Patents
Literature
Patsnap Eureka AI that helps you search prior art, draft patents, and assess FTO risks, powered by patent and scientific literature data.

10 results about "Meta-analysis" patented technology

A meta-analysis is a statistical analysis that combines the results of multiple scientific studies. Meta-analysis can be performed when there are multiple scientific studies addressing the same question, with each individual study reporting measurements that are expected to have some degree of error. The aim then is to use approaches from statistics to derive a pooled estimate closest to the unknown common truth based on how this error is perceived. Existing methods for meta-analysis yield a weighted average from the results of the individual studies, and what differs is the manner in which these weights are allocated and also the manner in which the uncertainty is computed around the point estimate thus generated. In addition to providing an estimate of the unknown common truth, meta-analysis has the capacity to contrast results from different studies and identify patterns among study results, sources of disagreement among those results, or other interesting relationships that may come to light in the context of multiple studies.

Meta analysis method and device, equipment and storage medium

The invention discloses a Meta analysis method and device, equipment and a storage medium, according to the scheme, automatic semantic analysis is carried out on a research problem input by a user through a preset large language model, target literature is processed through a pre-training language model, an efficient and reliable automatic tool is provided for evidence-based medicine, and the efficiency is improved. According to the method, the dependency of Meta statistical analysis on professionals is reduced, the analysis period is shortened, personal errors are reduced, the intelligent degree, efficiency, accuracy and repeatability of Meta statistical analysis are remarkably improved, and standardized and intelligent development of evidence-based medical research is promoted; in addition, retrieval is carried out based on the target structured form, the retrieval strategy is optimized, the retrieval accuracy is improved, and therefore the performance and accuracy of Meta statistical analysis are further improved.
Owner:KUNMING MEDICAL UNIVERSITY

Compost maturity evaluation method and application

The invention provides a compost maturity evaluation method and application. According to the method, an optimized data set is provided for establishing an optimal prediction model for machine learning by performing Meta analysis data preprocessing. Determining thresholds of four internal maturity indexes suitable for the data set by adopting a statistical method; and calculating the maturity day number meeting the statistical maturity threshold value by using the optimal prediction model. And carrying out importance grade sorting on the four internal maturity indexes in the compost heap by using a K-means unsupervised clustering algorithm based on the statistical maturity threshold. And according to the importance grade sequence, an analytic hierarchy process (AHP) is used to establish weight endowing, maturity days of different indexes are multiplied by corresponding weights and summed, and the unified compost maturity evaluation days are obtained. According to the method, key support is provided for machine learning modeling by means of Meta analysis, the machine learning model and the analytic hierarchy process based on Kmeans unsupervised clustering are combined, a comprehensive evaluation framework of compost maturity is established, and a new thought is provided for maturing judgment of charcoal compost.
Owner:SICHUAN AGRI UNIV

Method for predicting probability or degree of occurrence of plant diseases and insect pests of single forest tree

The invention discloses a method for predicting the probability or degree of occurrence of plant diseases and insect pests of a single forest tree. The method comprises the following steps of: predicting the probability or degree of occurrence of the plant diseases and insect pests of the single forest tree by using a cluster index vi of SADIE (Spatial Analysis Distance Indices) as an explanatory variable. The prediction can be carried out on a global scale (the whole investigation area), and can also be carried out on a local scale (a circle taking a single forest tree as a circle center). When local scale prediction is carried out, investigation is carried out on a series of circles with different radiuses, models on different radius scales are established, and then a summary effect of coefficients is obtained by using a Meta analysis method for prediction. The method can provide a suitable prediction method for forest pest control work.
Owner:NORTHEAST FORESTRY UNIV

Method and device for screening venous thromboembolism risk factors of orthopedic trauma patient

The invention relates to the technical field related to medical treatment, in particular to a vein thromboembolism risk factor screening method and device for orthopedic trauma patients. The method comprises the following steps: acquiring original data; based on the original data, screening a first group of candidate risk factors related to venous thromboembolism of the orthopedic trauma patient by combining a plurality of data driving feature screening methods; based on literature review, determining a second group of candidate risk factors related to venous thromboembolism of the orthopedic trauma patient by using a meta analysis method; integrating the first group of candidate risk factors and the second group of candidate risk factors, identifying a causal relationship of the candidate risk factors based on a causal theory and a preset algorithm in combination with expert experience, and drawing a directed acyclic graph; and deleting the risk factors in the directed acyclic graph, which are in indirect causal relationship with venous thromboembolism of the orthopedic trauma patient, so as to obtain a target risk factor.
Owner:WEST CHINA HOSPITAL SICHUAN UNIV

Meta analysis intelligent topic selection system based on language large model and literature

The invention is suitable for the technical field of intelligent medicine, and provides a meta analysis intelligent topic selection system based on a language large model and literature, which comprises a multi-source literature library, a literature dynamic acquisition module, a literature panoramic analysis module, an intelligent topic selection generation module, a feasibility evaluation module and a scheme automatic generation module, the literature dynamic acquisition module comprises a multi-source data access unit, an incremental updating monitoring unit and an intelligent filtering and classifying unit; the intelligent topic selection generation module is used for evaluating the novelty and potential influence of topic selection based on the blank of existing research identification knowledge; the system further comprises a processing module, an enhancement module and an interaction module. The system provides intelligent topic selection suggestions for Meta analysis and research for researchers by combining a large language model and a literature mining technology, so as to solve the problems of low efficiency, incomplete coverage and lack of data support in the traditional Meta analysis topic selection process, shorten topic selection time, avoid omission risk of manual retrieval, and reflect the latest progress of the field in real time.
Owner:CHENGDU KNOWLEDGE VISION SCI & TECH CO LTD

Meta analysis method, system and equipment based on artificial intelligence and storage medium

The invention discloses a Meta analysis method, system and device based on artificial intelligence and a storage medium, and the method comprises the steps: receiving a natural language research problem inputted by a user, analyzing the natural language research problem, and generating a structured research framework according to an analysis result; constructing a retrieval formula based on the structured research framework, and retrieving literatures from the plurality of literature databases by using the retrieval formula to obtain a candidate literature set; and performing information extraction on the candidate literature set to obtain quantitative research data, and performing Meta analysis based on the quantitative research data to obtain a Meta analysis result. According to the method, the natural language research problem is analyzed, the structured research framework is generated according to the analysis result, the retrieval formula is constructed based on the structured research framework to retrieve literatures from the multiple literature databases, information extraction is performed on the candidate literature set, Meta analysis is performed based on the extracted quantitative research data, and the efficiency and accuracy of Meta analysis are improved.
Owner:PEKING UNIV

Micro-plastic pollution antibiotic resistance gene risk evaluation method based on relative abundance and absolute abundance

PendingCN122024824ABiostatisticsProteomicsMeta-analysisData collecting
The invention relates to the field of environmental antibiotic resistance gene (ARG) risk assessment, and aims to solve the problems that in existing research, microplastics are inconsistent in ARG abundance conclusion, and evaluation is one-sided only depending on relative abundance (abundance normalized with 16S rRNA gene and the like as a reference) or absolute abundance (abundance based on copy number). The invention provides a double-index collaborative risk evaluation method introducing Meta analysis. The method comprises the steps of data acquisition, index processing, Meta analysis and multi-factor adjustment, double-index interpretation and risk assessment and the like. By integrating ARG relative abundance and absolute abundance data of a micro-plastic exposure group and a control group and combining factors such as environment matrix, exposure time, particle size, concentration and type, the influence trend of micro-plastic on ARG abundance under different conditions is evaluated, the risk type is judged from a double-index perspective, and the accuracy and applicability of resistance risk evaluation are improved.
Owner:UNIV OF JINAN

Automatic data calculation method and system for hERG margin

The invention belongs to the technical field of drug safety pharmacology, and particularly relates to an hERG margin automatic data calculation method and system. The method comprises the following steps: step 1, calculating the statistical magnitude of hERG IC50 of a drug to be analyzed, wherein the statistical magnitude comprises a sample size, an arithmetic mean value, a lower limit and an upper limit of a 95% confidence interval, and a standard deviation; step 2, taking the statistics obtained in the step 1 as basic data, generating probability distribution of key parameters through Monte Carlo simulation, and calculating distribution of safety windows; and step 3, integrating data of all drugs to be analyzed, and obtaining overall safety window estimation through meta-analysis. The invention further provides a system for implementing the method. The method has the advantages of high efficiency, accuracy and accurate personalized calculation for special drugs, provides more scientific and reliable technical support for hERG safety window calculation and risk assessment, and has a good application prospect.
Owner:WESTCHINA-FRONTIER PHARMATECH CO LTD

Environmental micro-plastic ecological risk evaluation method based on data driving and normalization

The invention discloses an environmental micro-plastic ecological risk evaluation method based on data driving and normalization, and belongs to the technical field of micro-plastic environmental risk evaluation, and the method comprises the steps: collecting and integrating micro-plastic exposure experiment data, carrying out response ratio normalization processing and Meta analysis, carrying out p value inspection and effect quantity threshold inspection, and identifying significant response species. Screening sensitive species and sensitive effect indexes, traversing a machine learning classification algorithm, taking parameters of a micro-plastic exposure experiment as input features and taking whether the effect is significant as output, forming a supervised learning data set, training a machine learning classifier, carrying out deep analysis by utilizing a model interpretable method, and quantifying and normalizing a required effect threshold value. The method comprises the following steps: establishing a toxicity equivalent model, performing equivalent concentration conversion of microplastic combinations with different characteristics according to different effect threshold ratios, comparing the equivalent concentration with an effect threshold of standard microplastic, determining ecological risks, evaluating microplastic environmental risks, and providing a scientific basis for pollution management and control.
Owner:NANJING UNIV

Meta analysis of RCT outcome indicator structure analysis and computable input method and system

This invention discloses a method and system for analyzing and computable input of outcome indicators in meta-analysis RCTs, relating to the fields of medical statistics and literature data processing. The method first organizes a set of statistical elements with outcome indicators, detection time points, and comparison relationships as their scopes; then, it abstracts the meta-analysis formula into statistical element slot templates and performs slot matching within the outcome scope; when a target slot is missing, it is filled in based on preset substitution rules; after computability verification, a standardized meta-analysis input structure is generated. This invention solves the problems of existing technologies where meta-analysis data preparation is highly dependent on manual processes, computability verification is difficult to automate, and missing elements cannot be automatically filled in. It transforms manual judgment and calculation into a reusable structured process, significantly improving the efficiency, consistency, and data utilization of large-scale RCT outcome data processing. The output standardized data can be directly used by existing meta-analysis software.
Owner:JIEHELIX (SHANGHAI) MEDICAL TECH CO LTD +1