High strength suture coated with collagen

a high-strength, collagen-based technology, applied in the direction of coatings, braids, surgery, etc., can solve the problems of not having acceptable knot tie down characteristics for surgical applications, and achieve the effect of improving tie down characteristics, high strength, and improving tie down properties

Inactive Publication Date: 2008-02-28
UNIV OF CONNECTICUT
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  • Abstract
  • Description
  • Claims
  • Application Information

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Benefits of technology

[0006]The present invention advantageously provides a high strength surgical suture material with improved tie down characteristics. The suture features a braided jacket made of ultrahigh molecular weight fibers coated with collagen. The ultrahigh molecular weight polyethylene provides strength. Polyester fibers woven with the high molecular weight polyethylene provide improved tie down properties. Collagen coating is provided to stimulate proliferation and protein synthesis more than standard sutures, and therefore may aid in the tendon-to-bone incorporation process. Moreover, collagen, in addition to providing structural support, can interact with other matrix proteins and cellular receptor affecting cell behavior and gene expression.

Problems solved by technology

This material is much stronger than ordinary surgical suture, however, it does not have acceptable knot tie down characteristics for use in surgical applications.

Method used

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  • High strength suture coated with collagen
  • High strength suture coated with collagen
  • High strength suture coated with collagen

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USP Size 5 (EP size 7)

[0025]Made on a 16 carrier Hobourns machine, the yarns used in the braided jacket are Honeywell Spectra 2000, polyester type 712, and nylon. The jacket is formed using eight strands of 144 decitex Spectra per carrier, braided with six strands of 100 decitex polyester, and two strands of tinted nylon. The core is formed of three carriers of 144 decitex Spectra braided at three to six twists per inch. A No. 5 suture is produced.

[0026]To make various sizes of the inventive suture, different decitex values and different PPI settings can be used to achieve the required size and strength needed. In addition, smaller sizes may require manufacture on 12 carrier machines, for example. The very smallest sizes can be made without a core. Overall, the suture may range from 5% to 90% ultrahigh molecular weight polymer (preferably at least 40% of the fibers are ultrahigh molecular weight polymer), with the balance formed of polyester and / or nylon. The core preferably compris...

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Abstract

A high strength surgical suture formed of ultrahigh molecular weight polyethylene (UHMWPE) yarns, the suture being coated with native or denatured collagen. The braided jacket surrounds a core formed of twisted yarns of ultrahigh molecular weight polyethylene. The suture has exceptional strength, is ideally suited for most orthopedic procedures, and can be attached to a suture anchor or a curved needle.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS[0001]This application claims priority to U.S. Provisional Application No. 60 / 840,466, filed on Aug. 28, 2006, the entire disclosure of which is hereby incorporated by reference.BACKGROUND OF THE INVENTION[0002]1. Field of the Invention[0003]The present invention relates to high strength surgical suture materials, and more particularly to braided suture blends of ultrahigh molecular weight polyethylene having bioabsorbable coatings.[0004]2. Description of the Related Art[0005]Suture strength is an important consideration in any surgical suture material. One of the strongest materials currently formed into elongated strands is an ultrahigh molecular weight long chain polyethylene, typically used for fishing line and the like, which is sold under the trade names Dyneema or Spectra. This material is much stronger than ordinary surgical suture, however, it does not have acceptable knot tie down characteristics for use in surgical applications.BRIEF...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61B17/06A61B17/04
CPCA61L17/04A61L17/145C08L23/06C08L2203/12B05D1/18D04C1/02D10B2509/04
Inventor MAZZOCCA, AUGUSTUS D.MCCARTHY, MARYBETH
Owner UNIV OF CONNECTICUT
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