This invention belongs to the field of
nutritional composition technology, specifically relating to a composition, composition formulation, preparation method, application, and product for improving
bone health. This invention provides a composition composed of N-
acetylglucosamine and 3-O-acetyl-11-keto-β-
boswellic acid. The composition and formulation of this invention can promote the differentiation of
chondrocyte precursor cells into mature chondrocytes, promote
cartilage matrix synthesis, significantly inhibit TNF-α and MMP13 expression, and upregulate COL2A1 expression, with effects superior to single components and traditional combinations. The ingredients are natural and safe, biocompatible, and have no significant
toxicity, making them suitable for people with joint
noise,
joint pain,
osteoarthritis, and joint degeneration. Simultaneously, they can improve
bone density, promote
bone growth and development, and improve
bone health. The preparation process is simple and low-cost, and it can be formulated into various dosage forms such as food, health products, and pharmaceuticals, offering flexible applications and combining preventative and therapeutic value.