Preparation method of medical polylactic acid modified calcium phosphate bone cement composite 3D printing material

Abstract

The invention relates to the technical field of 3D printing materials, in particular to a preparation method of a medical polylactic acid modified calcium phosphate bone cement composite 3D printing material. The preparation method of the medical polylactic acid modified calcium phosphate bone cement composite 3D printing material comprises steps as follows: S1, preparation of modified hectorite;S2, preparation of rare earth modified calcium phosphate powder; S3, preparation of the medical polylactic acid modified calcium phosphate bone cement composite 3D printing material. The composite obtained with the preparation method of the medical polylactic acid modified calcium phosphate bone cement composite 3D printing material has excellent printing performance and outstanding application performance, has the advantages of excellent mechanical strength, mechanical performance and compressive strength and has the mechanical strength of inorganic calcium phosphate materials and flexibilityof polymer polylactic acid materials, and besides, the preparation process is simpler and lower in production cost.

Description

technical field [0001] The invention relates to the technical field of 3D printing materials, in particular to a method for preparing medical polylactic acid modified calcium phosphate bone cement composite 3D printing materials. Background technique [0002] Calcium phosphate cement (Calcium phosphate cement, CPC) has good biocompatibility and injectability, and can be shaped into various shapes under physiological conditions. The weakly crystalline hydroxyapatite and The inorganic composition of human bone tissue is similar, and it is a new type of biomedical material with broad application prospects. The emergence of 3D printing technology provides a new method for the design, manufacture and optimization of various shapes of bone tissue structures. Because 3D printing technology can print any shape of bone tissue structure, calcium phosphate bone cement is used as printing material to print various artificial bone materials through 3D printing technology, which has been...

AI Technical Summary

Problems solved by technology

However, at present, China does not have any ability to independently produce calcium phosphate bone cement printing materials for 3D printing, and completely relies on imports, so a large amount of precious foreign exchange is consumed in this area every year

[0003] Although it has been widely used clinically as a repair material for bone tissue, there are still some problems with CPC, the most important of which is that CPC has poor mechanical properties and low compressive strength, which cannot meet the mechanical strength requirements of human bone tissue. It cannot be effectively used as a bone filling material for load-bearing parts, which leads to certain restrictions on the application of CPC, especially in the tissue engineering industry.