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43 results about "Kaempferide" patented technology

Kaempferide is an O-methylated flavonol, a type of chemical compound. It can be found in Kaempferia galanga (aromatic ginger). It has been noted to inhibit pancreatic cancer growth by blockading an EGFR-related pathway.

Method for preparing sensor for detecting kaempferide molecular imprinting

The invention discloses a method for preparing a sensor for detecting kaempferide molecular imprinting. The method is characterized in that first chloroauric acid and graphene oxide to modify a glassy carbon electrode, and obtaining a nanogold graphene-modified glassy carbon electrode; adding 44-50% of ethanol, 10-14% of ethylene glycol dimethacrylate, 5-8% of styrene, 30-35% of 1-vinyl-3-butyl hexafluorophosphate, 1.0-2.0% of azodiisobutyronitrile and 2.0-5.0% of kaemperfol into a reactor, performing mixing and dissolution, perform stirring reaction for 28-30 h at 55+ / -2 DEG C, adopting methanol : acetic acid mixed solution to remove template molecules to obtain kaempferide molecularly imprinted polymer; dispensing the molecularly imprinted polymer to the nanogold graphene-modified glassy carbon electrode, and obtaining the kaempferide molecular imprinting sensor. The sensor is high in compatibility and selectivity. The sensor is high in sensitivity and good in specificity, has quickness in detection and can be reused.
Owner:UNIV OF JINAN

Method for extracting flavones ingredient and kaempferol from sophora fruit

The invention discloses a method for extracting flavone ingredients and extracting kaempferide from sophoricoside and relates to the medicine. The method comprises the following steps: de-ionized water is added into the raw material of the sophoricoside, and reflux extracting is carried out in heating condition; extracting liquid-purpose diatomite and filtering is carried out; the filter solution is put on a macroporous resin column, impurity is washed by water and the filter solution is eluted by high-concentration ethanol; concentrating and drying is carried out on the eluting solution, thus obtaining the sophoricoside flavone extract; hydrolysate is added into the sophoricoside flavone extract and hydrolyzing is carried out in heating condition; pH value is adjusted to neutral after hydrolysis; steaming and removing alcohol, filtering, washing repeatedly by water are carried out on filter residue; drying and extracting are carried out on the filter residue by an extracting agent of mixed solution of aether and ethanol, the extract solution is steamed and the high-purity kaempferide is obtained. The method can be used for producing high-purity kaempferide flavone extract and kaempferide and has the advantages of simple process, good product quality, high degree of comprehensive utilization, being suitable for industrial production and low cost.
Owner:GUIZHOU UNIV

Method for near-infrared online monitoring content change of total flavonol glycosides in folium ginkgo extraction process

InactiveCN104535524AReal-time monitoring of changes in total flavonol glycosides contentReliable resultsMaterial analysis by optical meansGlycoside formationGinkgo biloba
The invention discloses a method for near-infrared online monitoring content change of total flavonol glycosides in a folium ginkgo extraction process. The method comprises the following steps: associating data of a quercetin content, a kaempferide content and an isorhamnetin content measured by high performance liquid chromatography with near infrared spectral information by using a partial least squares method, and establishing a multivariate quantitative calibration model of the quercetin content, the kaempferide content and the isorhamnetin content in the folium ginkgo extraction process; quickly detecting the quercetin content, the kaempferide content and the isorhamnetin content in the unknown folium ginkgo extraction process by using the established multivariate quantitative calibration model. The method disclosed by the invention can be used for sampling an extracting solution in the folium ginkgo extraction process in real time and monitoring the content change of total flavonol glycosides in the folium ginkgo extracting solution in real time; the result is accurate and reliable.
Owner:NINGBO LIWAH PLANT EXTRACTION TECH

Method for transforming gingko pollen flavonoid glycoside employing microorganisms

The invention discloses a method for transforming gingko pollen flavonoid glycoside employing microorganisms. By adopting the method, the gingko pollen flavonoid glycoside is transformed by using lactobacillus BL1. The bacterial strain is facultative anaerobic, simple in cultivation condition, quick to grow, strong in fertility, safe and efficient, can generate a plurality of complex enzymes, and can carry out growth and propagation by taking single gingko pollen as matrix. The gingko pollen does not need wall-breaking treatment in advance; the flavonoid glycoside in the gingko pollen does not need complicated extraction and purification, and is efficiently transformed into corresponding aglycone; the capability of directly taking the gingko pollen as the raw material to transform the flavonoid glycoside into corresponding aglycone is high. The conversion ratio of flavonoid glycoside kaempferide-3,4'-diosgenin-diglucoside, 3-O-[6-O(alpha-L-rhamnose base)-beta-D-glucosyl] kaempferide and kaempferol-3-glucoside is up to over 99 percent. The kaempferol which is over 100 times more than the former can be obtained from the gingko pollen by transformation. Thus, the bioavailability is greatly improved.
Owner:INST OF AGRO FOOD SCI & TECH SHANDONG ACAD OF AGRI SCI

Galangin extraction method

The invention relates to a method for fully utilizing a traditional Chinese medicine material to prepare high-purity galangin. The method comprises the following steps that intermediates with similar constitution ratios are combined multiple times; and dextran chromatography and methanol recrystallization are carried out, such that high-purity galangin is obtained. Compared to prior arts, according to the invention, galangin and kaempferide in a galangal total crude extract are separated with the dextran chromatography and methanol recrystallization methods, such that galangin purity can reach 98-99.5%; through scientific and reasonable fraction combination design, low-purity fractions and crude products in the separation purification process can be repeatedly utilized. Therefore, the medicine material resource is fully utilized, cost is saved, and operation is convenient. With the method, it is possible to develop galangin into a medical raw material and especially a raw material medicine for traditional Chinese medicine injections and Chinese patent medicines.
Owner:SHANGHAI U SEA BIOTECH

HPLC detection method for alpinia-cyperus preparations

The invention discloses an HPLC detection method for alpinia-cyperus preparations. The HPLC method is used for simultaneous determination of the contents of 5 components, namely galangin, kaempferide, sweet ketene, nootkatone and alpha-cyperone, in the alpinia-cyperus preparations. The HPLC method comprises the following steps: (1) establishing a standard curve of galangin, kaempferide, sweet ketene, nootkatone and alpha-cyperone; (2) determining the contents of galangin, kaempferide, sweet ketene, nootkatone and alpha-cyperone in a sample to be detected. According to the HPLC detection method provided by the invention, various components in the alpinia-cyperus preparations can be determined simultaneously. The HPLC method is high in specificity, can comprehensively reflect information, is simple and convenient, quick and accurate, and is accurate and reliable in determination result, so that the quality of the alpinia-cyperus preparations can be effectively monitored, and the medicine safety is improved.
Owner:CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE

Method for detecting quality of niaolukang particles

The invention discloses a method for detecting quality of niaolukang particles. The formula of the niaolukang particle is as follows: preparing 1000g of leonurus, 1000g of eclipta, 1000g of plantago asiatica, 300g of junci medulla, 1000g of desmodium, 200g of liquorice, 1000g of rhizoma polygonati and 500g of rhizoma dioscoreae into granular formulation. In the method, quercetin (C15H1107) and kaempferol (C15H10O6) in desmodium are taken as a quality control index, and compared with stachydrine in the leonurus, the ingredients are stable in property, and generate small detection error. In addition, the high performance liquid chromatography is utilized for measuring content, so that the resolution rate is higher than that of other chromatography, the speed is high, and the measurement can be completed in ten minutes to dozens of minutes; the repeatability is high; a high performance liquid chromatography column can be used repeatedly; and the automatic operation is conducted, and the analysis accuracy is high. Therefore, the accuracy, the specificity and the credibility of a detection result in the quality control process of products are improved.
Owner:唐秋海

Detection method of persimmon leaf quality

The invention provides a detection method of persimmon leaf quality; which is characterized in that: the method comprises the following steps: sample solution preparation: the persimmon leaf powder to be detected is taken out and mixed with methyl alcohol to obtain a first mixed solution which carries out ultrasonic wave treatment to filter the first mixed solution, and the obtained filtrate is concentrated to obtain test article solution; kaempferide, quercetin and methanol are mixed to obtain a second mixed solution which is used as reference substance solution; detection: the sample solution is measured by thin layer chromatography, the chromatograph of the test article is observed weather to display the spots with same color with the reference substance at the same position of the chromatograph of the reference substance solution. If yes, the persimmon leaf powder to be detected is determined to contain the kaempferide and the quercetin; compared with the method that the persimmon leaf quality is determined by the characteristics in the prior art, the detection method can accurately determine the drug effective ingredients of the persimmon leaf to be detected.
Owner:GUANGZHOU BAIYUSN HUTCHISON WHAMPOA CHINESE MEDICINE

Method for measuring content of components of prince's-feather herb

The invention provides a method for measuring content of components of prince's-feather herb and belongs to the technical field of medicament content measurement. High performance liquid chromatography is adopted to measure the content of eight compounds, namely catechin, homo-orientin, orientin, quercetin-3-O-(2'-O-alpha-rhamnose)-betal-glucal, texifolin, luteolin-7-O-beta-D-glucoside, quercetin and kaempferide-3-0-beta-3-D-glucoside, in the prince's-feather herb under the same chromatographic condition. Compared with the conventional single component content measuring method, the method of the invention is more integral, characteristic and stable, and provides test basis for further improving the quality of the prince's-feather herb and the re-development and application of the prince's-feather herb. The invention also provides the methods for preparing reference solution and test sample solution.
Owner:GUIYANG MEDICAL UNIVERSITY

Detection method for flavone component in clematis filamentosa dunn, and application thereof

ActiveCN102426207AThe content accurately reflectsStrong specificityComponent separationClematisKaempferide
The present invention discloses a detection method for a flavone component in clematis filamentosa dunn, and an application thereof. According to the present invention, a kaempferide-containing methanol solution is adopted as a reference substance solution; a high performance liquid chromatography method is adopted to carry out qualitative and / or quantitative analysis for the flavone component in a prepared clematis filamentosa dunn solution requiring detection. The method of the present invention can be applicable for detections of the flavone component in extracts, preparations, decoction pieces or medicinal materials, and no interference is generated to the negative result, wherein the extracts contain the clematis filamentosa dunn component, and the extracts are prepared by the same or the similar extraction methods. In addition, the method of the present invention has strong specificity and good reproducibility, such that the uniform, stable, effective and controllable preparation assortment of the clematis filamentosa dunn can be effectively ensured, and the process normalization, the quality stability and the quality uniformity are ensured.
Owner:SOUTH CHINA AGRI UNIV

Novel compounds with radioprotective effects and preparation method and pharmaceutical use thereof

The present invention provides novel compounds with radioprotective effects and pharmaceutically acceptable salts, prodrugs, and solvates thereof as shown in formula (I). Ar is selected from astaxanthin, anthocyanins, proanthocyanidins, resveratrol, VitaminA, VitaminC, VitaminE and flavonoids such as apigenin, luteolin, kaempferide, quercetin, glycyrrhizin, hesperidin, dihydroquercetin, Dihydromorin, (+) catechin, (-) epicatechin, ginkgetin, Ophiopogonone A, rubrofusarin, baicalein and the like, R1 is selected from the following groups shown in the specification, further, the present invention provides a preparation method and use of the compounds and the derivatives thereof in treatment of radiation injuries.
Owner:SHANGHAI KECHOW PHARMA

Preparation method of molecular imprinting adsorption material for kaempferide on surface of cotton bast

The invention discloses a preparation method of a molecular imprinting adsorption material for kaempferide on the surface of cotton bast. The preparation method is characterized by comprising the following steps: modifying the surface of the cotton bast through gamma-trimethoxysilyl propyl methacrylate, thus obtaining surface-modified cotton bast; adding 50 to 60 percent of ethyl alcohol, 8 to 14 percent of ethylene glycol dimethacrylate, 4 to 8 percent of 4-vinyl pyridine, 3.0 to 8.0 percent of the kaempferide, 15 to 22 percent of the surface-modified cotton bast and 1.0 to 3.0 percent of azodiisobutyronitrile into a reactor, stirring and dissolving the components, feeding an inert anaerobic atmosphere, performing stirring reaction, and removing template modules with a methyl alcohol and acetic acid mixing solution, thus obtaining the molecular imprinting adsorption material for the kaempferide on the surface of the cotton bast. The adsorption material has specific identification capacity for the kaempferide, is relatively high in selectivity, high in mechanical property, extremely high in chemical stability, high in adsorption speed, easy to elute, biodegradable and simple in process, and has the advantages of regeneration capacity, environment friendliness and the like.
Owner:UNIV OF JINAN

Enzyme-rich blood replenishing four herbs decoction and preparation method thereof

The invention discloses enzyme-rich blood replenishing four herbs decoction and a preparation method thereof. The four herbs decoction is mainly prepared from angelica sinensis extract, ligusticum chuanxiong hort extract, Chinese herbaceous peony extract, prepared rehmannia root extract, a plant enzyme magnetized solution, A-methyl ursolate, kaempferide, hydroxyethyl cellulose and chicken soup. The preparation method includes the following steps that 1, angelica sinensis extract, ligusticum chuanxiong hort extract, Chinese herbaceous peony extract, prepared rehmannia root extract, a plant enzyme magnetized solution, A-methyl ursolate, kaempferide, hydroxyethyl cellulose and chicken soup are selected according to the proportion for use; 2, all the extract are stirred and mixed evenly to obtain mixed liquid; 3, the mixed liquid, the adjuvants, the ingredients and the plant enzyme magnetized solution are sequentially added into the chicken soup to obtain blood replenishing four herbs decoction. The prepared blood replenishing four herbs decoction can replenish blood for women without causing blood stasis, the body recovery effects of the women are increased, and the absorption of theintestinal tracts of the women to nutrient components and various components of the blood replenishing four herbs decoction is improved.
Owner:谭建新

Medicinal preparation containing albizia flower total flavone

The invention provides a medicinal preparation containing albizia flower total flavone and medical application. The albizia flower total flavone contains the following components in percentage by weight: 41-50 percent of quercitrin, 0.1-10 percent of quercetin, 0.1-5 percent of kaempferide, 0.1-2 percent of quercetin-3-0-alpha-L-arabinoside, and quercetin-3-0-alpha-L-arabinoside. The invention also discloses a method for preparing the albizia flower total flavone medicinal preparation with high dissolution rate, as well as application of the albizia flower total flavone and medical preparation thereof serving as basic active substances in preparing a medicine for treating depression.
Owner:BEIJING SL PHARMA +1

Method for extracting and detecting flavonoids from galangal

The invention belongs to the field of natural compound extraction, and particularly relates to a method for extracting and detecting flavonoids from galangal. In the prior art, subcritical extractionof the flavonoids in galangal mostly adopts an organic solvent as an extraction reagent or is combined with ultrasonic extraction. The method only adopts subcritical water as the extraction reagent, and studies the optimum preparation conditions for extraction of seven substances of quercetin, pinocembrin, isorhamnetin, kaempferol, kaempferide, galangin and curcumin. A galangal extract obtained bythe preparation method can be directly applied to an oral preparation due to the fact that an organic reagent is not introduced during the preparation process. In addition, a high-performance liquidphase detection condition for the galangal extract is provided, and can simultaneously detect flavonoid compounds, and the repeatability is good. The extract and the method are applied to the preparation of cardiovascular drugs and have important production significance.
Owner:SHANDONG ANALYSIS & TEST CENT

Preparation for improving activity and/or thermal stability of superoxide dismutase and application of preparation

The invention provides a preparation for improving activity and / or thermal stability of superoxide dismutase and an application of the preparation. The preparation comprises at least one of catechin, quercetin, myricetin, kaempferol, ellagic acid and ferulic acid. The quercetin, the myricetin and / or the kaempferol contained in the preparation can effectively improve the activity and the thermal stability of the superoxide dismutase, and the superoxide dismutase is endowed with a relatively wide application prospect.
Owner:CHINA AGRI UNIV

Method for making a pot-stewed chicken having health-care function

InactiveCN107183554ABright colorTaste saltyFood scienceBiotechnologyQuercetin
The invention discloses a method for making a pot-stewed chicken having the health-care function. Before being marinated, a washed chicken is soaked in a Chongcha tea solution for 1-5 hours, and then the surface of the chicken is drained after soaking is completed. Chongcha tea components are added in the method for making the pot-stewed chicken having the health-care function, and according to scientific research, it is confirmed that the Chongcha tea is rich in more than ten kinds of amino acids and trace elements, such as calcium, magnesium, zinc, selenium, flavone, tea polyphenols, catechins, glycosides, quercetin, rhamnose, glutamic acid, kaempferide, myricetin, alanine, biological fungi and apione, necessary for the human body. The chicken is tasty, delicious, attractive and refreshing and has the pharmaceutical functions of whetting the appetite, tonifying the spleen, refreshing, dispelling the effects of alcohol, removing toxins, clearing away heat, reducing blood pressure and the like. The made chicken is bright in color, dense, solid, salty and spicy in taste and tender in meat and has an unique health-care effect.
Owner:贵州奇垦农业开发有限公司

Ginkgo leaf total flavone controlled-release tablet and preparation method thereof

The invention belongs to the technical field of medicines, and particularly discloses a ginkgo leaf total flavone controlled-release tablet and a preparation method thereof. The controlled-release tablet disclosed by the invention is a tablet which is prepared by combining polyoxyethylene and a controlled-release skeleton material and adopting a conventional tablet preparation technology and has the zero-order release behavior characteristic. The controlled-release tablet consists of an active ingredient ginkgo leaf total flavone, a high polymer material polyoxyethylene (PEO), the controlled-release skeleton material and a certain amount of release rate conditioning agent. The active ingredients of the ginkgo leaf total flavone mainly comprise isorhamnetin, kaempferide and quercetin, and the total flavonoid glycoside content of the quercetin is not lower than 20%. Compared with a common tablet, the ginkgo leaf total flavone controlled-release tablet has the advantages that the controlled-release tablet can be used for maintaining the constancy of the blood concentration, reducing the adverse reactions of the medicines and improving the compliance of the patients. The preparation method is simple in technological operation, low in cost, easy to control and suitable for industrial large-scale production.
Owner:SHENYANG PHARMA UNIVERSITY

Application of methoxy flavonoid compound in preparation of anti-vitiligo medicine

The invention discloses an application of methoxy flavonoid compound in preparation of anti-vitiligo medicine. According to the application of the methoxy flavonoid compound in preparation of the anti-vitiligo medicine, the methoxy flavonoid compound with 2-phenylchromone mother nucleus has an anti-vitiligo effect and represents compounds including kaempferide, isorhamnetin and kaempferol 3, 4 '-dimethyl ether. The methoxyflavone compound promotes regeneration and neogenesis of melanocytes and induces accumulation of melanin by promoting expression of key genes in a melanogenesis pathway, and maintains melanin steady state and reduces decomposition of original melanin cytochrome by up-regulating expression of melanin steady state related protein adcy6; meanwhile, the increase of active oxygen under physiological dose is induced, the expression of glutathione synthesized gclm, gclc and other related genes is down-regulated, melanin metabolism is reduced, so that the effect of treating vitiligo is achieved, and the methoxy flavonoid compound has important value and development prospect in the research and development of vitiligo treatment medicine.
Owner:张波

Pharmaceutical composition and preparation method thereof

The invention discloses a pharmaceutical composition and a preparation method thereof. The pharmaceutical composition comprises a phenoloid, sterol, a flavonoid, amino acid, tannin, volatile oil, choline, sylvite, a glucoside compound and a lactone compound. The flavonoid comprises quercetin and kaempferide. Compared with the existing drug, the pharmaceutical composition is convenient for carrying, is a pure traditional Chinese medicine preparation, and has small side effects and taking safety.
Owner:SICHUAN TIANSHOU PHARMA

Polyvinyl chloride cable material with excellent flame resistance and preparation method thereof

The invention discloses a polyvinyl chloride cable material with excellent flame resistance. The polyvinyl chloride cable material is prepared from the following raw materials in parts by weight: 110to 115 parts of polyvinyl chloride resin, 4 to 8 parts of acetylene carbon black, 1 to 2 parts of an anti-aging agent, 5 to 9 parts of a flame retardant, 0.7 to 1.0 part of kaempferide, 2 to 5 parts of triaryl phosphate, 3 to 6 parts of chlorinated paraffin, 2 to 5 parts of epoxidized soybean oil, 1 to 2 parts of barium stearate, 1 to 3 parts of toner, 6 to 10 parts of a rare earth stabilizer, 11to 16 parts of calcium carbonate, and 17 to 21 parts of dioctyl terephthalate. The invention further discloses a preparation method of the polyvinyl chloride cable material with excellent flame resistance. The cable material has flame resistance and excellent mechanical property, can meet the market demand, is beneficial to the improvement of safety performance of wires and cables, and has a widemarket prospect.
Owner:宁夏中科天际防雷研究院有限公司

Preparation method of herba lysimachiae granules

The invention provides a preparation method of herba lysimachiae granules. The preparation method comprises the steps of adopting herba lysimachiae as a raw material; adopting water (90 to 95 DEG C) for forcedly and dynamically recycling extracting for three times; vacuum concentrating an extracting solution to obtain a herba lysimachiae extract; adding appropriate pharmaceutic adjuvant and appropriate amount of flavoring agent for highly dispersing, and then preparing to form mixed dry extract powder through a vacuum low-temperature continuous drying technology; adding ethyl alcohol for stirring and mixing to obtain the granules. According to the preparation method adopted by the invention, the contents of quercetin and kaempferide in the herba lysimachiae granules can be remarkably improved, and the increased range achieves 250 percent; the dosage of the commercially available herba lysimachiae granules for every time can be reduced by not less than 70 percent, so that the patient adaptability is greatly improved; the operation cost can be reduced by not less than 1 / 3, the energy consumption can be reduced by not less than 40 percent, and the modernization of a traditional Chinese medicine can be fully reflected.
Owner:CHONGQING KERUI PHARMA GRP

Method for identifying cyclocarya paliurus

The invention discloses a method for identifying cyclocarya paliurus. The method comprises the following steps: (1) preparing a test solution; and (3) respectively preparing a methanol solution of kaempferide and a methanol solution of quercetin as reference substance solutions, respectively dripping the two reference substance solutions and the test solution on the same silica gel G thin-layer plate, developing by using dichloromethane-ethyl acetate-formic acid as a developing solvent, taking out, airing, spraying an ethanol solution of aluminum trichloride, heating the sample solution in the environment of 105 + / -5 DEG C until the spots are clearly developed, placing the sample solution under an ultraviolet lamp for inspection, and when the fluorescent spots in the chromatogram of the sample solution can find the corresponding fluorescent spots in the corresponding position of the chromatogram of one of the two reference substance solutions, determining that the powder to be detected is cyclocarya paliurus powder. The method is high in cyclocarya paliurus identification accuracy, meanwhile, the content of kaempferide in cyclocarya paliurus can be measured, the quality grade of cyclocarya paliurus can be evaluated, operation is easy, reaction is fast, and rapid detection and evaluation of the quality of cyclocarya paliurus are achieved.
Owner:轩豪益邦制药有限公司

Sliced noodle seasoning, sliced noodle seasoning packet and preparation method

The invention provides a sliced noodle seasoning, a sliced noodle seasoning packet and a preparation method, and relates to the technical field of foods and ingredients thereof. The sliced noodle seasoning is prepared from the following components in parts by weight: 0.5-1.5 parts of kaempferide, 0.05-0.15 part of clove, 0.4-0.8 part of fennel, 0.4-0.8 part of Amomum tsao-ko, 0.3-0.7 part of cinnamon, 0.3-0.5 part of angelica dahurica, 0.4-0.8 part of Chinese prickly ash, 0.3-0.5 part of pepper, 1.0-2.0 parts of star anise, 0.2-0.4 part of costus root, 0.3-0.5 part of rhizoma nardostachyos, 0.1-0.3 part of hay, 0.4-0.6 part of Pictocarpus heterophyllus, 0.5-0.9 part of dried orange peel, 0.5-0.9 part of katsumade galangal seed and 0.3-0.7 part of Amomum Kravanh Pierre ex Gagnep. In addition, the invention also provides the sliced noodle seasoning packet and the preparation method thereof. According to the seasoning for the sliced noodles, the spices in a specific ratio are selected forclearing damp, tonifying spleen, warming middle warmer and nourishing stomach, so that the finally prepared sliced noodles are extremely good in flavor, sufficient in fragrance, stable in taste and suitable for being used in families, the taste of the prepared sliced noodles is not inferior to that of sliced noodles eaten outside, and the operation is simple and convenient. The sliced noodle seasoning packet provided by the invention is more convenient than the sliced noodle seasoning.
Owner:冯太平

A preparation method for detecting kaempferol molecularly imprinted sensor

The invention discloses a method for preparing a sensor for detecting kaempferide molecular imprinting. The method is characterized in that first chloroauric acid and graphene oxide to modify a glassy carbon electrode, and obtaining a nanogold graphene-modified glassy carbon electrode; adding 44-50% of ethanol, 10-14% of ethylene glycol dimethacrylate, 5-8% of styrene, 30-35% of 1-vinyl-3-butyl hexafluorophosphate, 1.0-2.0% of azodiisobutyronitrile and 2.0-5.0% of kaemperfol into a reactor, performing mixing and dissolution, perform stirring reaction for 28-30 h at 55+ / -2 DEG C, adopting methanol : acetic acid mixed solution to remove template molecules to obtain kaempferide molecularly imprinted polymer; dispensing the molecularly imprinted polymer to the nanogold graphene-modified glassy carbon electrode, and obtaining the kaempferide molecular imprinting sensor. The sensor is high in compatibility and selectivity. The sensor is high in sensitivity and good in specificity, has quickness in detection and can be reused.
Owner:UNIV OF JINAN

Gingko general flavone sublingual tablet and preparation method thereof

The invention discloses a gingko general flavone sublingual tablet and a preparation method thereof.The sublingual tablet is prepared from, by weight, 1-260 parts of gingko general flavone, 2-25 parts of disintegrating agent and 35-245 parts of filler.Gingko general flavone is prepared from, by weight, 35-50% of quercetin, 6-16% of kaempferide and 15-25% of isorhamnetin.The gingko general flavone sublingual tablet is prepared by organically combining disintegrating agent with filler, and the tablet is put under a tongue when taken and can be rapidly disintegrated and absorbed by sublingual mucosal and directly enter blood circulation through jugular veins and superior vena cava to rapidly act so as to rapidly relieve migraine symptoms.Meanwhile, the tablet is particularly suitable for the aged and other patients having difficulty in swallowing and patients having difficulty in taking water in special environments such as battlefields, outdoor environments and tourist environments.
Owner:HUNAN UNIV OF SCI & ENG +1
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