182 results about "Autoinjector" patented technology

An autoinjector system for injecting a fluid medicament into a patient includes a re-usable autoinjector, and a disposable cassette loaded with a hypodermic syringe pre-filled with a fluid medicament. The autoinjector includes a first motor for injecting a needle of the hypodermic syringe into the patient and a second motor for expelling the fluid medicament from the syringe.

The invention provides a syringe or autoinjector for dispensing a drug comprising a rigid syringe body containing the drug, an oxygen absorbing material, a separating element between the drug and oxygen absorbing material to prevent the drug from contacting the oxygen absorbing material but which allows oxygen to pass from the drug to the oxygen absorbing material, and an oxygen impermeable container enclosing both the drug and the oxygen absorbing material, wherein the oxygen impermeable container partially or fully forms the rigid syringe body or is held within the rigid syringe body.

An autoinjector comprising a housing in which can be mounted a syringe comprising a barrel for holding a volume of medicament, a needle at one end of the barrel in fluid communication with the medicament and a plunger axially-moveable in the barrel to a forwardmost position, the autoinjector further comprising a syringe support means for supporting the barrel at an axial location at or forward of the forwardmost position of the plunger and having a reaction surface for the syringe, whereby in use said reaction surface (109) provides an axial compressive force on said barrel when a forward axial force is applied to the plunger.

An autoinjector device for delivering a dose of medicament including a syringe including a needle wherein, prior to use of the device, the needle is substantially covered by a needle sheath (107). The autoinjector further includes a housing (112) in which said syringe is located, an outer packaging in which said housing is located, where the outer packaging comprising a front packaging (101) part and a rear packaging part. The autoinjector also includes needle sheath removing means (103) associated with said front packaging part (101), wherein, prior to use of the device, said front and rear packaging parts cooperate together to entirely enclose said housing, syringe and needle sheath, and wherein, upon axial separation of said front and rear packaging parts, said needle sheath removing means is capable of causing axial separation of said needle sheath from said needle so as to remove said needle sheath therefrom.

The invention provides a delivery mechanism for an autoinjector comprising: a first drive member configured to drive a first component in an axial direction; a second drive member configured to drive a second component in an axial direction; and a release mechanism configured to control a sequence of release of the first drive member and the second drive member, wherein the release mechanism is positioned at least partially within the first or second drive member.

The invention provides a drive mechanism for an autoinjector, configured to be coupled to a drug containing portion to form a complete autoinjector, the drive mechanism comprising: a housing (20); a drive means coupled to the housing, the drive means comprising a resilient member (22); a retaining means coupled to the housing, the retaining means (60) engaging the drive means in a first position to retain the resilient member in a deformed condition, and releasing the drive means in a second position; and a coupling means (24) for coupling with a drug containing portion (10). The drug containing portion retains the drive means in a second deformed condition when the retaining means is in the second position, the drive means storing enough energy in the second deformed condition to drive needle insertion and/or drug delivery.

The present invention provides for an autoinjector that registers off a distal end of a syringe to provide for a more accurate needle insertion depth. The autoinjector employs an automatically deployable frontal buttress for registration of the distal end or shoulder of the syringe.

The present invention provides a reusable spring driven autoinjector. The drive mechanism of the autoinjector of the present invention includes one or more drive springs formed of a shape memory alloy. Therefore, by alternating the shape memory alloy forming the one or more drive springs between austenite phase before an injection and a martensite phase after injection, the reusable autoinjector of the present invention is capable of providing an injection force that is higher than the compressive force required to cock the drive mechanism in preparation for a subsequent injection operation.

An autoinjector including: a housing, in which can be mounted a syringe (28) having a plunger, a barrel and needle (19) at one end thereof through which medicament can be delivered to an injection site,—a syringe support means (30) capable of causing said syringe to move along an axial path with respect to said housing; biasing means capable of biasing said syringe support means so that said needle is normally inside said housing; and engagement means (180) selectively moveable by a user from a first position in which rearward movement of the syringe along said axial path is substantially prevented when said syringe is in an extended position where at least part of said needle is out of the housing, to a second position in which rearward movement of the syringe along said axial path relative to said housing is possible and said biasing means causes said needle to retract inside said housing; wherein said housing includes an outer housing (16) and said autoinjector further comprises a sleeve (18) intermediate the syringe support means and said outer housing that is capable of moving the engagement means between said first and second positions by rotating said sleeve about a longitudinal axis of said autoinjector between a first rotational position and a second rotational position; and wherein the sleeve is moveable between said first and second rotational positions by moving said outer housing with respect to the sleeve in a substantially axial direction.

An injection device comprising an outer housing adapted to receive a syringe for holding a volume of a medicament, said syringe comprising a barrel, a needle at one end of the barrel, and a plunger, axially moveable within the barrel, the needle and barrel being such that at least part of the needle is axially moveable in and out of said outer housing but is biased to be normally wholly inside said housing. The injection device further comprises an inner housing intermediate the outer housing and at least part of the barrel and/or plunger, an energy source in communication with the inner housing, and blocking means capable of preventing said inner housing moving axially under the influence of said energy source. The device is moveable between two positions, namely a first position in which the inner housing is prevented from moving axially forward by engagement with said blocking means; and a second position in which the inner housing is disengaged from said blocking means and is capable of acting on the syringe under the influence of said energy source to move said at least part of the needle out of said outer housing. The device is moveable from said first position to said second position by movement of said outer housing relative to said inner housing and actuation of a trigger.

The invention relates to an automatic injection device (1) including: a container (6) provided with a needle (8); a housing (3) receiving a container (6) movable relative to the housing (3) between an initial position to an insertion position; a needle shield (12) for receiving the needle (8) and in which the needle (8) is embedded prior to use of the device (1); and, a deshielder (33) coupled to the needle shield (12) by a first connecting arrangement (51) and removably assembled to the distal part of the housing (3) by a second connecting arrangement (44, 45a, 45b, 57). The first and second connecting arrangements are designed so that a rotational movement of the deshielder (33) about the device axis (2) of the device (1) with respect to the housing (3) causes an axial displacement of the needle shield (12) in the distal direction with substantially no rotational movement of the needle shield (12) with respect to the needle (8).

Disclosed are systems and methods of detecting an impulse of energy given off by an injection device and determining a dosage of medicine based on the impulse. In one example, a module detects the vibrations given off by dialing a click-wheel on an autoinjector and determining the selected dosage of medicine based on the dialed dosage.

An autoinjector comprising an outer housing in which can be mounted a syringe for holding a volume of medicament, the syringe for holding medicament having a needle at one end thereof, a syringe holder for supporting the syringe in an axial position relative to the outer housing, and an intermediate housing at least part of which is located within said outer housing, characterised in that said intermediate housing is provided with a blocking means capable of abutting the syringe or the syringe holder so as to be capable of preventing forward axial movement of the syringe when a forward axial force is applied to said needle before actuation of the autoinjector to deliver an injection, but incapable of preventing forward axial movement of the syringe during actuation of the autoinjector to deliver an injection.

The invention relates to an automatic injection device (1) for a product contained in a container (50), comprising: - a housing (8, 19) receiving the container (50), the container being movable between an initial position and an insertion position, - triggering means (23) for initiating the movement of said container (50) from its initial position to its insertion position, said triggering means (23) being in one of a passive state, in which application of a force on said triggering means does not initiate movement of said container (50), and an active state, in which application of said force on said triggering means does initiate said movement, and - a safety shield (10) movable with respect to said housing (8, 19) between a first position and a second position, movement of said safety shield (10) from its first position to its second position placing said triggering means (23) in its active state, characterized in that said device comprises: an indicator (19c, 13) that provides an indication to a user of the device (1) that the safety shield (10) has reached its second position.

Chemical engines and processes for their use and construction are described. The chemical engines can provide powerful and compact devices, especially autoinjectors for the rapid, powered injection of viscous medicines. Novel formulations and designs of chemical engines and delivery technologies employing the chemical engines are described.

An injection device, method, and system for drug delivery includes a primary container for storing a drug, the container having a stopper movably disposed in the container for expelling the drug, an injection drive mechanism comprising a plunger for acting on the stopper and an energy source for exerting a force on the plunger to cause the plunger to act on the stopper to expel the drug, the force causing the plunger to accelerate to a velocity prior to acting on the stopper, and a damping mechanism for reducing the velocity of the plunger prior to acting on the stopper. The damping mechanism can include a dashpot or an energy absorbing material associated with the plunger. Alternatively or additionally, the damping mechanisms can include absorbing material disposed between support members of an outer casing of the injection device and the primary container.

An autoinjector device comprises a drive housing 10 and a syringe housing 12 which can be disconnected to allow insertion of a syringe. A drive mechanism in the drive housing is cocked by means of a cord 8 connected between the drive housing and the syringe housing. The drive mechanism comprises a drive gear 22 rotatably mounted in the drive housing and acting as a rotary crank connected by a connecting rod 26 to a plunger 28. In use the drive gear 22 is driven by a torsion spring 35 so that the drive mechanism extends the syringe from the syringe housing and expels a dose and then retracts the syringe back into the housing. A firing button 14 releases the drive gear to be driven by the torsion spring but is also engageable as a brake on the rim of the drive gear.

An injection device, in some embodiments an autoinjector, which includes a housing, an actuating sleeve carried by the device to be movable relative to the housing and which can be placed at a point of injection in a position of insertion, an injection needle extendable from the end of the injection device when the injection device is in the position of insertion and moveable into the interior of the injection device, and an actuating cam arranged in an axially fixed manner relative to the injection needle and engageable in a locking recess when the injection device is in the position of insertion to prevent the injection needle from being moved into the interior of the injection device, said actuation cam being releasable from engagement with the locking recess by the actuating sleeve, thereby releasing the injection needle for movement into the injection device.

Described is an autoinjector comprising a case, a door hingedly coupled to the case and having an open position and a closed position, a plunger slidably disposed in the case, and at least one drive spring applying a biasing force on the plunger relative to the case, wherein the door is operably coupled to the plunger, and wherein rotation of the door from the closed position to the open position moves the plunger from a distal position in the case to a proximal position in the case and compresses the at least one drive spring.

An autoinjector includes a main body having a container, the container having a drug therein, a hollow needle coupled to the container through which the drug can be delivered. The autoinjector also has a power source having a liquefied gas therein as a driver, a flow regulator, and at least one outlet through which some of the driver can exit the power pack in a gaseous state. The power source and container are coupled together for operation such that, when an injection is initiated, the flow regulator will control an exit rate of the driver such that the liquefied gas in the power source is maintained at substantially its vapor pressure and the power source will adjustably apply a force to deliver the drug via the hollow needle at a delivery rate that is a constant delivery rate.

Describe is an autoinjector (1) comprising a case (2) adapted to hold a medicament container having a needle (4), a needle shroud (7) telescopically coupled to the case (2) and movable between a first extended position (FEP) relative to the case (2) in which the needle (4) is covered and a retracted position (RP) relative to the case (2) in which the needle (4) is exposed, and a plunger (10) rotationally and slidably disposed in the case (2). The plunger (10) is rotatable relative to the case (2) between a first rotational position in which the plunger (10) is engaged to the case (2) and a second rotational position in which the plunger (10) disengages the case (2). The needle shroud (7) is operably coupled to the plunger (10). When the needle shroud (7) translates from the first extended position (FEP) to the retracted position (RP), the plunger (10) rotates from the first rotational position to the second rotational position.

The present disclosure provides methods of preparing a medical solution. In some aspects, the medical solution can be prepared from mixing a first liquid with a second liquid or mixing a solid component with a liquid in an autoinjector. In some aspects, the heat released from the mixing can promote solubility of a dry medicament in the solution.