The invention provides a respiratory control locating device for breast tumor radiotherapy. The locating body rack of the device is an approximate case body with a hollowed rear wall, a case inner wall comprising a front wall, a left wall, a right wall, an upper wall and a lower wall of the case body is connected with a latex water bag, the upper wall, the lower wall and the front wall of the case body can be regulated in respective axial directions, a liquid control device is communicated with the water bag through a case body wall, the port of a suction device is positioned on the inner side of the water bag, a sub-controller is arranged on the case body, a main controller is respectively connected with the suction device, the liquid control device and the sub-controller, the case body is a carbon fiber case body, the water bag is internally connected with f the front wall, the left wall, the right wall, the upper wall and the lower wall of the case body through a plurality of connecting points, the suction device comprises a suction pump and a gas delivery pipe connected with a gas valve, and the liquid control device comprises a liquid pump, a liquid delivery pipe connected with the liquid pump and a water container communicated with the liquid delivery pipe.