Biodegradable nanocomposites with enhance mechanical properties for soft tissue

a biodegradable and soft tissue technology, applied in the direction of synthetic polymeric active ingredients, organic active ingredients, prosthesis, etc., can solve the problems of non-biodegradable components, biocompatible, biodegradable nanoparticles to strengthen matrices intended for in vivo use,
US20070071790A1Inactive Publication Date: 2007-03-29NORTHWESTERN UNIV
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Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
NORTHWESTERN UNIV
Publication Date
2007-03-29
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention is directed to a novel poly(diol citrates)-based nanocomposite materials created using completely biodegradable and biocompatible polymers that may be used in tissue engineering. More specifically, the specification describes methods and compositions for making and using nanocomposites comprised of citric acid copolymers and polymers including but not limited to poly(L-lactic acid) (PLLA) and poly(lactic-co-glycolic acid) (PLGA).
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Description

[0001] The present application claims the benefit of priority of U.S. Provisional Application No. 60 / 721,687 which was filed Sep. 28, 2005. The entire text of the aforementioned application is incorporated herein by reference.FIELD OF THE INVENTION

[0002] The present invention is generally directed to a substrate used for tissue engineering. The substrate is a biodegradable elastomeric polymer. Methods and compositions for testing and using the same are disclosed. BACKGROUND

[0003] The need for biodegradable polymers in emerging technologies such as tissue engineering, drug delivery, and gene therapy has been fueling a quest for novel biodegradable polymers [13-16]. In particular, biodegradable polymers with elastomeric properties have recently received attention for their potential use in the engineering of soft tissues such as blood vessel, heart valves, cartilage, tendon, and bladder, which exhibit elastic properties. Due to their long history of use in clinical applications, pol...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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