effect. The platinum-based nitrogen-doped graphdiyne catalyst prepared by the invention has the specific surface area of 734.8 m < 2 > g < 1 > and the average pore size of 8.68 nm, and shows excellent electrocatalytic activity and dynamic performance in reaction.

The invention discloses a nano-enzyme-SERS (Surface Enhanced Raman Scattering) bifunctional sensor for detecting colorectal cancer markers with high sensitivity as well as a preparation method and application of the nano-enzyme-SERS bifunctional sensor. The preparation method comprises the following steps: coating a layer of platinum (Pt) on the surface of gold nanoparticles (AuNPs) by utilizing a chemical reduction method so as to form gold-platinum nanoparticles (Au (at) Pt NPs); assembling the synthesized Au (at) Pt NPs into an aminated capillary tube through electrostatic adsorption, so as to prepare a capillary tube SERS (Surface Enhanced Raman Scattering) substrate; the surface of Au (at) Pt NPs is modified with a marker aptamer through an Au-S bond, and the nano enzyme-SERS dual-function sensor is prepared. In the presence of hydrogen peroxide (H2O2), the Au (at) Pt NPs can catalyze the oxidation of 3, 3 ', 5, 5'-tetramethyl benzidine (TMB) to generate oxidized TMB (oxTMB) with a strong SERS (Surface Enhanced Raman Scattering) signal. When Hcy exists, the reductive sulfydryl of Hcy consumes hydroxyl free radicals (. OH) generated by H2O2 decomposition, so that TMB oxidation is inhibited, and SERS signal intensity is weakened. A linear regression equation of the logarithm of the Hcy concentration and the signal intensity is drawn according to the SERS signal intensity, so that quantitative detection of the Hcy is realized.

The invention discloses a quorum sensing inhibitor loaded nano composite material and a preparation method and application thereof, and belongs to the field of biomedical materials.The preparation method comprises the steps that MnO2 nano particles are dispersed in a polyallylamine hydrochloride aqueous solution, and a MnO2 / PAH compound is obtained; dispersing the MnO2 / PAH compound in a polyacrylic acid aqueous solution for secondary modification; the modified nano particles are mixed with a MgCl2 solution, ultrasonic treatment and aging treatment are carried out, and a MnO2-Mg compound is obtained; platinum nanoparticles grow in situ and are loaded on the surface of the MnO2-Mg compound by adopting a chemical reduction method to obtain MnO2-Mg / Pt; and loading the BBF on the MnO2-Mg / Pt to obtain the MnO2-Mg / Pt-coated BBF nano composite material. The invention aims to enhance the chemical kinetics efficiency and cooperate with the biomembrane inhibition effect to realize efficient treatment of periodontitis.

The invention discloses a tetracycline detection method based on defect PCN-224-Pt NPs with high oxidase activity, and belongs to the technical field of ecosystem and public health detection. The method comprises the following steps: firstly synthesizing PCN-224, then synthesizing PCN-224 (at) Pt NPs, and finally carrying out tetracycline colorimetric sensing detection. According to the invention, the PCN-224 (at) Pt NPs is synthesized by growing platinum nanoparticles (PtNPs) on the surface of a PCN-224 nanocube in situ. By introducing defect engineering into a metal structure of PCN-224, vacancy defects and active sites are formed, so that generation of small-particle-size and uniformly dispersed platinum nanoparticles is realized, the load rate of PtNPs in the PCN-224-Pt NPs nano-enzyme is remarkably improved, and the oxidase activity of the PCN-224-Pt NPs nano-enzyme is further enhanced. As the PCN-224 has a porphyrin metal structure, the PCN-224 shows excellent tetracycline adsorption capacity, active sites of platinum are effectively covered, and the catalytic activity of the PCN-224-Pt NPs nano-enzyme is inhibited. Experiments show that the limit of detection (LOD) of the method is 0.04 [mu] M.

The invention relates to the field of inorganic functional materials, and particularly discloses a corrosion-resistant layered Pt-C catalyst and a preparation method and application thereof. The nitrogen-doped carbon carrier, the spinel oxide and the Pt nanoparticles are arranged to form a novel corrosion-resistant catalyst, and through the synergistic effect of the spinel oxide AB2O4 and the nitrogen-doped carbon carrier N-Carbon, the electron cloud density on the surface of the carbon carrier is effectively reduced, the carbon corrosion problem of traditional Pt / C under high potential is inhibited, and the carrier stability is remarkably improved; spinel oxide is used as an anchoring point of platinum nanoparticles, the migration energy barrier of the platinum nanoparticles is improved, the platinum utilization rate is improved through an in-situ precipitation process, the comprehensive cost is reduced compared with commercial Pt / C, and due to the fact that the production process is simple and the production period is short, the production cost is reduced. The catalyst shows excellent oxygen reduction reaction catalytic activity and stability in zinc-air cells and fuel cells, the preparation method is simple, special equipment is not needed, and the catalyst has good industrial amplification potential.

The invention discloses a fuel cell dry membrane electrode and a preparation method thereof, a catalyst and an ionomer are mixed in an aqueous solution, in the directly used catalyst, platinum black particles and a carbon carrier are anchored through a surface functional group, platinum nanoparticles are good in dispersity, and in the aqueous solution, the platinum black particles and the carbon carrier are uniformly dispersed. The negative-SO3H group from the ionomer particles can attract the positively-charged Pt particles, so that the ionomer can uniformly cover the surfaces of the Pt particles, an ionomer / Pt particle interface is spontaneously formed, the ionomer can be uniformly distributed on metal active sites, on one hand, the transfer of protons to the active sites can be accelerated, the reaction kinetics can be improved, and on the other hand, the reaction efficiency can be improved; on the other hand, metal dissolution or poisoning is reduced, and membrane electrode performance and service life are improved. The use of toxic and expensive organic solvents is avoided, a more environment-friendly and lower-cost dry preparation process is adopted, proton membrane swelling in the preparation process is avoided, and the proton conductivity is improved.

The invention relates to the technical field of catalyst preparation, in particular to a neodymium-doped titanium dioxide loaded platinum nanoparticle composite catalyst as well as a preparation method and application thereof. The preparation method comprises the following steps: dissolving an organic titanium salt and a soluble neodymium salt in ethanol to obtain a mixed solution; mixing the ethanol dispersion liquid of the SiO2 spheres, the mixed solution and ammonia water, and carrying out hydrothermal reaction to obtain Nd-SiO2 (at) TiO2 core-shell spheres; etching SiO2 in the Nd-SiO2 (at) TiO2 core-shell sphere by adopting a sodium hydroxide solution to obtain a neodymium-doped titanium dioxide hollow sphere; and dropwise adding a sodium borohydride solution into an aqueous solution of the neodymium-doped titanium dioxide hollow spheres and a soluble platinum salt, and carrying out a reduction reaction to obtain the neodymium-doped titanium dioxide loaded platinum nanoparticle composite catalyst. The preparation method provided by the invention not only improves the photocatalytic efficiency and electro-catalytic reaction activity of the neodymium-doped titanium dioxide loaded platinum nanoparticle composite catalyst, but also enhances the long-term stability and durability of the neodymium-doped titanium dioxide loaded platinum nanoparticle composite catalyst.

The invention discloses an electrochemical luminescence immunosensor for detecting interleukin-1 beta as well as a preparation method and application of the electrochemical luminescence immunosensor. The electrochemical luminescence immunosensor comprises a three-electrode system consisting of a working electrode, a reference electrode and a counter electrode, the working electrode is a modified electrode of CoAl layered double hydroxides, the modified electrode is subjected to alkali etching and then loaded with platinum nanoparticles, then an interleukin-1 beta antibody is fixed, and non-specific sites are closed, so that the working electrode is obtained; when the immunosensor is used for detection, a solution containing luminol is used as an electrolyte. The working electrode of the immunosensor takes oxygen vacancy-rich CoAl layered double hydroxide as a substrate, platinum nanoparticles are combined to realize an EMSI effect, an electrochemical luminescence signal of a luminol-dissolved oxygen system is remarkably enhanced, and antigen-antibody specific recognition is combined to realize quantitative detection of IL-1beta. The method has the characteristics of strong anti-interference capability, high detection speed and good stability.

The preparation method mainly comprises the following steps: dissolving chloroplatinic acid, lanthanum salt and manganese salt in water according to a certain proportion, adding a complexing agent, adjusting the pH value, and carrying out gelation, drying and high-temperature calcination to obtain a perovskite precursor; and treating in a reducing atmosphere, so that platinum atoms are selectively dissolved out from crystal lattices, high-dispersion platinum nanoparticles are formed on the surface, and finally, the composite catalyst with extremely low platinum loading capacity is obtained. According to the method, platinum species are stably anchored through the perovskite carrier, the platinum atom utilization rate and catalytic stability are remarkably improved, excellent electrocatalytic activity and durability are shown in the oxygen reduction reaction, and the method can be widely applied to energy conversion equipment such as zinc-air cells and fuel cells and has important practical application value.

The present invention discloses a preparation method of a platinum-carbon catalyst, a platinum-carbon catalyst, and a catalyst coating film, comprising the following steps: step 1, adding a dispersing aid solution to a polyol solution of a platinum precursor, causing a coordination reaction, and obtaining a first material; step 2, adding a carbon carrier polyol slurry to the first material obtained in step 1, mixing, and obtaining a second material; step 3, heating the second material obtained in step 2 to 125° C. to 160° C., reacting for 1 h to 5 h, performing a reduction reaction, and cooling; then adding deionized water, continuing to stir for 1 h to 5 h, and obtaining a third material; step 4, concentrating the third material obtained in step 3, and then performing a dry grinding process to obtain a platinum-carbon catalyst. The method of the present invention avoids the introduction of other harmful impurities, does not require washing, has simple steps, and has low process costs; platinum nanoparticles can be evenly dispersed on the carbon carrier, have weak agglomeration, and the platinum-carbon catalyst has a high electrochemical active area and good stability.

The present invention relates to a platinum / tungsten trioxide / silicoaluminate composite, a preparation method thereof and an application thereof. In the present invention, a platinum colloid and a tungsten trioxide colloid are respectively prepared, and then the platinum colloid and the tungsten trioxide colloid are mixed and silicon aluminate is added thereto to obtain the platinum / tungsten trioxide / silicoaluminate composite. The preparation method is very simple, easy to repeat and control; in the platinum / tungsten trioxide / silicoaluminate composite prepared by the present invention, there is a good combination between platinum nanoparticles and tungsten trioxide nanoparticles. When used as a catalyst in the selective hydrogenolysis reaction of polyols, it has a higher polyol conversion rate and selectivity, and good repeatability.

The invention belongs to the technical field of catalysts, and provides a platinum nano oxygen reduction catalyst and a preparation method and application thereof.The preparation method of the platinum nano oxygen reduction catalyst comprises the following steps that an MOF derived carbon material is dispersed in a mixed solution of deionized water and ethyl alcohol, and a mixed solution is obtained; selecting a compound containing a platinum coordination unit with negative charge or positive charge according to positive and negative Zeta potential, stirring at room temperature, and fully adsorbing the two compounds by utilizing electrostatic acting force to obtain a reaction solution; and evaporating the reaction solution to dryness, and then carrying out a reduction reaction at 300-600 DEG C in a hydrogen reducing atmosphere to obtain the platinum nano oxygen reduction catalyst. The obtained catalyst is applied to a proton exchange membrane fuel cell, on one hand, the stability of platinum nanoparticles is improved through the micropore confinement effect, poisoning of perfluorosulfonic acid and other polymer electrolytes is avoided, on the other hand, pore channels are communicated, mass transfer is effectively enhanced, and the catalyst subjected to confinement shows excellent catalytic activity.

The invention provides a method for oxidatively synthesizing dihydronaphthalene-1 (2H)-ketone from styrene and derivatives thereof, which comprises the following steps: in an electrochemical catalytic reactor, oxidizing styrene and derivatives thereof into 3, 4-dihydronaphthalene-1 (2H)-ketone through electrochemical catalysis; a working electrode of the electrochemical catalytic reactor is a platinum nanoparticle electrode. The reaction does not need harsh temperature and pressure, does not use an additional redox agent, only utilizes the cleanest reaction reagent'electrons', generates the required catalyst or reaction active intermediate in situ, has the advantages of cheap and easily available electrode material, simple process and high repeatability, is an efficient, safe, green and environment-friendly production process, and is suitable for industrial production. The potential industrial application value is realized.

Disclosed herein is a method for producing a platinum (Pt) decorated single-layer transition metal dichalcogenide (TMD) composite. The method includes steps of, (a) mixing single-layer TMD nanosheets with a reducing agent, K2PtCl4, and water to form a mixture, wherein the reducing agent and the K2PtCl4 are present in a molar ratio of 3:2 in the mixture; and (b) irradiating the mixture of step (a) for about 0.1-2 hrs to allow the growth of Pt nanoparticles on the single-layer TMD nanosheets thereby forming the Pt decorated single-layer TMD composite. Also disclosed herein is a method of producing hydrogen from an aqueous solution. The method includes electrolyzing the aqueous solution in an electrochemical cell characterizing in having an electrode made from the present Pt decorated single-layer TMD composite.

The invention discloses a preparation method and application of a gold-platinum-iron flower-shaped nano composite material with cascade catalytic capacity, and relates to the technical field of tumor hunger therapy, chemical power therapy and near-infrared photothermal therapy. According to the preparation method of the gold-platinum-iron flower-shaped nano composite material with the cascade catalytic capability, the flower-shaped zeolite imidazole framework is further modified and pyrolyzed, and the iron element is anchored on the carbon framework in a monatomic state; gold-platinum nanoparticles and hyaluronic acid which are tightly combined and grow in situ are further loaded on the surface of the nano-material, so that the nano-material has good biocompatibility and targeting property and can be used as a nano-composite material for tumor chemotherapy and near-infrared photothermal therapy. According to the invention, the variety of nano composite materials for tumor targeted hunger therapy, chemotherapy and near-infrared photothermal therapy by taking a zeolite-like imidazole skeleton as a substrate is enriched. The invention can obtain the preparation method and application of the gold-platinum-iron flower-shaped nano composite material with the cascade catalytic capability.

The invention discloses a dysprosium-doped platinum-based catalyst and a preparation method and application thereof, and belongs to the technical field of battery materials.The preparation method of the dysprosium-doped platinum-based catalyst comprises the following steps that a dysprosium-containing carbon carrier is placed in a first solvent to be subjected to ultrasonic dispersion, and turbid liquid is obtained; adding a soluble platinum salt and a soluble transition metal salt into the turbid liquid, and mixing to obtain a mixed liquid; removing the first solvent in the mixed solution to obtain a solid product; and calcining and etching the solid product to obtain the dysprosium-doped platinum-based catalyst. The dysprosium-containing carbon carrier is adopted to load the platinum-based intermetallic compound, so that dysprosium and the platinum-based nanoparticles can realize relatively strong association and generate interaction among electrons, atom diffusion is further promoted, the crystallinity is improved, and the electronic structure of the platinum nanoparticles is favorably adjusted. The dysprosium-doped platinum-based catalyst is relatively high in internal order degree, and has relatively high activity and stability when being applied to an acidic ORR reaction.

This invention relates to the field of chemical hydrogen storage, and discloses a carbon-based catalyst, its preparation method and application, and a method for the dehydrogenation of methylcyclohexane. The catalyst comprises nitrogen (N), carbon (C), hydrogen (H), and platinum nanoparticles; the catalyst has the following properties: "Pt x C y N z H a The schematic chemical composition of the catalyst is shown in the figure, where z:a = 1.5~5; z:x = 5~50; z:y < 0.016; in the catalyst, nitrogen atoms are covalently bonded to at least two carbon atoms; nitrogen atoms are covalently bonded to hydrogen atoms; the carbon tetrachloride adsorption value (CTC) of the catalyst is ≥80%; in the XRD spectrum of the catalyst, the A of the Pt(111), (200), (220), (222) crystal plane diffraction peaks of the platinum nanoparticles is ≥85%, and A = (Pt(111) peak area) / (peak area of ​​Pt(111) + peak area of ​​Pt(200) + peak area of ​​Pt(220) + peak area of ​​Pt(222))) × 100%. This catalyst has good catalytic activity and low hydrogenolysis activity, making it particularly suitable for dehydrogenation reactions, such as the dehydrogenation reaction of alkyl-substituted cycloalkanes. It can effectively control the hydrogenolysis reaction during the dehydrogenation process and reduce the generation of by-products. It is especially suitable for the application of methylcyclohexane dehydrogenation reaction. After the dehydrogenation reaction, the conversion rate of methylcyclohexane is high, and the methane content in the product is <0.3wt%.

The invention provides a diagnosis and treatment integrated nano platform as well as a preparation method and application thereof. According to the diagnosis and treatment integrated nano platform, an organic-inorganic nano hybrid is constructed through structure optimization and function integration, four modes of PTT, PDT, SDT and CDT are organically combined innovatively, and efficient synergistic treatment of GBM is achieved through real-time monitoring of photoacoustic imaging. First, a dOMV encapsulation strategy significantly improves the ability to penetrate through the blood brain barrier. Meanwhile, the IEICO-4F has a strong near-infrared absorption characteristic and has a synergistic effect with the high catalytic activity of the mesoporous platinum nanoparticles. Under the laser / ultrasonic excitation condition, the diagnosis and treatment integrated nano platform shows excellent photo-thermal conversion performance, the Fenton reaction rate can be increased, endogenous hydrogen peroxide can be continuously catalyzed to be decomposed to generate oxygen, and the tumor hypoxia state is effectively relieved. The series of reactions further enhance the generation of ROS, activate a Caspase-1 / GSDMD mediated pyroptosis pathway, finally achieve an efficient tumor inhibition effect, and successfully break through the limitation of a single treatment mode.

The invention discloses a preparation method of polyether modified silicone oil, 4-dimethylaminopyridine (DMAP) is adopted, nitrogen atoms in the 4-dimethylaminopyridine (DMAP) have strong coordination ability and form a stable Pt-DMAP complex with a platinum precursor, aggregation of platinum ions on the surface of a carrier is inhibited, high-dispersion platinum nanoparticles are formed, the platinum loading capacity is improved, the active site density is increased, and the polyether modified silicone oil is prepared. Tetraethyl orthosilicate is adopted and added and is subjected to hydrolytic condensation under the catalysis of DMAP, and a silicon dioxide network is formed inside and around the ionic liquid. The SiO2 network physically confines the platinum nanoparticles and the ionic liquid in pore channels or structures of the SiO2 network, leaching and loss of active components (Pt and the ionic liquid) are greatly prevented, the SiO2 network provides skeleton support for the catalyst, the mechanical strength and stability of the catalyst are improved, and the catalyst can tolerate centrifugation and washing and be recycled for multiple times. And finally, a supported solid catalyst, instead of a heterogeneous solution, is formed, so that the separation and recovery through filtration are greatly facilitated.

This invention belongs to the field of biosensing technology, specifically relating to a modified carbon fiber electrode for detecting dopamine, its preparation method, and its application. The modified carbon fiber electrode comprises a carbon fiber electrode onto which gold-platinum bimetallic nanoparticles and polydopamine are sequentially modified. The preparation method specifically includes: firstly, modifying the surface of activated carbon fiber filaments with chloroauric acid and sodium citrate to obtain Au@CF; then, modifying the Au@CF surface with ascorbic acid and chloroplatinic acid to obtain platinum nanoparticles, obtaining Au / Pt@CF; finally, immersing the Au / Pt@CF in a dopamine solution to coat the Au / Pt@CF surface with polydopamine, obtaining PDA@Au / Pt@CF. This electrode has advantages such as high sensitivity, low detection limit, strong anti-interference ability, good biocompatibility, and high mechanical stability, making it suitable for dynamic monitoring of dopamine in the living brain.

A nanocatalyst includes platinum nanoparticles and base transition metal oxide clusters, wherein each base transition metal oxide cluster is enclosed by a platinum shell.

The invention relates to a sulfhydrylated platinum nanoparticle, the surface of a metal platinum nanoparticle is modified and grafted with a sulfydryl polymer, and free sulfydryl on the surface of the sulfhydrylated platinum nanoparticle helps the nanoparticle to stay at a tumor site for a long time, so that the nanoparticle is convenient to cooperate with sensitization radiotherapy in a radiotherapy period, and the sensitization effect of the metal platinum in the tumor radiotherapy process is maximized; and the preparation method of the platinum thiolate nanoparticles is simple, and the platinum thiolate nanoparticles have obvious effects of retention in tumors and tumor radiotherapy sensitization, and have good application prospects.

The present invention belongs to the technical field of catalysts, and relates to a highly active platinum-carbon catalyst, a preparation method thereof, and an application thereof in catalytic purification of formaldehyde. The present invention discloses a highly active platinum-carbon catalyst, which has a core-shell structure. It uses porous metal-modified and pore-expanded activated carbon M-AC as the core, deposits a TiO₂ nano-layer on the surface of the core, and loads Pt@TiO₂ on the surface of the TiO₂ nano-layer; the metal M in the porous metal-modified and pore-expanded activated carbon M-AC is one or two of alkali metals K and Na; part of the TiO₂ nano-layer on the surface of the porous metal-modified and pore-expanded activated carbon M-AC migrates to the surface of platinum nanoparticles to form Pt@TiO₂. The present invention also discloses that the highly active platinum-carbon catalyst has a good catalytic purification effect on formaldehyde.