21 results about "Superior vena caval" patented technology

Tricuspid valve repair devices and associated systems and methods are disclosed herein. A tricuspid valve repair device configured in accordance with embodiments of the present technology can include, for example, a coaptation member configured to be positioned between one or more native leaflets of the tricuspid valve to at least partially fill a space between the native leaflets. The tricuspid valve repair device can further include one or more fixation mechanisms for securing the coaptation member in position between the leaflets. The fixation mechanisms can include clip mechanisms, lock mechanisms, stabilization members, anchors, and / or other structures configured to engage cardiac anatomy local to or remote from the tricuspid valve, such as the native leaflets, the tricuspid valve annulus, the right ventricular outflow tract, the superior vena cava, the inferior vena cava, and so on.

Prosthetic heart valves may be delivered to a targeted native heart valve site via one or more delivery catheters. In some embodiments, the prosthetic heart valve includes structural features that securely anchor the prosthetic heart valve to the anatomy at the site of the native heart valve. Such structural features can provide robust migration resistance. In addition, the prosthetic heart valves can include structural features that improve sealing between the prosthetic valve and native valve anatomy to mitigate paravalvular leakage. In particular implementations, the prosthetic heart valves occupy a small delivery profile, thereby facilitating a smaller delivery catheter system for advancement to the heart. Some delivery catheter systems can include a curved inner catheter to facilitate deployment of the prosthetic heart valve to a native tricuspid valve site via a superior vena cava or inferior vena cava.

The present invention discloses a PICC catheter positioning and identification device that combines ultrasound guidance with electrocardiogram signal monitoring. The device belongs to the field of image processing and includes: an ultrasound probe for acquiring ultrasound images of blood vessels and PICC catheters during PICC catheterization; electrocardiogram electrodes for acquiring the user's electrocardiogram signals; a signal acquisition and processing unit for acquiring and processing ultrasound images and electrocardiogram signals; an image fusion display unit connected to the signal acquisition and processing unit for fusing the processed ultrasound image with the electrocardiogram waveform on the same screen to obtain fusion display information; a position recognition and alarm unit for analyzing and identifying the real-time position of the PICC catheter based on the fusion display information, and issuing an alarm when it is detected that the PICC catheter has reached the optimal position of the superior vena cava. By integrating ultrasound guidance and electrocardiogram signal monitoring into one device, a technical effect is achieved that helps nurses more accurately and quickly identify whether the PICC catheter has reached the optimal position of the superior vena cava.

The invention relates to anchor channels and subannular anchors for a transcatheter heart valve replacement, and in particular for an orthogonally delivered transcatheter prosthetic heart valve having a annular support frame having compressible wire cells that facilitate rolling and folding the valve length-wise, or orthogonally to the central axis of the flow control component, allowing a very large diameter valve to be delivered and deployed to the tricuspid valve from the inferior vena cava or superior vena cava, or trans-atrially to the mitral valve, the valve having a height of about 5-60 mm and a diameter of about 25-80 mm, without requiring an oversized diameter catheter and without requiring delivery and deployment from a catheter at an acute angle of approach.

A method for performing a robotic-assisted orthotopic heart transplant includes forming a working port subareolarly by a mini-thoracotomy at a working intercostal space, forming additional ports for robotic arms, and arranging robotic arms through the ports. A first robotic arm with first forceps extends through a second port lateral to a mid-clavicular line, while second and third robotic arms containing an imaging device and second forceps operate through the working port. A fourth robotic arm with scissors or needle holder extends through a third port proximal to an anterior axillary line. The method includes cannulating for cardiopulmonary bypass, opening the pericardium, cross-clamping the aorta, removing the native heart, and performing sequential anastomoses of the donor heart including the left atrium, pulmonary artery, aorta, inferior vena cava, and superior vena cava.

Prosthetic heart valves may be delivered to a targeted native heart valve site via one or more delivery catheters. In some embodiments, the prosthetic heart valve includes structural features that securely anchor the prosthetic heart valve to the anatomy at the site of the native heart valve. Such structural features can provide robust migration resistance. In addition, the prosthetic heart valves can include structural features that improve sealing between the prosthetic valve and native valve anatomy to mitigate paravalvular leakage. In particular implementations, the prosthetic heart valves occupy a small delivery profile, thereby facilitating a smaller delivery catheter system for advancement to the heart. Some delivery catheter systems can include a curved inner catheter to facilitate deployment of the prosthetic heart valve to a native tricuspid valve site via a superior vena cava or inferior vena cava.

The invention relates to a tricuspid regurgitation control device for an orthogonal transcatheter heart valve prosthesis. The invention also relates to access and occluder devices, in particular heart valve regurgitation drums and optionally closure discs and / or tubular stents, for managing and providing intentional regurgitation levels within transcatheter heart valve substitutes and in particular orthogonally delivered transcatheter prosthetic heart valves, an orthogonal delivery transcatheter prosthetic heart valve has a first inner flow control member / valve, a second inner reflux control member, and an outer annular support frame with a compressible wire unit that facilitates flat folding along the z-axis and compression of the valve vertically along the y-axis or orthogonal to the central axis of the flow control member, the present invention relates to a valvular delivery and deployment system, in particular to a valvular delivery and deployment system, which allows delivery and deployment of very large diameter valves from the inferior or superior vena cava to the tricuspid valve or trans-atrial delivery and deployment to the mitral valve, the valves having a height of about 5-60 mm and a diameter of about 25-80 mm, without extra-large diameter catheters and without delivery and deployment from catheters at acute access angles.

Embodiments herein provide a Pulmonary Circulation Assist Implant for passively regulating the cardiovascular blood flow in a subject born with a univentricular heart. The Pulmonary Circulation Assist Implant is configured to avoid a head-on collision between the bloodstreams from a Superior Vena Cava (SVC) and an Inferior Vena Cava (IVC) without an offset between them. Further, the Pulmonary Circulation Assist Implant is configured to smoothly distribute the SVC blood and IVC hepatic blood to both lungs in equal proportions without swirling. Also, the Pulmonary Circulation Assist Implant is configured to avoid the occurrence of retrograde flow and reduce power loss.

Blood flow affecting implant and implantation thereof in superior vena cava, optionally including disintegration of endothelium layer and inducing tissue ingrowth within implant. Implant includes elongated body with optional tubular inner layer forming orifice, shapeable to final orifice diameter for restricting blood flowing therethrough to chosen average flow rate; and / or tubular outer layer provided coaxially around inner layer. Outer layer is formed of second material provided in elastically deformable state for facilitating elastic radial self-expanding from collapsed diameter up to relaxed maximal expanded diameter greater than diameter of inner wall portion of superior vena cava. Inner layer is formed of first material, in plastically or elastically deformable state.

This invention discloses a method and system for estimating the insertion length of infusion port catheters based on medical image recognition, specifically relating to the field of medical information processing. It addresses the problem of periodic tip drift during existing infusion port catheter insertion. The method includes: acquiring enhanced CT image sequences covering the superior vena cava to the posterior wall of the atrium; extracting continuous edge attenuation regions; constructing a set of frame-level fuzzy boundary contour curves; performing phase calibration on the image frames using cardiac cycle signals; generating phase-stable contour clusters through phase clustering; and interpolating and fitting the contour point trajectories to generate a fuzzy domain deformation envelope map reflecting the maximum deformation range of the boundary. Further, the drift trajectory of the catheter tip within the envelope map is extracted, a tip drift path cluster is constructed, high-frequency clustering regions are identified through spatial density estimation, stable intervals are determined, and the extension length range of each path within the interval is calculated, outputting the effective insertion length range of the catheter.

The invention provides systems and methods for selectively occluding the superior vena cava to treat cardiac conditions. Systems and methods are provided for treating a condition, such as heart failure and / or pulmonary arterial hypertension, by at least partially occluding flow through the superior vena cava for an interval across multiple heart cycles. A catheter having an occlusion device is provided, as well as a controller that actuates a drive mechanism to provide at least partially occlude the superior vena cava of a patient, which reduces heart filling pressure and induces advantageous displacement of the patient's Frank-Starling curve towards healthy cardiac functionality and improved cardiac performance. The system may include a sensor to determine a degree of occlusion of the superior vena cava. The occlusion system may be used to reduce heart volume and facilitate cardiac surgery. A plugging system may be used to mitigate overloaded chambers during and / or after deployment of the VAD.

Tricuspid valve repair devices and associated systems and methods are disclosed herein. A tricuspid valve repair device configured in accordance with embodiments of the present technology can include, for example, a coaptation member configured to be positioned between one or more native leaflets of the tricuspid valve to at least partially fill a space between the native leaflets. The tricuspid valve repair device can further include one or more fixation mechanisms for securing the coaptation member in position between the leaflets. The fixation mechanisms can include clip mechanisms, lock mechanisms, stabilization members, anchors, and / or other structures configured to engage cardiac anatomy local to or remote from the tricuspid valve, such as the native leaflets, the tricuspid valve annulus, the right ventricular outflow tract, the superior vena cava, the inferior vena cava, and so on.

Prosthetic heart valves may be delivered to a targeted native heart valve site via one or more delivery catheters. In some embodiments, the prosthetic heart valve includes structural features that securely anchor the prosthetic heart valve to the anatomy at the site of the native heart valve. Such structural features can provide robust migration resistance. In addition, the prosthetic heart valves can include structural features that improve sealing between the prosthetic valve and native valve anatomy to mitigate paravalvular leakage. In particular implementations, the prosthetic heart valves occupy a small delivery profile, thereby facilitating a smaller delivery catheter system for advancement to the heart. Some delivery catheter systems can include a curved inner catheter to facilitate deployment of the prosthetic heart valve to a native tricuspid valve site via a superior vena cava or inferior vena cava.

This invention discloses a systemic circulation venous simulation system, comprising a right ventricular simulation component, an arterial compliance simulation component, a venous vessel module, a damping module, a throttling valve, a collapsible venous segment, a venous compliance simulation component, a right atrial simulation component, a drive module, and a data acquisition module. The right ventricular simulation component simulates the pumping function of the right ventricle; the arterial compliance simulation component simulates the elastic energy storage characteristics of the arterial system; the venous vessel module includes a collecting chamber, a superior vena cava return vessel, an inferior vena cava return vessel, and a vena cava confluence conduit; the collapsible venous segment prevents excessive negative pressure in the venous system; the venous compliance simulation component reduces the impact of right atrial pressure fluctuations on the venous vessels; and the right atrial simulation component simulates the right atrial filling state through internal volume changes. This simulation system can be used for in vitro testing of vena cava intervention devices.

The invention relates to the technical field of heart interventional operations, and discloses an interventional heart valve conveying system with a positioning function, which comprises a working assembly, a control assembly, a support assembly, a positioning assembly, a positioning assembly and a positioning assembly, the working assembly comprises a main sleeve and further comprises a positioning air bag fixedly connected to the main sleeve, a friction ring fixedly connected to the positioning air bag and an internal thread formed in the end of the main sleeve. The positioning air bag on the main sleeve is expanded and unfolded near the junction of the superior vena cava and the right atrium, coarse positioning of the main sleeve is completed, fine positioning is conducted through threaded connection of the internal thread on the main sleeve and the external thread on the adjusting end shell, the advancing process of the communication pipe is more accurate, the error possibility is reduced, and the communication pipe is more accurate in positioning. Meanwhile, clear image display is provided for the operation process through the general lens and the short-focus lens, the operation risk and the operation difficulty are further reduced, and the system is more beneficial to doctors lacking experience.

Cardiac load modulation systems and methods are disclosed for treatment of patients in congestive heart failure. Disclosed systems include dual occlusion, telescoping catheters allowing simultaneous or sequential occlusion in the superior vena cava and inferior vena cava to synergistically modulate heart pre-load on the right side of the heart and pressure difference in the kidneys as a potential treatment or management of acute decompensated heart failure (ADHF). Control algorithms and safety parameters for treatment with disclosed systems are also disclosed.

The invention relates to the technical field of biology, in particular to a mouse liver cell extraction and cryopreservation method. Comprising the following steps: performing liver perfusion and digestion: performing inferior vena cava intubation on a mouse corpse, cutting open vena cava, clamping superior vena cava, performing perfusion with perfusate for 6-8 minutes, and performing circulating perfusion with digestive juice for 10-15 minutes; separating and purifying the cells: taking out the liver, tearing a liver membrane in precooling termination digestion liquid at 3-5 DEG C, filtering by a screen, collecting filtrate, performing primary centrifugation on the filtrate, supplementing a complete culture medium, then performing secondary centrifugation, collecting cell precipitates, washing with the complete culture medium for 2-3 times, performing centrifugation again, and retaining the cell precipitates at the bottom to obtain purified parenchymal liver cells; and resuspending the purified parenchymal hepatic cells by using a precooled cryopreservation solution until the final concentration is (1-2) * 10 < 7 > cells / mL, sub-packaging and cryopreserving. The method is stable in operation, high in cell obtaining rate, good in activity and high in recovery rate after cryopreservation.

The invention discloses an infusion port catheter implantation length estimation method and system based on medical image recognition, particularly relates to the field of medical information processing, and is used for solving the problem of tip periodic drifting when an existing infusion port catheter is implanted. A continuous edge attenuation area is extracted, and a frame-level fuzzy boundary contour curve set is constructed; and performing phase calibration on the image frame in combination with a heart cycle signal, generating a phase stable contour cluster through phase clustering, and performing interpolation fitting on a contour point trajectory to generate a fuzzy domain deformation envelope diagram reflecting the maximum deformation range of the boundary. And further extracting a drift trajectory of the tip of the catheter in the envelope diagram, constructing a tip drift path cluster, identifying a high-frequency aggregation region through spatial density estimation, determining a stable interval band, calculating an extension length range of each path in the interval, and outputting an effective implantation length interval of the catheter.

The application provides a ventricular assist device, a control unit thereof and a medical device. The ventricular assist device comprises a first pumping device arranged at a proximal end of a flow conduit tube and a second pumping device arranged at a distal end of the flow conduit tube. The control unit first starts the first pumping device arranged in the superior vena cava or the inferior vena cava of a target user to perform pumping, so that a fluid inlet is arranged in the superior vena cava or the inferior vena cava, suction is reduced, and damage to ventricular tissue or destruction to a valve is avoided. When the current operation state of the first pumping device does not meet the demand of the target user, i.e., the target pressure is greater than a first threshold value, the second pumping device is started to increase the fluid pressure in the flow conduit tube, accelerate the pumping of blood from the fluid inlet to a fluid outlet, and thus improve the pumping efficiency of the ventricular assist device.

To provide a vascular anastomosis device capable of appropriately mixing blood of the vena cava superior and of the vena cava inferior.SOLUTION: A vascular anastomosis device (10) has: a first inlet pipe (1) anastomosed by the vena cava superior; a second inlet pipe (2) anastomosed by the vena cava inferior; a mixing chamber (5) which is connected to the first inlet pipe and the second inlet pipe, has an inner width larger than an inner diameter of the first inlet pipe and an inner diameter of the second inlet pipe, and has an inner wall recessed inward; and a first outlet pipe (3) and a second outlet pipe (4) connected to the mixing chamber.SELECTED DRAWING: Figure 1

A self-expandable stent has a dry valve made of bovine pericardium arranged at a proximal end thereof, a skirt surrounding the dry valve at the proximal end of the stent and made of one of bovine pericardium and polyester. The dry valve is configured to be rehydrated when placed in contact with a solution, and the stent includes eyelets arranged at the proximal end of the stent for fixing the stent at a point of interest, with the point of interest being one of the vena cava superior and the vena cava inferior.